Chahra Chbili | Clinical Neuroscience | Best Researcher Award

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Assist. Prof. Dr. Chahra Chbili | Clinical Neuroscience | Best Researcher Award

Assist. Prof. Dr. Chahra Chbili | University of Sousse | Tunisia

Dr. Chahra Chbili is an Assistant Professor of Pharmacology at the Higher School of Health Sciences and Techniques of Sousse (ESSTSS) and a member of the Research Laboratory of Metabolic Biophysics and Applied Pharmacology (LR/12ES02) at the Faculty of Medicine Ibn El Jazzar of Sousse, Tunisia. Her academic journey spans extensive training in biological sciences, genetics, and medical biotechnology, with a Ph.D. earned with highest honors for her work on the pharmacokinetic and pharmacogenetic study of carbamazepine therapy in epileptic and bipolar patients. Dr. Chbili’s research focuses on pharmacogenetics, pharmacokinetics, and the molecular mechanisms underlying drug efficacy and toxicity. She has contributed significantly to studies exploring the genetic determinants of drug metabolism, including investigations into glutathione-S-transferases in tuberculosis patients with drug-induced hepatotoxicity. Skilled in advanced laboratory techniques such as PCR, FISH, ELISA, and HPLC-MS, she has developed expertise in integrating molecular biology with clinical pharmacology. Dr. Chbili has authored 17 scientific documents, accumulated 138 citations across 123 indexed works, and maintains an h-index of 7, reflecting her impactful contributions to pharmacological and biomedical research in Tunisia and beyond.

Profiles: Scopus | Orcid | Research Gate

Featured Publications

Chbili, C., Mrad, S., Graiet, H., Selmi, M., Maatoug, J., Maoua, M., Abdellaoui, L., Mrizek, N., Nouira, M., Ben Fredj, M., et al. (2024). Randomized, placebo-controlled pilot study investigating the effects of Laurus nobilis tea on lipid profiles and oxidative stress biomarkers in healthy North African volunteers. The North African Journal of Food and Nutrition Research, 8(17), 86–98.

Chbili, C., Fathallah, N., Laadhari, C., Ouni, B., Saguem, S., Ben Fredj, M., Abdelghani, A., Ben Saad, H., & Ben Salem, C. (2022). Glutathione-S-transferase genetic polymorphism and risk of hepatotoxicity to antitubercular drugs in a North-African population: A case-control study. Gene, 808, 146019.

Rebai, A., Chbili, C., Ben Amor, S., Hassine, A., Ben Ammou, S., & Saguem, S. (2021). Effects of glutathione S-transferase M1 and T1 deletions on Parkinson’s disease risk among a North African population. Revue Neurologique, 177(1–2), 93–99.

Chbili, C. (2021, August 22). The effect of Origanum majorana tea on motor and non-motor symptoms in patients with idiopathic Parkinson’s disease: A randomized controlled pilot study. Journal article.

Chbili, C., Maoua, M., Selmi, M., Mrad, S., Khairi, H., Limem, K., Mrizek, N., Saguem, S., & Ben Fredj, M. (2020). Evaluation of daily Laurus nobilis tea consumption on lipid profile biomarkers in healthy volunteers. Journal of the American College of Nutrition, 39(6), 518–526.

Rebai, A., Reçber, T., Nemutlu, E., Chbili, C., Kurbanoglu, S., Kir, S., Ben Amor, S., Özkan, S. A., & Saguem, S. (2020). GC-MS based metabolic profiling of Parkinson’s disease with glutathione S-transferase M1 and T1 polymorphism in Tunisian patients. Combinatorial Chemistry and High Throughput Screening, 23(8), 785–794.

Hongrui Meng | Neurodegenerative disease | Excellence in Research Award

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Prof. Dr. Hongrui Meng | Neurodegenerative disease | Excellence in Research Award

Prof. Dr. Hongrui Meng,  Institute of Neuroscience, Soochow University, China.

Dr. Hongrui Meng is a highly accomplished neuroscientist whose academic path began with a Ph.D. in Behavioural Neuroscience from Hamamatsu University School of Medicine in Japan. He later conducted postdoctoral research in molecular neurobiology and human genetics at Juntendo University, Tokyo. Currently a professor at the Institute of Neuroscience, Soochow University, Dr. Meng leads a research team dedicated to uncovering the molecular and mitochondrial mechanisms underlying Parkinson’s disease and ALS. His work spans high-impact research projects funded by JSPS, NSFC, and other prestigious bodies. In addition to numerous scientific publications, he has contributed to diagnostic innovation through patented miRNA detection methods. His influence extends beyond academia through translational applications such as wearable technologies for Parkinson’s symptom monitoring.

