David Cooper | Brain Death | Best Extension Activity Award

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Dr. David Cooper | Brain Death | Best Extension Activity Award

Dr. David Cooper |  Massachusetts General Hospital | United States

David K. C. Cooper is a globally renowned surgeon-scientist whose career has been defined by groundbreaking contributions to transplantation and xenotransplantation. Trained in London and Cambridge under eminent surgical leaders, he went on to hold major academic and clinical positions in South Africa, the United States, and most recently at Massachusetts General Hospital/Harvard Medical School. His early work advanced heart preservation and donor management, while his later research pioneered the identification of immune barriers in xenotransplantation and strategies for genetic engineering of pigs as organ sources. Over decades, he has authored more than a thousand scientific works, edited major textbooks, mentored generations of scientists, and held leadership roles in international transplantation societies. Widely recognized with fellowships, lectureships, medals, and awards, his influence spans clinical innovation, basic science, mentorship, and global collaboration.

Profile

Scopus

Early Academic Pursuits

David K. C. Cooper began his academic journey in London, where he pursued his medical education at Guy’s Hospital Medical School in the University of London. His formative years in medicine were shaped not only by rigorous clinical training but also by an early exposure to groundbreaking developments in cardiac surgery and transplantation. He trained under some of the most distinguished figures in surgery and medicine, an experience that inspired his lifelong commitment to advancing the field of organ transplantation. His early research culminated in a doctoral degree in which he investigated methods of heart resuscitation and preservation, establishing the scientific foundation for his later contributions to clinical and experimental transplantation sciences.

Professional Endeavors in Surgery and Transplantation

Dr. Cooper’s professional career has spanned continents and decades, encompassing appointments in England, South Africa, the United States, and later at leading institutions in Boston and beyond. In South Africa, at the University of Cape Town and Groote Schuur Hospital, he worked alongside Christiaan Barnard and took responsibility for the heart transplant program, simultaneously developing new methods of donor organ preservation and care. His career further evolved with significant roles in the United States, including his work at the Oklahoma Transplantation Institute, the Massachusetts General Hospital, the University of Pittsburgh, and the University of Alabama at Birmingham. Across these roles, he combined clinical practice with pioneering experimental research, contributing to the foundation of xenotransplantation as a viable field of study.

Contributions and Research Focus

The central theme of Cooper’s scientific journey has been transplantation science, with a particular emphasis on xenotransplantation. He was among the first to identify the key antigen responsible for immune rejection of pig organs by human antibodies, a discovery that opened the door to genetically engineering donor pigs for human transplantation. His work also addressed the physiological changes following brain death in potential donors, which led to the adoption of hormonal replacement therapy that is now applied worldwide. Over the decades, his laboratory has been at the forefront of understanding immune barriers, developing organ preservation systems, and promoting translational strategies that brought xenotransplantation closer to clinical reality. His leadership in NIH-funded projects and collaborations with biotechnology companies has further strengthened the translational bridge between bench and bedside.

Scholarly Contributions and Knowledge Dissemination

An integral part of Cooper’s career has been his role in advancing the body of scientific literature. He has authored and co-authored more than a thousand papers and chapters, as well as multiple authoritative textbooks that remain cornerstones in transplantation and xenotransplantation. His editorial leadership, notably as the Editor-in-Chief of Xenotransplantation, reflects his commitment to shaping academic discourse and guiding scientific progress. In addition to specialist texts, he has also authored books intended for a broader audience, thereby making complex scientific achievements accessible to the general public.

Accolades and Recognition

Cooper’s exceptional contributions have been recognized with prestigious honors from surgical colleges, transplantation societies, and international scientific associations. His awards include lectureships, professorships, and distinguished medals that underscore his impact on transplantation medicine. He has been elected to fellowships in major professional organizations and honored by both academic and clinical bodies for his pioneering role in advancing xenotransplantation research. These accolades reflect not only his groundbreaking discoveries but also his leadership in shaping global transplantation practice and policy.

Impact and Influence on the Scientific Community

Beyond his research achievements, Cooper has left a lasting mark through mentorship and global collaboration. He has trained and guided more than a hundred postgraduate and postdoctoral scholars, many of whom have become leaders in their fields. His extensive invited lectures on five continents have ensured the wide dissemination of knowledge, while his service in professional societies has strengthened the organizational foundations of the transplantation community. His role in establishing and leading the International Xenotransplantation Association reflects his influence in consolidating a global scientific network dedicated to one of medicine’s most challenging frontiers.

Legacy and Future Contributions

David K. C. Cooper’s career represents a bridge between the pioneering heart transplant era of the twentieth century and the emerging field of gene-edited organ xenotransplantation in the twenty-first. His experimental and translational work provided essential groundwork for the first gene-edited pig heart transplant into a human recipient. His enduring legacy lies not only in his scientific achievements but also in his vision of making organ shortage a solvable challenge. As xenotransplantation moves toward clinical application, Cooper’s contributions continue to guide future innovations and inspire the next generation of surgeons and scientists committed to transforming transplantation medicine.

Publications

  • Title: Future Therapy for End-Stage Kidney Failure: Gene-Edited Pig Kidney Xenotransplantation
    Authors: [Author(s) not shown]
    Year: 2025 (Review)

  • Title: International Xenotransplantation Association (IXA) Position Paper on Kidney Xenotransplantation
    Authors: [Author(s) not shown]
    Year: 2025 (Review)

  • Title: Pilot Survey of Attitudes Toward Xenotransplantation Among Nursing Students in London, UK
    Authors: [Author(s) not shown]
    Year: 2025 (Article)

  • Title: Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease
    Authors: [Author(s) not shown]
    Year: 2025 (New England Journal of Medicine, Article)

  • Title: Inhibition of Inflammation by IL-6 Blockade in Xenotransplantation
    Authors: [Author(s) not shown]
    Year: 2025 (Review)

  • Title: Human CD55 Expression and C1 Inhibition Partially Protect Gene-Edited Pig Red Blood Cells From Human Complement-Mediated Hemolysis In Vitro
    Authors: [Author(s) not shown]
    Year: 2025 (Article)

  • Title: Anatomical and Physiological Considerations for Pig Cardiac Xenotransplantation
    Authors: [Author(s) not shown]
    Year: 2025 (Review)

  • Title: Impact of COVID-19 Vaccination and Infection on Anti-Triple-Knockout (TKO) Pig Antibody Production: A Study in Patients With End-Stage Liver Disease and Liver Transplant Recipients
    Authors: [Author(s) not shown]
    Year: 2025 (Article)

  • Title: Is There a Need for an Alternative Source of Red Blood Cells for Clinical Transfusion and Will Gene-Edited Pigs Fulfil That Need?
    Authors: [Author(s) not shown]
    Year: 2025 (Note)

  • Title: Treatment of Presumptive Rejection After Orthotopic Pig-to-Baboon Cardiac Xenotransplantation
    Authors: [Author(s) not shown]
    Year: 2025 (Article)

Conclusion

Dr. Cooper’s lifelong dedication to transplantation science has fundamentally reshaped the prospects of solving the organ shortage crisis through xenotransplantation. His discoveries laid the scientific foundation for the first gene-edited pig heart transplant into a human, a landmark achievement that reflects his enduring vision. Combining clinical excellence, scientific innovation, and academic leadership, he leaves a lasting legacy as both a pioneer and mentor. His career not only bridges past milestones with future possibilities but also ensures that transplantation medicine continues to advance toward transformative solutions for patients worldwide.

Rania Awadi | Developmental Neuroscience | Best Researcher Award

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Dr. Rania Awadi | Developmental Neuroscience | Best Researcher Award

Dr. Rania Awadi |  Higher Institute of Medical Technologies of Tunis | Tunisia

Dr. Rania Awadi is a biophysics and medical imaging researcher whose work centers on cardiac biomechanics and non-invasive diagnostic techniques. With a PhD in biophysics and medical imaging, she has conducted advanced studies on left ventricle biomechanics using finite element modelling and gained international experience through research internships in France and collaborations with leading medical institutions in Tunisia. Her research expertise lies in cardiovascular MRI, image processing, and myocardial strain assessment, particularly in pediatric populations where diagnostic challenges are more pronounced. Among her significant contributions is a study on Duchenne Muscular Dystrophy, where she applied cardiac MRI feature tracking to identify early subclinical myocardial dysfunction without contrast agents, an advancement with meaningful clinical impact.

