Edyta GLOGOWSKA | Cell Metabolism | Best Researcher Award

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Dr. Edyta Glogowska | Cell Metabolism | Best Researcher Award

Dr.  Edyta Glogowska, CNRS-IPMC-UniCA,  France.

Dr. Edyta Glogowska is a passionate and accomplished biomedical researcher with a strong academic background in biotechnology and life sciences. From her early beginnings in dental engineering to earning a PhD in red blood cell physiology from the University Pierre and Marie Curie, her academic journey reflects a deep commitment to advancing human health through science. Her postdoctoral research at the Institute of Molecular and Cellular Pharmacology (IPMC) highlights her expertise in cell physiology, electrophysiology, and molecular biology, with a special focus on macrophage Piezo1 channels and their role in atherosclerosis. She is a skilled communicator and team collaborator, recognized for her academic excellence and contributions to hematology and immunopathology.

Profile

Scopus

🎓 Early Academic Pursuits

Dr. Edyta Glogowska’s journey into the world of life sciences began with a strong foundation in biotechnology and medical sciences. She earned her Master of Engineering in Biotechnology Processing from Wroclaw University of Science and Technology, where she graduated with highest honors. Even earlier, she had already laid a unique cornerstone for her biomedical interests through specialized training as a Dental Engineer at the Marie Curie Medical Vocational School. Her pursuit of deeper scientific knowledge led her to France, where she undertook her PhD in Biological and Life Sciences at the University Pierre and Marie Curie, Paris VI. Conducted at the prestigious Station Biologique in Roscoff, her doctoral research focused on red blood cell physiology and was awarded with the highest honors—a testament to her early dedication and scientific promise.

🔬 Professional Endeavors

Dr. Glogowska’s professional career has been marked by a steadfast commitment to cell and molecular biology, electrophysiology, and the biochemistry of proteins. Her postdoctoral research at the Institute of Molecular and Cellular Pharmacology (IPMC) in Sophia Antipolis (2021–2024) showcases her hands-on expertise with mice experimentation and patch-clamp techniques, placing her at the cutting edge of biomedical research. Working under the guidance of Dr. Eric Honoré, she explored the role of macrophage Piezo1 channels regulated by lipids, a study with far-reaching implications in understanding and potentially treating atherosclerosis.

🧬 Contributions and Research Focus

Throughout her academic and postdoctoral years, Dr. Glogowska has focused her research on the physiology and pathophysiology of cells, particularly red blood cells and immune cells like macrophages. Her interest lies in understanding how cellular mechanisms contribute to broader medical conditions, such as cardiovascular diseases. By integrating electrophysiology with molecular biology, she brings a comprehensive approach to biomedical questions, bridging the gap between basic research and therapeutic application. Her work on Piezo1 not only contributes to our understanding of mechanotransduction in macrophages but also holds promise for future translational research.

🏅 Accolades and Recognition

Dr. Glogowska’s scholarly excellence has been consistently recognized. She graduated with highest honors both for her Master’s and PhD degrees, a rare academic distinction that underscores her dedication and intellectual rigor. She has also been an active member of the French Society of Hematology, aligning herself with leading experts in her field and staying abreast of the latest developments in blood cell research. These accolades reflect her respected standing within the scientific community.

🌍 Impact and Influence

Beyond technical expertise, Dr. Glogowska is praised for her team coordination and communication skills, qualities that have enabled her to contribute meaningfully to collaborative research environments. Her scientific efforts in understanding lipid–ion channel interactions in macrophages directly influence the broader field of cardiovascular immunology. By elucidating the role of Piezo1 channels in inflammatory processes, her research provides foundational knowledge that can inspire novel pharmacological interventions.

🔎 Legacy and Future Contributions

Dr. Glogowska continues to strive toward a future where her research leads to medical breakthroughs in inflammation and cardiovascular disease. She is particularly interested in translational science, where laboratory discoveries transition into clinical applications. Her strong background in biotechnology, dentistry, and molecular biology uniquely equips her to explore cross-disciplinary challenges in human health. As she advances, she aims to bridge research with clinical solutions, contributing to a legacy of innovation in life sciences.

