Eleni Tsakiri | Foundations of Neuroscience | Best Researcher Award

Published on by Neuroscientists

Dr. Eleni Tsakiri | Foundations of Neuroscience | Best Researcher Award

Dr. Eleni Tsakiri |  National and Kapodistrian University of Athens Medical School | Greece

Dr. Eleni Tsakiri is a distinguished Molecular Biologist whose research centers on the molecular mechanisms of aging, proteostasis, and neurodegeneration. She earned her Ph.D. in Biology from the National and Kapodistrian University of Athens (NKUA) with a thesis on proteome homeostasis and its alterations during aging, following her M.Sc. in Cell Biology and Biophysics and a B.Sc. in Molecular Biology and Genetics. Dr. Tsakiri has held multiple postdoctoral positions at leading Greek institutions, including the Medical School of NKUA and the Biomedical Research Center “Alexander Fleming,” where she contributed to projects on proteasome regulation, Tau aggregation, and ribosome-mediated cell competition. Currently, she serves as a Postdoctoral Researcher at the Laboratory of Physiology, NKUA, focusing on neurodegeneration and aging under an ERC-funded project. Her research is supported by competitive grants such as the Hellenic Foundation for Research and Innovation (HFRI). She has supervised undergraduate, master’s, and doctoral students and actively collaborates with prominent researchers in Greece and abroad. Dr. Tsakiri’s contributions are reflected in her 24 published documents, 730 citations, and an h-index of 15, highlighting her impact in molecular biology and aging research.

Profiles: Scopus | Google Scholar | Research Gate | LInked In

Featured Publications

  • Tsakiri, E. N., Sykiotis, G. P., Papassideri, I. S., Terpos, E., Dimopoulos, M. A., & others. (2013). Proteasome dysfunction in Drosophila signals to an Nrf2‐dependent regulatory circuit aiming to restore proteostasis and prevent premature aging. Aging Cell, 12(5), 802–813.

  • Tsakiri, E. N., Sykiotis, G. P., Papassideri, I. S., Gorgoulis, V. G., Bohmann, D., & others. (2013). Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress. The FASEB Journal, 27(6), 2407–2419.

  • Tsakiri, E. N., & Trougakos, I. P. (2015). The amazing ubiquitin-proteasome system: Structural components and implication in aging. International Review of Cell and Molecular Biology, 314, 171–237.

  • Tsakiri, E. N., Iliaki, K. K., Höhn, A., Grimm, S., Papassideri, I. S., & Grune, T. (2013). Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster. Free Radical Biology and Medicine, 65, 1155–1163.

  • Tsakiri, E. N., Gumeni, S., Iliaki, K. K., Benaki, D., Vougas, K., Sykiotis, G. P., et al. (2019). Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation. Aging Cell, 18(1), e12845.