Assist. Prof. Dr. Yen-Chein Lai | Developmental Neuroscience | Research Excellence Award
Assist. Prof. Dr. Yen-Chein Lai | Chung Shan Medical University | Taiwan
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Dr. Hendry Ramly is a clinician–researcher with advanced training in general medicine, cardiology, and intensive care medicine, and a focused academic interest in non-traumatic out-of-hospital cardiac arrest and post-resuscitation care. His research is directly informed by frontline clinical practice across acute medicine, ICU, and cardiology, where he manages critically ill patients following cardiac arrest. Dr. Ramly’s primary research examines cardiovascular management strategies after return of spontaneous circulation, with particular emphasis on haemodynamic stabilisation, coronary pathology, and the timing and utility of urgent coronary angiography. Neurological outcomes are included as standard clinical endpoints, while the central focus remains on cardiovascular determinants of survival and in-hospital mortality. He is lead author of a retrospective observational cohort study published in Heart, Lung and Circulation (2025), evaluating outcomes of non-traumatic out-of-hospital cardiac arrest at a tertiary centre. His additional audit work includes thoracic surgical outcomes, geriatric referral pathways, and procedural adequacy in respiratory medicine. Through clinically driven research and multidisciplinary collaboration, Dr. Ramly aims to refine evidence-based pathways that improve survival, decision-making, and quality of care for patients following cardiac arrest.
Adil EL Housseini is a dedicated PhD candidate in biology at Ibn Zohr University, Faculty of Sciences of Agadir, specializing in toxicology, biochemistry, and the molecular characterization of scorpion venoms. His doctoral research explores the biochemical composition, ecotoxicity, and pathophysiological mechanisms of venoms from selected Buthid species, with a particular focus on developing novel therapeutic strategies for scorpion envenomation. Adil has contributed to the scientific community through peer-reviewed publications and authored book chapters spanning biomedical polymers, chitosan-based therapeutic applications, radioprotective biomaterials, and neurobiological insights into astrocyte function. His work on the kinetics of brain oxidative stress following scorpion envenomation highlights his strong command of experimental toxicology and neurobiochemical analysis. With an h-index of 1, two indexed documents, and two citations, he continues to build a research profile grounded in rigorous experimentation and interdisciplinary scientific inquiry. Adil’s skills include venom biochemistry, laboratory toxicology, data interpretation, and scientific writing, supported by strong language proficiency in Arabic, French, and English. His commitment to advancing knowledge in venom toxicology and biomedical sciences positions him as a promising emerging researcher contributing to both fundamental understanding and applied therapeutic innovation.
Ait Hamdan, Y., Rhazi, M., El-Mansoury, B., Kabdy, H., Oukhrib, M., Ait Baba, A., … (2024). Astrocytes functions and their involvement in brain injury: A focus on the biomaterials’ role in mitigating traumatic brain injury. In Physiology and Function of Glial Cells in Health and Disease (pp. 145–163).
Mabsor-Zgandaoui, S., Rachmoune, K., Aftais, I., Elamrani, F. E., Amradi, I., … (2026). Biomedical polymers: Foundations and future innovations in medicine. In Biomedical Applications and Toxicity of Polymers, Nanoparticles
Ait Hamdan, Y., Armadi, I., Elamrani, F. E., Mekouar, M., El Housseini, A., … (2026). Therapeutic implications of chitosan and its derivatives: Focus on cancer treatment. In Biomedical Applications and Toxicity of Polymers, Nanoparticles
Rachmoune, K., Mabsor-Zgandaoui, S., El Housseini, A., Ait Hamdan, Y., … (2026). Radioprotective effects of chitosan polysaccharides and biomedical applications. In Biomedical Applications and Toxicity of Polymers, Nanoparticles
Armadi, I., Elouali, S., Abana, A., El Housseini, A., Loqman, S., & Belbachir, A. (2025). Overview of biomaterials classification, properties, and biomedical applications. In Innovations and Applications of Advanced Biomaterials in Healthcare
Professor Hui Gan is a distinguished researcher at Chongqing Medical University, serving as a master’s supervisor, associate research fellow, and Assistant to the Dean of the School of Basic Medical Sciences, where she also leads the Department of Pathophysiology in an acting capacity. Her research primarily focuses on neuroinflammation, microglial regulation, and inflammasome-mediated injury following cerebral hemorrhage, with significant contributions to understanding TRIM21-mediated mechanisms and microglial transcriptional pathways such as c-MAF–NLRP3 signaling. She has secured multiple competitive national and regional research grants supporting investigations into inflammasome activation, microcirculatory dysfunction, and post-hemorrhagic inflammatory injury. Professor Gan has received notable recognitions, including awards for early-career excellence and contributions to microcirculation research. She plays an active role in professional societies as a committee member of the Microcirculation Committee of the Chinese Society of Pathophysiology and a young committee member of the Translational Medicine Committee of the Chinese Society of Microcirculation, contributing to academic development in basic and translational medical sciences. Her scholarly output includes 18 documents, with 196 citations across 175 citing documents, reflecting a solid research impact supported by an h-index of 8. Through her scientific leadership and innovative research, she continues to advance understanding of inflammatory mechanisms in neurological injury.
Gan, H., Gan, H.-Y., Zhang, M., Duan, Y., Palahati, A., He, Q., Tan, J., Li, Y., Zhai, X., & Zhao, J. (2025). Microglial NFAT5 aggravates neuroinflammation via mediating NLRP6 inflammasome in experimental ischemic stroke. Genes and Diseases, 12(6),
Li, Z., Han, Y., Liu, J.-L., Zhang, X.-Y., Shen, X., Guo, Z.-H., Yin, H., Duo, H., & Fu, Y. (2025). High diversity of Piroplasm species carried by ticks from Qinghai, China. Acta Tropica, 250, 107907.