Publication

Title: Potentiation of macrophage Piezo1 by atherogenic 7-ketocholesterol
Authors: Edyta Glogowska, Gregor P. Jose, Ana Rita Dias Araújo, Laurent Yvan-Charvet, Éric R. Honoré
Year: 2025

Title: Piezo1 in PASMCs: Critical for Hypoxia-Induced Pulmonary Hypertension Development
Authors: Fenja Knoepp, Shariq Abid, Amal Houssaïni, Éric R. Honoré, Serge Adnot
Year: 2025

Title: Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion
Authors: Rakhee Lohia, Benoit Allegrini, Laurence Berry, Éric R. Honoré, Kai Wengelnik
Year: 2023

Title: A machine-learning algorithm integrating baseline serum proteomic signatures predicts exercise responsiveness in overweight males with prediabetes
Authors: Candela Diaz-Canestro, Jiarui Chen, Yan Liu, Michael Andrew Tse, Aimin Xu
Year: 2023

Title: Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects
Authors: Kang Chen, Lai Yee Cheong, Yuan Gao, Hannah Xiaoyan Hui, Aimin Xu
Year: 2022

Title: Author Correction: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
Authors: Shengpeng Wang, Shuang Cao, Malika Arhatte, Éric R. Honoré, Stefan Offermanns
Year: (Correction Published) — Likely 2021 or 2022

Title: Piezo1 and Piezo2 foster mechanical gating of K2P channels
Authors: Edyta Glogowska, Malika Arhatte, Franck C. Chatelain, Amanda Jane Patel, Éric R. Honoré
Year: 2021

Title: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
Authors: Shengpeng Wang, Shuang Cao, Malika Arhatte, Éric R. Honoré, Stefan Offermanns
Year: 2020

Title: Piezo Ion Channels in Cardiovascular Mechanobiology
Authors: Dominique Douguet, Amanda Jane Patel, Aimin Xu, Paul Michel Vanhoutte, Éric R. Honoré
Year: (Not explicitly stated, likely ~2020 based on context)

Title: TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells
Authors: Malika Arhatte, Gihan S. Gunaratne, Charbel El Boustany, Éric R. Honoré, Amanda Jane Patel
Year: 2019

 

 

✅ Conclusion

Driven by curiosity and guided by precision, Dr. Glogowska continues to make meaningful strides in biomedical research. Her work stands at the intersection of basic science and medical application, with the potential to influence future therapeutic strategies for cardiovascular and inflammatory diseases. With her versatile skill set and visionary approach, she is well-positioned to leave a lasting impact on the scientific and medical communities. As she moves forward, Dr. Glogowska aspires to further bridge laboratory discoveries with clinical innovations, fostering a legacy of scientific excellence and translational breakthroughs.

 

Paolo Grumati | Cell Biology | Best Researcher Award

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Prof. Paolo Grumati | Cell Biology | Best Researcher Award

Prof. Paolo Grumati,  TIGEM, Italy.

Dr. Paolo Grumati is a prominent researcher and academic with a focus on molecular biology, particularly the study of autophagy and its role in diseases such as muscular dystrophies and neurodegenerative disorders. His academic journey, beginning with a Master’s and Ph.D. from the University of Padova, laid the foundation for his pioneering work in the molecular mechanisms underlying disease pathogenesis. Dr. Grumati’s professional endeavors have included roles at esteemed institutions like Johann Wolfgang Goethe University and the Telethon Institute of Genetics and Medicine (TIGEM), where he leads groundbreaking research in selective autophagy. His work, which integrates advanced techniques like CRISPR/Cas9, has earned him widespread recognition and numerous accolades, including positions as Associate Professor at the University of Naples. His research has had a significant impact on the scientific community, particularly in the areas of cellular maintenance and therapeutic development.

Profile

Scopus

 

Early Academic Pursuits 🎓


Paolo Grumati’s academic journey began at the University of Padova in Italy, where he pursued a Master’s Degree in Medical Biotechnologies, graduating in 2005. His deep curiosity in the molecular underpinnings of human biology led him to continue his studies with a Ph.D. in Genetic and Molecular Biology, completed between 2006 and 2009. During his Ph.D., he focused on the genetic mechanisms that contribute to various diseases, a pursuit that sparked his lasting interest in molecular biology and disease pathogenesis. His early academic training laid a strong foundation for his future research in the biochemistry of diseases, especially those that affect muscle function and cellular processes.

Professional Endeavors 💼


Dr. Grumati’s professional career has been marked by an impressive trajectory across prestigious institutions. After completing his postdoctoral work on the pathogenesis of muscular dystrophies at the University of Padova, he moved to Germany, where he took a position at the Institute of Biochemistry II at Johann Wolfgang Goethe University. There, between 2013 and 2018, he specialized in the biochemistry and molecular biology of autophagy, a crucial cellular process related to health and disease. His expertise in autophagy became a defining element of his career, and in 2019, he was appointed as the Assistant Investigator and Head of the Mass Spectrometry Core at the Telethon Institute of Genetics and Medicine (TIGEM), where he leads innovative research into the molecular mechanisms of selective autophagy. Throughout these roles, Dr. Grumati has built a reputation for integrating advanced techniques like CRISPR/Cas9 into his work, influencing the field of genetic research.

