Zewen Cheng | Clinical Medicine | Young Scientist Award

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Dr. Zewen Cheng | Clinical Medicine | Young Scientist Award

Dr. Zewen Cheng, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine,Ā  China.

Zewen Chengā€™s career is a testament to his dedication to thoracic surgery, combining expertise in both Western and Traditional Chinese medicine. His academic excellence, professional experience, and research contributions highlight his unwavering commitment to advancing patient care. As a skilled surgeon and educator, he continues to make a significant impact in the medical community. Moving forward, his focus on innovation and mentorship will ensure that his contributions leave a lasting mark on the field of thoracic surgery, inspiring future generations of medical professionals.

Profile

Scopus

 

šŸŽ“ Early Academic Pursuits

Zewen Cheng embarked on his medical journey with a passion for thoracic surgery, earning a Master of Medicine in Thoracic Surgery from Soochow University in Suzhou, China. Graduating in 2019, he dedicated himself to mastering the complexities of thoracic diseases, developing a strong foundation in both clinical and surgical practices. His academic years were marked by rigorous training and an unwavering commitment to patient care, setting the stage for his future contributions to the medical field.

šŸ„ Professional Endeavors

After completing his degree, Zewen Cheng undertook a comprehensive three-year residency at The First Affiliated Hospital of Soochow University. From July 2019 to June 2022, he refined his expertise in thoracic surgery, gaining invaluable hands-on experience in clinical diagnostics, patient management, and surgical procedures. His tenure in the residency program enabled him to work closely with senior specialists, tackling complex cases and honing his skills. In September 2022, he advanced to the role of Attending Physician at Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, where he seamlessly integrates Western and Traditional Chinese medical treatments to provide holistic patient care.

šŸ”¬ Contributions and Research Focus

Zewen Cheng is deeply invested in the evolving landscape of thoracic surgery. His research interests span innovative surgical techniques, minimally invasive procedures, and the integration of Traditional Chinese Medicine (TCM) in thoracic disease management. With proficiency in data analysis software such as R and SPSS, he actively contributes to medical research, utilizing statistical methodologies to enhance clinical decision-making. His work emphasizes the importance of interdisciplinary approaches in improving patient outcomes and advancing the field of thoracic surgery.

šŸ† Accolades and Recognition

Throughout his medical career, Zewen Cheng has been recognized for his dedication and expertise in thoracic surgery. Successfully completing the standardized residency training at The First Affiliated Hospital of Soochow University, he demonstrated exceptional skill and commitment to surgical excellence. His fluency in Medical English (CET-6) has enabled him to collaborate effectively with international medical professionals, further expanding his impact within the global medical community.

šŸ’Ŗ Impact and Influence

As an Attending Physician, Zewen Cheng plays a crucial role in supervising and training junior doctors, fostering the next generation of thoracic surgeons. His ability to blend traditional and modern medical practices ensures that patients receive comprehensive treatment tailored to their specific needs. His contributions extend beyond direct patient care, as he actively participates in multidisciplinary teams, shaping the future of thoracic surgery through collaborative innovation and knowledge sharing.

šŸŒŸ Legacy and Future Contributions

With a strong foundation in both clinical practice and research, Zewen Cheng aspires to push the boundaries of thoracic surgery through continuous learning and innovation. His commitment to integrating Traditional Chinese Medicine with contemporary surgical techniques presents new avenues for patient care and treatment efficacy. Looking ahead, he envisions contributing to groundbreaking research, refining surgical methodologies, and mentoring future medical professionals, leaving a lasting legacy in the field of thoracic surgery.

 

Publication

Title: Exploring the Causal Relationship Between Frailty and Chronic Obstructive Pulmonary Disease: Insights From Bidirectional Mendelian Randomization and Mediation Analysis
Authors: Zewen Cheng, Jian Wu, Chun Xu, Xiaokun Yan
Year: 2025

 

šŸ† Conclusion

Zewen Cheng is a strong candidate for the Young Scientist Award, given his clinical expertise, innovative approach to medicine, and commitment to training future surgeons. Strengthening his research impact and expanding international collaborations would further solidify his position as a leading young scientist in thoracic surgery.

 

 

Jeffrey Holt | Hearing and Sensory Transduction | Lifetime achievement Award

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Prof. Jeffrey Holt | Hearing and Sensory Transduction | Lifetime achievement Award

Prof. Jeffrey Holt,Ā  Harvard Medical School / Boston Children’s Hospital, United States.

Dr. Jeffrey R. Holt is a distinguished scientist whose groundbreaking contributions to auditory neuroscience and inner ear physiology have significantly advanced the field of otolaryngology. Currently serving as a Professor of Otolaryngology and Neurology at Boston Childrenā€™s Hospital and Harvard Medical School, Dr. Holt’s career is marked by an unwavering commitment to understanding the molecular and physiological mechanisms underlying hearing and balance disorders.

Profile

Google Scholar

 

Early Academic Pursuits šŸŽ“

Born in Buffalo, NY, Dr. Holt’s passion for science was evident early in his academic journey. He earned his Bachelor of Science degree in Biology from Wofford College in 1986, laying a strong foundation in the life sciences. His quest for knowledge led him to the University of Rochester, where he pursued a Masterā€™s degree in Physiology in 1992, followed by a Ph.D. in Physiology in 1995. His doctoral research provided deep insights into the intricate workings of sensory physiology, setting the stage for his future research endeavors in auditory neuroscience.