Profile

Orcid

🎓 Early Academic Pursuits

Dr. Hongrui Meng began his distinguished academic journey in the field of neuroscience by earning his Ph.D. in Behavioural Neuroscience from the prestigious Hamamatsu University School of Medicine in Japan. His early education and training laid a strong foundation in experimental neuroscience, with a focus on the behavioral manifestations of neurodegenerative conditions. These formative years not only sharpened his scientific curiosity but also equipped him with the cross-disciplinary expertise to address complex neurological questions.

🧠 Professional Endeavors

Following his doctoral studies, Dr. Meng advanced his specialization through postdoctoral training in molecular neurobiology and human genetics at Juntendo University in Tokyo. There, he immersed himself in high-level research focusing on the genetic underpinnings of neurological disorders. His competence and dedication soon earned him a faculty appointment as an Assistant Professor in the Department of Research for Neurodegenerative Diseases and Dementia. His professional arc reached a significant milestone in 2020 when he was promoted to Full Professor and moved to the Institute of Neuroscience at Soochow University, where he now leads the Laboratory of Molecular Neurology.

🧬 Contributions and Research Focus

Dr. Meng’s scientific contributions center on the molecular mechanisms of Parkinson’s disease and amyotrophic lateral sclerosis (ALS). His research bridges mitochondrial dysfunction, alpha-synuclein aggregation, and neurodegeneration. He has completed pivotal studies supported by the Japan Society for the Promotion of Science and the Takeda Pharmaceutical Foundation, delving into the role of CHCHD2 gene mutations and mitochondrial pathways. His ongoing projects funded by the National Natural Science Foundation of China (NSFC) explore mitochondrial unfolded protein responses (mtUPR), while another innovative project in Suzhou focuses on wearable technology for monitoring Parkinson’s disease symptoms—demonstrating his commitment to translational and patient-centered neuroscience.

🔬 Innovation and Scientific Output

A notable innovator, Dr. Meng has made strides in molecular diagnostic technologies. His work has led to the development of high-throughput RT-qPCR-based methods for detecting primary and precursor miRNAs, contributing to enhanced genetic analysis of neurodegenerative disorders. He holds a patent granted in South Africa and another under process in China, underscoring his role at the intersection of research and technology. Furthermore, his publications in highly regarded journals like Current Issues in Molecular Biology and Cell Communication and Signaling reflect a consistent record of impactful findings that inform both fundamental neuroscience and clinical approaches.

🏅 Accolades and Recognition

Dr. Meng’s ascent in the academic community has been marked by numerous grants, including multiple from the JSPS and NSFC, attesting to the trust placed in his research vision by top funding bodies. While a formal list of awards may be under-documented, his rapid progression from postdoctoral fellow to professor and research team leader in less than a decade speaks volumes about his recognition among peers and institutional leadership. His leadership in multi-disciplinary and international collaborations is an implicit accolade of his scientific reliability and visionary perspective.

🌍 Impact and Influence

Through his groundbreaking work on mitochondrial mechanisms and neurodegeneration, Dr. Meng is helping to reshape current understanding of Parkinson’s disease pathophysiology. His investigations into alpha-synucleinopathy and microglial disruption have provided fresh insights into cellular degeneration and neuroimmune interactions. Beyond academia, his involvement in developing wearable diagnostic tools highlights his drive to impact patient lives directly. As a consultant on neuroprotective treatments such as PD-018/19, he bridges the academic and pharmaceutical worlds to accelerate therapeutic discovery.

🔮 Legacy and Future Contributions

Looking forward, Dr. Meng is poised to be a leading figure in neurogenetic diagnostics and therapeutic innovation. His laboratory at Soochow University serves as an incubator for future discoveries in neurodegenerative disease mechanisms, and his continued work in mitochondrial research promises to inform emerging therapies. With a growing publication record, international patents, and a robust research pipeline, Dr. Meng’s legacy will be one of bridging basic neuroscience with clinical application—paving the way for novel interventions and a better understanding of brain disorders in the molecular era.