Profile

Google Scholar

Early Academic Pursuits

From the outset of her academic journey, Dr. Rania Awadi cultivated a strong foundation in biophysics, medical physics, and medical imaging. Her doctoral studies at the Higher Institute of Medical Technologies of Tunis were marked by a deep focus on the biomechanics of the left ventricle, where she applied finite element modelling to explore complex cardiac dynamics. Early research internships at prestigious institutions such as IMT Atlantique in France and Sorbonne University enriched her academic profile, enabling her to refine her expertise in advanced imaging and computational modelling techniques.

Professional Endeavors

Building upon her academic training, Dr. Awadi advanced into professional roles that merged teaching and research. She joined the Higher Institute of Medical Technologies of Tunis as a lecturer in biomechanics, where she has contributed to shaping future professionals in medical physics and imaging. Her work also extended to clinical collaborations, including her involvement with the Principal Military Hospital of Tunis and Monji Ben Hmida Center, emphasizing translational research that bridges scientific innovation with patient care.

Contributions and Research Focus

Dr. Awadi’s contributions to medical science are anchored in cardiovascular imaging and cardiac biomechanics. Her expertise lies in cardiac magnetic resonance imaging, image processing, and computational modelling, with a particular focus on assessing myocardial strain. She has addressed the unique challenges of pediatric populations, where smaller heart sizes, higher heart rates, and variability in strain demand precise methodologies. Her research has sought to make early diagnosis more accessible and reliable, especially in vulnerable groups affected by genetic and muscular disorders.

Pioneering Research on Duchenne Muscular Dystrophy

Among her notable achievements, Dr. Awadi conducted a pioneering study on myocardial strain assessment for early diagnosis of Duchenne Muscular Dystrophy in pediatric patients using cardiac MRI. Through the application of feature tracking techniques, she demonstrated the feasibility of detecting subclinical myocardial dysfunction without the use of contrast agents, reducing risks in younger patients. Her findings, published in Applied Sciences, underscored significant associations between myocardial strain parameters and structural cardiac changes, providing a non-invasive tool for monitoring disease progression in affected children.

Accolades and Recognition

Dr. Awadi’s scholarly contributions have been recognized in the international research community through publication in high-impact journals. Her work in Applied Sciences has strengthened her standing as an emerging researcher in cardiac imaging and biomechanics. Her collaborations with European and Tunisian research institutions reflect her growing reputation as a scientist capable of fostering cross-border innovation in medical imaging and biomechanics.

Impact and Influence

The impact of Dr. Awadi’s research extends beyond academic recognition to meaningful influence on clinical practices. By offering new insights into myocardial strain assessment, she has contributed to refining diagnostic approaches for conditions like Duchenne Muscular Dystrophy, where early intervention can significantly alter outcomes. Her teaching and mentorship also shape a new generation of researchers and clinicians, further amplifying the reach of her work across academia and healthcare.

Legacy and Future Contributions

Looking ahead, Dr. Awadi’s career continues to chart a path of scientific advancement and clinical relevance. With expertise spanning biomechanics, MRI, and computational modelling, she is poised to deepen investigations into cardiac function across diverse patient populations. Her future contributions are expected to expand the frontiers of non-invasive diagnostics, ensuring that her legacy in cardiovascular biomechanics and imaging is defined by both innovation and tangible impact on patient health.

Publications

Numerical study of two microwave antennas dedicated to superficial cancer hyperthermia
N. Benameur, R. Awadi, A. Bouabidi, M.A. Mohammed, M.U. Rehman, … – 2024

A quasi-static biomechanical model of the human myocardium based on Cardiac Magnetic Resonance images
R. Awadi, N. Benameur, T. Kraiem, L. Salam – 2023

Comparison of Left Ventricle Deformation Analysis Using Abaqus and CVi42 Software: Insights from Healthy Subjects and patients with Myocardial Infarction
R. Awadi, N. Benameur, A. Sleimi, L. Salam – 2025

Myocardial Strain Assessment for Early Duchenne Muscular Dystrophy Diagnosis in Pediatric Patients Using Cardiac MRI
R. Awadi, N. Benameur, H. Hafsi, T.B. Younes, Y. Arous, S. Labidi, … – 2024

Left Ventricle Wall Motion Abnormalities Detection in Cardiac MRI
N. Benameur, R. Awadi, R. Mahmoudi, M. Deriche, M. Al Betar – 2023

Finite Element of Biomechanical Model of the Human Myocardium from a Cardiac MRI Images
A. Rania, N. Benameur, T. Kraiem, S. Labidi – 2022

of the Human Myocardium from a Cardiac MRI Images
A. Rania, N. Benameur, T. Kraiem, S. Labidi – 2022

Conclusion

Dr. Awadi’s career reflects a blend of academic rigor, professional dedication, and innovative research that addresses pressing clinical needs in pediatric cardiology. Her work has advanced the understanding of myocardial strain assessment, offering tools that improve early diagnosis and patient care. Through her teaching, collaborations, and published research, she has established herself as a promising figure in cardiac imaging and biomechanics. Looking forward, her contributions are set to further bridge the gap between research and clinical application, reinforcing her role as a driving force in the development of non-invasive diagnostic technologies.

Patrick Vermersch | Multiple sclerosis | Best Researcher Award

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Prof. Patrick Vermersch | Multiple Sclerosis | Best Researcher Award

Prof. Patrick Vermersch |  University of Lille |  France

Patrick Vermersch is a distinguished neurologist and academic leader whose career has been defined by groundbreaking contributions to the study and treatment of neurodegenerative diseases, particularly multiple sclerosis and Parkinson’s disease. His early academic research into Tau protein pathology opened new perspectives on Alzheimer’s and related conditions, while his later work at the University of Lille shaped innovative approaches to multiple sclerosis care through specialized units, biomarker research, and pioneering clinical trials. As Director of the Graduate School for Biology and Health, and through his leadership roles in international foundations, he has strengthened global collaboration, fostered next-generation researchers, and promoted patient-centered approaches to care.

Profiles

Orcid 
Scopus

Early Academic Pursuits

Patrick Vermersch began his academic journey deeply fascinated by the complexities of neurodegenerative diseases, directing much of his early research toward Alzheimer’s disease and related conditions. His work in the 1990s, alongside André Delacourte’s team, centered on the phosphorylation of Tau proteins, uncovering disease-specific patterns in conditions such as progressive supranuclear palsy and myotonic dystrophy. This pioneering exploration into Tau pathology not only shed light on abnormal protein distribution in aging but also led to the unexpected discovery of phosphorylated Tau proteins in the cortex of patients with Parkinson’s disease. These formative years established his scientific foundation and positioned him at the forefront of neurobiology research.

Professional Endeavors

At the University of Lille, Patrick Vermersch played a transformative role in expanding both research and clinical care in neurology. Early collaborations with experts in immunology, neuroradiology, and neurology fueled the establishment of a specialized care unit dedicated to patients with multiple sclerosis. His trajectory within the university evolved beyond laboratory work, encompassing administrative and academic leadership positions such as Vice-Dean for Research and Vice-President for Research in Biology and Health. Today, as Director of the Graduate School for Biology and Health, he continues to shape scientific progress by fostering innovation, mentoring students, and advancing institutional research strategies.

Contributions and Research Focus

Patrick Vermersch has been instrumental in multiple sclerosis research, making significant contributions to biomarkers, neuroinflammation, and disease-modifying treatments. His investigations into humoral immunity changes during the early phases of the disease marked an important breakthrough in understanding disease mechanisms. Over time, his research expanded toward treatment development, from symptomatic approaches to disease-modifying therapies. Currently, his work explores novel therapies such as Bruton’s Tyrosine Kinase inhibitors, masitinib, and CAR-T cell therapies, aiming to offer more personalized and effective treatment strategies for patients with progressive forms of multiple sclerosis. Parallel to this, his efforts extend to improving care for Parkinson’s disease, highlighting his broad commitment to advancing neurology.

Advancing Patient-Centered Research

A defining element of his career is the emphasis on patient-centered care. Through the creation of networks such as the Group for the Care and Study of Multiple Sclerosis, which later evolved into the PARCSeP network, Patrick Vermersch revolutionized the way patients are managed in northern France. By integrating multidisciplinary approaches and focusing on the global and multidimensional needs of patients, this initiative significantly improved treatment strategies and outcomes for individuals with both multiple sclerosis and Parkinson’s disease. His focus on patient-related outcomes continues to guide his research, emphasizing the personalization of treatment pathways through prognostic markers and early intensive therapies.

Accolades and Recognition

Patrick Vermersch’s influence extends far beyond his home institution. He has served as a board member of the European Charcot Foundation and co-founded the ParadigMS Foundation, both of which advance international collaboration in neurology research and education. His leadership within these organizations underscores his reputation as a respected authority in multiple sclerosis research and his ability to connect global expertise for collective progress. His recognition in the field reflects not only his scientific contributions but also his commitment to fostering collaboration and knowledge exchange.

