Bastian Höchst | Onco- Immunology | Best Researcher Award

Dr. Bastian Höchst | Onco- Immunology | Best Researcher Award

Dr. Bastian Höchst,  Institute of Molecular Immunology, MRI, TUM, Germany.

Bastian Höchst is a distinguished molecular immunologist whose career spans groundbreaking research, impactful teaching, and valuable contributions to the scientific community. His academic journey began with a focus on biology and culminated in a doctorate on immune regulation in liver tumors. As a Research Group Leader at the Technical University of Munich, he investigates the complex interplay of immune cells and tissues in acute and chronic inflammation. His pioneering discoveries, such as the mechanisms governing myeloid suppressor cells and immune-regulatory metabolite transfer, have advanced understanding in the field.

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🌱 Early Academic Pursuits

Bastian Höchst began his academic journey with a passion for understanding the intricate mechanisms of biology. From 1999 to 2005, he pursued his studies in Biology at the University of Bonn and Hamburg, laying the foundation for his future endeavors in molecular immunology. His academic curiosity led him to pursue a doctorate at the Medical School Hannover under the guidance of Prof. Dr. Tim F. Greten. His doctoral research focused on identifying and characterizing myeloid-derived suppressor cells in patients with hepatocellular carcinoma, marking the beginning of his impactful contributions to the field of immunology.

🔬 Professional Endeavors

Currently serving as a Research Group Leader at the Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University of Munich (TUM), Bastian Höchst has dedicated his career to unraveling the complexities of immune regulation. His journey in academia has been marked by significant roles, including his previous tenure as a Research Group Leader at the Institute for Animal Physiology and Immunology, Wissenschaftszentrum Weihenstephan, TUM. Additionally, his postdoctoral fellowship at the Institute of Molecular Medicine and Experimental Immunology at the University of Bonn further honed his expertise in immune mechanisms.

🧪 Contributions and Research Focus

Bastian Höchst’s research delves into immune regulation within acute and chronic inflammatory processes, with a particular focus on tissue-specific mechanisms. He has made groundbreaking discoveries, including elucidating the pathways that govern the generation of myeloid suppressor cells in liver tumors. Furthermore, his innovative work revealed that the intercellular transfer of immune-regulatory metabolites is critical to T-cell effector functions. His research has significantly advanced the understanding of immune responses in disease contexts, bridging gaps in immunological knowledge.

🎓 Teaching and Mentorship

A dedicated educator, Bastian Höchst has been actively involved in teaching since 2010, inspiring students in life sciences programs at TUM. His lectures on topics such as onco-immunology, immune metabolism, and immunotherapy provide invaluable insights to aspiring scientists. Through lab courses on immune cell phenotyping and advanced techniques like spectral flow cytometry, he has empowered students with the skills to explore the complexities of immunology. His teaching contributions extend beyond knowledge dissemination, fostering a generation of critical thinkers and innovators.

📜 Accolades and Recognition

Bastian’s expertise has been recognized through his habilitation and venia legendi for Molecular Immunology, under the mentorship of Prof. Dr. Percy Knolle. His contributions as a scientific reviewer for prestigious journals like Hepatology, Journal of Hepatology, and Frontiers in Immunology further reflect his authority in the field. Additionally, his role in evaluating grant applications for the Deutsche Forschungsgemeinschaft (DFG) underscores his impact on shaping future research initiatives.

🌍 Impact and Influence

Through his research, teaching, and reviews, Bastian Höchst has left an indelible mark on the field of molecular immunology. His work not only uncovers critical mechanisms of immune regulation but also provides pathways for therapeutic advancements in inflammatory and tumor-related conditions. His contributions influence both scientific understanding and practical applications, addressing global challenges in health and disease management.

🌟 Legacy and Future Contributions

Bastian Höchst’s journey is one of passion, discovery, and impact. As he continues to lead groundbreaking research, he sets the stage for a future where immune-based therapies are revolutionized. His legacy lies in his ability to connect fundamental research with real-world applications, inspiring colleagues and mentees alike. With his unwavering commitment to scientific exploration, Bastian Höchst is poised to shape the future of molecular immunology, paving the way for transformative breakthroughs.

Publication

  • A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4+ CD25+ Foxp3+ T cells
    Authors: B. Höchst, L.A. Ormandy, M. Ballmaier, F. Lehner, C. Krüger, M.P. Manns, …
    Year: 2008

 

  • Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor
    Authors: B. Höchst, T. Voigtlaender, L. Ormandy, J. Gamrekelashvili, F. Zhao, …
    Year: 2009

 

  • Functional classification of memory CD8+ T cells by CX3CR1 expression
    Authors: J.P. Böttcher, M. Beyer, F. Meissner, Z. Abdullah, J. Sander, B. Höchst, …
    Year: 2015

 

  • Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells
    Authors: B. Höchst, J. Gamrekelashvili, M.P. Manns, T.F. Greten, F. Korangy
    Year: 2011

 

  • S100A9 a new marker for monocytic human myeloid‐derived suppressor cells
    Authors: F. Zhao, B. Höchst, A. Duffy, J. Gamrekelashvili, S. Fioravanti, M.P. Manns, …
    Year: 2012

 

  • Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal
    Authors: T. Baumann, A. Dunkel, C. Schmid, S. Schmitt, M. Hiltensperger, K. Lohr, …
    Year: 2020

 

  • Kupffer cell-derived Tnf triggers cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS
    Authors: D. Yuan, S. Huang, E. Berger, L. Liu, N. Gross, F. Heinzmann, M. Ringelhan, …
    Year: 2017

 

  • Low-dose cyclophosphamide treatment impairs regulatory T cells and unmasks AFP-specific CD4+ T-cell responses in patients with advanced HCC
    Authors: T.F. Greten, L.A. Ormandy, A. Fikuart, B. Höchst, S. Henschen, M. Hörning, …
    Year: 2010

 

Conclusion

Bastian Höchst’s career exemplifies dedication to advancing molecular immunology through innovative research, education, and mentorship. His contributions have shaped the understanding of immune responses in disease contexts, offering hope for novel therapeutic approaches. As he continues to lead impactful research and foster new talent, Bastian Höchst remains a visionary in his field, poised to drive future breakthroughs that bridge science and medicine for the benefit of society.