Professional Endeavors and Leadership šŸ‘©ā€šŸ’¼

Following his Ph.D., Dr. Holt embarked on postdoctoral training at Harvard Medical School, Massachusetts General Hospital, and the Howard Hughes Medical Institute. His extensive training in neurobiology enabled him to transition into academic roles, beginning as an Instructor in Neurobiology at Harvard Medical School and Massachusetts General Hospital from 1999 to 2001. He later joined the University of Virginia as an Assistant Professor of Neuroscience, where he progressed to Associate Professor before returning to Harvard in 2011. Since 2016, he has held the esteemed position of Professor of Otolaryngology at Boston Childrenā€™s Hospital and Harvard Medical School, as well as a faculty affiliation with the Harvard-MIT Health Sciences and Technology (HST) program.

Contributions and Research Focus šŸŒ

Dr. Holt’s pioneering research has been instrumental in decoding the molecular basis of hearing and balance disorders. His work focuses on sensory hair cells of the inner ear, aiming to uncover the genetic and physiological mechanisms that contribute to hearing loss. His studies have explored ion channel function, hair cell mechanotransduction, and gene therapy approaches for hereditary deafness. His innovative research has opened new avenues for therapeutic interventions, including the development of gene therapies targeting Usher syndrome and other genetic hearing disorders.

Accolades and Recognition šŸ†

Throughout his career, Dr. Holt has been widely recognized for his contributions to auditory science. He has played key leadership roles in prestigious scientific organizations, serving as Chair of the Usher Syndrome Society Scientific Advisory Committee and Co-Chair of major international conferences such as the Keystone Conference on Sensory Systems and the New York Academy of Sciences Meeting. His service on various NIH and NIDCD advisory committees reflects his influence in shaping national research priorities in hearing and balance disorders.

Impact and Influence on Scientific Community šŸŒ

Dr. Holtā€™s impact extends beyond research, as he has been a dedicated mentor and educator throughout his career. He has guided numerous graduate students and postdoctoral fellows, serving on thesis and qualifying exam committees at Harvard Medical School. As a course director and research mentor, he has played a crucial role in training the next generation of auditory neuroscientists. His leadership in academic and scientific communities has helped bridge the gap between fundamental research and clinical applications in hearing restoration.

Legacy and Future Contributions šŸ’Ŗ

With a legacy rooted in groundbreaking discoveries and scientific leadership, Dr. Holt continues to push the boundaries of auditory neuroscience. His ongoing research in gene therapy for hereditary deafness holds the promise of transforming lives through novel treatments for hearing loss. As a visionary in the field, his work is set to inspire future advancements in otolaryngology, offering hope to millions affected by hearing and balance disorders worldwide. His dedication to research, education, and clinical impact ensures that his contributions will leave a lasting imprint on auditory science for generations to come.

 

Publication

  • TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells
    Authors: DP Corey, J GarcĆ­a-AƱoveros, JR Holt, KY Kwan, SY Lin, MA Vollrath, …
    Year: 2004

 

  • Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents
    Authors: X Gao, Y Tao, V Lamas, M Huang, WH Yeh, B Pan, YJ Hu, JH Hu, …
    Year: 2018

 

  • Mechanotransduction in mouse inner ear hair cells requires transmembrane channelā€“like genes
    Authors: Y Kawashima, GSG GĆ©lĆ©oc, K Kurima, V Labay, A Lelli, Y Asai, …
    Year: 2011

 

  • TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear
    Authors: B Pan, GS GĆ©lĆ©oc, Y Asai, GC Horwitz, K Kurima, K Ishikawa, …
    Year: 2013

 

  • Continuous evolution of base editors with expanded target compatibility and improved activity
    Authors: BW Thuronyi, LW Koblan, JM Levy, WH Yeh, C Zheng, GA Newby, …
    Year: 2019

 

  • Differential distribution of stem cells in the auditory and vestibular organs of the inner ear
    Authors: K Oshima, CM Grimm, CE Corrales, P Senn, R Martinez Monedero, …
    Year: 2007

 

  • A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells
    Authors: JR Holt, SKH Gillespie, DW Provance, K Shah, KM Shokat, DP Corey, …
    Year: 2002

 

  • A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear
    Authors: LD Landegger, B Pan, C Askew, SJ Wassmer, SD Gluck, A Galvin, …
    Year: 2017

 

  • Calcium imaging of single stereocilia in hair cells: localization of transduction channels at both ends of tip links
    Authors: W Denk, JR Holt, GMG Shepherd, DP Corey
    Year: 1995

 

  • TMC1 forms the pore of mechanosensory transduction channels in vertebrate inner ear hair cells
    Authors: B Pan, N Akyuz, XP Liu, Y Asai, C Nist-Lund, K Kurima, BH Derfler, …
    Year: 2018

 

Conclusion šŸŽÆ

Dr. Holtā€™s contributions to auditory neuroscience have revolutionized the field, bridging fundamental research with clinical applications. His groundbreaking work in gene therapy holds immense potential for treating hereditary hearing disorders, making a profound impact on global healthcare. As a researcher, educator, and leader, his legacy will continue to inspire innovation in otolaryngology and improve the lives of individuals affected by hearing and balance impairments for generations to come.