Ms. Deepika Singhal | Neurophysiology | Best Researcher Award
Ms. Deepika Singhal | Medical Faculty Mannheim | Germany
Deepika Singhal is an emerging neurophysiologist whose academic path has been marked by consistent excellence from her early training in biochemistry and biotechnology to her advanced doctoral research in chronic pain mechanisms. Her professional journey spans leading institutions in India, Germany, the United States, and the United Kingdom, where she has gained expertise in molecular biology, neurophysiology, and computational genomics. Her research focuses on uncovering sex differences in stress-induced predisposition to chronic low back pain, combining behavioral models, molecular assays, and bioinformatics approaches. In addition to her scientific achievements, she has demonstrated leadership by managing research teams, securing competitive grants, organizing international symposia, and contributing to peer-reviewed publications.
Profile
Orcid
Early Academic Pursuits
Deepika Singhal began her academic journey with a strong foundation in the life sciences, pursuing studies in biochemistry and medical biotechnology. Her early academic training fostered a deep curiosity about the molecular basis of health and disease. During her master’s studies, she undertook research on genetic and epigenetic alterations in neurotransmitter systems associated with opioid dependence, which provided her with essential skills in molecular biology and an appreciation for the complexity of neurobiological processes. This early immersion in both theoretical knowledge and practical laboratory work laid the groundwork for her future specialization in neurophysiology.
Professional Endeavors
Building upon her academic preparation, Deepika advanced into diverse research roles across India and Germany, contributing to large-scale genomic and molecular studies. She gained valuable experience at leading institutes where she developed expertise in genome-wide association studies and microbiome-based therapeutic workflows. Transitioning to Europe, she joined research programs that expanded her skill set into preclinical pain research and computational biology. As a doctoral candidate in neurophysiology, she has since led independent research projects, managed international collaborations, and supervised junior researchers, blending scientific rigor with leadership and project management.
Contributions and Research Focus
Deepika’s primary research focus lies in understanding the biological underpinnings of chronic pain, with particular emphasis on sex differences in stress-related mechanisms. Her doctoral work investigates how adolescent stress predisposes males and females differently to chronic low back pain in adulthood, combining behavioral assays, molecular analysis, and high-resolution imaging techniques. Her findings have revealed striking differences between latent and manifest sensitization in males and females, linked to microglial priming and gene expression patterns. This work contributes to a growing body of knowledge that seeks to develop sex-specific therapeutic strategies for chronic pain disorders.
Collaborative Engagements
Deepika’s research has been enriched by international collaborations with renowned laboratories in the United States and the United Kingdom. Working with experts in molecular pain research, she has optimized sequencing protocols, developed advanced bioinformatics pipelines, and contributed to manuscripts exploring microglial activation and its modulation. These collaborations highlight her ability to integrate diverse methodologies and perspectives, strengthening the translational potential of her findings.
Accolades and Recognition
Her academic and research achievements have been acknowledged through competitive fellowships, awards, and invitations to leading scientific schools and congresses. She has been recognized for innovative research proposals, successfully secured funding for symposia, and earned fellowships that supported her international training. Her selection as a scholar at the European Pain School reflects her standing in the global scientific community, while leadership roles in academic associations demonstrate her commitment to advancing both her field and the scientific environment around her.
Impact and Influence
Beyond her research contributions, Deepika has actively shaped the academic community through leadership and organizational roles. As a representative in her doctoral program, she has spearheaded student-led initiatives, organized symposia, and created platforms for scientific exchange, ensuring a vibrant research culture. Her experience as a peer reviewer and conference presenter underscores her role in disseminating knowledge and influencing the discourse on pain mechanisms and neurophysiology at large. Her application of machine learning tools to complex biological data reflects a forward-looking approach that bridges experimental and computational neuroscience.
Legacy and Future Contributions
Deepika Singhal’s career reflects a trajectory of academic excellence, innovative research, and dedicated leadership. By addressing the pressing challenge of sex-specific mechanisms in chronic pain, her work not only deepens scientific understanding but also holds the promise of influencing future therapeutic approaches. Her combination of laboratory expertise, computational acumen, and collaborative spirit positions her to continue contributing significantly to neuroscience and pain research. Looking ahead, her endeavors are likely to leave a lasting legacy in both advancing fundamental science and improving clinical perspectives on chronic pain disorders.
Publications
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Title: Sex Differences in the Effects of Early Life Stressors in a Rat Model of Myofascial Low Back Pain
Authors: Deepika Singhal; Lin Li; Wolfgang Greffrath; Rolf‐Detlef Treede
Year: 2025
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Title: Sex differences in functional modulation of microglia by early-life physical stress in a rat model of chronic primary low back pain
Authors: Deepika Singhal; Jonathan R. Husk; Wolfgang Greffrath; Rolf-Detlef Treede
Year: 2025
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Title: Association of Serotonergic Pathway Gene Polymorphisms With Behavioral Parameters in Patients With Opioid Dependence
Authors: Siddharth Sarkar; Renu Singh; Arundhati Sharma; Muzaffar A Pandit; Ranjan Gupta; Deepika Singhal; Raka Jain; Yatan P Balhara
Year: 2021
Conclusion
Through her multidisciplinary expertise and international collaborations, Deepika Singhal has made impactful contributions to the field of neuroscience, particularly in understanding sex-specific mechanisms of chronic pain. Her ability to integrate molecular biology, data science, and preclinical research highlights her innovative approach to addressing complex biomedical challenges. With a record of awards, leadership roles, and peer recognition, she stands as a promising researcher whose future contributions are poised to advance both scientific discovery and clinical understanding in neurophysiology and pain research.