Soheila Hosseinzadeh | Cognitive Neuroscience | Best Researcher Award

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Assoc. Prof. Dr. Soheila Hosseinzadeh | Cognitive Neuroscience | Best Researcher Award

Assist. Prof. Dr. Soheila Hosseinzadeh, Tehran University of Medical Sciences, Iran.

Dr. Soheila Hosseinzadeh is a distinguished Assistant Professor of Neuroscience at the Tehran University of Medical Sciences, with a rich academic background that spans nursing, physiology, and neuroscience. Over the years, she has made substantial contributions to neuroscience education and research, particularly in the fields of cognitive neurophysiology and addiction studies. Her expertise includes a wide range of advanced techniques such as event-related potential analysis, EEG-based neurofeedback, behavioral studies, and molecular tools like RT-PCR and ELISA. She has played a pivotal role in training students and developing neuroscience programs at multiple academic institutions, demonstrating a balanced commitment to both teaching and scientific innovation.

Academic Profile

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Early Academic Pursuits

Dr. Soheila Hosseinzadeh’s academic foundation is deeply rooted in an interdisciplinary understanding of human physiology and neurological sciences. Her early career began with a Bachelor of Science in Nursing in 2000, which was soon followed by a Master’s degree in Physiology in 2003. Demonstrating a keen interest in the mechanisms underlying brain function and behavior, she further advanced her expertise by earning a Ph.D. in Neuroscience in 2013. These academic milestones laid a solid groundwork for her future in teaching and cutting-edge neurophysiological research.

Professional Endeavors in Neuroscience

After completing her Ph.D., Dr. Hosseinzadeh embarked on an academic and research-oriented career that has spanned over a decade. From 2014 to April 2022, she served as a neurophysiology course instructor at Babol University of Medical Sciences, nurturing future scientists with her in-depth understanding of brain physiology. Since April 2022, she has continued her academic contributions at the Tehran University of Medical Sciences, where she teaches courses in Neuroscience and Addiction Studies. Her dual role as educator and researcher places her at the forefront of neuroscience education in Iran.

Contributions and Research Focus

Dr. Hosseinzadeh’s research is focused on the interface of cognitive neuroscience and addiction studies. Her technical proficiency includes advanced neurophysiological techniques such as event-related potential (ERP) recording and analysis, quantitative EEG (QEEG)-based neurofeedback, and behavioral assessments in animal models. She is also experienced in molecular biology tools including real-time RT-PCR and ELISA, alongside rodent stereotaxic surgeries and flow cytometry. Her work often explores neural mechanisms underlying cognitive functions, brain plasticity, and responses to addictive substances—bridging lab findings with clinical relevance.

Accolades and Recognition

Throughout her academic journey, Dr. Hosseinzadeh has earned recognition for her expertise in neurophysiological and behavioral science. Her dual roles at prestigious institutions such as Tehran University of Medical Sciences reflect her trusted authority in the field. While her accolades are more rooted in impact and mentorship than in public awards, her consistent engagement in neuroscience education and translational research is a clear indicator of peer acknowledgment and professional respect.

Impact and Influence

Dr. Hosseinzadeh’s influence extends beyond academic teaching. By integrating theoretical neuroscience with hands-on technical applications like neurofeedback and EEG-based cognitive training, she fosters a research culture that promotes both clinical innovation and scientific discovery. Her guidance has shaped students and young researchers in multiple universities, many of whom continue to advance the fields of neurophysiology and cognitive rehabilitation across the country.

Legacy in Neurotechnology and Cognitive Health

Her pioneering efforts in cognitive task design and ERP analysis have significantly contributed to Iran’s growing reputation in brain research. As one of the few experts integrating neurofeedback with behavioral science and electrophysiology, Dr. Hosseinzadeh has helped establish a platform for neurotechnological interventions in addiction and mental health studies. Her legacy lies in creating an interdisciplinary approach that merges neuroscientific inquiry with practical healthcare applications.

Future Contributions and Vision

Looking ahead, Dr. Soheila Hosseinzadeh is poised to make even greater strides in neuroscience, particularly in the domains of addiction neurobiology, cognitive rehabilitation, and neurofeedback therapy. With continuous advancements in brain-monitoring tools and behavioral modeling, she aims to lead research projects that offer deeper insights into brain-behavior relationships and provide innovative treatments for neuropsychiatric disorders. Her vision includes developing collaborative research networks that connect Iranian neuroscience to global scientific conversations.

