Prof. Chao Han | Postoperative cognitive dysfunction | Best Researcher Award

Prof. Chao Han, Yixing People’s Hospital, China.

Han Chao, a dedicated and accomplished anesthesiologist from Yixing, Jiangsu, China, has made significant contributions to the field of anesthesiology over the course of his career. With a strong academic foundation, including degrees in Clinical Medicine, Surgery, and Anesthesiology, Han Chao has worked at Yixing People’s Hospital for over 19 years, where he has developed expertise in clinical anesthesia and surgical care. His research focuses primarily on the intersection of immunology and anesthesia, specifically studying how preoperative emotional factors like anxiety influence postsurgical pain and exploring the molecular mechanisms behind pain management and immune response during surgery. His work has earned him recognition and funding from notable medical and public health foundations, positioning him as a respected figure in his field.

 

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Early Academic Pursuits 📚

Han Chao’s academic journey has been both extensive and distinguished, beginning with his undergraduate studies in Clinical Medicine at Nanjing Medical University in 1995. His early interest in medicine led him to pursue his bachelor’s degree with dedication, building a strong foundation in medical science. Motivated by a desire to deepen his expertise, he further advanced his studies, earning a Master of Surgery degree from Jiangsu University in 2014. This provided him with a solid understanding of surgical practices, paving the way for his specialized focus in anesthesiology. His commitment to advancing in this field culminated in a Doctor of Anesthesiology degree from Nanjing Medical University in 2019. Throughout his academic career, Han Chao exhibited an exceptional ability to balance both theoretical knowledge and clinical practice, setting the stage for a prolific professional trajectory in anesthesiology.

Professional Endeavors 💼

Since 2000, Han Chao has been an integral member of the Department of Anesthesiology at Yixing People’s Hospital in Jiangsu, where he has dedicated over two decades to the field. His role has involved both patient care and institutional responsibilities, where he has become well-known for his clinical proficiency and thorough understanding of anesthesiology. His expertise in performing anesthesia procedures with precision, along with his commitment to continuous professional development, has made him a key figure in his department. Han Chao’s professional endeavors also extend beyond the operating room, where he is actively involved in the training and mentorship of new medical staff, helping to shape the future of anesthesiology in his community.

Contributions to Research 🧬

One of Han Chao’s most significant contributions to the field of anesthesiology lies in his research, particularly in the areas of immunology and its relationship with surgery. His work has explored the intricate connections between preoperative anxiety, negative emotional reactions, and chronic postsurgical pain. This is encapsulated in his project, “The Effect and Mechanism of Preoperative Anxiety and Other Negative Emotional Reactions on Chronic Postsurgical Pain,” supported by the Wuxi Medical and Public Health Foundation. Through his research, Han Chao aims to identify novel mechanisms that could help improve patient outcomes and address complications related to surgical procedures. His studies into the molecular mechanisms of morphine’s effect on Th2 cells have also shed light on the complex pathways that govern pain and immune responses, which may ultimately lead to better pain management strategies for patients.

Research Focus and Innovation 🔬

Han Chao’s research primarily focuses on immunology in the context of surgery, with an emphasis on how anesthetics and pain management strategies can influence immune responses. His work on morphine’s impact on Th2 cells and the PKC-θ-GATA3 signaling pathway is at the forefront of efforts to understand the broader implications of anesthetic drugs on immune function. This innovative research seeks to bridge the gap between anesthesia and immunology, exploring how anesthesia not only influences the body’s response to surgery but also how it could potentially alter long-term health outcomes. By investigating these underlying mechanisms, Han Chao’s research aims to develop more targeted and effective treatments for patients undergoing surgery, especially those at risk for chronic postsurgical pain.

Accolades and Recognition 🏆

Throughout his career, Han Chao has received considerable recognition for his work in both clinical practice and research. His involvement in groundbreaking research has earned him prestigious funding from several respected foundations, including the Jiangsu Human Resources and Social Security Foundation. His scientific contributions have been widely acknowledged in medical circles, and he has presented his findings at numerous academic conferences. These accolades reflect his standing as an expert in his field and his ongoing commitment to advancing the understanding of anesthesiology. His achievements highlight not only his technical skills in anesthesia but also his ability to contribute to the scientific community through innovative research.