Publication

 

  • Title: Dicer Is Involved in Cytotoxicity and Motor Impairment Induced by TBPH Deficiency
    Authors: Xiang Long, Yijie Wang, Hongrui Meng
    Year: 2025

 

  • Title: Transcriptomic analysis of lipid metabolism genes in Alzheimer’s disease: highlighting pathological outcomes and compartmentalized immune status
    Authors: Sun Y., Zhang Y., Jiang M., Long X., Miao Y., Du H., Zhang T., Meng H., Ma X.
    Year: 2024

 

  • Title: CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis
    Authors: Aya Ikeda, Hongrui Meng, Daisuke Taniguchi, Muneyo Mio, Manabu Funayama, Kenya Nishioka, Mari Yoshida, Yuanzhe Li, Hiroyo Yoshino, Tsuyoshi Inoshita et al.
    Year: 2024

 

  • Title: TDP-43 mutations-induced defects in miRNA biogenesis and cytotoxicity by differentially obstructing Dicer activity in Drosophila and in vitro
    Authors: Xiang Long, Mengni Jiang, Yongzhen Miao, Huanhuan Du, Ting Zhang, Zhuoya Ma, Jiao Li, Chunfeng Liu, Hongrui Meng
    Year: 2024

 

  • Title: A Simple Technique to Assay Locomotor Activity in Drosophila
    Authors: Long X., Du H., Jiang M., Meng H.
    Year: 2023

 

  • Title: Functional MHCI deficiency induces ADHD-like symptoms with increased dopamine D1 receptor expression
    Authors: Meng H.-R., Suenaga T., Edamura M., Nakahara D., Murakami G., Fukuda A., Ishida Y.
    Year: 2021

 

  • Title: Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease
    Authors: Imai Y., Hattori N., Inoshita T., Shiba-Fukushima K., Meng H., Hara K.Y., Sawamura N.
    Year: 2019

 

  • Title: Mutations in CHCHD2 cause α-synuclein aggregation
    Authors: Ikeda A., Nishioka K., Takanashi M., Li Y., Mori A., Okuzumi A., Izawa N., Ishikawa K.-I., Funayama M., Imai Y. et al.
    Year: 2019

 

  • Title: Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling
    Authors: Mori A., Hatano T., Koinuma T., Kubo S.-I., Spratt S., Yamashita C., Okuzumi A., Imai Y., Hattori N., Inoshita T. et al.
    Year: 2019

 

  • Title: Twin CHCH proteins, CHCHD2, and CHCHD10: Key molecules of Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementia
    Authors: Imai Y., Hattori N., Meng H., Shiba-Fukushima K.
    Year: 2019

 

🧾 Conclusion

Dr. Hongrui Meng’s career reflects a dynamic blend of academic excellence, molecular research innovation, and translational neuroscience. His scientific endeavors have not only enriched the understanding of neurodegenerative diseases but have also paved the way for novel diagnostic and therapeutic strategies. With a growing portfolio of impactful research, patents, and leadership in neurobiology, Dr. Meng stands out as a driving force in the global fight against neurological disorders. His work promises continued contributions to neuroscience with lasting influence on both scientific knowledge and patient care.

 

Camilla Bellone | Translational Neuroscience | Best Researcher Award

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Assoc. Prof. Dr. Camilla Bellone | Translational Neuroscience | Best Researcher Award

Assoc. Prof. Dr. Camilla Bellone,  University of Geneva, Switzerland.

Dr. Camilla Bellone is a renowned neuroscientist whose academic and research career has been marked by excellence, innovation, and impact. From her foundational training in Italy to her leadership role in Geneva, she has made pioneering contributions to understanding the neural underpinnings of social behavior. Her work bridges basic science and clinical relevance, and she has played a vital role in training, mentorship, and international collaboration within the neuroscience community.

Profile

Google Scholar

 

🎓 Early Academic Pursuits

Dr. Camilla Bellone began her academic journey with a Master’s degree in Pharmacy from the University of Milano in 2000. With a strong foundation in pharmacology and medical chemistry, she pursued her Ph.D. in “Pharmacology, Toxicology, and Medical Chemotherapy” at the same institution, completing it in 2006. Her early education shaped a robust scientific mindset, preparing her for a career at the intersection of neuroscience and pharmacology. These formative years set the tone for her later work on the molecular mechanisms that govern complex behaviors in both healthy and diseased states.

🧪 Professional Endeavors

After her doctoral studies, Dr. Bellone enhanced her research acumen through a postdoctoral fellowship at the University of California, San Francisco (UCSF), gaining international exposure. She later returned to Switzerland, where she served as a scientist under the Ambizione Fellowship at the University of Geneva. Her academic path took a significant leap when she became an Assistant Professor at the University of Lausanne in 2014, followed by a transition to the University of Geneva in 2016. In 2020, she was promoted to Associate Professor in the Department of Basic Neuroscience, where she continues to lead cutting-edge investigations and mentor future neuroscientists.