 

Alytia Levendosky | Behavioral Neuroscience | Best Researcher Award

Dr. Alytia Levendosky | Behavioral Neuroscience | Best Researcher Award

Dr. Alytia Levendosky, Michigan State University, United States.

Alytia Akiko Levendosky’s academic journey began with a strong foundation in Biological Anthropology at Harvard-Radcliffe College, where she graduated Magna Cum Laude. Her passion for understanding the complexities of human behavior led her to pursue advanced studies in Clinical Psychology at the University of Michigan, culminating in a Ph.D. in 1995. As a professor at Michigan State University, she has excelled in research and teaching, making significant contributions to the study of mental health, developmental psychology, and human behavior. Her work reflects a balance of intellectual rigor, compassion, and a dedication to advancing the field.

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Scopus

🌱 Early Academic Pursuits

Alytia Akiko Levendosky began her remarkable academic journey at Harvard-Radcliffe College, where she pursued a Bachelor of Arts in Biological Anthropology, graduating Magna Cum Laude in 1987. Her early fascination with the biological and psychological dimensions of human behavior laid a strong foundation for her future endeavors. Harvard’s intellectually vibrant environment nurtured her curiosity, sparking a lifelong passion for understanding human development and mental health.

🎓 Professional Endeavors in Psychology

After completing her undergraduate studies, Alytia delved deeper into the field of psychology at the University of Michigan, earning her Master’s degree in Clinical Psychology in 1992 and a Ph.D. in 1995. Her doctoral work showcased her commitment to unraveling the complexities of clinical psychology, marking her as a rising star in the discipline. As a faculty member in the Department of Psychology at Michigan State University, she dedicated herself to advancing both research and teaching. Her contributions to the academic community have made her an influential figure in the field.

🧠 Contributions to Research and Understanding

Alytia’s research has primarily focused on clinical psychology, with a particular interest in the interaction between biological and psychological factors in human behavior. Through her work, she has contributed significant insights into mental health, developmental psychology, and behavioral patterns. Her scholarly pursuits reflect a balance of rigorous scientific inquiry and a compassionate understanding of the human condition.

🌟 Accolades and Recognition

Throughout her academic career, Alytia has been celebrated for her intellectual contributions and dedication to teaching. Her ability to inspire students and colleagues alike has earned her a place of respect and admiration in the academic world. Her research achievements and the success of her students speak volumes about her influence as an educator and mentor.

🌍 Impact on Mental Health and Human Development

Alytia’s work has had a profound impact on the study of mental health and human development. By integrating clinical practices with research, she has advanced the understanding of complex psychological phenomena, contributing to improved therapeutic approaches. Her dedication to fostering a deeper comprehension of mental well-being has resonated far beyond the classroom and the research lab.

🔑 Legacy of Knowledge and Insight

Alytia’s enduring legacy lies in her commitment to pushing the boundaries of knowledge in psychology. Her intellectual rigor and empathetic perspective have left an indelible mark on her students, colleagues, and the broader psychological community. The ripple effects of her work continue to influence future generations of psychologists and researchers.

🚀 Future Contributions to Psychology

With her rich background in clinical psychology and her passion for research, Alytia remains poised to make further contributions to the field. Her ongoing efforts to bridge gaps in understanding human behavior promise to drive new discoveries and inspire meaningful progress in mental health care and psychological research.

 

Publications

  • Parenting in battered women: The effects of domestic violence on women and their children
    Authors: AA Levendosky, SA Graham-Bermann
    Year: 2001

 

  • The impact of domestic violence on the maternal-child relationship and preschool-age children’s functioning
    Authors: AA Levendosky, AC Huth-Bocks, DL Shapiro, MA Semel
    Year: 2003

 

  • Resilience among children exposed to domestic violence: The role of risk and protective factors
    Authors: C Martinez-Torteya, G Anne Bogat, A Von Eye, AA Levendosky
    Year: 2009

 

  • Traumatic stress symptoms in children of battered women
    Authors: SA Graham-Bermann, AA Levendosky
    Year: 1998

 

  • Phase-shifting effects of bright morning light as treatment for delayed sleep phase syndrome
    Authors: NE Rosenthal, JR Joseph-Vanderpool, AA Levendosky, SH Johnston, …
    Year: 1990

 

  • Trauma symptoms among infants exposed to intimate partner violence
    Authors: GA Bogat, E DeJonghe, AA Levendosky, WS Davidson, A Von Eye
    Year: 2006

 

  • Domestic violence, maternal parenting, maternal mental health, and infant externalizing behavior
    Authors: AA Levendosky, KL Leahy, GA Bogat, WS Davidson, A Von Eye
    Year: 2006

 

  • Trauma symptoms in preschool-age children exposed to domestic violence
    Authors: AA Levendosky, AC Huth-Bocks, MA Semel, DL Shapiro
    Year: 2002

 

  • Adolescent survivors of childhood sexual abuse: The mediating role of attachment style and coping in psychological and interpersonal functioning
    Authors: DL Shapiro, AA Levendosky
    Year: 1999

 

  • The direct and indirect effects of domestic violence on young children’s intellectual functioning
    Authors: AC Huth-Bocks, AA Levendosky, MA Semel
    Year: 2001

 

🌟 Conclusion

Alytia’s career is a testament to her profound commitment to unraveling the complexities of the human mind and fostering mental well-being. Through her research, teaching, and mentorship, she has inspired countless students and peers, leaving a lasting impact on the field of psychology. As she continues her journey, her contributions promise to shape the future of psychological research, ensuring that her legacy will endure for generations to come.

Liliane Massade | Targeted therapy | Innovation in Neuroscience Award

Liliane Massade | Targeted therapy | Innovation in Neuroscience Award

Dr. Liliane Massade, INSERM, France.

Dr. Liliane Massade is a visionary research leader whose work integrates molecular biology, nanotechnology, and translational medicine. From her academic roots in Lebanon to her pioneering research in France, she has achieved significant milestones, including the development of siRNA-based therapies for Charcot-Marie-Tooth disease and innovations in neurodegenerative and cancer treatments. Her career spans decades of groundbreaking discoveries, interdisciplinary collaborations, and impactful mentorship. With over 78 publications, patents, and numerous awards, Dr. Massade’s contributions are both scientifically profound and globally influential.

