Michael Sacher | Neurodevelopmental Processes | Best Researcher Award

Published on by Neuroscientists

Dr. Michael Sacher | Neurodevelopmental Processes | Best Researcher Award

Dr. Michael Sacher | Concordia University | Canada

Dr. Michael Sacher is a distinguished cell biologist and professor at Concordia University in Montreal, Canada, currently serving as Chair of the Department of Biology. He earned his Ph.D. in Biochemistry from McGill University and has held numerous academic and research positions, including postdoctoral work at Yale University and leadership roles in proteomics research. His work focuses on vesicle trafficking, organelle communication, and the molecular mechanisms regulating intracellular transport, with significant contributions to understanding the TRAPP (Transport Protein Particle) complex and its role in cellular function. Dr. Sacher has authored and co-authored over 180 publications, mentoring students and postdoctoral researchers throughout his career. His research has had substantial impact, reflected in more than 18,000 citations, an h-index of 36, and an i10-index of 53, underscoring his influence in cell biology and molecular genetics. His findings have advanced knowledge of cellular transport mechanisms and their implications for human disease, particularly in disorders linked to vesicle trafficking dysfunction. Through his work, Dr. Sacher continues to shape the fields of cell biology and biochemistry, combining rigorous experimental approaches with innovative imaging and molecular techniques to elucidate complex intracellular processes.

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Featured Publications

  • Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., … (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), 1–382.

  • Sacher, M., Jiang, Y., Barrowman, J., Scarpa, A., Burston, J., Zhang, L., … (1998). TRAPP, a highly conserved novel complex on the cis‐Golgi that mediates vesicle docking and fusion. The EMBO Journal, 17(8), 2494–2503.

  • Sacher, M., Barrowman, J., Wang, W., Horecka, J., Zhang, Y., Pypaert, M., … (2001). TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Molecular Cell, 7(2), 433–442.

  • Guo, W., Sacher, M., Barrowman, J., Ferro-Novick, S., & Novick, P. (2000). Protein complexes in transport vesicle targeting. Trends in Cell Biology, 10(6), 251–255.

  • Wang, W., Sacher, M., & Ferro-Novick, S. (2000). TRAPP stimulates guanine nucleotide exchange on Ypt1p. The Journal of Cell Biology, 151(2), 289–296.