Impact and Influence

The breadth of Patrick Vermersch’s work has left a profound mark on both the scientific community and patient care. From foundational discoveries in Tau protein pathology to clinical trial leadership on cutting-edge therapies for multiple sclerosis, his contributions have transformed the understanding and management of neurological diseases. His dedication to optimizing symptomatic treatment strategies, particularly in addressing fatigue and urinary disturbances, demonstrates his responsiveness to patient needs. By blending rigorous scientific research with a compassionate approach to healthcare, he has influenced both academic medicine and everyday clinical practice.

Legacy and Future Contributions

Looking ahead, Patrick Vermersch continues to drive innovation in neurology through his focus on precision medicine. The integration of early biomarkers, prognostic tools, and novel therapies promises to reshape how multiple sclerosis is diagnosed and treated. Ongoing clinical trials exploring therapies such as tolebrutinib and frexalimab signal a promising future for patients with progressive disease forms. His legacy lies not only in the scientific advancements he has spearheaded but also in the model of patient-centered care he has championed. As a mentor, researcher, and leader, he has laid a robust foundation that will continue to inspire future generations of neurologists and researchers dedicated to advancing human health.

Publications

Inhibiting CD40 Ligand in Multiple Sclerosis: A Review of Emerging Therapeutic Potential
Authors: Not specified
Year: 2025

Serum Alpha-Linolenic Acid and Long-Term Multiple Sclerosis Activity and Progression
Authors: Not specified
Year: 2025

Beyond the switch to the biosimilar of natalizumab: What is the impact of changing the JCV test?
Authors: Not specified
Year: 2025

Impact of Natalizumab on Productivity and Ability to Work in Patients with Multiple Sclerosis in France: The TITAN Study
Authors: Not specified
Year: 2025

Long-Term Management and Therapeutic Sequencing for Patients with Relapsing Multiple Sclerosis in France: A Vignette Study
Authors: Not specified
Year: 2025

Tolebrutinib in Nonrelapsing Secondary Progressive Multiple Sclerosis
Authors: Not specified
Year: 2025

Tyrosine kinase inhibitor, masitinib, limits neuronal damage, as measured by serum neurofilament light chain concentration in a model of neuroimmune-driven neurodegenerative disease
Authors: Not specified
Year: 2025

LymphoTEC: a Retrospective Real-World Study on Lymphocyte Reconstitution After Lymphopenia in Patients with Multiple Sclerosis Treated with Dimethyl Fumarate in France
Authors: Not specified
Year: 2025

Generics, Biosimilars and Follow-On Non-Biologic Complex Drugs for Multiple Sclerosis: A Narrative Review of the Regulatory and Clinical Implications for European Neurologists
Authors: Not specified
Year: 2025

Effect of siponimod on retinal thickness, a marker of neurodegeneration, in participants with SPMS: Findings from the EXPAND OCT substudy
Authors: Not specified
Year: 2025

Conclusion

Patrick Vermersch’s legacy lies at the intersection of scientific discovery, clinical innovation, and patient advocacy. His dedication to integrating research with real-world patient outcomes has not only advanced the understanding of neurodegenerative diseases but also transformed treatment paradigms to be more personalized and effective. With ongoing research into Bruton’s Tyrosine Kinase inhibitors, masitinib, and CAR-T cell therapies, his work continues to shape the future of neurology. His vision ensures that advances in science are consistently aligned with improving patient lives, making him a true trailblazer in modern neurological research and care.

Huiyan Li | Neuro-oncology | Best Researcher Award

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Dr. Huiyan Li | Neuro-oncology | Best Researcher Award

Dr. Huiyan Li |  Fudan University | China

Huiyan Li, Ph.D., is a dedicated researcher whose academic journey spans pharmacy, biomedical engineering, tumor biology, and nanomedicine. Her doctoral studies focused on unraveling tumor resistance mechanisms and advancing biomarker detection technologies, while her postdoctoral work has pioneered the use of nanomedicine for cancer therapy, particularly in glioma treatment. She has made significant strides in understanding neurovascular and neuroimmune interactions in brain tumors, contributing to the development of nanoparticle-based therapies. In addition, her leadership in biomedical imaging has enhanced preclinical cancer research and facilitated the application of advanced imaging technologies. Li’s interdisciplinary expertise positions her at the forefront of translational oncology research, bridging fundamental science with innovative therapeutic strategies.

Profile

Google Scholar

Early Academic Pursuits

From the outset of her academic journey, Huiyan Li cultivated a deep interest in the intersection of pharmacy, biomedical engineering, and tumor biology. Her undergraduate studies in pharmacy provided a solid grounding in drug formulation and absorption mechanisms, which she later expanded through her master’s research in biomedical engineering. There, she explored innovative tissue engineering strategies, focusing on nano-polymer-based therapeutics for vascular repair in ischemic tissues. This multidisciplinary foundation prepared her to pursue advanced research in medical sciences, where her doctoral work centered on tumor biology, resistance mechanisms, and biomarker detection.

Doctoral Research in Tumor Biology

During her doctoral training at a leading medical institution, Li concentrated on unraveling the biological mechanisms underlying drug resistance in tumors. She explored the complex signaling pathways, with a particular emphasis on Hedgehog-mediated resistance in tumor models. Alongside these mechanistic studies, she pioneered the development of a novel aptasensor-based assay capable of highly sensitive detection of tumor biomarkers. This innovative work not only provided insights into therapeutic resistance but also advanced precision diagnostics in oncology.

Advancements in Nanomedicine

Following her doctoral studies, Li expanded her expertise into the field of nanomedicine, dedicating her postdoctoral research to the development of iron- and ferritin-based nanomedicines. Her investigations revealed how nanomedicines could exploit biological processes such as organelle cross-talk and oxidative stress to induce tumor cell apoptosis. She also explored strategies to disrupt compensatory mechanisms between selenoproteins, enhancing the therapeutic potential of nanomedicine platforms. These findings have contributed significantly to the broader field of nanobiomedicine, establishing new avenues for tumor-targeted therapy.

Research in Neuro-oncology

Building upon her prior expertise, Li directed her attention to the challenging domain of neuro-oncology. She investigated the mechanisms by which nanoparticles penetrate gliomas and other central nervous system tumors, with a focus on identifying endothelial cell subpopulations that regulate nanoparticle entry. Her work also examined the communication between tumor-associated endothelial cells and immune cells, shedding light on neurovascular and neuroimmune interactions in glioblastoma. This pioneering research represents an important step toward improving nanoparticle-based therapies for brain tumors, which remain among the most difficult cancers to treat.

Contributions to Imaging and Biomedical Technologies

Alongside her research in tumor biology and nanomedicine, Li made significant contributions to biomedical imaging. Serving as a technical director for a small animal live imaging core facility, she became proficient in advanced modalities such as live optical and MicroCT imaging. She applied these tools to monitor tumor development and therapeutic responses in vivo, thereby enhancing preclinical models of neuro-oncology. Her commitment to training and knowledge-sharing ensured that imaging technologies could be widely utilized to accelerate translational cancer research.

Recognition and Emerging Influence

Throughout her career, Li’s dedication to bridging basic science with clinical application has earned recognition within the scientific community. Her cross-disciplinary expertise—spanning pharmacy, biomedical engineering, tumor biology, nanomedicine, and neuro-oncology—has positioned her as an emerging leader in the development of precision therapies for cancer. By integrating advanced imaging, molecular biology, and nanotechnology, she has established a reputation for innovation in the fight against treatment resistance and tumor progression.

Legacy and Future Contributions

Looking ahead, Li’s research promises to make a lasting impact on the fields of nanomedicine and neuro-oncology. Her work is poised to redefine how nanoparticle platforms can be tailored to overcome barriers in the central nervous system, offering new hope for patients with glioblastoma and other brain tumors. By combining mechanistic insights with translational strategies, she is advancing toward a future where cancer therapy becomes more effective, targeted, and personalized. Her legacy will be one of integrating science and technology to push the boundaries of cancer treatment and improve patient outcomes worldwide.

