Prof. Dr. Xufeng Huang | Neuroscience of Obesity and Schizophrenia | Neuroscience Academic Excellence Award

University of Wollongong | Australia

Professor Xufeng Huang is an internationally recognised molecular neuroscientist whose research integrates brain biology, metabolism, psychopharmacology, and nutritional science to address major public health challenges. His work has elucidated central molecular mechanisms of diet-induced obesity, including leptin resistance, neural injury, and cognitive decline, and translated these discoveries into preventive and therapeutic strategies. He has led pioneering research on antipsychotic-induced metabolic disorders in schizophrenia, identifying key neurotransmitter and receptor pathways and advancing safer pharmacological and adjunctive interventions. Professor Huang has also driven innovation in functional nutrition, notably the discovery and clinical validation of β-glucan as an effective dietary fibre for metabolic syndrome control, influencing dietary guidelines and policy. With extensive leadership of NHMRC-funded programs and international collaborations, his research spans mechanistic discovery, animal and human studies, and clinical translation. His contributions have shaped evidence-based interventions in brain health, obesity, metabolic disease, and severe mental illness, with sustained impact on clinical practice, policy development, and translational research across Australia and internationally.

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Featured Publications

Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice
– S Lin, TC Thomas, LH Storlien, XF Huang, International Journal of Obesity, 2000

Effects of dietary fat types on body fatness, leptin, and ARC leptin receptor, NPY, and AgRP mRNA expression
– H Wang, LH Storlien, XF Huang, American Journal of Physiology–Endocrinology and Metabolism, 2002

Selective antagonist [3H] SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia
– K Zavitsanou, T Garrick, XF Huang, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2004

Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia
– CS Weickert, SJ Fung et al., Molecular Psychiatry, 2013
Xufeng Huang | Neuroscience of Obesity and Schizophrenia | Neuroscience Academic Excellence Award

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