Dr. Chahra Chbili is an Assistant Professor of Pharmacology at the Higher School of Health Sciences and Techniques of Sousse (ESSTSS) and a member of the Research Laboratory of Metabolic Biophysics and Applied Pharmacology (LR/12ES02) at the Faculty of Medicine Ibn El Jazzar of Sousse, Tunisia. Her academic journey spans extensive training in biological sciences, genetics, and medical biotechnology, with a Ph.D. earned with highest honors for her work on the pharmacokinetic and pharmacogenetic study of carbamazepine therapy in epileptic and bipolar patients. Dr. Chbili’s research focuses on pharmacogenetics, pharmacokinetics, and the molecular mechanisms underlying drug efficacy and toxicity. She has contributed significantly to studies exploring the genetic determinants of drug metabolism, including investigations into glutathione-S-transferases in tuberculosis patients with drug-induced hepatotoxicity. Skilled in advanced laboratory techniques such as PCR, FISH, ELISA, and HPLC-MS, she has developed expertise in integrating molecular biology with clinical pharmacology. Dr. Chbili has authored 17 scientific documents, accumulated 138 citations across 123 indexed works, and maintains an h-index of 7, reflecting her impactful contributions to pharmacological and biomedical research in Tunisia and beyond.
Featured Publications
Chbili, C., Mrad, S., Graiet, H., Selmi, M., Maatoug, J., Maoua, M., Abdellaoui, L., Mrizek, N., Nouira, M., Ben Fredj, M., et al. (2024). Randomized, placebo-controlled pilot study investigating the effects of Laurus nobilis tea on lipid profiles and oxidative stress biomarkers in healthy North African volunteers. The North African Journal of Food and Nutrition Research, 8(17), 86–98.
Chbili, C., Fathallah, N., Laadhari, C., Ouni, B., Saguem, S., Ben Fredj, M., Abdelghani, A., Ben Saad, H., & Ben Salem, C. (2022). Glutathione-S-transferase genetic polymorphism and risk of hepatotoxicity to antitubercular drugs in a North-African population: A case-control study. Gene, 808, 146019.
Rebai, A., Chbili, C., Ben Amor, S., Hassine, A., Ben Ammou, S., & Saguem, S. (2021). Effects of glutathione S-transferase M1 and T1 deletions on Parkinson’s disease risk among a North African population. Revue Neurologique, 177(1–2), 93–99.
Chbili, C. (2021, August 22). The effect of Origanum majorana tea on motor and non-motor symptoms in patients with idiopathic Parkinson’s disease: A randomized controlled pilot study. Journal article.
Chbili, C., Maoua, M., Selmi, M., Mrad, S., Khairi, H., Limem, K., Mrizek, N., Saguem, S., & Ben Fredj, M. (2020). Evaluation of daily Laurus nobilis tea consumption on lipid profile biomarkers in healthy volunteers. Journal of the American College of Nutrition, 39(6), 518–526.
Rebai, A., Reçber, T., Nemutlu, E., Chbili, C., Kurbanoglu, S., Kir, S., Ben Amor, S., Özkan, S. A., & Saguem, S. (2020). GC-MS based metabolic profiling of Parkinson’s disease with glutathione S-transferase M1 and T1 polymorphism in Tunisian patients. Combinatorial Chemistry and High Throughput Screening, 23(8), 785–794.