Impact and Influence 🌍

Han Chao’s work in anesthesiology has had a profound impact on his colleagues, patients, and the broader medical community. His influence extends beyond his clinical and research endeavors, as he actively contributes to medical education. As a mentor, he has guided numerous young professionals in the field, sharing his knowledge and experience. His research has the potential to significantly improve patient care, particularly in reducing the risks associated with anesthesia and improving pain management post-surgery. Han Chao’s approach to integrating immunological insights into anesthesiology has opened new avenues for future exploration and has positioned him as a thought leader in his field, influencing both practice and policy.

📚 Publications

  • Effect of Remimazolam-Vs Propofol-Based Intravenous Anesthesia on Surgical Stress Response and Post-Operative Immune Function in Patients with Gastric Radical Surgery
    Authors: Xu, Q., Cheng, X., Sun, H., Wang, C., Han, C.
    Year: 2024

 

  • Development and Validation of a Delirium Risk Prediction Model for Elderly Patients Undergoing Elective Orthopedic Surgery
    Authors: Guo, Y., Ji, H., Liu, J., Ma, T., Han, C.
    Year: 2023

 

  • Effect of Subanesthetic Dose of Esketamine on Perioperative Neurocognitive Disorders in Elderly Undergoing Gastrointestinal Surgery: A Randomized Controlled Trial
    Authors: Han, C., Ji, H., Guo, Y., Ruan, Z., Ma, T.
    Year: 2023

 

  • Intranasal Sufentanil Combined with Intranasal Dexmedetomidine: A Promising Method for Non-Anesthesiologist Sedation During Endoscopic Ultrasonography
    Authors: Wang, Y., Ge, Z.-J., Han, C.
    Year: 2022

 

  • ABCA7 rs3764650 Polymorphism is Associated with Delayed Neurocognitive Recovery
    Authors: Yu, L., Ji, H., Zhou, M., Han, C., Ma, T.
    Year: 2022

 

  • Sodium Bicarbonate Sub-Diaphragmatic Irrigation Relieves Shoulder Pain After Total Laparoscopic Hysterectomy: A Randomized Controlled Trial
    Authors: Liu, L., Xia, T., Ji, H., Han, C., Ma, T.
    Year: 2021

 

  • Dexmedetomidine Directs T Helper Cells Toward Th1 Cell Differentiation via the STAT1-T-Bet Pathway
    Authors: Lei, D., Liu, L., Xie, S., Ma, T., Han, C.
    Year: 2021

 

  • Association Between BDNF rs6265 Polymorphisms and Postoperative Cognitive Dysfunction in Chinese Han Population
    Authors: Xie, S., Yu, L., Zhou, M., Lei, D., Han, C.
    Year: 2020

 

  • Morphine Induces the Differentiation of T Helper Cells to Th2 Effector Cells via the PKC-θ–GATA3 Pathway
    Authors: Han, C., Lei, D., Liu, L., Ma, T., Li, S.
    Year: 2020

 

  • Dexmedetomidine May Reduce IL-6 Level and the Risk of Postoperative Cognitive Dysfunction in Patients After Surgery: A Meta-Analysis
    Authors: Lei, D., Sha, Y., Wen, S., Liu, L., Han, C.
    Year: 2020

Conclusion

Han Chao’s career is a testament to his commitment to advancing both clinical practice and scientific research in anesthesiology. Through his research into the effects of anesthesia on immune responses and pain management, he has paved the way for improved patient care and new approaches to managing surgical outcomes. His contributions to medical education and mentorship have also ensured that his knowledge and expertise continue to shape the future of anesthesiology. As he moves forward, Han Chao is poised to leave a lasting legacy in the medical community, with a focus on improving patient recovery and pioneering new approaches to anesthesia and immunology.

 

Chao Han | Postoperative cognitive dysfunction | Best Researcher Award