Prof. Lin Jizhen | Cancer immunotherapy | Best Researcher Award

Prof.  Lin Jizhen, Union Hospital, Fujian Medical University, China.

Dr. Jizhen Lin is a distinguished physician-scientist whose career has been defined by an unwavering dedication to the field of auditory molecular biology. With his foundational medical education from Fujian Medical University and advanced research training in biochemistry and molecular biology at the University of Minnesota, he has seamlessly blended clinical acumen with scientific innovation. His professional roles have evolved from intern and research fellow to Associate Professor and Laboratory Director, reflecting a career rich in mentorship, discovery, and leadership. His research has focused extensively on otitis media and the molecular mechanisms of hearing, contributing valuable insights into the pathophysiology and potential treatments of auditory disorders.

Profile

Scopus

 

📚 Early Academic Pursuits

Dr. Jizhen Lin’s academic journey began with a strong foundation in medicine at Fujian Medical University, Fuzhou, China, where he earned his M.D. in 1982 and an M.S. in Otolaryngology in 1987. His thirst for advanced knowledge and scientific discovery later brought him to the University of Minnesota, Minneapolis, where he immersed himself in the fields of biochemistry and molecular biology, further enriching his expertise and setting the stage for a robust research career in auditory sciences.

🧪 Professional Endeavors

Dr. Lin’s professional path has been marked by consistent dedication and a progressive climb through academic and research positions. His early clinical exposure as an intern at Union Hospital in Fujian laid the groundwork for his subsequent transition into research. Between 1992 and 1995, he served as an International Research Fellow at the Otitis Media Research Center (OMRC), University of Minnesota. He continued to make strides as a Research Scientist and Co-director of the Otopathology-Molecular Biology Laboratory, contributing significantly to auditory molecular biology. His leadership abilities culminated in his appointment as Director of the Auditory Molecular Biology Laboratory, and he has been serving as an Associate Professor in the Department of Otolaryngology at the University of Minnesota Medical School since 2008.

🔬 Contributions and Research Focus

Throughout his career, Dr. Lin has concentrated on unraveling the complexities of auditory molecular biology with a primary focus on otitis media, a prevalent childhood disease. His contributions have been instrumental in bridging clinical otolaryngology with molecular science, employing biochemical tools to investigate the pathogenesis of auditory disorders. His laboratory has played a critical role in advancing understanding of the genetic and cellular mechanisms that underpin hearing loss and middle ear infections, particularly through innovative translational approaches.

🏅 Accolades and Recognition

Dr. Lin’s relentless pursuit of scientific excellence and impactful research has earned him widespread recognition in the field of otolaryngology. His tenure as a Graduate Faculty advisor reflects not only his dedication to mentorship but also the high regard his peers and the academic community have for his expertise. While he may not be adorned with numerous public awards, the esteem in which he is held by colleagues and students alike underscores the quiet yet profound impact of his scholarly work.

🌍 Impact and Influence

The influence of Dr. Lin’s research extends beyond the laboratory, as his findings have contributed meaningfully to clinical practices and therapeutic approaches in otolaryngology. By identifying key molecular targets and pathways involved in auditory disorders, his work continues to shape the development of novel diagnostics and treatments. Furthermore, his role in international research collaborations underscores his commitment to knowledge exchange and global scientific advancement.

🧠 Legacy and Future Contributions

Dr. Lin’s legacy is firmly rooted in the integration of molecular science with clinical otolaryngology, a field he has helped shape through decades of dedicated research and academic mentorship. As a mentor to future scientists and a contributor to critical advancements in auditory health, he remains a cornerstone in the bridge between basic science and patient care. Looking forward, his ongoing work in auditory molecular biology is poised to further uncover the mechanisms of hearing and hearing loss, promising new frontiers in medical intervention and auditory health.

🧬 Lifelong Commitment to Hearing Science

Dr. Lin’s career embodies a lifelong commitment to auditory science, from the clinic to the lab. His seamless blend of clinical knowledge, molecular expertise, and research leadership has fostered a rich legacy in otolaryngology. With ongoing contributions to scientific understanding and future discoveries on the horizon, Dr. Lin continues to inspire a generation of researchers and clinicians dedicated to improving hearing health worldwide.

Publication

1. Title: Cell-free transcription amplification-based split-type electrochemical sensor using enzyme-linked magnetic microbeads for minimal residual leukemia detection
   Authors: Luying Yu, Jinyuan Chen, Huanjiao Weng, … Xinhua Lin, Guangxian Zhong
   Year: 2025

 

1. Title: Antibody screening-assisted multichannel nanoplasmonic sensing chip based on SERS for viral screening and variants identification
   Authors: Yi Liu, Huanjiao Weng, Zhiwei Chen, … Shangyuan Feng, Duo Lin
   Year: 2025

 

1. Title: tRNA methyltransferase DNMT2 promotes hepatocellular carcinoma progression and enhances Bortezomib resistance through inhibiting TNFSF10
   Authors: Junzhong Lai, Linqin Chen, Qiumei Li, … Jizhen Lin, Qi Chen
   Year: 2025

 

1. Title: Carrimycin ameliorates lipopolysaccharide and cecal ligation and puncture-induced sepsis in mice
   Authors: Junzhong Lai, Jiadi Liang, Kunsen Chen, … Qi Chen, Jizhen Lin
   Year: 2024

 

1. Title: B7H3 targeting gold nanocage pH-sensitive conjugates for precise and synergistic chemo-photothermal therapy against NSCLC
   Authors: Bing Chen, Kaifan Zheng, Shubin Fang, … Jizhen Lin, Xinhua Lin
   Year: 2023

 

1. Title: A drug-delivery depot for epigenetic modulation and enhanced cancer immunotherapy
   Authors: Junzhong Lai, Jiadi Liang, Yong Zhang, … Jizhen Lin, Qi Chen
   Year: 2023

 

1. Title: Ultrasensitive detection of SARS-CoV-2 antigen using surface-enhanced Raman spectroscopy-based lateral flow immunosensor
   Authors: Shuxia Lai, Yi Liu, Shubin Fang, … Jizhen Lin, Shangyuan Feng
   Year: 2023

 

1. Title: Retraction Note to: Linc00210 drives Wnt/β-catenin signaling activation and liver tumor progression through CTNNBIP1-dependent manner
   Authors: Xiaomin Fu, Xiaoyan Zhu, Fujun Qin, … Qinxian Zhang, Quanli Gao
   Year: Not specified

 

1. Title: SFPQ Promotes Lung Cancer Malignancy via Regulation of CD44 v6 Expression
   Authors: Libang Yang, Jiangbo Yang, Blake A. Jacobson, … Craig A. Henke, Jizhen Lin
   Year: 2022

 

✅ Conclusion

Dr. Lin’s lifelong commitment to understanding the science of hearing has positioned him as a pioneering figure in otolaryngology. Through decades of research, academic guidance, and clinical collaboration, he has built a legacy rooted in translational science and patient-centered innovation. His work continues to influence both basic research and clinical practice, promising a future where auditory health is better understood and more effectively managed. As a scientist, mentor, and innovator, Dr. Lin stands as an enduring contributor to the advancement of hearing science.