Publications

A forward vision for chemodynamic therapy: issues and opportunities
P Zhao, H Li, W Bu — 2023

Advances in detection of infectious agents by aptamer-based technologies
HY Li, WN Jia, XY Li, L Zhang, C Liu, J Wu — 2020

Immunotherapy for advanced hepatocellular carcinoma, where are we?
L Zhang, J Ding, HY Li, ZH Wang, J Wu — 2020

Folate-conjugated and pH-responsive polymeric micelles for target-cell-specific anticancer drug delivery
J Guan, ZQ Zhou, MH Chen, HY Li, DN Tong, J Yang, J Yao, ZY Zhang — 2017

ZIF‐based nanoparticles combine X‐ray‐induced nitrosative stress with autophagy management for hypoxic prostate cancer therapy
Y Li, T Gong, H Gao, Y Chen, H Li, P Zhao, Y Jiang, K Wang, Y Wu, … — 2021

Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy
B Gong, Y Shen, H Li, X Li, X Huan, J Zhou, Y Chen, J Wu, W Li — 2021

Heterostructures with built‐in electric fields for long‐lasting chemodynamic therapy
H Zhang, Y Chen, W Hua, W Gu, H Zhuang, H Li, X Jiang, Y Mao, Y Liu, … — 2023

Hedgehog signaling, a critical pathway governing the development and progression of hepatocellular carcinoma
J Ding, HY Li, L Zhang, Y Zhou, J Wu — 2021

Polyamine-activated carbonyl stress strategy for oxidative damage therapy
K Wang, J Li, Y Yi, B Lv, Y Wu, C Wang, H Li, Y Li, Y Liu, X Cai, X Meng, … — 2022

Hedgehog signalling mediates drug resistance through targeting TAP1 in hepatocellular carcinoma
XT Zhou, J Ding, HY Li, JL Zuo, SY Ge, HL Jia, J Wu — 2020

Blocking spatiotemporal crosstalk between subcellular organelles for enhancing anticancer therapy with nanointercepters
H Li, H Zhang, X He, P Zhao, T Wu, J Xiahou, Y Wu, Y Liu, Y Chen, … — 2023

Nutrient-delivery and metabolism reactivation therapy for melanoma
Y Chen, C Wang, Y Wu, Y Wang, Y Meng, F Wu, H Zhang, YY Cheng, … — 2024

Novel aptasensor-based assay of sonic hedgehog ligand for detection of portal vein invasion of hepatocellular carcinoma
HY Li, FF Yin, XY Li, WN Jia, J Ding, L Zhang, ZH Wang, QQ Hu, JL Zuo, … — 2021

Conclusion

Through her integration of nanomedicine, neuro-oncology, and advanced imaging, Huiyan Li has established herself as an emerging leader in cancer research. Her contributions address some of the most complex challenges in oncology, particularly treatment resistance and central nervous system tumor targeting. With her innovative approach and commitment to translational impact, she is poised to shape the future of precision medicine in neuro-oncology. Her work stands as a testament to the transformative potential of interdisciplinary research in advancing cancer therapy and improving patient outcomes.

Jing Sui | Neuroimaging | Best Researcher Award

Published on by Neuroscientists

Prof. Jing Sui | Neuroimaging | Best Researcher Award 

Prof. Jing Sui | Beijing Normal University | China

Professor Jing Sui has established herself as a pioneering figure in computational psychiatry and cognitive neuroscience. With a strong foundation in optical engineering, image processing, and computer science, she built her career across leading institutions in the United States and China. Her research contributions lie at the forefront of multimodal fusion, brain imaging data mining, and the application of machine learning and deep learning to mental health studies. By developing innovative methods for biomarker identification, she has advanced diagnostic precision in psychiatry and neurological research. Recognized internationally through numerous awards, top citations, and global rankings, she has played a vital role in shaping both research and mentorship within the field.

Profile

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Early Academic Pursuits

From the beginning of her academic journey, Jing Sui demonstrated a strong aptitude for both engineering and computational sciences. She trained in optical technology and photoelectric instrumentation, while also developing parallel expertise in computer science. Her doctoral work in optical engineering, with a focus on image and signal processing, laid the foundation for her lifelong interest in extracting meaningful patterns from complex brain data. This multidisciplinary background positioned her uniquely at the intersection of neuroscience, engineering, and data science.

Professional Endeavors

Her professional career has spanned leading institutions in both China and the United States. She began as a postdoctoral fellow and later advanced to research scientist and assistant professor at a pioneering brain research network in the United States. Returning to China, she took on leadership roles at the Chinese Academy of Sciences, where she established herself as a principal investigator. Later, she became a professor at prominent national universities, where she continues to mentor and guide future generations of neuroscientists. These roles have enabled her to bridge international research collaborations and foster innovation in computational psychiatry.

Contributions to Cognitive Neuroscience

At the core of her scientific contributions lies the use of advanced data-driven methods to better understand the human brain. She has made notable advances in multimodal fusion techniques, combining diverse forms of neuroimaging data to capture a more holistic view of brain function. Her work integrates signal processing, independent component analysis, and deep learning to uncover hidden patterns that inform the study of mental disorders. By pushing the boundaries of machine learning and multivariate modeling, she has contributed significantly to the field of brain imaging data mining and its translation into clinical research.

Research Focus in Computational Psychiatry

Her research is strongly anchored in the identification of biomarkers for mental health conditions. By applying artificial intelligence to large-scale imaging datasets, she has advanced methods for detecting subtle brain alterations linked to psychiatric and neurological disorders. This approach has enhanced the precision of diagnostic tools and informed the development of computational psychiatry as a discipline. Her work illustrates how brain-inspired intelligence can merge with clinical practice to improve patient outcomes, offering pathways toward personalized mental health care.

Accolades and Recognition

Her groundbreaking contributions have been recognized nationally and internationally. She has received top-tier awards for natural sciences, science and technology innovation, and contributions to cancer-related brain imaging research. Prestigious foundations have supported her as a leading young scientist, while multiple academic societies have acknowledged her excellence through best paper awards, top-cited distinctions, and conference recognitions. She has also been consistently ranked among the world’s leading neuroscientists, reinforcing her reputation as a trailblazer in computational psychiatry and neuroimaging.

Impact and Influence

Her influence extends beyond her own discoveries to shaping the global research community. As a mentor and leader, she has cultivated young researchers who continue to expand the field of cognitive neuroscience. She has been instrumental in bringing together expertise from imaging, engineering, and psychiatry, creating an integrative approach that strengthens interdisciplinary collaboration. Her pioneering methods are widely adopted by neuroscientists worldwide, serving as a benchmark for brain imaging and machine learning studies.

Legacy and Future Contributions

The legacy of her work lies in redefining how brain imaging data can be harnessed to advance mental health research. By blending computational innovation with clinical relevance, she has carved a path that others continue to follow. Looking ahead, her contributions are likely to further transform computational psychiatry, particularly as advances in artificial intelligence deepen. Her future work will continue to shape the next generation of neuroscientific discovery, offering new insights into the biological basis of mental health and paving the way for more effective interventions.

Publications

Single subject prediction of brain disorders in neuroimaging: Promises and pitfalls – MR Arbabshirani, S Plis, J Sui, VD Calhoun – 2017

Multimodal fusion of brain imaging data: a key to finding the missing link (s) in complex mental illness – VD Calhoun, J Sui – 2016

A review of multivariate methods for multimodal fusion of brain imaging data – J Sui, T Adali, Q Yu, J Chen, VD Calhoun – 2012

Machine learning in major depression: From classification to treatment outcome prediction – S Gao, VD Calhoun, J Sui – 2018

NeuroMark: An automated and adaptive ICA based pipeline to identify reproducible fMRI markers of brain disorders – Y Du, Z Fu, J Sui, S Gao, Y Xing, D Lin, M Salman, A Abrol, MA Rahaman, … – 2020

Neuroimaging-based individualized prediction of cognition and behavior for mental disorders and health: methods and promises – J Sui, R Jiang, J Bustillo, V Calhoun – 2020

Exploring the psychosis functional connectome: aberrant intrinsic networks in schizophrenia and bipolar disorder – VD Calhoun, J Sui, K Kiehl, J Turner, E Allen, G Pearlson – 2012

Discriminating schizophrenia and bipolar disorder by fusing fMRI and DTI in a multimodal CCA+ joint ICA model – J Sui, G Pearlson, A Caprihan, T Adali, KA Kiehl, J Liu, J Yamamoto, … – 2011

Assessing dynamic brain graphs of time-varying connectivity in fMRI data: application to healthy controls and patients with schizophrenia – Q Yu, EB Erhardt, J Sui, Y Du, H He, D Hjelm, MS Cetin, S Rachakonda, … – 2015

A hybrid machine learning method for fusing fMRI and genetic data: combining both improves classification of schizophrenia – H Yang, J Liu, J Sui, G Pearlson, VD Calhoun – 2010

Interaction among subsystems within default mode network diminished in schizophrenia patients: a dynamic connectivity approach – Y Du, GD Pearlson, Q Yu, H He, D Lin, J Sui, L Wu, VD Calhoun – 2016

Function–structure associations of the brain: evidence from multimodal connectivity and covariance studies – J Sui, R Huster, Q Yu, JM Segall, VD Calhoun – 2014

Distinct and common aspects of physical and psychological self-representation in the brain: A meta-analysis of self-bias in facial and self-referential judgements – C Hu, X Di, SB Eickhoff, M Zhang, K Peng, H Guo, J Sui – 2016

Conclusion

Professor Jing Sui’s work demonstrates the transformative power of combining engineering, neuroscience, and artificial intelligence in understanding the human brain. Her contributions have not only advanced computational psychiatry but also created pathways for practical clinical applications. Through her leadership, mentorship, and groundbreaking research, she has left an enduring impact on global neuroscience. Her continued efforts are poised to deepen the integration of brain-inspired intelligence with mental health care, ensuring her legacy as a leading innovator in the field.