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🌟 Early Academic Pursuits

Dr. Liliane Massade’s academic journey began with her passion for biology and education. After earning her Master’s in Biology from Lebanese University in 1982, she followed her calling as a teacher, obtaining a Teaching Diploma from Ecole Normale, Lebanon, in 1981. Her thirst for knowledge led her to Paris Diderot University, where she completed an Advanced Studies Diploma (DEA) in Population Genetics and Evolution in 1986. By 1990, she had earned her Ph.D. in Population Genetics and Evolution, marking the start of her illustrious career. In 1996, she achieved the Authorization to Supervise Research (HDR), solidifying her role as a mentor and leader in her field.

🔬 Professional Endeavors

Dr. Massade’s career has been a symphony of innovation, leadership, and groundbreaking research. Since 2020, she has led a cutting-edge team at U1195 INSERM, Bicêtre University Hospital, focusing on targeted therapies for chemotherapy-induced peripheral neuropathies. Prior to this, she helmed teams at UMR 8203 CNRS, Gustave Roussy Institute, where she advanced anti-cancer therapies and explored molecular targets in thyroid cancer. Her earlier work at INSERM and CNRS saw her delve into estradiol signaling in breast cancer and enzymes in drug metabolism, laying the foundation for her expertise in molecular biology and translational medicine.

💡 Contributions and Research Focus

Dr. Massade’s pioneering spirit has transformed the fields of neurodegenerative diseases and oncology. She is celebrated for her groundbreaking siRNA-based therapies targeting PMP22, which have opened new horizons for Charcot-Marie-Tooth disease treatment. Her innovations extend beyond therapy, as her patented methods in nucleic acid transfer highlight her interdisciplinary approach. With a focus on integrating biology, chemistry, and nanotechnology, she leads research that merges fundamental science with clinical application, offering hope for conditions like peripheral neuropathy and neurodegeneration.

🏆 Accolades and Recognition

Throughout her career, Dr. Massade has earned prestigious accolades, including the Outstanding Achievement Award at the World Congress on Advances in Oncology in 2013 and the JW Griffin Prize for Regeneration from the Peripheral Nerve Society in 2021. Her impact is further underscored by her extensive publication record, with 78 works, an H-index of 26, and over 49 invited talks at international conferences. These honors reflect her global influence and her ability to inspire the next generation of researchers.

🌍 Impact and Influence

Dr. Massade’s contributions extend beyond her lab, as she evaluates research programs for renowned organizations like the ERC, ANR, and ARC. As a member of international committees such as LaBEX NanoSaclay, she ensures the advancement of cutting-edge nanotechnology. Her mentorship has shaped the careers of 10 postdoctoral researchers, 11 Ph.D. candidates, and 31 Master’s students, demonstrating her commitment to nurturing scientific talent.

🔗 Legacy and Future Contributions

As the co-founder of MAAsiRNA, Dr. Massade exemplifies the translation of research into real-world impact. With €7 million raised to develop therapies targeting PMP22, her work bridges the gap between science and patient care. Her vision for the future includes continued exploration of siRNA therapies and the development of innovative approaches to neuroprotection and cancer treatment. Her legacy is one of scientific excellence, interdisciplinary collaboration, and unwavering dedication to improving lives through research.

📚Publications

  • GRT-X Stimulates Dorsal Root Ganglia Axonal Growth in Culture via TSPO and Kv7.2/3 Potassium Channel Activation
    Authors: Léa El Chemali, Suzan Boutary, Song Liu, Guo-Jun Liu, Ryan J. Middleton, Richard B. Banati, Gregor Bahrenberg, Rainer Rupprecht, Michael Schumacher, Liliane Massaad-Massade
    Year: 2024

 

  • Optimizing Structure and Activity of the Squalenoyl-siRNA Nanoparticles
    Author: Liliane Massaad-Massade
    Year: 2023

 

  • Mutation of Proteolipid Protein 1 Gene: From Severe Hypomyelinating Leukodystrophy to Inherited Spastic Paraplegia
    Authors: Guy Khalaf, Claudia Mattern, Mélina Begou, Odile Boespflug-Tanguy, Charbel Massaad, Liliane Massaad-Massade
    Year: 2022

 

  • The Mitochondrial Translocator Protein (TSPO): A Key Multifunctional Molecule in the Nervous System
    Authors: Léa El Chemali, Yvette Akwa, Liliane Massaad-Massade
    Year: 2022

 

  • Supramolecular Organization and Biological Interaction of Squalenoyl siRNA Nanoparticles
    Authors: Marie Caillaud, Frédéric Gobeaux, Miryana Hémadi, Suzan Boutary, Patrick Guenoun, Didier Desmaële, Patrick Couvreur, Frank Wien, Fabienne Testard, Liliane Massaad-Massade
    Year: 2021

 

  • Squalenoyl siRNA PMP22 Nanoparticles Are Effective in Treating Mouse Models of Charcot-Marie-Tooth Disease Type 1A
    Author: Liliane Massaad-Massade
    Year: 2021

 

  • Treating PMP22 Gene Duplication-Related Charcot-Marie-Tooth Disease: The Past, the Present, and the Future
    Author: Liliane Massaad-Massade
    Year: 2020

 

  • Small Interfering RNA From the Lab Discovery to Patients’ Recovery
    Authors: Marie Caillaud, Mévidette El Madani, Liliane Massaad-Massade
    Year: 2020

 

  • Newly Identified LMO3-BORCS5 Fusion Oncogene in Ewing Sarcoma at Relapse Is a Driver of Tumor Progression
    Author: Liliane Massaad-Massade
    Year: 2019

 

  • A Novel Therapeutic Approach to Colorectal Cancer in Diabetes: Role of Metformin and Rapamycin
    Author: Liliane Massaad-Massade
    Year: 2019

 

  • Discovery of New Fusion Transcripts in a Cohort of Pediatric Solid Cancers at Relapse and Relevance for Personalized Medicine
    Author: Liliane Massaad-Massade
    Year: 2019

 

🌟 Conclusion

Dr. Liliane Massade is a beacon of innovation and leadership in molecular biology and targeted therapies. From her academic beginnings in Lebanon to her groundbreaking contributions in France, she has forged a path of excellence that inspires scientists worldwide. With her unparalleled expertise and passion, she continues to redefine the possibilities of modern medicine, leaving an indelible mark on science and humanity.

