Gulcin Gacar | Neurodegenerative Disease | Best Researcher Award

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Assoc. Prof. Dr. Gulcin Gacar | Neurodegenerative Disease | Best Researcher Award

Prof. Dr. Gulcin Gacar | Kocaeli University | Turkey

Associate Professor Dr. Gulcin Gacar of Kocaeli University is a distinguished researcher and educator in the fields of stem cell biology, regenerative medicine, and clinical microbiology. With over 200 scientific publications, including 54 in Web of Science and 37 in Scopus, she has garnered more than 900 citations and achieved an h-index of 17. Her groundbreaking research focuses on mesenchymal stem cells and exosomes, particularly their applications in neurodegenerative diseases like Alzheimer’s. She leads nationally funded projects and serves as a mentor to graduate students, contributing significantly to Turkey’s scientific advancement in cellular and molecular therapy.

Academic Profile

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Early Academic Pursuits

From the outset of her academic journey, Dr. Gülçin Gacar exhibited a strong dedication to medical sciences, particularly clinical microbiology and regenerative medicine. Her foundational studies laid the groundwork for her specialization in stem cell biology and advanced biomedical techniques. As she advanced through the academic ranks, her commitment to translational research became evident, inspiring a deep dive into the dynamic world of mesenchymal stem cells and cellular therapies.

Professional Endeavors

Currently serving as an Associate Professor at Kocaeli University, Dr. Gacar is affiliated with the Center for Stem Cell and Gene Therapies under the Institute of Health Sciences. She plays a critical role in bridging theoretical knowledge with clinical application. Her professional journey is characterized by a robust combination of teaching, research, and leadership, where she supervises graduate-level research and oversees important institutional initiatives in stem cell-based innovation.

Contributions and Research Focus

Dr. Gacar’s research primarily revolves around mesenchymal stem cells, exosomes (extracellular vesicles), and advanced applications of stem cell biology. One of her key projects involves investigating the therapeutic potential of exosomes derived from adipose tissue-origin mesenchymal stem cells on Alzheimer’s disease models using human neuroblastoma SHSY5Y cells. This cutting-edge study, supported by national scientific funding, illustrates her focus on neurological disorders and cellular therapies. With over 200 academic publications, including 54 indexed in Web of Science and 37 in Scopus, her work has become a cornerstone in regenerative medicine and neurocellular research.

Accolades and Recognition

Dr. Gacar’s exceptional scholarship is reflected in her impressive citation record—garnering over 900 citations with an h-index of 16 on Web of Science and 17 on Scopus. These metrics not only underscore the academic relevance of her research but also highlight her influence in the global scientific community. Her contributions have positioned her as a key opinion leader and trusted consultant in TÜBİTAK-funded national projects, further validating her expertise and dedication to scientific excellence.

Impact and Influence

Beyond publications and projects, Dr. Gacar is actively involved in mentoring the next generation of scientists. She has supervised numerous graduate theses, fostering a research culture grounded in innovation, rigor, and ethical science. Her influence extends into policy-making and practical clinical research, making her a vital figure in the implementation of stem cell technologies in both experimental and therapeutic contexts.

Legacy and Future Contributions

Dr. Gacar continues to expand the frontiers of stem cell research and regenerative neuroscience. Her ongoing efforts in developing novel diagnostic and therapeutic modalities through cellular and molecular engineering are poised to transform clinical approaches to degenerative diseases. With each project and publication, she reinforces her commitment to scientific discovery and paves the way for future breakthroughs in biotechnology and personalized medicine.

Neuroscience and Regenerative Innovation

At the intersection of neuroscience and regenerative biology, Dr. Gacar’s work exemplifies the possibilities of interdisciplinary research. Her current focus on exosome-based therapies in neurodegenerative conditions represents a bold step into the future of non-invasive, cell-free therapeutics. As the landscape of neuroscience evolves, her pioneering work will undoubtedly contribute to novel clinical strategies and global scientific advancement.