Publication

Piperine restores streptozotocin-induced cognitive impairments: Insights into oxidative balance in cerebrospinal fluid and hippocampus
M Khalili-Fomeshi, MG Azizi, MR Esmaeili, M Gol, S Kazemi, …
2018

Plasma microparticles in Alzheimer’s disease: The role of vascular dysfunction
S Hosseinzadeh, M Noroozian, E Mortaz, K Mousavizadeh
2018

Elevated CSF and plasma microparticles in a rat model of streptozotocin-induced cognitive impairment
S Hosseinzadeh, M Zahmatkesh, MR Zarrindast, GR Hassanzadeh, …
2013

Effect of methamphetamine exposure on the plasma levels of endothelial-derived microparticles
A Nazari, M Zahmatkesh, E Mortaz, S Hosseinzadeh
2018

Hippocampal DHCR24 down regulation in a rat model of streptozotocin-induced cognitive decline
S Hosseinzadeh, M Zahmatkesh, M Heidari, GR Hassanzadeh, …
2015

Increment of CSF fractalkine-positive microvesicles preceded the spatial memory impairment in amyloid beta neurotoxicity
L Karimi-Zandi, M Zahmatkesh, G Hassanzadeh, S Hosseinzadeh
2022

Arbutin intervention ameliorates memory impairment in a rat model of lysolecethin induced demyelination: Neuroprotective and anti-inflammatory effects
S Ashrafpour, MJ Nasr-Taherabadi, A Sabouri-Rad, S Hosseinzadeh, …
2024

Conclusion

Dr. Hosseinzadeh’s career reflects an exemplary blend of academic excellence, technical expertise, and visionary research in neuroscience. Her efforts have significantly advanced the understanding of brain function, particularly in the context of addiction and cognitive health. As a leader in her field, she continues to inspire the next generation of neuroscientists while actively contributing to translational research that bridges laboratory findings with clinical solutions. With her ongoing work and future vision, Dr. Hosseinzadeh stands out as a key figure in shaping the future of neuroscience in Iran and beyond.

Jeffrey Holt | Hearing and Sensory Transduction | Lifetime achievement Award

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Prof. Jeffrey Holt | Hearing and Sensory Transduction | Lifetime achievement Award

Prof. Jeffrey Holt,  Harvard Medical School / Boston Children’s Hospital, United States.

Dr. Jeffrey R. Holt is a distinguished scientist whose groundbreaking contributions to auditory neuroscience and inner ear physiology have significantly advanced the field of otolaryngology. Currently serving as a Professor of Otolaryngology and Neurology at Boston Children’s Hospital and Harvard Medical School, Dr. Holt’s career is marked by an unwavering commitment to understanding the molecular and physiological mechanisms underlying hearing and balance disorders.

Profile

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Early Academic Pursuits 🎓

Born in Buffalo, NY, Dr. Holt’s passion for science was evident early in his academic journey. He earned his Bachelor of Science degree in Biology from Wofford College in 1986, laying a strong foundation in the life sciences. His quest for knowledge led him to the University of Rochester, where he pursued a Master’s degree in Physiology in 1992, followed by a Ph.D. in Physiology in 1995. His doctoral research provided deep insights into the intricate workings of sensory physiology, setting the stage for his future research endeavors in auditory neuroscience.

Professional Endeavors and Leadership 👩‍💼

Following his Ph.D., Dr. Holt embarked on postdoctoral training at Harvard Medical School, Massachusetts General Hospital, and the Howard Hughes Medical Institute. His extensive training in neurobiology enabled him to transition into academic roles, beginning as an Instructor in Neurobiology at Harvard Medical School and Massachusetts General Hospital from 1999 to 2001. He later joined the University of Virginia as an Assistant Professor of Neuroscience, where he progressed to Associate Professor before returning to Harvard in 2011. Since 2016, he has held the esteemed position of Professor of Otolaryngology at Boston Children’s Hospital and Harvard Medical School, as well as a faculty affiliation with the Harvard-MIT Health Sciences and Technology (HST) program.