Janka Jakusova | Allergic rhinitis | Best Researcher Award

Dr. Janka Jakusova | Allergic rhinitis | Best Researcher Award

Dr. Janka Jakusova Jessenius, Faculty of Medicine in Martin, Comenius University in Bratislava,  Slovakia.

Dr. Janka Jakusova is a passionate and accomplished Doctor of General Medicine currently completing her Ph.D. at the Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava. Her research focuses on the cough reflex, particularly in chronic allergic rhinitis models, targeting voltage-gated sodium channels for chronic cough therapy. With extensive experience in clinical and academic settings, she has contributed significantly to respiratory pathophysiology studies, particularly in pediatric patients and COVID-19 impacts. Dr. Jakusova is also a dedicated educator, shaping the next generation of medical professionals. Her scholarly contributions include nine publications, with ongoing research projects that showcase her commitment to advancing medical science.

Profile

Scopus

🌟 Early Academic Pursuits

Janka Jakusova, MD, began her distinguished journey in medicine and research with a passion for understanding human physiology and its intricate mechanisms. As a Doctor of General Medicine, she honed her foundational knowledge at the Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava. Her academic zeal was evident early on, laying a strong groundwork for a career dedicated to advancing medical science.

🩺 Professional Endeavors

Dr. Jakusova is currently in the final year of her full-time Ph.D. studies, where she explores the complexities of the cough reflex in a chronic allergic rhinitis model. In parallel, she serves as a lecturer, sharing her expertise with medical students and fostering their understanding of pathophysiology. Her professional experiences include impactful work at the National Institute for Pediatric Tuberculosis and Respiratory Diseases in Dolný Smokovec and the Infectious Disease Clinic in Ružomberok, where she studied the pediatric cough reflex and the effects of COVID-19, respectively.

🔬 Contributions and Research Focus

A dedicated researcher, Dr. Jakusova’s primary focus is on voltage-gated sodium channels as therapeutic targets for chronic cough, offering promising insights into new treatment approaches. Her scholarly contributions include nine publications in renowned SCI and Scopus-indexed journals. She has successfully completed two research projects and is actively involved in two more, reflecting her unwavering commitment to expanding the boundaries of medical knowledge.

🏆 Accolades and Recognition

Dr. Jakusova’s contributions to medical research have earned her an h-index of 2, signifying her influence in the scientific community. Her work, particularly in pediatric cough studies and the COVID-19 clinical landscape, has been recognized for its innovative approach and practical implications in improving patient care.

🌍 Impact and Influence

As an educator and researcher, Dr. Jakusova impacts both academia and clinical medicine. Her lectures inspire future medical professionals, while her research bridges theoretical knowledge and practical applications. By focusing on underexplored areas such as chronic cough mechanisms, she addresses unmet medical needs and contributes to the global understanding of respiratory diseases.

💡 Legacy and Future Contributions

Janka Jakusova’s vision extends beyond her current achievements. She aims to continue her exploration of respiratory pathophysiology, targeting innovative therapeutic strategies and contributing to the broader medical field. Her dedication to teaching and research ensures a lasting legacy, fostering knowledge and inspiring the next generation of medical professionals.

📚 Lifelong Dedication to Medicine and Research

Dr. Jakusova’s journey exemplifies a life committed to the advancement of medicine. Her efforts in uncovering the nuances of respiratory pathophysiology, combined with her role as an educator, underline her dual impact on science and society. With a promising future ahead, her work is poised to leave an indelible mark on the field of medicine.

📚Publications

  1. Effectiveness of selective NaV1.7 blocker PF-05089771 in reducing cough associated with allergic rhinitis in guinea pigs
    Authors: Jakusova, J., Buday, T., Mokra, D., Plevkova, J., Brozmanova, M.
    Year: 2025

 

  1. Impact of microbial diversity on inflammatory cytokines and respiratory pattern measured in whole-body plethysmography in guinea pig models
    Authors: Buday, T., Brozmanova, M., Jakusova, J., Biringerova, Z., Plevkova, J.
    Year: 2025

 

  1. Advancing cough research: Methodological insights into cough challenge in guinea pig models using double chamber vs whole-body plethysmography
    Authors: Plevkova, J., Jakusova, J., Brozmanova, M., Biringerova, Z., Buday, T.
    Year: 2024

 

  1. Influence of combined voltage-gated sodium channel NaV1.7 and NaV1.8 inhibitors on cough in a guinea pig model
    Authors: Brozmanova, M., Buday, T., Jakusova, J., Melegova, J., Plevkova, J.
    Year: 2023

 

  1. Methods of Cough Assessment and Objectivization
    Authors: Jakusova, J., Brozmanova, M.
    Year: 2023

 

  1. Effect of Selected Music Soundtracks on Cardiac Vagal Control and Complexity Assessed by Heart Rate Variability
    Authors: Parizek, D., Visnovcova, N., Sladicekova, K.H., Ferencova, N., Tonhajzerova, I.
    Year: 2023

 

  1. Measurement of electromagnetic characteristics of BIOMAG – medical device for magnetotherapy | Pomiar właściwości elektromagnetycznych BIOMAG – urządzenia medycznego do magnetoterapii
    Authors: Hamza Sladicekova, K., Misek, J., Radil, R., Alhakim, A., Jakus, J.
    Year: 2023

 

  1. Electromagnetic Fields – Do They Pose a Cardiovascular Risk?
    Authors: Parizek, D., Visnovcova, N., Sladicekova, K.H., Ferencova, N., Tonhajzerova, I.
    Year: 2023

Conclusion

Dr. Jakusova’s dedication to exploring under-researched areas, such as chronic cough mechanisms, highlights her innovative approach to solving real-world medical challenges. Her dual role as a researcher and educator ensures her work has both immediate and lasting impacts on science and society. As she continues her journey, Dr. Jakusova is poised to make groundbreaking contributions to respiratory medicine, solidifying her legacy as a leader in the field.

 

 

Sunita Pokhrel Bhattarai | Cognitive | Best Researcher Award

Dr. Sunita Pokhrel Bhattarai | Cognitive | Best Researcher Award

Dr. Sunita Pokhrel, Bhattarai Ohio State University, United States.