Contributions and Research Focus 🔬


Dr. Grumati’s research focus has consistently revolved around the intricate molecular processes that govern cellular maintenance and disease, particularly through the lens of autophagy. Since becoming a principal investigator in 2019, his work at TIGEM has concentrated on understanding the molecular mechanisms of selective autophagy, which plays a pivotal role in cellular health and disease. He has pioneered methods to study and manipulate these processes, contributing significantly to the understanding of diseases such as muscular dystrophies and neurodegenerative disorders. His research not only delves into the underlying biology of these conditions but also seeks to identify therapeutic targets that could help manage or even cure these diseases.

Accolades and Recognition 🏆


Dr. Grumati has received widespread recognition for his work in molecular biology and biochemistry. His contributions to the field of autophagy and muscle biology have been honored with leadership roles in prominent research teams, including his time as Team Leader of the Frankfurt CRISPR/Cas9 Screening Center. His excellence in research has earned him a faculty position as Assistant Professor at the University of Naples “Federico II” and an eventual promotion to Associate Professor in 2024. His expertise in mass spectrometry and molecular biology has also made him a sought-after figure in the scientific community, where he is frequently invited to collaborate on interdisciplinary research projects.

Impact and Influence 🌍


Dr. Grumati’s research has had a lasting impact on the scientific community, particularly in the fields of autophagy and muscular dystrophies. His work has influenced both theoretical and applied aspects of molecular biology, from basic research to potential therapeutic interventions. Through his leadership at TIGEM and his involvement in international collaborations, Dr. Grumati has helped to shape the direction of research into autophagy-related diseases. His studies have not only provided insights into the cellular mechanisms at play in these diseases but also paved the way for future therapeutic strategies. He is seen as a key figure in the advancement of precision medicine and molecular therapeutics.

Legacy and Future Contributions 🔮

As Dr. Grumati moves forward in his career, his contributions to the fields of genetics and molecular biology are expected to have a profound and lasting influence. His current work, focusing on selective autophagy, holds promise for the development of novel treatments for diseases that currently have limited therapeutic options. His legacy will likely include innovations in understanding cellular degradation processes and their application to genetic disorders and other diseases. The future of Dr. Grumati’s research will continue to explore the molecular intricacies of human health, offering the potential for breakthroughs in regenerative medicine and disease treatment.

Teaching and Mentorship 👨‍🏫


Beyond his research, Dr. Grumati has made a significant impact through his academic roles at the University of Naples. As an Associate Professor, he plays a key role in shaping the next generation of molecular biologists. His teaching focuses on imparting knowledge in genetics, biochemistry, and molecular biology, with an emphasis on practical research applications. His mentorship has helped guide many students and early-career researchers, who have gone on to make their own contributions to the field. Dr. Grumati’s ability to translate complex scientific concepts into accessible lessons ensures that his influence extends far beyond his own research.

Publication

  • Title: Cortico-striatal circuit mechanisms drive the effects of D1 dopamine agonists on memory capacity in mice through cAMP/PKA signalling
    Authors: M. de Risi, D. Cavezza, G. Torromino, P. Grumati, E. de Leonibus
    Year: 2025

 

  • Title: Two FAM134B isoforms differentially regulate ER dynamics during myogenesis
    Authors: V. Buonomo, K.O. Lohachova, A. Reggio, R.M. Bhaskara, P. Grumati
    Year: 2025

 

  • Title: Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling
    Authors: G. Giamundo, D. Intartaglia, E. del Prete, R. De Cegli, I. Conte
    Year: 2025

 

  • Title: 3D Rotary Wet-Spinning (RoWS) Biofabrication Directly Affects Proteomic Signature and Myogenic Maturation in Muscle Pericyte–Derived Human Myo-Substitute
    Authors: A. Reggio, C. Fuoco, F. de Paolis, M. Costantini, C. Gargioli
    Year: 2025

 

  • Title: Cross-Linking Mass Spectrometry to Capture Protein Network Dynamics of Cell Membranome
    Authors: L. Santorelli, M. Costanzo, S. Petrosino, M. Ruoppolo, P. Grumati
    Year: 2025

 

  • Title: Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces
    Authors: P. Romani, G. Benedetti, M. Cusan, G. Martello, S. Dupont
    Year: 2024

 

Conclusion


Dr. Paolo Grumati’s career exemplifies the integration of scientific inquiry with practical application, as his research continues to shed light on crucial molecular processes that affect human health. His contributions to the understanding of autophagy have opened new avenues for potential therapeutic strategies in treating genetic disorders and other diseases. As he continues to lead research at TIGEM and teach at the University of Naples, Dr. Grumati’s legacy is set to influence the fields of molecular biology, genetics, and medicine for years to come. His work remains pivotal in advancing both the theoretical understanding of disease mechanisms and the development of new therapeutic approaches, positioning him as a key figure in modern biomedical research.