Publication

Isolation and in vitro characterisation of dental pulp stem cells from natal teeth
E Karaöz, BN Doğan, A Aksoy, G Gacar, S Akyüz, S Ayhan, ZS Genç
2010

Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers
E Karaoz, A Aksoy, S Ayhan, AE Sarıboyacı, F Kaymaz, M Kasap
2009

Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum
K Schallmoser, E Rohde, A Reinisch, C Bartmann, D Thaler, C Drexler, …
2008

High prevalence of OXA-51-type class D β-lactamases among ceftazidime-resistant clinical isolates of Acinetobacter spp.: co-existence with OXA-58 in multiple …
H Vahaboglu, F Budak, M Kasap, G Gacar, S Torol, A Karadenizli, …
2006

Immunoregulatory effects of human dental pulp-derived stem cells on T cells: comparison of transwell co-culture and mixed lymphocyte reaction systems
PC Demircan, AE Sariboyaci, ZS Unal, G Gacar, C Subasi, E Karaoz
2011

Protective effects of resveratrol on aging-induced cognitive impairment in rats
SS Gocmez, N Gacar, T Utkan, G Gacar, PJ Scarpace, N Tumer
2016

The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets
AT Özdemir, RBÖ Özdemir, C Kırmaz, AE Sarıboyacı, ZSÜ Halbutoğlları, …
2016

PER-1 is still widespread in Turkish hospitals among Pseudomonas aeruginosa and Acinetobacter spp.
F Kolayli, G Gacar, A Karadenizli, A Sanic, H Vahaboglu, Study Group
2005

Phenotypic and proteomic characteristics of human dental pulp derived mesenchymal stem cells from a natal, an exfoliated deciduous, and an impacted third molar tooth
G Akpinar, M Kasap, A Aksoy, G Duruksu, G Gacar, E Karaoz
2014

The role of PIN1 on odontogenic and adipogenic differentiation in human dental pulp stem cells
YM Lee, SY Shin, SS Jue, IK Kwon, EH Cho, ES Cho, SH Park, EC Kim
2014

Conclusion 

Considering her scholarly output, impactful research on stem cell-based therapies, leadership in national research initiatives, and dedication to mentoring, Dr. Gulcin Gacar is highly deserving of the Best Researcher Award. Her innovative work in exosome-based treatment strategies for neurodegenerative diseases positions her as a leader in translational medical science. With continued emphasis on global engagement and high-impact dissemination, her research will not only advance scientific frontiers but also contribute meaningfully to patient care and public health. Thus, she stands as an exemplary model of academic excellence, innovation, and social relevance in biomedical sciences.

Sukesh Sinha | Neuropharmacology | Lifetime achievement Award

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Prof. Dr. Sukesh Sinha | Neuropharmacology | Lifetime achievement Award

Prof. Dr. Sukesh Sinha,  National Institute of Nutrition-ICMR, India.

Dr. Sukesh Narayan Sinha, a seasoned toxicologist and research leader, has dedicated his career to advancing the fields of food safety, drug toxicology, pesticide toxicology, and pharmacology. Starting with a strong academic foundation in chemistry from Bihar University, he honed his expertise further through international training at the University of Helsinki and the CDC in the USA. Rising through the ranks of India’s premier health research institutions under the ICMR, Dr. Sinha’s career spans critical research roles that have directly impacted national health and safety policies. His global collaborations and leadership roles reflect a career built on scientific rigor, public service, and continuous learning.

Profile

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🎓 Early Academic Pursuits

Born on January 3rd, 1965, Dr. Sukesh Narayan Sinha’s academic journey began with a profound interest in the field of chemistry. He earned his B.Sc. Honours in Chemistry in 1989, followed by an M.Sc. in Chemistry in 1993, and later a Ph.D. in Chemistry in 1999—all from Bihar University, Muzaffarpur. His pursuit of advanced scientific knowledge extended internationally, where he underwent specialized analytical skill development in toxicology at the University of Helsinki, Finland. These foundational years cemented his passion for chemical and toxicological research, shaping the path for a distinguished career in public health and environmental safety.

🧪 Professional Endeavors in Toxicology

Dr. Sinha’s career has been marked by continuous progression through India’s foremost medical and research institutions under the Indian Council of Medical Research (ICMR). Beginning as a Research Fellow at the National Institute of Malaria Research, he moved into industry as a Research Scientist at Alkame Laboratory. His return to the ICMR system in 2001 marked the beginning of a steady ascent through scientific ranks—from Scientist-B to his current post as Senior Grade Deputy Director (Scientist-F) at the ICMR-National Institute of Nutrition (NIN), Hyderabad. He also held key roles at the ICMR-National Institute of Occupational Health, contributing immensely to occupational and environmental health research.

🧬 Contributions and Research Focus

Specializing in Food Toxicology, Drug Research & Toxicology, Pesticide Toxicology, and Pharmacology, Dr. Sinha has focused on identifying and mitigating chemical risks in food and the environment. His work has had a direct impact on public health safety standards in India. Through advanced analytical techniques and interdisciplinary collaboration, he has played a central role in guiding policy and regulatory frameworks concerning food safety. His expertise has not only contributed to toxicological research but has also enhanced national capacities in monitoring hazardous substances affecting human health.

