lavanya Choppavarapu | Molecular and Cellular Neuroscience | Research Excellence Award

Dr. lavanya Choppavarapu | Molecular and Cellular Neuroscience | Research Excellence Award

Dr. lavanya Choppavarapu | Medical college of Wisconsin | United States

Lavanya Choppavarapu, Ph.D., is a research scientist specializing in cancer genomics, chromatin biology, and genome-editing technologies. She currently serves at the Medical College of Wisconsin, where she leads projects applying CRISPR-Cas9 approaches to investigate mechanisms of endocrine-resistant breast cancer. Her postdoctoral training at the Medical College of Wisconsin and the University of Texas Health Science Center San Antonio strengthened her expertise in regulatory genomics, particularly in defining the roles of chromatin looping, 3D genome organization, and enhancer–promoter interactions across breast, prostate, and pancreatic cancer models. Earlier, at the National Institute of Mental Health and Neurosciences, she contributed extensively to human genetics research as a Senior and Junior Research Fellow, and further gained foundational experience at the All India Institute of Medical Sciences. Her academic background spans biotechnology and human genetics, providing a multidisciplinary foundation for her cancer-focused investigations. Dr. Choppavarapu has produced impactful scientific contributions, reflected in 189 citations, an h-index of 8, an i10-index of 7, and 132 citation counts with an h-index of 6 and i10-index of 5 across platforms. Her work continues to advance understanding of gene regulation, epigenetic control, and chromatin dynamics in cancer progression.

Profile: Google Scholar

Featured Publications

Lavanya, C., Venkataswamy, M. M., Sibin, M. K., Srinivas Bharath, M. M., Manoj, M. J., & others. (2018). Down regulation of human telomerase reverse transcriptase (hTERT) expression by BIBR1532 in human glioblastoma LN18 cells. Cytotechnology, 70(4), 1143–1154.

Sibin, M. K., Bhat, D. I., Narasingarao, K. V. L., Lavanya, C., & Chetan, G. K. (2015). CDKN2A (p16) mRNA decreased expression is a marker of poor prognosis in malignant high-grade glioma. Tumor Biology, 36(10), 7607–7614.

Li, J., Fang, K., Choppavarapu, L., Yang, K., Yini, X., & others. (2021). Hi-C profiling of cancer spheroids identifies 3D-growth-specific chromatin interactions in breast cancer endocrine resistance. Clinical Epigenetics, 13, Article 175.

Yang, Y., Choppavarapu, L., Fang, K., Naeini, A. S., Nosirov, B., Li, J., Yang, K., & others. (2020). The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells. Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms, 1863(11), 194631.

Lavanya, C., Sibin, M. K., Srinivas Bharath, M. M., Manoj, M. J., & others. (2016). RNA interference mediated downregulation of human telomerase reverse transcriptase (hTERT) in LN18 cells. Cytotechnology, 68(6), 2311–2321.

Sibin, M. K., Bhat, D. I., Lavanya, C., Manoj, M. J., Aakershita, S., & Chetan, G. K. (2014). CDKN2A exon-wise deletion status and novel somatic mutations in Indian glioma patients. Tumor Biology, 35(2), 1467–1472.

Abolghasem Esmaeili | Molecular Neuroscience | Best Researcher Award

Prof. Dr. Abolghasem Esmaeili | Molecular Neuroscience | Best Researcher Award

Prof. Dr. Abolghasem Esmaeili | University of Isfahan | Iran

Dr. Abolghasem Esmaeili is a distinguished neuroscientist and molecular biologist whose career spans veterinary medicine, neuroscience, and advanced molecular research. His academic foundation in veterinary science evolved into a deep specialization in the molecular biology of the brain, with groundbreaking research on GABAA receptor subunits in the amygdala. Over the years, he has contributed significantly to understanding gene expression in the central nervous system, neurodegenerative diseases, and the molecular mechanisms of learning and memory. His scholarly output includes books, translations, and high-impact journal articles, alongside expertise in advanced laboratory techniques such as electrophysiology, molecular cloning, and live-cell imaging. Through teaching, mentorship, and global collaborations, he has strengthened neuroscience research capacity and inspired future scientists.