🧠 Contributions and Research Focus

At the core of Dr. Bellone’s research lies a deep interest in the neurobiological basis of social behavior, with a particular focus on how these processes are disrupted in neuropsychiatric disorders. Her lab explores the synaptic and circuit-level mechanisms that underpin social cognition, often using advanced molecular and behavioral techniques. Her work has provided critical insights into how alterations in neural plasticity and connectivity contribute to diseases such as schizophrenia and autism spectrum disorders. With over 40 peer-reviewed publications in high-impact journals like Nature Neuroscience and Neuron, Dr. Bellone’s research continues to advance the field of behavioral neuroscience.

🏆 Accolades and Recognition

Dr. Bellone’s scientific excellence has been recognized through several prestigious honors. In 2023, she received the EBBS Mid-Career Award and the Leenaards Scientific Prize for her collaborative project on cerebellar stimulation in schizophrenia. Earlier, she was elected to the distinguished FENS-KAVLI Network of Excellence in 2015, highlighting her position among Europe’s most promising neuroscientists. In 2014, she was honored with the Fondation du Prix Pfizer de la Recherche, marking an early milestone in her independent research career.

🌍 Impact and Influence

Beyond her lab, Dr. Bellone has made meaningful contributions to the academic and scientific community. She has delivered over 20 invited lectures at international conferences and institutions, sharing her discoveries with a global audience. As a dedicated mentor, she has guided eight master’s students and seven PhD candidates, nurturing the next generation of neuroscientists. Her commitment extends to active service on academic committees, grant review panels, and editorial boards, reflecting her role as a respected leader in the field.

👩‍🔬 Balancing Science and Life

A champion of work-life integration, Dr. Bellone has managed to thrive professionally while embracing motherhood. She took two career breaks following the birth of her three children, exemplifying resilience and balance in a demanding academic landscape. Her story is an inspiration to young scientists, especially women, striving to build careers in STEM while honoring personal life choices.

🔬 Legacy and Future Contributions

Looking ahead, Dr. Bellone’s work holds promise for transforming our understanding of social dysfunction in mental illness. Her innovative approaches—blending circuit neuroscience, pharmacology, and behavior—position her as a leading voice in the neurobiology of social behavior. With continued support from initiatives like the ERC Consolidator Grant, her research will likely pave the way for novel therapeutic interventions, leaving a lasting legacy in neuroscience and psychiatry.

Publication

  • Title: NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
    Author: P Paoletti, C Bellone, Q Zhou
    Year: 2013

 

  • Title: Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression
    Author: C Bellone, C Lüscher
    Year: 2006

 

  • Title: Rapid bidirectional switching of synaptic NMDA receptors
    Author: C Bellone, RA Nicoll
    Year: 2007

 

  • Title: Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area
    Author: M Mameli, C Bellone, MTC Brown, C Lüscher
    Year: 2011

 

  • Title: In vivo reprogramming of circuit connectivity in postmitotic neocortical neurons
    Author: A De la Rossa, C Bellone, B Golding, I Vitali, J Moss, N Toni, C Lüscher, …
    Year: 2013

 

  • Title: Mechanisms of synaptic depression triggered by metabotropic glutamate receptors
    Author: C Bellone, C Lüscher, M Mameli
    Year: 2008

 

  • Title: Effects of streptozotocin‐diabetes on the hippocampal NMDA receptor complex in rats
    Author: F Gardoni, A Kamal, C Bellone, GJ Biessels, GMJ Ramakers, F Cattabeni, …
    Year: 2002

 

  • Title: Neurons under T cell attack coordinate phagocyte-mediated synaptic stripping
    Author: G Di Liberto, S Pantelyushin, M Kreutzfeldt, N Page, S Musardo, R Coras, …
    Year: 2018

 

  • Title: mGluRs induce a long‐term depression in the ventral tegmental area that involves a switch of the subunit composition of AMPA receptors
    Author: C Bellone, C Lüscher
    Year: 2005

 

  • Title: SHANK3 controls maturation of social reward circuits in the VTA
    Author: S Bariselli, S Tzanoulinou, C Glangetas, C Prévost-Solié, L Pucci, …
    Year: 2016

 

✅ Conclusion

Dr. Bellone’s journey reflects a remarkable blend of scientific curiosity, academic leadership, and personal resilience. As she continues to explore the brain’s most intricate social circuits, her influence will undoubtedly expand across neuroscience, psychiatry, and therapeutic innovation. Her career serves as both a roadmap and an inspiration for emerging scientists navigating the evolving landscape of brain research.