Dr. Sunita Pokhrel Bhattarai, Ph.D., RN, is a distinguished nursing scholar and practitioner with a remarkable academic and professional journey. Her career began with an exceptional academic foundation in nursing, supported by prestigious scholarships. She transitioned seamlessly from clinical excellence in Nepal to advanced research and education in the global arena. Her doctoral research at the University of Rochester, focused on innovative methods for diagnosing acute heart failure, underscores her contributions to cardiovascular nursing. Beyond clinical practice, Sunita has excelled in academia, research coordination, and manuscript review, emphasizing her influence in the global nursing and healthcare community. Her accolades, including diversity and travel grants, reflect her dedication to excellence and equity in healthcare.

Profile

Scholar

🩺 Early Academic Pursuits: A Foundation of Excellence

Sunita Pokhrel Bhattarai, Ph.D., RN, began her academic journey with an unwavering commitment to healthcare and nursing education. From earning her Proficiency Certificate in Nursing on a full government scholarship in Nepal to completing her Bachelor’s in Nursing with a specialization in Community Health, Sunita demonstrated a dedication to academic excellence. Her early research on the knowledge and consequences of teenage marriage in Nepal set the stage for her future pursuits. This strong foundation was further reinforced through her Master’s studies in Emergency and Critical Care Nursing under the Erasmus Mundus Scholarship, where she explored advanced cardiac life support knowledge among critical care nurses.

💼 Professional Endeavors: Leadership in Nursing Practice and Education

Sunita’s professional trajectory reflects a remarkable blend of clinical expertise and academic leadership. She served as a Registered Nurse in Nepal’s premier institutions, including Shahid Gangalal National Heart Centre, where she specialized in cardiac care. Transitioning into academia, she became a Nursing Lecturer at Purbanchan University, imparting her knowledge to future nurses. These roles enriched her understanding of healthcare delivery and education, enabling her to contribute effectively to the global nursing community.

🔬 Contributions to Cardiovascular Research: Bridging Practice and Science

Driven by a passion for advancing cardiovascular care, Sunita’s research focuses on acute heart failure and innovative diagnostic approaches. Her doctoral research at the University of Rochester aimed to estimate left ventricular ejection fraction using ECG, a novel contribution to acute heart failure management. Her involvement in multidisciplinary projects, such as investigating the optimal timing for coronary angiography, highlights her ability to bridge clinical practice and scientific inquiry. Her research not only addresses critical clinical questions but also emphasizes the importance of evidence-based solutions in nursing.

🏆 Accolades and Recognition: Celebrating a Trailblazer

Sunita’s outstanding contributions have been recognized with numerous awards and grants. Notable honors include the Presidential Stronger as One Diversity Award from the University of Rochester and the Ireta Neumann Scholarship for International Nurses. Her achievements underscore her dedication to fostering diversity and excellence in nursing. Travel grants from esteemed organizations like the American Heart Association and the International Society for Computerized Electrocardiology further reflect her active participation in the global research community.

🌍 Impact and Influence: Advancing Global Health Equity

Sunita’s work extends beyond research and practice to address disparities in healthcare delivery. With a keen interest in self-care, implementation science, and healthcare discrepancies, she aims to enhance patient outcomes and equity in access to care. Her contributions as a research lead coordinator and manuscript reviewer illustrate her influence in shaping nursing science. Through mentorship and scholarly collaboration, she continues to inspire the next generation of healthcare professionals.

🧠 Legacy of Expertise: Pioneering Big Data and Applied Statistics

Sunita’s proficiency in big data analysis and applied statistics distinguishes her as a thought leader in nursing research. By leveraging these tools, she has contributed to clinical trials and comprehensive literature reviews that inform evidence-based practice. Her role as an abstract reviewer and researcher underscores her commitment to advancing knowledge in cardiovascular nursing and beyond.

🌟 Future Contributions: A Vision for Transformative Healthcare

With her multifaceted expertise and global perspective, Sunita is poised to drive innovation in healthcare. Her dedication to improving acute heart failure diagnostics, addressing healthcare disparities, and mentoring emerging scholars positions her as a transformative figure in nursing science. Her journey is a testament to the power of perseverance, scholarship, and a passion for improving lives.

📚 Publications

  • Delays in door-to-diuretic time and 1-year mortality among patients with heart failure
    Authors: DJ Dzikowicz, SP Bhattarai, J Ng, AL Zemanek, MG Carey
    Year: 2022

 

  • Signs and Symptoms Clusters Among Patients With Acute Heart Failure: A Correlational Study
    Authors: S Pokhrel Bhattarai, DJ Dzikowicz, MG Carey
    Year: 2023

 

  • Integrative review of electrocardiographic characteristics in patients with reduced, mildly reduced, and preserved heart failure
    Authors: SP Bhattarai, RC Block, Y Xue, DH Rodriguez, RG Tucker, MG Carey
    Year: 2024

 

  • Knowledge and practices on prevention of coronary artery diseases in Nepalese community: A cross-sectional from five different cities in Nepal
    Authors: SP Bhattarai, P Neupane
    Year: 2018

 

  • Estimating Ejection Fraction from the 12 Lead ECG among Patients with Acute Heart Failure
    Authors: SP Bhattarai, DJ Dzikowicz, Y Xue, R Block, RG Tucker, S Bhandari, …
    Year: 2024

 

  • Door-to-Diuretic Time is related to length of hospital stay independent of diuretic dose among acute decompensated heart failure patients
    Authors: DJ Dzikowicz, M Aktas, SP Bhattarai, L Chen, MG Carey
    Year: 2025

 

  • Estimating very low ejection fraction from the 12 Lead ECG among patients with acute heart failure
    Authors: SP Bhattarai, DJ Dzikowicz, Y Xue, R Block, RG Tucker, S Bhandari, …
    Year: 2025

 

  • Association Between Serum Albumin and the Length of Hospital Stay Among Patients With Acute Heart Failure
    Authors: S Pokhrel Bhattarai, DJ Dzikowicz, MG Carey
    Year: 2025

 

  • Estimating ejection fraction from the 12 lead ECG in acute heart failure
    Authors: SB Pokhrel, DJ Dzikowicz, S Bhandari, VE Boulware, MG Carey
    Year: 2024

 

  • Interaction Between Door To Diuretic Time And Dosing As A Predictor Of Mortality And Readmission
    Authors: D Dzikowicz, SP Bhattarai, L Chen, MG Carey
    Year: 2024

 

Conclusion

Dr. Sunita Pokhrel Bhattarai’s journey illustrates the power of knowledge, resilience, and a commitment to improving healthcare. By integrating clinical expertise, innovative research, and global collaboration, she has advanced the field of cardiovascular nursing and inspired future generations. Her ongoing work promises to bridge gaps in healthcare delivery, enhance patient outcomes, and drive transformative change in nursing science. Sunita’s legacy is one of impact, innovation, and an enduring dedication to the betterment of global health.