Academic Profile

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Early Academic Pursuits

Dr. Abolghasem Esmaeili began his academic path in veterinary medicine, completing a doctoral dissertation on embryo transfer in sheep. His passion for understanding brain function led him to pursue a doctoral degree in molecular biology with a specialization in neuroscience. His research focused on the distribution and function of GABAA receptor subunits in the amygdala, providing new insights into the neural mechanisms that shape emotional processing and memory.

Professional Endeavors in Neuroscience

Over the years, Dr. Esmaeili has contributed extensively to neuroscience research and education, holding academic positions at the University of Isfahan. His postdoctoral work at the Queensland Brain Institute strengthened his expertise in electrophysiology and molecular neuroscience, while his time as an academic guest at the University of Zurich expanded his global research collaborations. He continues to lead projects that bridge molecular biology with advanced neurophysiological techniques.

Contributions and Research Focus

Dr. Esmaeili’s research combines advanced laboratory methods such as patch-clamp electrophysiology, confocal microscopy, gene expression analysis, molecular cloning, and live-cell imaging. His work focuses on gene regulation in the central nervous system, particularly in the context of neurodegenerative diseases, and the molecular biology of learning and memory. He also investigates recombinant protein technology and its potential applications in neuroscience.

Scholarly Works 

He has authored significant academic texts, including works on physiology and molecular techniques, and has translated key molecular biology resources. His scientific publications cover diverse topics such as the neuroregenerative effects of nanoparticles, the role of natural compounds in neuronal branching, and the impact of physiological changes on cognitive function. These studies reflect a blend of fundamental research and applied innovation in brain science.

Accolades and Recognition

Dr. Esmaeili’s contributions have been acknowledged through prestigious awards in neuroscience, highlighting his excellence in research and dedication to advancing the understanding of brain function. His recognition underscores the value and impact of his scientific endeavors in both national and international contexts.

Impact and Influence

Through teaching, mentorship, and collaborative projects, Dr. Esmaeili has inspired a generation of students and researchers to explore molecular neuroscience. His efforts have introduced advanced research methodologies to his institution and promoted cross-disciplinary collaboration. His work not only advances academic knowledge but also supports the development of innovative strategies for studying and addressing neurological disorders.

Legacy and Future Contributions

Dr. Esmaeili continues to expand his research into the molecular and cellular mechanisms underlying neurodegenerative diseases. By integrating molecular biology, electrophysiology, and nanotechnology, he aims to develop novel therapeutic approaches while nurturing emerging talent in neuroscience. His career stands as a testament to a lifelong commitment to discovery, innovation, and the advancement of brain science.

Publication

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 …
B Zhou, RM Carrillo-Larco, G Danaei, LM Riley, CJ Paciorek, GA Stevens, … 2021

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based …
A Rodriguez-Martinez, B Zhou, MK Sophiea, J Bentham, CJ Paciorek, … 2020

Iron oxide nanoparticles may damage to the neural tissue through iron accumulation, oxidative stress, and protein aggregation
Z Yarjanli, K Ghaedi, A Esmaeili, S Rahgozar, A Zarrabi 2017

Prediction of GABAA receptor proteins using the concept of Chou’s pseudo-amino acid composition and support vector machine
H Mohabatkar, MM Beigi, A Esmaeili 2011

Crosstalk between obesity, diabetes, and alzheimer’s disease: Introducing quercetin as an effective triple herbal medicine
S Ebrahimpour, M Zakeri, A Esmaeili 2020

Platelet-rich plasma application in chondrogenesis
A Kabiri, E Esfandiari, A Esmaeili, B Hashemibeni, A Pourazar, M Mardani 2014

Using superparamagnetic iron oxide nanoparticles to enhance bioavailability of quercetin in the intact rat brain
R Enteshari Najafabadi, N Kazemipour, A Esmaeili, S Beheshti, S Nazifi 2018

Conclusion

Dr. Esmaeili’s lifelong dedication to neuroscience reflects an exceptional blend of academic rigor, innovative research, and mentorship. His work has advanced the understanding of brain function at the molecular level while opening new possibilities for therapeutic interventions in neurodegenerative diseases. With a legacy rooted in discovery and a vision for future innovation, he continues to shape the global neuroscience landscape and serve as a role model for aspiring researchers.