Prof. Dr. James Shine | The University of Sydney | Australia
This researcher is an influential systems neurobiologist whose work has significantly advanced the scientific understanding of whole-brain neural dynamics. With over 170 peer-reviewed publications, more than 16,000 citations, an h-index of 67, and an i10-index of 177, their scholarly contributions have shaped multiple domains within contemporary neuroscience. Their research integrates multimodal neuroimaging, computational modelling, network science, and systems-level neurobiology to uncover the principles governing cognition, attention, and consciousness. A major focus of their work involves developing biophysically informed models that link neuroanatomical organization with large-scale patterns of human brain activity, enabling the generation of testable predictions across imaging modalities. Their publications span impactful studies in neuroimaging, neurobiology, and computational science, including widely cited papers in high-profile journals. Their seminal insights into dynamic functional brain network integration have catalyzed global interest in time-resolved brain connectivity, influencing methodological developments and being adopted by more than 100 research groups across over 90 countries. Their research program also advances innovative computational frameworks for analysing complex neural signals, contributing both theoretical and practical tools that inform the study of neurodegenerative conditions and cognitive function. their work continues to shape the direction of systems neuroscience and quantitative brain research.
Featured Publications
Shine, J. M., Bissett, P. G., Bell, P. T., Koyejo, O., Balsters, J. H., Gorgolewski, K. J., … (2016). The dynamics of functional brain networks: Integrated network states during cognitive task performance. Neuron, 92(2), 544–554.
Hansen, J. Y., Shafiei, G., Markello, R. D., Smart, K., Cox, S. M. L., Nørgaard, M., … (2022). Mapping neurotransmitter systems to the structural and functional organization of the human neocortex. Nature Neuroscience, 25(11), 1569–1581.
Lurie, D. J., Kessler, D., Bassett, D. S., Betzel, R. F., Breakspear, M., Kheilholz, S., … (2020). Questions and controversies in the study of time-varying functional connectivity in resting fMRI. Network Neuroscience, 4(1), 30–69.
Shine, J. M., Breakspear, M., Bell, P. T., Ehgoetz Martens, K. A., Shine, R., … (2019). Human cognition involves the dynamic integration of neural activity and neuromodulatory systems. Nature Neuroscience, 22(2), 289–296.
Poldrack, R. A., Laumann, T. O., Koyejo, O., Gregory, B., Hover, A., Chen, M. Y., … (2015). Long-term neural and physiological phenotyping of a single human. Nature Communications, 6, 8885.
Shine, J. M., Matar, E., Ward, P. B., Frank, M. J., Moustafa, A. A., Pearson, M., … (2013). Freezing of gait in Parkinson’s disease is associated with functional decoupling between the cognitive control network and the basal ganglia. Brain, 136(12), 3671–3681.