Maria Habib | Optimization | Best Researcher Award

Ms. Maria Habib | Optimization | Best Researcher Award

Ms. Maria Habib, Granada University/ Samsung R&D (SRJO), Jordan.

Maria Habib is a distinguished researcher and AI engineer whose journey spans academia and industry. With a strong foundation in Computer Engineering, she advanced her expertise through a Master’s in Web Intelligence and is currently pursuing a Ph.D. in Information Technology and Communication. Maria’s professional endeavors include leading AI projects at Samsung R&D, transforming telehealth services at Altibbi, and contributing to bioinformatics at McGill University. Her research focuses on artificial intelligence, machine learning, evolutionary algorithms, and NLP, producing innovative solutions and influential publications. Her work has significantly impacted telemedicine, educational data mining, and speech technologies, establishing her as a transformative force in AI.

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Early Academic Pursuits 🎓

Maria Habib embarked on her academic journey with a robust foundation in Computer Engineering, earning her Bachelor’s degree from the University of Jordan in 2014. Demonstrating early promise, she excelled in her Master’s program in Web Intelligence at the prestigious King Abdullah II School for Information Technology, attaining an outstanding GPA of 3.91/4. Her passion for leveraging technology to address real-world challenges was evident from the outset, as she explored advanced concepts in information systems and web technologies. Maria is currently pursuing her Ph.D. in Information Technology and Communication at Granada University, Spain, where she continues to delve into cutting-edge AI research.

Professional Endeavors 💼

Maria’s career trajectory reflects a seamless blend of academic rigor and industry innovation. At Samsung R&D Institute in Jordan, she leads AI projects focusing on speech recognition and natural language processing, showcasing her prowess in automation and advanced search systems. Prior to this, Maria honed her skills at Altibbi, where she developed machine learning and deep learning models to revolutionize telehealth services. Her expertise spans diverse roles, from Python development for logistics platforms at Polares LLC to teaching Computer Science at ADS School. Each position has deepened her technical acumen and solidified her reputation as a versatile problem-solver.

Contributions and Research Focus 🔬

Maria’s research centers on artificial intelligence, machine learning, and evolutionary algorithms, emphasizing their transformative potential in healthcare, education, and NLP. Her collaborations with renowned academics like Prof. Hossam Faris and Dr. Ghaith Rabadi have resulted in influential publications in prestigious journals. Her work extends to bioinformatics, where she contributed to microbiome data visualization during her tenure as a Graduate Research Trainee at McGill University. As a member of the Evo-ML research group, Maria explores innovative solutions that bridge academia and industry, reinforcing her commitment to advancing AI for societal benefit.

Accolades and Recognition 🏆

Maria’s dedication to excellence has not gone unnoticed. Her stellar academic performance earned her accolades throughout her educational journey, culminating in a Master’s GPA of 3.91/4.0. Her professional roles have been marked by commendations for innovation and leadership, particularly at Samsung R&D and Altibbi. References from distinguished mentors like Prof. Ibrahim Aljarah and Prof. Jiangou Xia underscore the high regard in which she is held within the academic and professional communities.

Impact and Influence 🌍

Through her work in AI, Maria has significantly impacted fields such as telemedicine, educational data mining, and speech understanding. Her contributions to Altibbi transformed telehealth services, making them more accessible and efficient. Her teaching and mentorship roles have inspired students and peers alike, fostering a new generation of tech enthusiasts. Her initiatives in AI automation and optimization continue to resonate within the global technology landscape.

Legacy and Future Contributions 🌟

Maria’s journey is far from over. As an AI Project Lead and researcher, she is poised to shape the future of speech and language technologies. Her ongoing Ph.D. research promises groundbreaking insights into AI and communication systems. With a clear vision for the future, Maria aspires to bridge the gap between research and real-world applications, ensuring her legacy as a pioneer in computational innovation.

📚 Publications

  1. Title: Intelligent detection of hate speech in Arabic social network: A machine learning approach
    Authors: I. Aljarah, M. Habib, N. Hijazi, H. Faris, R. Qaddoura, B. Hammo, …
    Year: 2021

 

  1. Title: A dynamic locality multi-objective salp swarm algorithm for feature selection
    Authors: I. Aljarah, M. Habib, H. Faris, N. Al-Madi, A.A. Heidari, M. Mafarja, …
    Year: 2020

 

  1. Title: Augmented whale feature selection for IoT attacks: Structure, analysis, and applications
    Authors: M. Mafarja, A.A. Heidari, M. Habib, H. Faris, T. Thaher, I. Aljarah
    Year: 2020

 

  1. Title: Android ransomware detection based on a hybrid evolutionary approach in the context of highly imbalanced data
    Authors: I. Almomani, R. Qaddoura, M. Habib, S. Alsoghyer, A. Al Khayer, I. Aljarah, …
    Year: 2021

 

  1. Title: Evolutionary inspired approach for mental stress detection using EEG signal
    Authors: L.D. Sharma, V.K. Bohat, M. Habib, A.Z. Ala’M, H. Faris, I. Aljarah
    Year: 2022

 

  1. Title: Hate Speech Detection using Word Embedding and Deep Learning in the Arabic Language Context
    Authors: H. Faris, I. Aljarah, M. Habib, P.A. Castillo
    Year: 2020

 

  1. Title: An intelligent evolutionary extreme gradient boosting algorithm development for modeling scour depths under submerged weir
    Authors: H. Tao, M. Habib, I. Aljarah, H. Faris, H.A. Afan, Z.M. Yaseen
    Year: 2021

 

  1. Title: Optimizing extreme learning machines using chains of salps for efficient android ransomware detection
    Authors: H. Faris, M. Habib, I. Almomani, M. Eshtay, I. Aljarah
    Year: 2020

 

  1. Title: Salp chain-based optimization of support vector machines and feature weighting for medical diagnostic information systems
    Authors: A.M. Al-Zoubi, A.A. Heidari, M. Habib, H. Faris, I. Aljarah, M.A. Hassonah
    Year: 2020

 

 

Conclusion

Maria Habib’s career exemplifies the intersection of technical expertise and societal impact. Through her leadership and innovative research, she has contributed to advancements in healthcare, communication, and education. Her commitment to bridging research and application ensures her legacy as a pioneer in AI. Maria’s inspiring journey underscores the power of determination and innovation, positioning her as a role model in the global technology community.

