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Baoying Huang | Pathogen Biology | Best Researcher Award

Ms. Baoying Huang,  National Institute for Viral Disease Control and Prevention, China.

Dr. Baoying Huang, a distinguished professor at the Biotech Center for Viral Disease Emergency, China CDC, has over two decades of experience in combating viral diseases. Her expertise lies in vaccine and antiviral drug development for emerging and re-emerging infectious diseases, including COVID-19, monkeypox, and other human coronaviruses.

 

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🎓 Education Experience

2008.09–2011.07: Doctor of Medicine, Pathogen Biology,Biotech Center for Viral Disease Emergency, China CDC.2005.09–2008.07: Master of Biology, Pathogen Biology,Biotech Center for Viral Disease Emergency, China CDC. 2001.09–2005.07: Bachelor of Biology,
Life Science Department, Nan Hua University, China.

👩‍🔬 Professional Experience

2020.07–Present:  Professor, China CD ,Focus: Vaccine and antiviral drug R&D for SARS-CoV-2 and poxvirus diseases, including COVID-19 and monkeypox. Key Role: Participated in COVID-19 Emergency Projects for SARS-CoV-2 variant monitoring in China.2015.07–2020.07:  Associate Professor, China CDC. Focus: Vaccine and antiviral drug R&D for emerging infectious diseases like influenza and coronaviruses (SARS-CoV, MERS-CoV).2015.04–2015.06:  Assistant Professor, China CDC. Global Health Support Program: Worked in Sierra Leone to establish Ebola lab systems, improving public health infrastructure.2011.07–2015.07: Assistant Professor, China CDC. Focus: Pathogenic molecular mechanisms of influenza viruses, pseudo-virus applications, and gene-engineered vaccines. 2005.09–2011.07:  Graduate Researcher, IVDC, China CDC. Specialization: Developing universal influenza vaccines for cross-protection against various strains.

🔬 Research Focus

Baoying Huang’s work is dedicated to:Vaccine Development: COVID-19 vaccines (BBIBP-CorV, mRNA vaccines) and pan-orthopoxvirus solutions.Emerging Diseases: Countermeasures for SARS-CoV-2, monkeypox, and other viral threats.Diagnostics: Whole-genome sequencing and real-time PCR for virus detection and monitoring.Therapeutics: Screening novel antivirals targeting viruses like SARS-CoV-2 and monkeypox.Key achievements include:Leading the development of Sinopharm COVID-19 vaccine, later approved by WHO for Emergency Use Listing.Establishing monitoring systems for SARS-CoV-2 variants and assessing their impact on public health measures. Advancing monkeypox vaccine research and identifying promising antiviral compounds against orthopoxviruses.

📚 Publications

  • Title: Molecular architecture of monkeypox mature virus
    • Authors: Hong, Y., Huang, B., Zhang, J., Tan, W., Li, S.
    • Year: 2024

 

  • Title: Vaccinia virus Tiantan strain blocks host antiviral innate immunity and programmed cell death by disrupting gene expression
    • Authors: Wu, C., Zhang, Z., Li, Z., Deng, Y., Tan, W.
    • Year: 2024

 

  • Title: A clinically used anti-human papilloma virus agent (3-hydroxyphthalic anhydride-modified bovine β-lactoglobulin) has a potential for topical application to prevent sexual transmission of monkeypox virus
    • Authors: Sha, Y., Huang, B., Hua, C., Tan, W., Jiang, S.
    • Year: 2024

 

  • Title: Development of a multiplex real-time PCR assay for the simultaneous detection of mpox virus and orthopoxvirus infections
    • Authors: Fan, Z., Xie, Y., Huang, B., Tan, W., Guo, F.
    • Year: 2024

 

  • Title: Accurate determination of the whole genome sequencing and open reading frames composition of non-replicating Tiantan strain of vaccinia virus based on novel long read sequencing platform
    • Authors: Zhang, Z., Wu, C., Li, H., Huang, B., Tan, W.
    • Year: 2024

 

  • Title: Characterization of whole genomes from recently emerging Mpox cases in several regions of China, 2023
    • Authors: Wu, C., Cui, L., Pan, Y., Wang, Q., Tan, W.
    • Year: 2024

 

  • Title: Intranasal immunization with single-dose vaccine based on recombinant influenza virus H1N1 expressing the extracellular domain of respiratory syncytial virus G protein induces robust immunity and protection in mice
    • Authors: Han, R., Wang, D., Wang, T., Huang, B., Tan, W.
    • Year: 2024

 

  • Title: Rapid identification of full-length genome and tracing variations of monkeypox virus in clinical specimens based on mNGS and amplicon sequencing
    • Authors: Wu, C., A, R., Ye, S., Lu, J., Tan, W.
    • Year: 2024

 

  • Title: Long-lasting humoral and cellular memory immunity to vaccinia virus Tiantan provides pre-existing immunity against mpox virus in Chinese population
    • Authors: Li, M., Guo, Y., Deng, Y., Gao, G.F., Liu, J.
    • Year: 2024

 

  • Title: Identification of the VP37 pocket of monkeypox virus as a promising target for pan-orthopoxvirus inhibitors through virtual screening and antiviral assays
    • Authors: Huo, S., Wu, L., Huang, B., Xu, Z., Tan, W.
    • Year: 2024

 

Conclusion

Dr. Huang’s career exemplifies unwavering dedication to improving public health through innovation in vaccine development, antiviral research, and diagnostic technologies. Her contributions to tackling global health challenges, such as the COVID-19 pandemic and monkeypox outbreaks, have significantly impacted infectious disease prevention and control worldwide. As viruses continue to evolve, her pioneering work remains a cornerstone in safeguarding global health.

 

 

Baoying Huang | Pathogen Biology | Best Researcher Award

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