Watit Sontising | Neuroscience | Best Researcher Award

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Dr. Watit Sontising | Neuroscience | Best Researcher Award

Dr. Watit Sontising | Icahn school of medicine at mount sinai | United States

Dr. Watit Sontising is a distinguished chemist whose career seamlessly integrates academic scholarship, industrial innovation, and biomedical research. With a foundation built through advanced studies in chemistry, his expertise spans computational modeling, analytical method development, and environmental compliance. His academic contributions include years of teaching and mentoring in general chemistry, fostering critical thinking and practical skills among diverse student groups. Professionally, he has advanced laboratory efficiency in environmental and industrial chemistry while later transitioning into biotechnology and biomedical research. His current postdoctoral work at the Icahn School of Medicine at Mount Sinai exemplifies his interdisciplinary impact, where he pioneers mass spectrometry imaging and metabolomic profiling to explore neurological disorders. Through a robust portfolio of publications and methodological innovations, he has significantly contributed to the fields of crystallography, material science, and spatial metabolomics.

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Early Academic Pursuits

Dr. Watit Sontising began his academic journey in chemistry with a strong foundation developed during his undergraduate studies in Thailand. His early exposure to chemical sciences sparked a curiosity for understanding molecular interactions and their implications in both natural and applied systems. Pursuing graduate studies in the United States, he advanced his expertise through master’s and doctoral programs in chemistry at the University of California, Riverside. During this time, he immersed himself in research on molecular interactions, computational chemistry, and crystallography, laying the groundwork for a career that bridges theory, experimentation, and application.

Professional Endeavors

His professional trajectory reflects a balance between academia and industry, allowing him to refine skills across diverse environments. At California State University, Fullerton, and later at the University of California, Riverside, he served as a teaching assistant in general chemistry, where he engaged directly with undergraduate students through lectures, laboratory instruction, and mentorship. Following his doctoral studies, he contributed to environmental chemistry as a laboratory manager, spearheading compliance-driven analytical methods, and later transitioned into the biotechnology sector as a research scientist, applying analytical and modeling techniques to sustainable material development. His current role as a postdoctoral fellow in neurology at the Icahn School of Medicine at Mount Sinai demonstrates his interdisciplinary adaptability, integrating chemistry with neuroscience to advance biomedical research.

Contributions and Research Focus

Dr. Sontising’s research has spanned computational chemistry, analytical method development, and biomedical applications. His doctoral work contributed to the understanding of crystal structures, intermolecular forces, and novel phases of elemental and molecular systems. In industry, he developed high-throughput analytical methods that accelerated workflows and improved efficiency in biomaterial research. At Mount Sinai, his focus has shifted toward metabolomics, lipidomics, and mass spectrometry imaging, where he is developing novel methods to study the chemical architecture of the brain. By combining advanced instrumentation with computational pipelines in R and Python, he has been able to elucidate metabolic pathways in neurological disease models, reinforcing the role of chemistry in unraveling complex biological processes.

Scholarly Publications

His contributions to the scientific community are reflected in a body of published work spanning computational chemistry, crystallography, photomechanical materials, polymerization mechanisms, and spatial metabolomics. His publications in journals such as Chemical Science, CrystEngComm, and Physical Review Materials highlight his ability to merge theoretical approaches with practical applications. Recent work in spatial metabolomics protocols has further expanded the methodological toolkit available to researchers studying brain metabolism, representing a bridge between chemical sciences and medical research.

Accolades and Recognition

Throughout his academic and professional career, Dr. Sontising has been recognized for his commitment to both research excellence and teaching impact. His role as a mentor, educator, and scientific contributor has been acknowledged through opportunities to supervise students, lead laboratory teams, and co-author impactful studies. His ability to secure and contribute to grant-funded projects demonstrates not only trust in his expertise but also recognition of his potential to shape innovative research directions.

Impact and Influence

The impact of his work can be seen in multiple spheres—students he has mentored, laboratories he has organized and modernized, and scientific knowledge he has advanced through publications and method development. By linking fundamental chemistry with applied biomedical research, Dr. Sontising has influenced how metabolomics and mass spectrometry are utilized in the study of neurological disorders. His interdisciplinary perspective allows for meaningful collaborations across chemistry, biology, and medicine, creating pathways for innovation that resonate beyond a single discipline.

Legacy and Future Contributions

Looking forward, Dr. Sontising is positioned to make lasting contributions at the intersection of chemistry and neuroscience. His ongoing development of novel imaging and analytical methods will continue to expand the understanding of brain chemistry and its relationship to disease. As an educator, he remains committed to shaping the next generation of scientists by integrating critical thinking, computational literacy, and practical laboratory expertise into the learning process. His legacy will likely be defined by both the scientific advancements he enables and the careers he helps foster, ensuring his influence endures in both the laboratory and the classroom.

Publications

  • Theoretical study on the mechanism and kinetics of ring-opening polymerization of cyclic esters initiated by tin(II) n-butoxide — C. Sattayanon, W. Sontising, J. Jitonnom, P. Meepowpan, W. Punyodom, … — 2014

  • Structural switching in self-assembled metal–ligand helicate complexes via ligand-centered reactions — L.R. Holloway, H.H. McGarraugh, M.C. Young, W. Sontising, G.J.O. Beran, … — 2016

  • Theoretical predictions suggest carbon dioxide phases III and VII are identical — W. Sontising, Y.N. Heit, J.L. McKinley, G.J.O. Beran — 2017

  • Effect of halogen substitution on energies and dynamics of reversible photomechanical crystals based on 9-anthracenecarboxylic acid — T.J. Gately, W. Sontising, C.J. Easley, I. Islam, R.O. Al-Kaysi, G.J.O. Beran, … — 2021

  • Theoretical study of the hydrogen abstraction of substituted phenols by nitrogen dioxide as a source of HONO — A. Shenghur, K.H. Weber, N.D. Nguyen, W. Sontising, F.M. Tao — 2014

  • Effects of alkoxide alteration on the ring-opening polymerization of ε-caprolactone initiated by n-Bu3SnOR: a DFT study — C. Sattayanon, W. Sontising, W. Limwanich, P. Meepowpan, W. Punyodom, … — 2015

  • Theoretical assessment of the structure and stability of the ε phase of nitrogen — W. Sontising, G.J.O. Beran — 2019

  • Combining crystal structure prediction and simulated spectroscopy in pursuit of the unknown nitrogen phase ε crystal structure — W. Sontising, G.J.O. Beran — 2020

  • Protocol for spatial metabolomics and isotope tracing in the mouse brain — W. Sontising, F. Yanchik-Slade, C. Rodriguez-Navas, M.A. Hossen, … — 2025

  • Combining Crystal Structure Prediction and Simulated Spectroscopy to Investigate Challenging High Pressure Phases — W. Sontising — 2020

Conclusion

Dr. Sontising’s career demonstrates a rare combination of scientific versatility, teaching excellence, and interdisciplinary innovation. His ability to move fluidly from theoretical chemistry to practical laboratory applications, and finally to biomedical research, underscores a dynamic approach that bridges multiple fields of science. He continues to shape the future of chemistry and neuroscience by developing novel analytical tools while inspiring the next generation of scientists through mentorship and education. His enduring influence lies in both his contributions to advancing knowledge and his commitment to empowering others, marking him as a researcher and educator of lasting impact.