Samira Jafari | Brain Mapping | Best Researcher Award

Dr. Samira Jafari | Brain Mapping | Best Researcher Award

Dr Samira Jafari, Kerman university of medical sciences, Iran.

Dr. Samira Jafari, a distinguished Ph.D. in Biostatistics at Kerman University of Medical Sciences, is a leading researcher in biostatistics, machine learning methods, and meta-analysis. With 11 research projects and 11 journal publications in SCI and Scopus-indexed journals, she has made significant contributions to healthcare research, focusing on data-driven solutions. Her work in integrating machine learning with biostatistical models aims to enhance health data analysis, with the potential for improving disease prediction, public health policies, and medical practices.

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Early Academic Pursuits: The Foundation of Expertise 📚

Dr. Jafari’s academic journey began with a strong foundation in biostatistics, where she honed her analytical skills and developed a passion for understanding the intricacies of data. During her studies, she was captivated by the potential of machine learning to transform data analysis in healthcare, laying the groundwork for her future endeavors. Her early academic pursuits focused on mastering statistical models and computational techniques, which would become the bedrock of her later research.

Professional Endeavors: Shaping Research Landscape 🧑‍🔬

Since completing her Ph.D., Dr. Jafari has become a key figure in advancing biostatistics research, particularly through her exploration of machine learning applications. At Kerman University of Medical Sciences, she has led numerous research projects, with a total of 11 completed and ongoing studies. Her expertise has contributed to groundbreaking work in applying biostatistics and machine learning methods to analyze large-scale healthcare data. Dr. Jafari’s research provides essential insights that enhance the understanding of disease patterns and contribute to better health outcomes.

Contributions and Research Focus: Bridging Knowledge and Practice 🧠

Dr. Jafari’s research contributions are particularly notable in the integration of machine learning algorithms with biostatistics to improve health data interpretation. Her work includes innovative meta-analytic methods to synthesize complex data and uncover underlying patterns that inform healthcare practices. By combining machine learning with statistical models, she has been able to provide robust solutions for various medical and epidemiological studies. With 11 journal publications in top-tier journals like SCI and Scopus, her research has had a significant impact on advancing statistical methods in biostatistics.

Accolades and Recognition: Scholarly Achievements 🏆

Dr. Jafari’s scholarly achievements have not gone unnoticed. Her work has earned recognition through a citation index of 2, reflecting her contributions to the academic community. Despite the limited citations, her research is highly regarded for its innovative approach to statistical modeling and its potential applications in the field of biostatistics. She has made a lasting impression through her academic rigor, innovative methods, and dedication to enhancing the quality of healthcare research.

Impact and Influence: Leading the Way in Quantitative Healthcare Research 🌍

Dr. Jafari’s work in biostatistics and machine learning has influenced both academic research and practical applications in healthcare. Her innovative approaches to analyzing and interpreting health data have the potential to change how public health research is conducted, improving the accuracy and efficacy of healthcare models. The widespread application of her research is likely to influence future healthcare policy and contribute to the development of more precise, data-driven medical treatments.

Legacy and Future Contributions: A Path to Continued Innovation 🔮

Dr. Jafari’s research journey is far from over. With numerous ongoing projects, she is poised to continue contributing to the field of biostatistics, machine learning, and meta-analysis. As a dedicated researcher, her future work promises to explore new frontiers in data analysis, helping to bridge the gap between complex statistical methods and practical healthcare applications. Dr. Jafari’s contributions will undoubtedly have a lasting impact on the way we analyze medical data, shaping the future of healthcare and biostatistics for years to come.

📚 Publications

  • Title: The best drug supplement for obesity treatment: a systematic review and network meta-analysis
    Authors: N Salari, S Jafari, N Darvishi, E Valipour, M Mohammadi, K Mansouri, …
    Year: 2021

 

  • Title: Classifying patients with lumbar disc herniation and exploring the most effective risk factors for this disease
    Authors: S Jafari, T Dehesh, F Iranmanesh
    Year: 2019

 

  • Title: Diagnosis of borderline personality disorder based on Cyberball social exclusion task and resting-state fMRI: using machine learning approach as an auxiliary tool
    Authors: S Jafari, A Almasi, H Sharini, S Heydari, N Salari
    Year: 2023

 

  • Title: The best surgical treatment for cervical radiculopathy: a systematic review and network meta-analysis
    Authors: A Almasi, S Jafari, L Solouki, N Darvishi
    Year: 2023

 

  • Title: Radiomics-based machine learning for automated detection of Pneumothorax in CT scans
    Authors: H Alimiri Dehbaghi, K Khoshgard, H Sharini, S Jafari Khairabadi, …
    Year: 2024

 

  • Title: Diagnosis of traumatic liver injury on computed tomography using machine learning algorithms and radiomics features: The role of artificial intelligence for rapid diagnosis in …
    Authors: HA Dehbaghi, K Khoshgard, H Sharini, SJ Khairabadi
    Year: 2024

 

  • Title: A assessment of the effects of parental age on the development of autism in children: a systematic review and a meta-analysis
    Authors: T Dehesh, MA Mosleh-Shirazi, S Jafari, E Abolhadi, P Dehesh
    Year: 2024

 

Conclusion

Dr. Samira Jafari stands as a trailblazer in the field of biostatistics and machine learning, making invaluable contributions to healthcare research. Through her innovative integration of machine learning with biostatistical models, she has advanced our understanding of complex health data, paving the way for more accurate predictions and improved healthcare outcomes. With her extensive research experience and a clear commitment to bridging data analysis with real-world medical applications, Dr. Jafari is set to leave a lasting legacy in both academic and healthcare sectors.

Mamunur Roshid | Nonlinear Science | Best Researcher Award

Mamunur Roshid | Nonlinear Science | Best Researcher Award

Mr. Md. Mamunur Roshid, Hamdard University Bangladesh, Bangladesh.