🌍 Global Collaborations and Scientific Exposure

Dr. Sinha’s vision and research have reached global platforms. Notably, he served as a Visiting Scientist at the University of Cincinnati, USA, where he collaborated with experts in Environmental Health. He also completed two intensive courses on health and safety under the Centers for Disease Control and Prevention (CDC) in Atlanta, USA. These international exposures have enriched his scientific perspective, enabling him to incorporate global best practices into India’s health safety frameworks and toxicology research protocols.

🏅 Accolades and Recognition

Throughout his career, Dr. Sinha has earned recognition for his commitment and excellence in scientific research. While specific awards are not listed, his steady promotion within the ICMR ranks—from Scientist-B to Scientist-F—reflects institutional trust in his capabilities and leadership. His selection as a visiting scientist abroad and participation in elite training programs also underscore his status as a respected voice in toxicology and public health research.

📢 Impact and Influence on Public Health

Through his extensive research and governmental role, Dr. Sinha has contributed to national strategies on food safety and toxic substance regulation. His input influences decisions affecting millions of citizens, especially in areas related to food contaminants, drug residues, and environmental pollutants. He continues to serve as a bridge between laboratory research and real-world applications that safeguard public health in India.

🔬 Legacy and Future Contributions

Dr. Sinha’s legacy lies in his unwavering commitment to science and service. With decades of experience and an expanding portfolio of national and international collaborations, he is poised to continue influencing future research, shaping young scientific minds, and contributing to India’s health security. His role at ICMR-NIN ensures that his insights and leadership will guide public health policies and toxicology advancements for years to come.

Publication

  • Quantification of organophosphate insecticides and herbicides in vegetable samples using the “Quick Easy Cheap Effective Rugged and Safe” (QuEChERS) method and a high …
    SN Sinha, K Vasudev, MVV Rao – 2012

 

  • Distribution of pesticides in different commonly used vegetables from Hyderabad, India
    SN Sinha, MVV Rao, K Vasudev – 2012

 

  • Air pollution from solid fuels.
    SN Sinha, PK Nag – 2011

 

  • Environmental monitoring of benzene and toluene produced in indoor air due to combustion of solid biomass fuels
    SN Sinha, PK Kulkarni, SH Shah, NM Desai, GM Patel, MM Mansuri, … – 2006

 

  • Repeated episodes of endosulfan poisoning
    A Dewan, VK Bhatnagar, ML Mathur, T Chakma, R Kashyap, HG Sadhu, … – 2004

 

  • Effect of dissociation energy on ion formation and sensitivity of an analytical method for determination of chlorpyrifos in human blood, using gas chromatography–mass …
    SN Sinha, R Pal, A Dewan, MM Mansuri, HN Saiyed – 2006

 

  • A novel method for pesticide analysis in refined sugar samples using a gas chromatography–mass spectrometer (GC–MS/MS) and simple solvent extraction method
    SN Sinha, VK Bhatnagar, P Doctor, GS Toteja, NP Agnihotri, RL Kalra – 2011

 

  • A liquid chromatography mass spectrometry-based method to measure organophosphorous insecticide, herbicide and non-organophosphorous pesticide in grape and apple samples
    SN Sinha, MVV Rao, K Vasudev, M Odetokun – 2012

 

  • Quantification of organophosphate insecticides in drinking water in urban areas using lyophilization and high-performance liquid chromatography–electrospray ionization-mass …
    SN Sinha, K Vasudev, MVV Rao, M Odetokun – 2011

 

  • Inhibition of protein glycation by procyanidin‐B2 enriched fraction of cinnamon: delay of diabetic cataract in rats
    P Muthenna, G Raghu, C Akileshwari, SN Sinha, P Suryanarayana, … – 2013

 

🏁 Conclusion

Dr. Sukesh Narayan Sinha stands as a respected figure in India’s scientific community, with an enduring impact on toxicology research and public health safety. His career reflects a seamless integration of deep scientific knowledge, practical application, and international collaboration. As he continues his service at ICMR-NIN, his contributions promise to leave a lasting legacy in strengthening food safety standards, environmental health, and public policy for future generations. Dr. Sinha’s journey inspires commitment to research excellence and exemplifies the profound role of science in safeguarding society.