Edythe London | Behavioral Neuroscience | Distinguished Scientist Award

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Dr. Edythe London | Behavioral Neuroscience | Distinguished Scientist Award

Dr. Edythe London | University of California Los Angeles | United States

Dr. Edythe D. London is an internationally recognized neuroscientist and pharmacologist whose career has been dedicated to understanding the brain mechanisms underlying addiction. With a strong academic foundation in zoology, chemistry, pharmacology, and neurobiology, she advanced into leadership roles at the National Institutes of Health before becoming a distinguished professor at UCLA. Her pioneering work in applying brain imaging technologies to addiction research has revealed how drugs alter brain circuits and influence behavior, providing essential knowledge for developing treatments. Beyond research, she has served in influential roles on national policy panels, scientific advisory boards, and university committees, while also mentoring future leaders in the field. Her expertise has been sought after by both academic and pharmaceutical communities, underscoring the breadth of her impact.

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Early Academic Pursuits

Edythe D. London embarked on her academic journey with a deep interest in the biological sciences, pursuing undergraduate studies in zoology with a complementary focus on chemistry. She advanced her training in biological sciences through graduate studies before earning her doctorate in pharmacology with a supporting program in neurobiology. These formative years built a strong foundation for her future career in neuropsychopharmacology, a field she further explored during her postdoctoral fellowship at the Johns Hopkins School of Medicine. Her early academic development was characterized by an integration of biology, chemistry, and neuroscience, which set the stage for her pioneering work in addiction research.

Professional Endeavors

Her professional career began with positions at the National Institute on Aging and later at the National Institute on Drug Abuse, where she advanced from pharmacologist to leadership roles including chief of laboratories and director of brain imaging programs. These responsibilities allowed her to combine pharmacology with cutting-edge neuroimaging approaches. She later transitioned to academia, holding professorial roles at leading institutions including the University of Maryland, Johns Hopkins University, and UCLA. At UCLA, she became the Thomas P. and Katherine K. Pike Professor in Addiction Studies and Distinguished Professor-in-Residence, while also holding an adjunct appointment at the Icahn School of Medicine at Mount Sinai. These roles positioned her at the intersection of research, teaching, and clinical innovation.

Contributions and Research Focus

Dr. London’s work has consistently focused on the neurobiology of addiction and the application of imaging technologies to understand brain function. She pioneered the use of positron emission tomography and functional magnetic resonance imaging to investigate how drugs of abuse alter brain circuits involved in reward, decision-making, and impulse control. Her studies have provided crucial insights into the mechanisms of nicotine, cocaine, methamphetamine, and other substances, while also addressing behavioral and cognitive dimensions of dependence. Beyond drug effects, her research has explored vulnerability factors and treatment responses, shaping both scientific understanding and therapeutic strategies for addiction.

Leadership and Service

In addition to her research, Dr. London has provided leadership in numerous governmental, institutional, and advisory committees. She chaired panels for the Office of National Drug Control Policy, served on central tenure committees for the National Institutes of Health, and contributed to advisory boards at Yale, UC San Diego, Duke, and other leading centers. Her service has extended across animal care, ethics, promotions, and research development programs, reflecting her commitment to strengthening scientific integrity and mentoring new generations of investigators.

Accolades and Recognition

Throughout her career, Dr. London has been recognized as a leading authority in addiction studies and neuropharmacology. Her appointment to named professorships at UCLA underscores the high esteem in which she is held by the academic and medical communities. Invitations to serve on scientific advisory boards, external committees, and national policy panels further highlight the respect accorded to her expertise. She has also been a trusted consultant to major pharmaceutical companies, advising on drug development and the translation of neuroscience discoveries into therapeutic innovation.

Impact and Influence

Dr. London’s influence extends beyond her direct research contributions. Her pioneering integration of brain imaging into addiction science has inspired a generation of researchers to adopt multidisciplinary approaches. By linking pharmacology, neurobiology, and behavioral science, she helped establish addiction research as a rigorous scientific discipline with broad societal relevance. Her mentorship of trainees, leadership in institutional initiatives, and consultation for industry have amplified her impact, ensuring that her work resonates across research, clinical practice, and public health policy.

Legacy and Future Contributions

The legacy of Dr. Edythe D. London lies in her trailblazing role in addiction neuroscience and her enduring influence on the field of brain imaging research. Her contributions continue to guide the development of gender-sensitive treatments, tobacco dependence programs, and innovative strategies for addressing substance use disorders. As a distinguished scholar and mentor, she has set standards for excellence that will shape future research trajectories. Her ongoing involvement in advisory roles and collaborative projects ensures that she remains at the forefront of advancing knowledge in neuroscience and addiction medicine, leaving a lasting imprint on science, medicine, and society.

Publications

  • Comparing neuromodulation targets to reduce cigarette craving and withdrawal: a randomized clinical trial — [Authors not listed in preview] — 2025

  • Brain mGlu5 Is Linked to Cognition and Cigarette Smoking but Does Not Differ From Control in Early Abstinence From Chronic Methamphetamine Use — [Authors not listed in preview] — 2024

  • Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity: A Systematic Review — [Authors not listed in preview] — 2024

  • Structural indices of brain aging in methamphetamine use disorder — [Authors not listed in preview] — 2024

  • Convergent Validity of Experimental Cognitive Tests in a Large Community Sample — [Authors not listed in preview] — 2024

  • Mindfulness and clinical correlates in methamphetamine use disorder — [Authors not listed in preview] — 2023

  • Value-based decision-making predicts alcohol use and related problems in young men — [Authors not listed in preview] — 2023

  • Smoking, tobacco dependence, and neurometabolites in the dorsal anterior cingulate cortex — [Authors not listed in preview] — 2023

  • Polygenic contributions to performance on the Balloon Analogue Risk Task — [Authors not listed in preview] — 2023

  • Negative affect and craving during abstinence from smoking are both linked to default mode network connectivity — [Authors not listed in preview] — 2023

Conclusion

Dr. London’s career reflects a rare combination of scientific innovation, leadership, and service. By bridging pharmacology, neuroimaging, and behavioral science, she transformed the understanding of addiction and shaped therapeutic strategies that continue to influence public health. Her legacy is defined not only by her pioneering discoveries but also by her commitment to advancing research integrity, mentoring emerging scholars, and guiding national and international efforts in addiction medicine. She stands as a highly influential figure whose contributions will continue to inform neuroscience and addiction research for years to come.

Siamak Sorooshyari | Brain Aging | Best Researcher Award

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Dr. Siamak Sorooshyari | Brain Aging | Best Researcher Award

Dr. Siamak Sorooshyari | Stanford | United States

Siamak Sorooshyari is an interdisciplinary scholar whose career spans electrical engineering, statistics, and neuroscience. Beginning with rigorous training in communication theory and wireless networks, he later transitioned into integrative biology, where he applied machine learning to explore signatures of brain aging and neural circuit dynamics. His research contributions have illuminated diverse areas, including functional brain connectivity, dopamine signaling, immune–brain interactions, and computational modeling of neural processes. Currently serving as a postdoctoral scholar in statistics at Stanford University, his work continues to push the boundaries of applied mathematics and neuroscience. Recognized through publications in leading journals and a featured journal cover, his scholarship reflects both depth and breadth, making significant impacts across multiple scientific fields.

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Early Academic Pursuits

Siamak Sorooshyari’s academic journey began with a strong foundation in electrical and computer engineering. His undergraduate and master’s training cultivated a deep interest in wireless communications, coding theory, and the mathematical structures underlying information transmission. During these formative years, he developed a keen analytical mindset and produced thesis work that addressed fundamental questions in multicarrier systems and error performance in communication networks. These early explorations into applied mathematics and engineering set the stage for his later transition into interdisciplinary research at the interface of engineering, biology, and neuroscience.

Transition to Interdisciplinary Research

His intellectual curiosity led him to pursue doctoral studies in integrative biology at the University of California, Berkeley. This marked a pivotal shift in his academic path, where he applied his engineering expertise to complex biological systems. His doctoral thesis focused on machine learning approaches to studying signatures of brain aging across multiple modalities of neural recordings, reflecting both his technical rigor and innovative thinking. This transition demonstrated his ability to bridge diverse fields, integrating computational modeling with biological inquiry to address questions of human health and neuroscience.

Professional Endeavors

Following the completion of his doctoral studies, Sorooshyari joined Stanford University as a postdoctoral scholar in statistics, under the guidance of David Donoho. At Stanford, he has continued to advance statistical and computational methods to explore problems at the intersection of brain science, aging, and network connectivity. His work represents a unique synthesis of applied mathematics, neuroscience, and machine learning, positioning him at the forefront of research that blends theory and data-driven discovery. His professional trajectory reflects a consistent drive to expand disciplinary boundaries while addressing some of the most pressing questions in neuroscience.

