Dr. Lin Xiao | Institute for Brain Research and Rehabilitation | China
Dr. Lin Xiao is a distinguished Professor of Neuroscience at the Institute for Brain Research and Rehabilitation, South China Normal University, whose pioneering research has significantly advanced understanding of oligodendrocyte biology and myelin plasticity. His work elucidates the mechanisms by which adaptive myelination contributes to motor learning and memory, proposing a novel “biphasic plasticity model” that distinguishes distinct phases of learning and consolidation. Dr. Xiao’s research has been published in leading journals including Nature Neuroscience, Science, Nature Communications, and Advanced Science, collectively garnering over 2,800 citations and an h-index of 28, with approximately 20 peer-reviewed articles. His landmark paper in Nature Neuroscience has become a classic reference with over 500 citations, demonstrating substantial influence in the field. He has led multiple projects funded by the National Natural Science Foundation of China, including completed and ongoing studies, and established major collaborations with institutions such as University College London. His research areas include glial–neuron interactions, mechanisms of remyelination, neurodevelopmental disorders such as autism, and psychiatric disorders including depression. These contributions have been recognized with national awards and have opened promising avenues for therapeutic strategies in demyelinating and cognitive disorders.
Featured Publications
Marques, S., Zeisel, A., Codeluppi, S., Van Bruggen, D., Mendanha Falcão, A., et al. (2016). Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system. Science, 352(6291), 1326–1329.
Xiao, L., Ohayon, D., McKenzie, I. A., Sinclair-Wilson, A., Wright, J. L., Fudge, A. D., et al. (2016). Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning. Nature Neuroscience, 19(9), 1210–1217.
Liu, S., Yu, M., He, Y., Xiao, L., Wang, F., Song, C., Sun, S., Ling, C., & Xu, Z. (2008). Melittin prevents liver cancer cell metastasis through inhibition of the Rac1‐dependent pathway. Hepatology, 47(6), 1964–1973.
Li, C., Xiao, L., Liu, X., Yang, W., Shen, W., Hu, C., Yang, G., & He, C. (2013). A functional role of NMDA receptor in regulating the differentiation of oligodendrocyte precursor cells and remyelination. Glia, 61(5), 732–749.
Feng, P. A. N. (2003). Fast mode decision for intra prediction. JVT-G013, March 2003.
Li, Y. X., Ding, S. J., Xiao, L., Guo, W., & Zhan, Q. (2008). Desferoxamine preconditioning protects against cerebral ischemia in rats by inducing expressions of hypoxia inducible factor 1α and erythropoietin. Neuroscience Bulletin, 24(2), 89–95.