Prof. Baoman Li, China Medical University, China.
Professor Baoman Li stands at the forefront of contemporary neuroscience and pharmacology, merging deep academic knowledge with impactful translational research. From his foundational training at China Medical University to his postdoctoral work in the United States, he has consistently demonstrated excellence in exploring the physiological and molecular mechanisms of the central nervous system. Currently a Professor and Department Director, his work has revealed novel insights into cerebrospinal fluid transport, neuronal excitability regulation, and bipolar disorder modeling. These discoveries have been featured in top-tier journals such as PNAS, Cell Metabolism, and Molecular Psychiatry.
Profile
Scopus
🎓 Early Academic Pursuits
Baoman Li’s journey into the world of biomedical science began with a strong academic foundation. He pursued his Ph.D. in Medical Pharmacology at China Medical University, where he cultivated a keen interest in the intersection of neuroscience, pharmacology, and toxicology. His early research provided him with an in-depth understanding of neural mechanisms and laid the groundwork for his future innovations. Eager to expand his international experience, he furthered his postdoctoral research at the University of Rochester Medical Center (USA) from 2013 to 2014, where he deepened his expertise in neuropharmacological research.
🧪 Professional Endeavors
Currently serving as a Professor and Department Director at the Forensic Analytical Toxicology Department of China Medical University, Professor Li leads a dynamic team of researchers and scholars. His leadership has not only enhanced academic standards within the department but has also positioned it as a center of excellence in the field of neuroglial research and forensic toxicology. His multidisciplinary approach merges analytical science with neuroscience, significantly advancing our understanding of central nervous system (CNS) function and dysfunction.
🧠 Contributions and Research Focus
Professor Li’s research focuses on cutting-edge discoveries related to neural mechanisms, cerebrospinal fluid dynamics, and neuropsychiatric disorders. One of his landmark studies, published in PNAS (2024), identified ependymal cell-mediated cerebrospinal fluid transport from the CNS to peripheral organs, revealing a critical physiological communication pathway. In another pivotal contribution in Cell Metabolism (2025), he elucidated the role of the NE-FFA-Na⁺/K⁺-ATPase pathway in regulating neuronal hyperexcitability and behavioral arousal. Moreover, his groundbreaking development of a circadian disruption-induced manic mouse model for bipolar disorder research (published in Molecular Psychiatry, 2023) has provided a valuable tool for studying mood disorders and developing new therapeutic approaches.
📚 Academic Publications and Editorial Work
With an impressive academic portfolio, Professor Li has authored and edited three influential books centered on neuroglial science, expanding the literature in this specialized domain. His published works include notable titles with ISBNs: 978-7-117-34321-3, 978-3-030-77375-5, and 978-2-88963-497-2. These contributions serve as essential resources for both emerging and seasoned neuroscientists, offering detailed insights into glial biology, neurochemical interactions, and translational research.
🏅 Accolades and Recognition
Professor Li’s scholarly excellence is widely recognized, as reflected in his H-index of 34 and a total citation count of 3,530 according to Web of Science. His ability to consistently produce high-impact research has made him a respected voice in neuroscience and pharmacology. He has successfully led eight research projects funded by prestigious bodies such as the Natural Science Foundation of China and the Ministry of Education, while also currently heading two additional projects supported by the provincial science foundation.
🤝 Industry and Consultancy Impact
Beyond academic circles, Professor Li has extended his expertise into practical applications through four consultancy projects, bridging the gap between research and real-world forensic or pharmaceutical needs. His ability to translate complex neuropharmacological findings into actionable insights for the industry underscores his role as not only a theorist but also a problem-solver and innovator.
🔬 Legacy and Future Contributions
As a scientist, educator, and leader, Professor Baoman Li continues to shape the future of neuroscience and pharmacological toxicology. His ongoing research and collaborative efforts are expected to yield further breakthroughs in understanding brain-behavior relationships and disease mechanisms. With a legacy already marked by innovation and impact, his future contributions promise to enhance diagnostics, treatments, and preventive strategies for neurological and psychiatric disorders. His commitment to mentoring young scholars and editing academic literature ensures that his influence will resonate across generations of researchers to come.
Publication
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Title: Cerebrospinal Fluid Enters Peripheral Organs by Spinal Nerves Supporting Brain–Body Volume Transmission
Authors: Li, Baoman; Xia, Maosheng; Harkany, Tibor; Verkhratsky, Alexei N.
Year: Not specified (likely 2024 or 2025)
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Title: Anti-seizure effects of norepinephrine-induced free fatty acid release
Authors: Li, Baoman; Sun, Qian; Ding, Fengfei; Smith, Nathan A.; Nedergaard, Maiken
Year: 2025
Journal: Cell Metabolism
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Title: Major depressive disorder: hypothesis, mechanism, prevention and treatment
Authors: Cui, Lulu; Li, Shu; Wang, Siman; Xia, Maosheng; Li, Baoman
Year: Not specified (likely 2024 or 2025)
Type: Review (Open access)
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Title: The periaxonal space as a conduit for cerebrospinal fluid flow to peripheral organs
Authors: Li, Xinyu; Wang, Siman; Zhang, Dianjun; Xia, Maosheng; Li, Baoman
Year: 2024
Journal: Proceedings of the National Academy of Sciences of the USA (Open access)
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Title: Dexmedetomidine improves the circulatory dysfunction of the glymphatic system induced by sevoflurane through the PI3K/AKT/ΔFosB/AQP4 pathway in young mice
Authors: Wang, Shuying; Yu, Xiaojin; Cheng, Lili; Lu, Yan; Wu, Xu
Year: 2024
Journal: Cell Death and Disease (Open access)
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Title: Ketamine administration causes cognitive impairment by destroying the circulation function of the glymphatic system
Authors: Wu, Xue; Wen, Gehua; Yan, Lei; Lu, Yan; Wu, Xu
Year: 2024
Journal: Biomedicine and Pharmacotherapy (Open access)
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Title: Correction to: Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model
Authors: Wen, Gehua; Zhan, Xiaoni; Xu, Xiaoming; Lu, Yan; Wu, Xu
Year: 2024
Journal: Molecular Neurobiology (Erratum, Open access)
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Title: Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model
Authors: Wen, Gehua; Zhan, Xiaoni; Xu, Xiaoming; Lu, Yan; Wu, Xu
Year: 2024
Journal: Molecular Neurobiology
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Title: Trace metals and astrocytes physiology and pathophysiology
Authors: Li, Baoman; Yu, Weiyang; Verkhratsky, Alexei N.
Year: 2024
Journal: Cell Calcium
Conclusion:
Dr. Baoman Li is a strong and deserving candidate for the Best Researcher Award. His innovative research, publication in high-impact journals, and interdisciplinary contributions demonstrate excellence and sustained scientific productivity. While he can enhance his visibility and further define his leadership role, his current achievements are more than sufficient to merit this prestigious recognition.