Research Contributions and Focus

Sorooshyari’s research contributions span multiple domains, from wireless communications and information theory to computational neuroscience and systems biology. His more recent work has focused heavily on understanding brain aging, dopamine signaling, and neural circuit dynamics through advanced machine learning frameworks. He has explored resting-state functional connectivity, brain–immune interactions, sleep and arousal regulation, and computational models of neural circuit activity. Through this work, he has produced a body of scholarship that not only advances theoretical understanding but also carries translational significance for neurological and psychiatric research.

Accolades and Recognition

His scholarship has been recognized through publications in leading journals such as NeuroImage, PLOS ONE, ACS Chemical Neuroscience, and Frontiers in Computational Neuroscience, among others. Notably, his research on dopamine signaling was featured on the cover of a prominent neuroscience journal, underscoring the visibility and impact of his work within the scientific community. Such recognition reflects his ability to address important scientific questions with methodological sophistication and creativity.

Impact and Influence

The impact of Sorooshyari’s work is evident in its breadth and relevance across disciplines. His contributions to communication theory provided insights into wireless networks, while his more recent neuroscience research has opened new avenues for understanding brain function, aging, and disease. His efforts in applying machine learning to neuroscience highlight the potential of computational methods to uncover biological signatures that may guide diagnostics and therapeutics. By integrating engineering precision with biological complexity, he has influenced both fields and established himself as a key contributor to interdisciplinary science.

Legacy and Future Contributions

Looking ahead, Sorooshyari’s trajectory suggests a continued role in shaping the future of computational neuroscience and applied statistics. His interdisciplinary expertise positions him to contribute to both methodological advancements and practical applications, particularly in the context of brain health and disease modeling. His legacy lies in his ability to cross disciplinary borders, uniting engineering, statistics, and biology to generate insights with profound implications for human health. As he continues his work, his contributions are poised to inspire further innovations in the study of neural systems and their applications in medicine and beyond.

Publications

Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development, H Li, A Watson, A Olechwier, M Anaya, SK Sorooshyari, DP Harnett, …, 2017

Power control for cognitive radio networks: Axioms, algorithms, and analysis, S Sorooshyari, CW Tan, M Chiang, 2011

Autonomous dynamic power control for wireless networks: User-centric and network-centric consideration, S Sorooshyari, Z Gajic, 2008

On the generation of correlated Rayleigh fading envelopes for accurate simulation of diversity channels, S Sorooshyari, DG Daut, 2006

Generation of correlated Rayleigh fading envelopes for accurate performance analysis of diversity systems, S Sorooshyari, DG Daut, 2003

A framework for quantitative modeling of neural circuits involved in sleep-to-wake transition, S Sorooshyari, R Huerta, L de Lecea, 2015

Quantitative and correlational analysis of brain and spleen immune cellular responses following cerebral ischemia, Q Liu, SK Sorooshyari, 2021

On maximum-likelihood SINR estimation of MPSK in a multiuser fading channel, S Sorooshyari, CW Tan, HV Poor, 2010

Conclusion

Sorooshyari’s journey exemplifies the power of interdisciplinary research in addressing complex biological and technological challenges. By merging statistical innovation, computational modeling, and biological inquiry, he has advanced our understanding of neural systems and brain health. His ability to transition seamlessly across disciplines demonstrates both intellectual versatility and visionary research leadership. Looking forward, his contributions hold the promise of shaping future developments in computational neuroscience and translational medicine, ensuring his place as an influential figure in the evolving landscape of interdisciplinary science.

Reza Amani | Clinical Neuroscience | Best Researcher Award

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Prof. Reza Amani | Clinical Neuroscience | Best Researcher Award

Prof. Reza Amani | Isfahan University of Medical Sciences | Iran

Dr. Reza Amani is a distinguished academic and clinical nutritionist whose career has been dedicated to advancing the science of human nutrition and dietetics. His early academic training in nutrition science laid a solid foundation for his extensive research and clinical work in chronic disease management, functional foods, and weight management therapies. He has held key academic and leadership positions, contributed prolifically to scholarly literature, and engaged in international teaching and research collaborations. His expertise has also been recognized through fellowships, visiting professorships, and advisory roles in national health and food policy.

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Early Academic Pursuits

Dr. Reza Amani began his academic journey in the field of nutrition science with a deep commitment to understanding the relationship between diet and health. His early studies in nutrition provided a strong scientific foundation, which he further expanded through advanced degrees in nutrition science. His doctoral research refined his expertise in applied human nutrition and clinical dietetics, laying the groundwork for his future contributions to both academia and clinical practice. These formative years were crucial in shaping his lifelong dedication to advancing knowledge in clinical nutrition and diet therapy.

Professional Endeavors

Over the course of his career, Dr. Amani has held influential academic and leadership positions in leading medical universities, where he has contributed to teaching, mentoring, and program development. His professional endeavors extend beyond academia, with significant roles in nutrition consultation, policy advising, and collaboration with the food industry. Through his service as a head of departments and research centers, he has demonstrated effective leadership in advancing institutional goals while nurturing an environment of academic excellence.

Contributions and Research Focus

Dr. Amani’s scholarly contributions center on clinical nutrition, dietetics, and the therapeutic applications of functional foods. His research has particularly emphasized medical nutrition therapy in chronic diseases, antioxidant-rich diets, and weight management approaches. Through a combination of clinical practice and research, he has explored innovative nutritional solutions and therapeutic diets that address modern health challenges. His body of work reflects a dedication to bridging science and practice, ensuring that research findings translate into effective interventions for public health and patient care.

Academic Publications and Knowledge Dissemination

A prolific scholar, Dr. Amani has authored an extensive collection of scientific papers and academic books in the field of nutrition and dietetics. His publications have enriched the scientific community with insights into functional food formulations, nutritional interventions for chronic disease management, and applied strategies in weight reduction. Beyond publishing, he has actively engaged in organizing and managing academic workshops, seminars, and webinars, ensuring the dissemination of cutting-edge knowledge to a wider audience of professionals, students, and practitioners.

Accolades and Recognition

Dr. Amani’s expertise and commitment have been recognized both nationally and internationally. He has been invited as a visiting scholar and professor at esteemed universities abroad, reflecting his international standing in the field of nutrition science. His fellowship training in clinical nutrition, with a particular focus on obesity management, further underscores his professional recognition and global engagement. His long-term membership in national boards and advisory positions within health ministries and industry demonstrates the trust placed in his expertise at the highest levels of nutrition governance.

Impact and Influence

The impact of Dr. Amani’s work extends across multiple domains, from shaping academic curricula and research priorities to influencing national nutrition policies and guiding food industries. His consultancy roles with health sectors and large industries highlight his ability to apply academic insights to real-world contexts. Moreover, his clinical nutrition practice and ownership of diet therapy clinics serve as a model of integrating academic knowledge with direct patient care. By advancing both scientific knowledge and practical solutions, he has influenced a generation of students, colleagues, and policymakers.

Legacy and Future Contributions

Dr. Amani’s legacy lies in his sustained contributions to clinical nutrition research, his leadership in academic institutions, and his role in shaping health strategies through nutritional science. As a mentor, author, and consultant, he has created pathways for future advancements in functional food research and chronic disease management. Looking forward, his future contributions are expected to continue bridging global collaborations, fostering innovative dietary solutions, and training the next generation of nutrition scientists who will carry forward his vision of integrating scientific research with human health advancement.

Publications

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the … – M Naghavi, KL Ong, A Aali, HS Ababneh, YH Abate, C Abbafati, … – 2024

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease … – M Brauer, GA Roth, AY Aravkin, P Zheng, KH Abate, YH Abate, C Abbafati, … – 2024

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 – JD Steinmetz, KM Seeher, N Schiess, E Nichols, B Cao, C Servili, … – 2024

Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 – SE Vollset, HS Ababneh, YH Abate, C Abbafati, R Abbasgholizadeh, … – 2024

Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 – VL Feigin, MD Abate, YH Abate, S Abd ElHafeez, F Abd-Allah, … – 2024

Does vitamin D improve liver enzymes, oxidative stress, and inflammatory biomarkers in adults with non-alcoholic fatty liver disease? A randomized clinical trial – N Sharifi, R Amani, E Hajiani, B Cheraghian – 2014

Shiftworking, nutrition and obesity: implications for workforce health-a systematic review – R Amani, T Gill – 2013

Inflammatory cytokines and oxidative stress biomarkers in irritable bowel syndrome: association with digestive symptoms and quality of life – R Choghakhori, A Abbasnezhad, A Hasanvand, R Amani – 2017

Global, regional, and national incidence and mortality burden of non-COVID-19 lower respiratory infections and aetiologies, 1990–2021: a systematic analysis from the Global … – RG Bender, SB Sirota, LR Swetschinski, RMV Dominguez, A Novotney, … – 2024

Correlation between dietary zinc intakes and its serum levels with depression scales in young female students – R Amani, S Saeidi, Z Nazari, S Nematpour – 2010

Conclusion

Dr. Amani’s career reflects a remarkable combination of academic scholarship, clinical expertise, and leadership in nutrition science. His contributions have not only advanced research in functional foods and medical nutrition therapy but have also translated into practical health solutions for chronic disease management and weight control. With a legacy of over a hundred publications, leadership in research centers, and consultancy roles at the national level, he stands as a leading figure in the field. Moving forward, his work is set to inspire new generations of nutrition scientists and further strengthen global collaborations in advancing human health through nutrition.