Fu, Y., Zhang, X., Li, Z., Shi, Z., Ma, X., Meng, R., Zhang, Q., Zhao, C., Guo, S., Ma, W., et al. (2023, November 23). Emerging Echinococcus shiquicus infection of Asian badgers in the Qinghai–Tibetan Plateau. Transboundary and Emerging Diseases, 2023, 6874033.
Fu, Y., Zhang, X., Li, Z., Meng, R., Duo, H., Shen, X., Ma, Y., & Guo, Z. (2023, July). Identification and prevalence of fluke infection in yak and Tibetan sheep around Qinghai Lake, China. Parasitology Research.
Zhang, X., Jian, Y., Li, Z., Duo, H., Guo, Z., & Fu, Y. (2023, February 25). Optimization of single-tube nested PCR for the detection of Echinococcus spp. Experimental Parasitology, 246, 108358.
Liu, J., Zhao, S., Li, Z., Zhang, Z., Zhao, B., Guan, G., Yin, H., & Luo, J. (2023, February 23). Activation of telomerase activity and telomere elongation of host cells by Theileria annulata infection. Frontiers in Microbiology, 14, 1123456.
Camargo Ortega, G., Falk, S., Johansson, P. A., Peyre, E., Broix, L., Sahu, S. K., … (2019). The centrosome protein AKNA regulates neurogenesis via microtubule organization. Nature, 567(7746), 113–117.
Zaidi, D., Chinnappa, K., & Francis, F. (2022). Primary cilia influence progenitor function during cortical development. Cells, 11(18), 2895.
Chinnappa, K., Cárdenas, A., Prieto-Colomina, A., Villalba, A., … (2022). Secondary loss of miR-3607 reduced cortical progenitor amplification during rodent evolution. Science Advances, 8(2), eabj4010.
Prieto-Colomina, A., Fernández, V., Chinnappa, K., & Borrell, V. (2021). MiRNAs in early brain development and pediatric cancer: At the intersection between healthy and diseased embryonic development. BioEssays, 43(7), 2100073.
Chatterjee, A., Chinnappa, K., Ramanan, N., & Mani, S. (2018). Centrosome inheritance does not regulate cell fate in granule neuron progenitors of the developing cerebellum. The Cerebellum, 17(5), 685–691.
Zaidi, D., Chinnappa, K., Yigit, B. N., Viola, V., Cifuentes-Diaz, C., Jabali, A., … (2024). Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia. Journal of Cell Biology, 223(12), e202310157.
Chinnappa, K., Márquez-Galera, Á., Prieto-Colomina, A., Nomura, Y., … (2019). MIR3607 regulates cerebral cortex development via activation of Wnt/βCat signaling. bioRxiv, 729939.
Chinnappa, K., Ballorin, F., & Francis, F. (2025). Fundamental Neurochemistry Review: Sphingolipids and ceramides in brain development. Journal of Neurochemistry, 169(10), e70262.
(2025). Effects of exposure to air pollution and cold weather on acute myocardial infarction mortality. Atmosphere.
(2025). The risk of ischemic stroke in patients with chronic obstructive pulmonary disease and atrial fibrillation. Life.
(2024). Increased risk of psychiatric disorder in patients with hearing loss: A nationwide population-based cohort study. Journal of Translational Medicine.
(2024). Diabetes mellitus and gynecological and inflammation disorders increased the risk of pregnancy loss in a population study. Life.
(2024). The influence of fine particulate matter and cold weather on emergency room interventions for childhood asthma. Life.
(2024). Impact of foodborne disease in Taiwan during the COVID-19 pandemic. Medicina (Lithuania).
(2024). Analyzing COVID-19 and air pollution effects on pediatric asthma emergency room visits in Taiwan. Toxics.
Antiarthritic activities of berberine in a rat model of gouty arthritis. (2025). Scientific Reports.
Unravelling the mechanism by which vildagliptin and linagliptin inhibit pyroptosis in lung injury through the NLRP3 inflammatory pathway in type 1 diabetic rats. (2025). Scientific Reports.
Comparative study of pyridine and pyrimidine derivatives as promising anti-inflammatory agents: Design, synthesis, and LPS-induced RAW 264.7 macrophages. (2025). Drug Development Research.
Expression of growth factors in buffalo ovarian tissue across different follicular developmental stages. (2025). Archives of Gynecology and Obstetrics.
Estrus, preovulatory LH surge and oocyte maturation in Goettingen miniature pigs (Sus scrofa domesticus). (2025). Theriogenology.
Targeting apoptotic pathways in cancer: Design, synthesis, and molecular docking studies of 1,3,5-trisubstituted-1H-pyrazole derivatives with Bcl-2 inhibition and DNA damage potential. (2025). RSC Advances.
Assessment of the gold nanoparticles biosynthesized using Casuarina equisetifolia bark extract against the ethion-induced hepato- and neurotoxicity in rats. (2025). Journal of Genetic Engineering and Biotechnology.
In vitro and in vivo antidiabetic evaluation of new coumarin and chromone derivatives: Design, synthesis, and molecular modeling. (2025). Bioorganic Chemistry.
Potential therapeutic effects of interleukin-1 receptor type 1 antagonist and the ethyl acetate fraction of Murraya exotica leaves against κ-carrageenan-induced vein thrombosis in rats. (2025). Phytomedicine Plus.
The ability of stressor factors of environmental pollution to induce ROS and 8-OHdG mediated apoptosis in fish species of Suez Gulf, Red Sea. (2025). Egyptian Journal of Chemistry.