Dr. Tatsuya Yamasoba is a Professor Emeritus at the University of Tokyo and Director of Tokyo Teishin Hospital, recognized internationally for his contributions to otology, neurotology, laryngology, and clinical neuroscience. He has published over 500 scientific papers in leading journals such as Science, Nature Chemistry, Nature Nanotechnology, Neuron, PNAS, and Neurology. His research focuses on regenerative medicine for sensorineural hearing loss, vestibular dysfunction, and dysphagia management in neurodegenerative diseases. With a citation index of over 24,150, an h-index of 75, and an i10-index of 353, his work has significantly advanced understanding and treatment of auditory and balance disorders. He has developed surgical techniques for severe hearing loss, pioneered galvanic vestibular stimulation therapy for disequilibrium, and improved aspiration prevention surgeries. Dr. Yamasoba has served as Editor-in-Chief of Auris Nasus Larynx and Associate Editor for ORL Journal and npj Aging and Mechanisms of Disease. He collaborates with leading research institutions including the University of Michigan and the University of California, Davis. His professional memberships include the International Federation of ORL Societies and the Asia Oceania Otorhinolaryngology and Head and Neck Society, reflecting his leadership and influence in advancing otolaryngology and auditory neuroscience globally.
Featured Publications
Kujoth, G. C., Hiona, A., Pugh, T. D., Someya, S., Panzer, K., Wohlgemuth, S. E., et al. (2005). Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science, 309(5733), 481–484.
Tokunaga, T., Sakashita, M., Haruna, T., Asaka, D., Takeno, S., Ikeda, H., et al. (2015). Novel scoring system and algorithm for classifying chronic rhinosinusitis: The JESREC study. Allergy, 70(8), 995–1003.
Yamasoba, T., Lin, F. R., Someya, S., Kashio, A., Sakamoto, T., & Kondo, K. (2013). Current concepts in age-related hearing loss: Epidemiology and mechanistic pathways. Hearing Research, 303, 30–38.
Le Prell, C. G., Yamashita, D., Minami, S. B., Yamasoba, T., & Miller, J. M. (2007). Mechanisms of noise-induced hearing loss indicate multiple methods of prevention. Hearing Research, 226(1–2), 22–43.
Umezawa, K., Yoshida, M., Kamiya, M., Yamasoba, T., & Urano, Y. (2017). Rational design of reversible fluorescent probes for live-cell imaging and quantification of fast glutathione dynamics. Nature Chemistry, 9(3), 279–286.
Matsumoto, Y., Nichols, J. W., Toh, K., Nomoto, T., Cabral, H., Miura, Y., et al. (2016). Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery. Nature Nanotechnology, 11(6), 533–538.
Iwasaki, S., & Yamasoba, T. (2014). Dizziness and imbalance in the elderly: Age-related decline in the vestibular system. Aging and Disease, 6(1), 38–47.
Someya, S., Xu, J., Kondo, K., Ding, D., Salvi, R. J., Yamasoba, T., Rabinovitch, P. S., et al. (2009). Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis. Proceedings of the National Academy of Sciences, 106(46), 19432–19437.