Md. Mamunur Roshid is a dedicated mathematician, educator, and researcher whose work spans bifurcation analysis, nonlinear oscillations, soliton theory, and biomathematics. Currently a Lecturer at Hamdard University Bangladesh and a Ph.D. candidate at BUET, he has contributed significantly to mathematical research, with over 515 Google Scholar citations and a strong presence as a peer reviewer for leading journals. Passionate about teaching, he has mentored multiple undergraduate students and continues to inspire the next generation while pushing the boundaries of mathematical understanding.

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📚 Early Academic Pursuits

Md. Mamunur Roshid’s passion for mathematics began with his academic journey in Bangladesh. His commitment to the field was evident through his exceptional projects during his undergraduate studies, where he delved into the “Exact and Solitary Wave Solution of Nonlinear Evolution Equation via Modified Simple Equation Method.” This foundation was further solidified during his Master’s research, which focused on solving nonlinear models using advanced mathematical techniques. Now pursuing a Ph.D. at the Bangladesh University of Engineering and Technology, his thesis explores “Bifurcation Analysis and Various Dynamics of Soliton Solutions of Nonlinear Fractional Models,” marking another milestone in his academic journey.

Professional Endeavors

Currently serving as a Lecturer in the Department of Mathematics at Hamdard University Bangladesh since March 2022, Md. Mamunur Roshid is dedicated to inspiring and educating future mathematicians. His professional journey also includes a stint as a Research Assistant on the “AUST Internal Research Grant” project. These roles have allowed him to merge teaching with active research, creating a dynamic environment where knowledge is both shared and expanded.

🔬 Contributions and Research Focus

Md. Mamunur Roshid’s research interests span a diverse range of topics, including bifurcation analysis, chaotic systems, nonlinear oscillations, fractional derivatives, soliton theory, and mathematical modeling in finance and biomathematics. His work has produced significant insights into the behavior of nonlinear systems, exact traveling wave solutions, and fractional-order dynamics, contributing to the broader understanding of mathematical physics and its applications.

🏆 Accolades and Recognition

With over 515 citations, a Google Scholar h-index of 16, and an i10-index of 19, Md. Mamunur Roshid’s scholarly impact is evident. He has earned recognition as a peer reviewer for renowned journals like Nonlinear Dynamics, Scientific Reports, and Optical Quantum Electronics. His dedication to ensuring academic excellence in these publications underscores his expertise and contributions to the global mathematical community.

🌍 Impact and Influence

Through his teaching and supervision, Md. Mamunur Roshid has mentored seven undergraduate students, guiding them in projects that explore advanced mathematical theories and applications. These students, including Mst. Sahana Hasan, Toky Iman, and Arifa Akter Ripa, represent the future of mathematical research, nurtured under his thoughtful guidance. His commitment to fostering curiosity and critical thinking has left a lasting impression on his students and peers alike.

💡 Legacy and Future Contributions

Md. Mamunur Roshid’s ongoing research into nonlinear fractional models and their dynamic solutions promises to address critical questions in mathematical physics and applied mathematics. His expertise in bifurcation analysis and soliton theory is expected to continue influencing fields such as engineering, finance, and biomathematics, leaving a legacy of innovation and interdisciplinary collaboration.

✨ Inspiring the Next Generation

Driven by a deep love for mathematics, Md. Mamunur Roshid aspires to instill the same enthusiasm in his students. His vision for the future includes advancing mathematical knowledge while motivating the younger generation to view mathematics as a powerful tool for solving complex problems. Through his efforts, he continues to create a vibrant academic and research environment that bridges theory and application, shaping the future of mathematics.

📚 Publications

  • Exact and explicit traveling wave solutions to two nonlinear evolution equations which describe incompressible viscoelastic Kelvin-Voigt fluid
    Authors: MM Roshid, HO Roshid
    Year: 2018

 

  • New solitary wave in shallow water, plasma and ion acoustic plasma via the GZK-BBM equation and the RLW equation
    Authors: HO Roshid, MM Roshid, N Rahman, MR Pervin
    Year: 2017

 

  • Lump, interaction of lump and kink and solitonic solution of nonlinear evolution equation which describe incompressible viscoelastic Kelvin–Voigt fluid
    Authors: MM Roshid, T Bairagi, MM Rahman
    Year: 2022

 

  • Dynamical simulation of wave solutions for the M-fractional Lonngren-wave equation using two distinct methods
    Authors: MM Roshid, MM Rahman, MH Bashar, MM Hossain, MA Mannaf
    Year: 2023

 

  • Kinky periodic pulse and interaction of bell wave with kink pulse wave propagation in nerve fibers and wall motion in liquid crystals
    Authors: MM Roshid, MZ Ali, H Rezazadeh
    Year: 2020

 

  • Dynamical interaction of solitary, periodic, rogue type wave solutions and multi-soliton solutions of the nonlinear models
    Authors: MM Roshid, A Abdeljabbar, A Aldurayhim, MM Rahman, FS Alshammari
    Year: 2022

 

  • New solitonic and rogue wave solutions of a Klein–Gordon equation with quadratic nonlinearity
    Authors: MM Roshid, MF Karim, AK Azad, MM Rahman, T Sultana
    Year: 2021

 

  • Breather Wave and Kinky Periodic Wave Solutions of One-Dimensional Oskolkov Equation
    Authors: M Roshid, H Bashar
    Year: 2019

 

  • Dynamical analysis of optical soliton solutions for CGL equation with Kerr law nonlinearity in classical, truncated M-fractional derivative, beta fractional derivative, and …
    Authors: AK Chakrabarty, MM Roshid, MM Rahaman, T Abdeljawad, MS Osman
    Year: 2024

 

  • Dynamical structure of optical soliton solutions for M− fractional paraxial wave equation by using unified technique
    Authors: MM Roshid, M Uddin, G Mostafa
    Year: 2023

 

 

Conclusion

Md. Mamunur Roshid embodies a harmonious blend of academic excellence, innovative research, and impactful teaching. His contributions to the field of mathematics, particularly in nonlinear dynamics and fractional models, have established him as a respected figure in the global academic community. Through his research, teaching, and mentorship, he continues to inspire the next generation of mathematicians while advancing knowledge in his field. His dedication to fostering curiosity and critical thinking ensures a lasting legacy, with far-reaching implications for both theoretical and applied mathematics.