Assoc. Prof. Dr. Kaizhi Li, West China Hospital, Sichuan University, China.
Dr. Kaizhi Li is an accomplished Associate Professor at West China Hospital, Sichuan University, with a strong foundation in organic synthesis and catalytic reaction design. From his early academic training at Sichuan University to his impactful postdoctoral work at the National University of Singapore, Dr. Li has consistently contributed to the advancement of asymmetric catalysis and unsaturated bond transformations. Supported by prestigious funding bodies, his research continues to push the boundaries of efficient and sustainable chemical synthesis.
Profile
Orcid
🎓 Early Academic Pursuits
Kaizhi Li’s academic journey began with a passion for organic chemistry, which ultimately led him to pursue advanced studies at Sichuan University. He obtained his Ph.D. in 2016, where his research delved deeply into the challenging yet rewarding field of C(sp³)–H cross-dehydrogenative coupling reactions. This foundational work not only showcased his innovative thinking and mastery of complex molecular transformations but also laid the groundwork for a promising career in synthetic chemistry.
🌏 Professional Endeavors Abroad
Following his doctoral studies, Dr. Li expanded his academic horizons by joining the renowned research group of Professor Yixin Lu at the National University of Singapore. Between 2016 and 2020, he played a pivotal role in advancing asymmetric reactions using organic small molecule catalysts. His international experience helped broaden his perspective, refine his experimental skills, and deepen his understanding of catalytic systems at a global research frontier, making him a valuable contributor to the field.
🔬 Research Focus and Scientific Contributions
Upon returning to China, Dr. Li launched his independent research program at the prestigious West China Hospital of Sichuan University in 2020. His work is primarily centered on the efficient transformation of unsaturated bonds—a crucial area in organic synthesis with wide-ranging applications in pharmaceuticals and materials science. His innovative approaches aim to improve selectivity, sustainability, and functional group tolerance in catalytic reactions, pushing the boundaries of modern synthetic methodologies.
🧪 Breakthrough Projects and Funding Success
Dr. Li’s research excellence has been recognized and supported by significant funding bodies. He is currently leading key projects under the National Natural Science Foundation of China (Grant No. 22201190) and the Department of Science and Technology of Sichuan Province (2023NSFSC1088). These competitive grants underscore his growing influence in the field and his commitment to exploring transformative chemical reactions with real-world impact.
🏅 Accolades and Recognition
Throughout his career, Dr. Li has earned recognition not only for his innovative chemistry but also for his dedication to academic leadership. His achievements in asymmetric catalysis and bond transformation have garnered the respect of peers both nationally and internationally. His ability to bridge fundamental research with applied science continues to earn him a place among the emerging leaders in synthetic organic chemistry.
💡 Impact and Influence in Chemistry
Kaizhi Li’s research contributions have significantly influenced the direction of modern organic synthesis, particularly in sustainable catalytic strategies. His work provides valuable tools for the design of more efficient and selective synthetic pathways. By mentoring students and fostering collaborations, he continues to shape the next generation of chemists, creating a ripple effect that extends far beyond his own laboratory.
🌱 Legacy and Vision for the Future
Looking ahead, Dr. Li envisions expanding his research into new domains of catalysis and reaction design, with an emphasis on environmentally friendly and industrially relevant processes. His long-term goal is to build a world-class research team at Sichuan University that not only advances chemical science but also addresses global challenges in health, sustainability, and materials. His legacy is one of curiosity-driven innovation and a commitment to excellence in both research and mentorship.
Publication
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Title: Three‐Component 1,2‐Methylamidation of Alkynes via Coordinating Activation Strategy
Authors: Jing Ren, Kaiyun Liu, Ning Wang, Jinlong Li, Xinyu Long, Chengming Li, Kaizhi Li
Year: 2025
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Title: Coordinating activation strategy enables 1,2-alkylamidation of alkynes
Authors: Jing Ren, Junhua Xu, Xiangxiang Kong, Jinlong Li, Kaizhi Li
Year: 2023
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Title: Transition-metal-free oxidative annulation reactions between N-acyl-2-aminoacetophenones and alkynes for the facile synthesis of 2-amino-1-naphthols
Authors: Jing Ren, Kaiyun Liu, Xiangxiang Kong, Kaizhi Li
Year: 2023
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Title: Modular Synthesis of α-Aryl-α-Heteroaryl α-Amino Acid Derivatives via a Copper-Catalyzed Cross-Dehydrogenative-Coupling Reaction Using Air as the Sole Oxidant
Authors: Xiangxiang Kong, Jing Ren, Jinlong Li, Yu Liu, Kaizhi Li
Year: 2023
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Title: Copper-Catalyzed 1,2-Difunctionalization Trifluoromethylamidation of Alkynes Assisted by a Coordinating Group
Authors: Jing Ren, Kaiyun Liu, Ning Wang, Xiangxiang Kong, Jinlong Li, Kaizhi Li
Year: 2023
🔚 Conclusion
Dr. Li’s journey reflects a blend of academic excellence, international collaboration, and visionary research. His work not only contributes significantly to the field of synthetic chemistry but also inspires a new generation of scientists. As he continues to innovate and mentor, Dr. Kaizhi Li is poised to leave a lasting legacy in the realm of chemical sciences, both in China and across the global scientific community.