Behjat Ul Mudassir | Neurodevelopmental disorders | Best Researcher Award

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Dr. Behjat Ul Mudassir | Neurodevelopmental disorders | Best Researcher Award

Dr. Behjat Ul Mudassir | Comsats University Islamabad | Pakistan

Dr. Behjat Ul Mudassir is a highly accomplished academic and researcher in the field of molecular genetics and neurogenetics, with a career rooted in rigorous academic excellence. From her early studies in biological sciences at the University of Punjab to advanced training in human genetics at Quaid-i-Azam University and a doctoral degree from COMSATS University Islamabad, she has consistently demonstrated intellectual distinction. Her professional career combines extensive teaching experience with impactful research, focusing particularly on genetic variations linked to neurodevelopmental and neurodegenerative disorders.

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Early Academic Pursuits

From the beginning of her academic journey, Dr. Behjat Ul Mudassir demonstrated exceptional dedication to the life sciences, consistently excelling as an A-grade student. She pursued her undergraduate studies in the biological sciences at the University of Punjab, where she built the foundation for her future specialization. Her strong performance and intellectual curiosity led her to Quaid-i-Azam University, Islamabad, where she completed both a Master of Science and a Master of Philosophy in Human Genetics. These formative years were crucial in shaping her interest in molecular biology and the genetics of complex disorders, eventually culminating in a doctoral degree in Molecular Genetics from COMSATS University Islamabad. Throughout these academic stages, her focus remained on exploring the intricate mechanisms underlying human diseases, particularly those related to the brain.

Professional Endeavors

Dr. Mudassir has built a distinguished career as an academic and researcher, serving as a regular faculty member at Islamabad Model Colleges for many years. She has taught and mentored students in diverse areas of the biological sciences, including genetics, molecular biology, physiology, bioinformatics, and medical microbiology. Her teaching has been especially impactful in the BS Zoology program affiliated with Quaid-i-Azam University, where she continues to guide undergraduates in mastering complex scientific concepts. Alongside her teaching commitments, she has also contributed to national academic bodies, such as serving as a reviewer for BS curriculum development under the Ministry of Federal Education and Professional Training.

Contributions and Research Focus

The central theme of Dr. Mudassir’s research lies in neurogenetics, with a strong emphasis on understanding neurodevelopmental disorders. Her doctoral work and subsequent projects have explored genetic variations linked to conditions such as autism spectrum disorder, attention deficit hyperactivity disorder, and intellectual disability with comorbid epilepsy. She is adept in advanced molecular biology techniques, including whole exome sequencing, chromosomal microarray analysis, gene expression profiling, and RT-PCR, which she applies to uncover novel insights into genetic mechanisms. Beyond human brain disorders, her interests extend to genomics, proteomics, molecular signaling pathways, neurodegeneration, aging, and even the genetic basis of arthritis. This interdisciplinary breadth reflects her commitment to advancing biomedical knowledge through genetics and molecular biology.

Academic and Editorial Contributions

Beyond laboratory research, Dr. Mudassir plays a vital role in the global scientific community as a trusted reviewer and editorial board member for multiple leading publishers. She is part of the Board of Trusted Reviewers at Springer Nature, serves on the Associate Editorial Board for Wiley’s Advanced Genetics Journal, and is a member of the Science Advisory Board in the United States. She also reviews manuscripts for a wide range of journals, including Biochemical Genetics, BMC Medicine, and BMC Pediatrics. These responsibilities highlight her expertise and the recognition she has earned as a reliable evaluator of high-quality scientific work.

Accolades and Recognition

Dr. Mudassir’s excellence as both an educator and a researcher has been acknowledged through numerous awards and honors. She has been recognized with the Best Mentor Award for her guidance in the BS Zoology program and has consistently produced outstanding student results in university examinations. Earlier in her career, she received the Best Teacher Award by Intel International, underscoring her long-standing reputation for excellence in teaching. These recognitions reflect her ability to inspire students and foster a culture of achievement in both research and education.

Impact and Influence

Through her dual role as a researcher and educator, Dr. Mudassir has significantly influenced the fields of molecular genetics and neuroscience in Pakistan. Her work contributes not only to the academic body of knowledge but also to the training of future scientists and healthcare professionals. By bridging cutting-edge research with practical teaching, she has created pathways for students to engage with real-world genetic investigations. Furthermore, her involvement in curriculum development and peer-review activities ensures that the standards of education and research remain rigorous and globally relevant.

Legacy and Future Contributions

Looking ahead, Dr. Mudassir is poised to further expand her impact through the integration of next-generation sequencing, artificial intelligence, and machine learning into genetic research on rare disorders. Her interest in proteomics, cell signaling, and neurodegeneration indicates a forward-looking approach that embraces technological innovation alongside traditional molecular techniques. With her established record of scholarship, mentorship, and international collaboration, her legacy will be defined by both her scientific discoveries and the generations of students and researchers she has inspired. Her future contributions are set to strengthen the bridge between molecular genetics and neuroscience, addressing pressing challenges in human health and advancing knowledge at both national and global levels.

Publications

Denovo variants in POGZ and YY1 genes: The novel mega players for neurodevelopmental syndromes in two unrelated consanguineous families — Behjat Ul Mudassir, Nejat Mahdieh, Mujaddid Mudassir, Jamal B. Williams, Zehra Agha, 2025

Novel and known minor alleles of CNTNAP2 gene variants are associated with comorbidity of intellectual disability and epilepsy phenotypes: a case–control association study reveals potential biomarkers — Behjat Ul Mudassir, Zehra Agha, 2024

Genetic Heterogeneity in Four Probands Reveals HGSNAT, KDM6B, LMNA and WFS1 Related Neurodevelopmental Disorders — Behjat Ul Mudassir, Mujaddid Mudassir, Jamal B. Williams, Zehra Agha, 2024

HGSNAT, KDM6B, LMNA and WFS1 genes pathophysiological heterogeneity for neurodevelopmental disorders reveals novel, rare and ultra-rare variants in four unrelated probands of consanguineous families — Behjat Mudassir, Zehra Agha, 2024

Novel and known minor alleles of CNTNAP2 gene variants are associated with comorbidity of intellectual disability and epilepsy phenotypes: A case-control association study — Behjat Mudassir, Zehra Agha, 2023

Genome-wide CNV analysis uncovers novel pathogenic regions in cohort of five multiplex families with neurodevelopmental disorders — Behjat Ul Mudassir, Mashael Alhumaidi Alotaibi, Nadeem Kizilbash, Daliyah Alruwaili, Anwar Alruwaili, Modhi Alenezi, Zehra Agha, 2023

Novel biallelic frameshift in TRPM7 gene causes Hallermann–Streiff syndrome in a consanguineous family: a case report — Behjat Mudassir, Zehra Agha, 2023

Microcephaly, Short Stature, Intellectual Disability, Speech Absence and Cataract Are Associated with Novel Bi-Allelic Missense Variant in RTTN Gene: A Seckel Syndrome Case Report — Behjat Ul Mudassir, Zehra Agha, 2023

CNTNAP2 Associated Neurodevelopmental Disorders: Intellectual Disability and Epilepsy comorbidity in Pakistani population — Behjat Mudassir, 2022

Conclusion

Dr. Mudassir stands out as a dedicated scientist, mentor, and reviewer whose research in neurogenetics addresses critical challenges in understanding complex brain disorders. Her commitment to advancing molecular biology and genetics, combined with her influential teaching and editorial contributions, positions her as a valuable leader in her field. With her forward-looking vision that embraces advanced technologies and interdisciplinary collaboration, she is set to leave a lasting legacy in biomedical research and education. Her career reflects not only personal excellence but also a broader impact on science, students, and society.