Dr. Oleksandr Shapoval, Ph.D., is a dedicated scientific researcher at the Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic in Prague, where he contributes to advanced developments in multimodal nanomarkers for complex microbial systems. His work centers on the synthesis, characterization, and functionalization of luminescent and magnetic nanoparticles, along with the design of functional colloids and nanosystems that serve as versatile multimodal imaging probes capable of immobilizing low-molecular-weight bioactive compounds and optimizing nanoparticle compatibility across diverse environments. He holds a Ph.D. in Chemistry with specialization in macromolecular compounds, complemented by degrees in administrative and financial management, as well as extensive training in chemical technology, fuel, and carbon materials. Over his career, Dr. Shapoval has established a strong academic presence, reflected in 136 citations, 17 published documents, and an h-index of 8, demonstrating the impact and quality of his scientific contributions. His multidisciplinary background and sustained research productivity position him as a valuable contributor to the field of nanosystems engineering, bridging chemistry, materials science, and bio-nanotechnology in ways that advance both theoretical understanding and practical application.
Featured Publications
Vasylyshyn, T., Patsula, V., Větvička, D., Shapoval, O., Pankrác, J., Kabešová, M., Beneš, J., & Horák, D. (2025). Intraperitoneal versus intravenous administration of Flamma®-conjugated PEG-alendronate-coated upconversion nanoparticles in a mouse pancreatic cancer model. Nanoscale Advances.
Nahorniak, M., Horák, D., Šlouf, M., Steinhart, M., Shapoval, O., Engstová, H., & Ježek, P. (2025). Lanthanide-based UCNPs: Toxicity evaluation and interaction of ultrasmall core vs. core–shell nanoparticles with cells. Materials Advances.
Vasylyshyn, T., Huntošová, V., Patsula, V., Olejárová, S., Slabý, C., Jurašeková, Z., Bánó, G., Kubacková, J., Šlouf, M., Shapoval, O., et al. (2025). Surface-engineered core–shell upconversion nanoparticles for effective hypericin delivery and multimodal imaging. Nanoscale.
Shapoval, O., Patsula, V., Větvička, D., Šlouf, M., Kabešová, M., Vasylyshyn, T., Svobodová, L. M., Konefal, M., Kočková, O., Pankrác, J., et al. (2025). Theranostic verteporfin-conjugated upconversion nanoparticles for cancer treatment. Nanomaterials, 15(22), 1690.
Shapoval, O., Engstová, H., Šlouf, M., Kočková, O., Dlasková, A., Jabůrek, M., Halili, A., Mozheitová, A., Jirák, D., Ježek, P., et al. (2025). Liraglutide-conjugated poly(methyl vinyl ether-alt-maleic acid)-coated core–shell upconversion nanoparticles for theranostics of diabetes. ACS Applied Materials & Interfaces.