Contributions and Research Focus 🌍

Dr. Holt’s pioneering research has been instrumental in decoding the molecular basis of hearing and balance disorders. His work focuses on sensory hair cells of the inner ear, aiming to uncover the genetic and physiological mechanisms that contribute to hearing loss. His studies have explored ion channel function, hair cell mechanotransduction, and gene therapy approaches for hereditary deafness. His innovative research has opened new avenues for therapeutic interventions, including the development of gene therapies targeting Usher syndrome and other genetic hearing disorders.

Accolades and Recognition 🏆

Throughout his career, Dr. Holt has been widely recognized for his contributions to auditory science. He has played key leadership roles in prestigious scientific organizations, serving as Chair of the Usher Syndrome Society Scientific Advisory Committee and Co-Chair of major international conferences such as the Keystone Conference on Sensory Systems and the New York Academy of Sciences Meeting. His service on various NIH and NIDCD advisory committees reflects his influence in shaping national research priorities in hearing and balance disorders.

Impact and Influence on Scientific Community 🌐

Dr. Holt’s impact extends beyond research, as he has been a dedicated mentor and educator throughout his career. He has guided numerous graduate students and postdoctoral fellows, serving on thesis and qualifying exam committees at Harvard Medical School. As a course director and research mentor, he has played a crucial role in training the next generation of auditory neuroscientists. His leadership in academic and scientific communities has helped bridge the gap between fundamental research and clinical applications in hearing restoration.

Legacy and Future Contributions 💪

With a legacy rooted in groundbreaking discoveries and scientific leadership, Dr. Holt continues to push the boundaries of auditory neuroscience. His ongoing research in gene therapy for hereditary deafness holds the promise of transforming lives through novel treatments for hearing loss. As a visionary in the field, his work is set to inspire future advancements in otolaryngology, offering hope to millions affected by hearing and balance disorders worldwide. His dedication to research, education, and clinical impact ensures that his contributions will leave a lasting imprint on auditory science for generations to come.

 

Publication

  • TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells
    Authors: DP Corey, J García-Añoveros, JR Holt, KY Kwan, SY Lin, MA Vollrath, …
    Year: 2004

 

  • Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents
    Authors: X Gao, Y Tao, V Lamas, M Huang, WH Yeh, B Pan, YJ Hu, JH Hu, …
    Year: 2018

 

  • Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes
    Authors: Y Kawashima, GSG Géléoc, K Kurima, V Labay, A Lelli, Y Asai, …
    Year: 2011

 

  • TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear
    Authors: B Pan, GS Géléoc, Y Asai, GC Horwitz, K Kurima, K Ishikawa, …
    Year: 2013

 

  • Continuous evolution of base editors with expanded target compatibility and improved activity
    Authors: BW Thuronyi, LW Koblan, JM Levy, WH Yeh, C Zheng, GA Newby, …
    Year: 2019

 

  • Differential distribution of stem cells in the auditory and vestibular organs of the inner ear
    Authors: K Oshima, CM Grimm, CE Corrales, P Senn, R Martinez Monedero, …
    Year: 2007

 

  • A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells
    Authors: JR Holt, SKH Gillespie, DW Provance, K Shah, KM Shokat, DP Corey, …
    Year: 2002

 

  • A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear
    Authors: LD Landegger, B Pan, C Askew, SJ Wassmer, SD Gluck, A Galvin, …
    Year: 2017

 

  • Calcium imaging of single stereocilia in hair cells: localization of transduction channels at both ends of tip links
    Authors: W Denk, JR Holt, GMG Shepherd, DP Corey
    Year: 1995

 

  • TMC1 forms the pore of mechanosensory transduction channels in vertebrate inner ear hair cells
    Authors: B Pan, N Akyuz, XP Liu, Y Asai, C Nist-Lund, K Kurima, BH Derfler, …
    Year: 2018

 

Conclusion 🎯

Dr. Holt’s contributions to auditory neuroscience have revolutionized the field, bridging fundamental research with clinical applications. His groundbreaking work in gene therapy holds immense potential for treating hereditary hearing disorders, making a profound impact on global healthcare. As a researcher, educator, and leader, his legacy will continue to inspire innovation in otolaryngology and improve the lives of individuals affected by hearing and balance impairments for generations to come.