Dr. Watit Sontising | Icahn school of medicine at mount sinai | United States
Dr. Watit Sontising is a distinguished chemist whose career seamlessly integrates academic scholarship, industrial innovation, and biomedical research. With a foundation built through advanced studies in chemistry, his expertise spans computational modeling, analytical method development, and environmental compliance. His academic contributions include years of teaching and mentoring in general chemistry, fostering critical thinking and practical skills among diverse student groups. Professionally, he has advanced laboratory efficiency in environmental and industrial chemistry while later transitioning into biotechnology and biomedical research. His current postdoctoral work at the Icahn School of Medicine at Mount Sinai exemplifies his interdisciplinary impact, where he pioneers mass spectrometry imaging and metabolomic profiling to explore neurological disorders. Through a robust portfolio of publications and methodological innovations, he has significantly contributed to the fields of crystallography, material science, and spatial metabolomics.
Profile
Early Academic Pursuits
Dr. Watit Sontising began his academic journey in chemistry with a strong foundation developed during his undergraduate studies in Thailand. His early exposure to chemical sciences sparked a curiosity for understanding molecular interactions and their implications in both natural and applied systems. Pursuing graduate studies in the United States, he advanced his expertise through master’s and doctoral programs in chemistry at the University of California, Riverside. During this time, he immersed himself in research on molecular interactions, computational chemistry, and crystallography, laying the groundwork for a career that bridges theory, experimentation, and application.
Professional Endeavors
His professional trajectory reflects a balance between academia and industry, allowing him to refine skills across diverse environments. At California State University, Fullerton, and later at the University of California, Riverside, he served as a teaching assistant in general chemistry, where he engaged directly with undergraduate students through lectures, laboratory instruction, and mentorship. Following his doctoral studies, he contributed to environmental chemistry as a laboratory manager, spearheading compliance-driven analytical methods, and later transitioned into the biotechnology sector as a research scientist, applying analytical and modeling techniques to sustainable material development. His current role as a postdoctoral fellow in neurology at the Icahn School of Medicine at Mount Sinai demonstrates his interdisciplinary adaptability, integrating chemistry with neuroscience to advance biomedical research.
Contributions and Research Focus
Dr. Sontising’s research has spanned computational chemistry, analytical method development, and biomedical applications. His doctoral work contributed to the understanding of crystal structures, intermolecular forces, and novel phases of elemental and molecular systems. In industry, he developed high-throughput analytical methods that accelerated workflows and improved efficiency in biomaterial research. At Mount Sinai, his focus has shifted toward metabolomics, lipidomics, and mass spectrometry imaging, where he is developing novel methods to study the chemical architecture of the brain. By combining advanced instrumentation with computational pipelines in R and Python, he has been able to elucidate metabolic pathways in neurological disease models, reinforcing the role of chemistry in unraveling complex biological processes.
Scholarly Publications
His contributions to the scientific community are reflected in a body of published work spanning computational chemistry, crystallography, photomechanical materials, polymerization mechanisms, and spatial metabolomics. His publications in journals such as Chemical Science, CrystEngComm, and Physical Review Materials highlight his ability to merge theoretical approaches with practical applications. Recent work in spatial metabolomics protocols has further expanded the methodological toolkit available to researchers studying brain metabolism, representing a bridge between chemical sciences and medical research.
Accolades and Recognition
Throughout his academic and professional career, Dr. Sontising has been recognized for his commitment to both research excellence and teaching impact. His role as a mentor, educator, and scientific contributor has been acknowledged through opportunities to supervise students, lead laboratory teams, and co-author impactful studies. His ability to secure and contribute to grant-funded projects demonstrates not only trust in his expertise but also recognition of his potential to shape innovative research directions.
Impact and Influence
The impact of his work can be seen in multiple spheres—students he has mentored, laboratories he has organized and modernized, and scientific knowledge he has advanced through publications and method development. By linking fundamental chemistry with applied biomedical research, Dr. Sontising has influenced how metabolomics and mass spectrometry are utilized in the study of neurological disorders. His interdisciplinary perspective allows for meaningful collaborations across chemistry, biology, and medicine, creating pathways for innovation that resonate beyond a single discipline.
Legacy and Future Contributions
Looking forward, Dr. Sontising is positioned to make lasting contributions at the intersection of chemistry and neuroscience. His ongoing development of novel imaging and analytical methods will continue to expand the understanding of brain chemistry and its relationship to disease. As an educator, he remains committed to shaping the next generation of scientists by integrating critical thinking, computational literacy, and practical laboratory expertise into the learning process. His legacy will likely be defined by both the scientific advancements he enables and the careers he helps foster, ensuring his influence endures in both the laboratory and the classroom.
Publications
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Theoretical study on the mechanism and kinetics of ring-opening polymerization of cyclic esters initiated by tin(II) n-butoxide — C. Sattayanon, W. Sontising, J. Jitonnom, P. Meepowpan, W. Punyodom, … — 2014
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Structural switching in self-assembled metal–ligand helicate complexes via ligand-centered reactions — L.R. Holloway, H.H. McGarraugh, M.C. Young, W. Sontising, G.J.O. Beran, … — 2016
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Theoretical predictions suggest carbon dioxide phases III and VII are identical — W. Sontising, Y.N. Heit, J.L. McKinley, G.J.O. Beran — 2017
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Effect of halogen substitution on energies and dynamics of reversible photomechanical crystals based on 9-anthracenecarboxylic acid — T.J. Gately, W. Sontising, C.J. Easley, I. Islam, R.O. Al-Kaysi, G.J.O. Beran, … — 2021
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Theoretical study of the hydrogen abstraction of substituted phenols by nitrogen dioxide as a source of HONO — A. Shenghur, K.H. Weber, N.D. Nguyen, W. Sontising, F.M. Tao — 2014
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Effects of alkoxide alteration on the ring-opening polymerization of ε-caprolactone initiated by n-Bu3SnOR: a DFT study — C. Sattayanon, W. Sontising, W. Limwanich, P. Meepowpan, W. Punyodom, … — 2015
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Protocol for spatial metabolomics and isotope tracing in the mouse brain — W. Sontising, F. Yanchik-Slade, C. Rodriguez-Navas, M.A. Hossen, … — 2025
Conclusion
Dr. Sontising’s career demonstrates a rare combination of scientific versatility, teaching excellence, and interdisciplinary innovation. His ability to move fluidly from theoretical chemistry to practical laboratory applications, and finally to biomedical research, underscores a dynamic approach that bridges multiple fields of science. He continues to shape the future of chemistry and neuroscience by developing novel analytical tools while inspiring the next generation of scientists through mentorship and education. His enduring influence lies in both his contributions to advancing knowledge and his commitment to empowering others, marking him as a researcher and educator of lasting impact.