Assoc. Prof. Dr. Gulcin Gacar | Neurodegenerative Disease | Best Researcher Award
Prof. Dr. Gulcin Gacar | Kocaeli University | Turkey
Associate Professor Dr. Gulcin Gacar of Kocaeli University is a distinguished researcher and educator in the fields of stem cell biology, regenerative medicine, and clinical microbiology. With over 200 scientific publications, including 54 in Web of Science and 37 in Scopus, she has garnered more than 900 citations and achieved an h-index of 17. Her groundbreaking research focuses on mesenchymal stem cells and exosomes, particularly their applications in neurodegenerative diseases like Alzheimer’s. She leads nationally funded projects and serves as a mentor to graduate students, contributing significantly to Turkey’s scientific advancement in cellular and molecular therapy.
Academic Profile
Early Academic Pursuits
From the outset of her academic journey, Dr. Gülçin Gacar exhibited a strong dedication to medical sciences, particularly clinical microbiology and regenerative medicine. Her foundational studies laid the groundwork for her specialization in stem cell biology and advanced biomedical techniques. As she advanced through the academic ranks, her commitment to translational research became evident, inspiring a deep dive into the dynamic world of mesenchymal stem cells and cellular therapies.
Professional Endeavors
Currently serving as an Associate Professor at Kocaeli University, Dr. Gacar is affiliated with the Center for Stem Cell and Gene Therapies under the Institute of Health Sciences. She plays a critical role in bridging theoretical knowledge with clinical application. Her professional journey is characterized by a robust combination of teaching, research, and leadership, where she supervises graduate-level research and oversees important institutional initiatives in stem cell-based innovation.
Contributions and Research Focus
Dr. Gacar’s research primarily revolves around mesenchymal stem cells, exosomes (extracellular vesicles), and advanced applications of stem cell biology. One of her key projects involves investigating the therapeutic potential of exosomes derived from adipose tissue-origin mesenchymal stem cells on Alzheimer’s disease models using human neuroblastoma SHSY5Y cells. This cutting-edge study, supported by national scientific funding, illustrates her focus on neurological disorders and cellular therapies. With over 200 academic publications, including 54 indexed in Web of Science and 37 in Scopus, her work has become a cornerstone in regenerative medicine and neurocellular research.
Accolades and Recognition
Dr. Gacar’s exceptional scholarship is reflected in her impressive citation record—garnering over 900 citations with an h-index of 16 on Web of Science and 17 on Scopus. These metrics not only underscore the academic relevance of her research but also highlight her influence in the global scientific community. Her contributions have positioned her as a key opinion leader and trusted consultant in TÜBİTAK-funded national projects, further validating her expertise and dedication to scientific excellence.
Impact and Influence
Beyond publications and projects, Dr. Gacar is actively involved in mentoring the next generation of scientists. She has supervised numerous graduate theses, fostering a research culture grounded in innovation, rigor, and ethical science. Her influence extends into policy-making and practical clinical research, making her a vital figure in the implementation of stem cell technologies in both experimental and therapeutic contexts.
Legacy and Future Contributions
Dr. Gacar continues to expand the frontiers of stem cell research and regenerative neuroscience. Her ongoing efforts in developing novel diagnostic and therapeutic modalities through cellular and molecular engineering are poised to transform clinical approaches to degenerative diseases. With each project and publication, she reinforces her commitment to scientific discovery and paves the way for future breakthroughs in biotechnology and personalized medicine.
Neuroscience and Regenerative Innovation
At the intersection of neuroscience and regenerative biology, Dr. Gacar’s work exemplifies the possibilities of interdisciplinary research. Her current focus on exosome-based therapies in neurodegenerative conditions represents a bold step into the future of non-invasive, cell-free therapeutics. As the landscape of neuroscience evolves, her pioneering work will undoubtedly contribute to novel clinical strategies and global scientific advancement.
Publication
Isolation and in vitro characterisation of dental pulp stem cells from natal teeth
E Karaöz, BN Doğan, A Aksoy, G Gacar, S Akyüz, S Ayhan, ZS Genç
2010
Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers
E Karaoz, A Aksoy, S Ayhan, AE Sarıboyacı, F Kaymaz, M Kasap
2009
Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum
K Schallmoser, E Rohde, A Reinisch, C Bartmann, D Thaler, C Drexler, …
2008
High prevalence of OXA-51-type class D β-lactamases among ceftazidime-resistant clinical isolates of Acinetobacter spp.: co-existence with OXA-58 in multiple …
H Vahaboglu, F Budak, M Kasap, G Gacar, S Torol, A Karadenizli, …
2006
Immunoregulatory effects of human dental pulp-derived stem cells on T cells: comparison of transwell co-culture and mixed lymphocyte reaction systems
PC Demircan, AE Sariboyaci, ZS Unal, G Gacar, C Subasi, E Karaoz
2011
Protective effects of resveratrol on aging-induced cognitive impairment in rats
SS Gocmez, N Gacar, T Utkan, G Gacar, PJ Scarpace, N Tumer
2016
The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets
AT Özdemir, RBÖ Özdemir, C Kırmaz, AE Sarıboyacı, ZSÜ Halbutoğlları, …
2016
PER-1 is still widespread in Turkish hospitals among Pseudomonas aeruginosa and Acinetobacter spp.
F Kolayli, G Gacar, A Karadenizli, A Sanic, H Vahaboglu, Study Group
2005
Phenotypic and proteomic characteristics of human dental pulp derived mesenchymal stem cells from a natal, an exfoliated deciduous, and an impacted third molar tooth
G Akpinar, M Kasap, A Aksoy, G Duruksu, G Gacar, E Karaoz
2014
The role of PIN1 on odontogenic and adipogenic differentiation in human dental pulp stem cells
YM Lee, SY Shin, SS Jue, IK Kwon, EH Cho, ES Cho, SH Park, EC Kim
2014
Conclusion
Considering her scholarly output, impactful research on stem cell-based therapies, leadership in national research initiatives, and dedication to mentoring, Dr. Gulcin Gacar is highly deserving of the Best Researcher Award. Her innovative work in exosome-based treatment strategies for neurodegenerative diseases positions her as a leader in translational medical science. With continued emphasis on global engagement and high-impact dissemination, her research will not only advance scientific frontiers but also contribute meaningfully to patient care and public health. Thus, she stands as an exemplary model of academic excellence, innovation, and social relevance in biomedical sciences.