Hongrui Meng | Neurodegenerative disease | Excellence in Research Award

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Prof. Dr. Hongrui Meng | Neurodegenerative disease | Excellence in Research Award

Prof. Dr. Hongrui Meng,  Institute of Neuroscience, Soochow University, China.

Dr. Hongrui Meng is a highly accomplished neuroscientist whose academic path began with a Ph.D. in Behavioural Neuroscience from Hamamatsu University School of Medicine in Japan. He later conducted postdoctoral research in molecular neurobiology and human genetics at Juntendo University, Tokyo. Currently a professor at the Institute of Neuroscience, Soochow University, Dr. Meng leads a research team dedicated to uncovering the molecular and mitochondrial mechanisms underlying Parkinson’s disease and ALS. His work spans high-impact research projects funded by JSPS, NSFC, and other prestigious bodies. In addition to numerous scientific publications, he has contributed to diagnostic innovation through patented miRNA detection methods. His influence extends beyond academia through translational applications such as wearable technologies for Parkinson’s symptom monitoring.

Profile

Orcid

🎓 Early Academic Pursuits

Dr. Hongrui Meng began his distinguished academic journey in the field of neuroscience by earning his Ph.D. in Behavioural Neuroscience from the prestigious Hamamatsu University School of Medicine in Japan. His early education and training laid a strong foundation in experimental neuroscience, with a focus on the behavioral manifestations of neurodegenerative conditions. These formative years not only sharpened his scientific curiosity but also equipped him with the cross-disciplinary expertise to address complex neurological questions.

🧠 Professional Endeavors

Following his doctoral studies, Dr. Meng advanced his specialization through postdoctoral training in molecular neurobiology and human genetics at Juntendo University in Tokyo. There, he immersed himself in high-level research focusing on the genetic underpinnings of neurological disorders. His competence and dedication soon earned him a faculty appointment as an Assistant Professor in the Department of Research for Neurodegenerative Diseases and Dementia. His professional arc reached a significant milestone in 2020 when he was promoted to Full Professor and moved to the Institute of Neuroscience at Soochow University, where he now leads the Laboratory of Molecular Neurology.

🧬 Contributions and Research Focus

Dr. Meng’s scientific contributions center on the molecular mechanisms of Parkinson’s disease and amyotrophic lateral sclerosis (ALS). His research bridges mitochondrial dysfunction, alpha-synuclein aggregation, and neurodegeneration. He has completed pivotal studies supported by the Japan Society for the Promotion of Science and the Takeda Pharmaceutical Foundation, delving into the role of CHCHD2 gene mutations and mitochondrial pathways. His ongoing projects funded by the National Natural Science Foundation of China (NSFC) explore mitochondrial unfolded protein responses (mtUPR), while another innovative project in Suzhou focuses on wearable technology for monitoring Parkinson’s disease symptoms—demonstrating his commitment to translational and patient-centered neuroscience.

🔬 Innovation and Scientific Output

A notable innovator, Dr. Meng has made strides in molecular diagnostic technologies. His work has led to the development of high-throughput RT-qPCR-based methods for detecting primary and precursor miRNAs, contributing to enhanced genetic analysis of neurodegenerative disorders. He holds a patent granted in South Africa and another under process in China, underscoring his role at the intersection of research and technology. Furthermore, his publications in highly regarded journals like Current Issues in Molecular Biology and Cell Communication and Signaling reflect a consistent record of impactful findings that inform both fundamental neuroscience and clinical approaches.

🏅 Accolades and Recognition

Dr. Meng’s ascent in the academic community has been marked by numerous grants, including multiple from the JSPS and NSFC, attesting to the trust placed in his research vision by top funding bodies. While a formal list of awards may be under-documented, his rapid progression from postdoctoral fellow to professor and research team leader in less than a decade speaks volumes about his recognition among peers and institutional leadership. His leadership in multi-disciplinary and international collaborations is an implicit accolade of his scientific reliability and visionary perspective.

🌍 Impact and Influence

Through his groundbreaking work on mitochondrial mechanisms and neurodegeneration, Dr. Meng is helping to reshape current understanding of Parkinson’s disease pathophysiology. His investigations into alpha-synucleinopathy and microglial disruption have provided fresh insights into cellular degeneration and neuroimmune interactions. Beyond academia, his involvement in developing wearable diagnostic tools highlights his drive to impact patient lives directly. As a consultant on neuroprotective treatments such as PD-018/19, he bridges the academic and pharmaceutical worlds to accelerate therapeutic discovery.

🔮 Legacy and Future Contributions

Looking forward, Dr. Meng is poised to be a leading figure in neurogenetic diagnostics and therapeutic innovation. His laboratory at Soochow University serves as an incubator for future discoveries in neurodegenerative disease mechanisms, and his continued work in mitochondrial research promises to inform emerging therapies. With a growing publication record, international patents, and a robust research pipeline, Dr. Meng’s legacy will be one of bridging basic neuroscience with clinical application—paving the way for novel interventions and a better understanding of brain disorders in the molecular era.

Publication

 

  • Title: Dicer Is Involved in Cytotoxicity and Motor Impairment Induced by TBPH Deficiency
    Authors: Xiang Long, Yijie Wang, Hongrui Meng
    Year: 2025

 

  • Title: Transcriptomic analysis of lipid metabolism genes in Alzheimer’s disease: highlighting pathological outcomes and compartmentalized immune status
    Authors: Sun Y., Zhang Y., Jiang M., Long X., Miao Y., Du H., Zhang T., Meng H., Ma X.
    Year: 2024

 

  • Title: CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis
    Authors: Aya Ikeda, Hongrui Meng, Daisuke Taniguchi, Muneyo Mio, Manabu Funayama, Kenya Nishioka, Mari Yoshida, Yuanzhe Li, Hiroyo Yoshino, Tsuyoshi Inoshita et al.
    Year: 2024

 

  • Title: TDP-43 mutations-induced defects in miRNA biogenesis and cytotoxicity by differentially obstructing Dicer activity in Drosophila and in vitro
    Authors: Xiang Long, Mengni Jiang, Yongzhen Miao, Huanhuan Du, Ting Zhang, Zhuoya Ma, Jiao Li, Chunfeng Liu, Hongrui Meng
    Year: 2024

 

  • Title: A Simple Technique to Assay Locomotor Activity in Drosophila
    Authors: Long X., Du H., Jiang M., Meng H.
    Year: 2023

 

  • Title: Functional MHCI deficiency induces ADHD-like symptoms with increased dopamine D1 receptor expression
    Authors: Meng H.-R., Suenaga T., Edamura M., Nakahara D., Murakami G., Fukuda A., Ishida Y.
    Year: 2021

 

  • Title: Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease
    Authors: Imai Y., Hattori N., Inoshita T., Shiba-Fukushima K., Meng H., Hara K.Y., Sawamura N.
    Year: 2019

 

  • Title: Mutations in CHCHD2 cause α-synuclein aggregation
    Authors: Ikeda A., Nishioka K., Takanashi M., Li Y., Mori A., Okuzumi A., Izawa N., Ishikawa K.-I., Funayama M., Imai Y. et al.
    Year: 2019

 

  • Title: Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling
    Authors: Mori A., Hatano T., Koinuma T., Kubo S.-I., Spratt S., Yamashita C., Okuzumi A., Imai Y., Hattori N., Inoshita T. et al.
    Year: 2019

 

  • Title: Twin CHCH proteins, CHCHD2, and CHCHD10: Key molecules of Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementia
    Authors: Imai Y., Hattori N., Meng H., Shiba-Fukushima K.
    Year: 2019

 

🧾 Conclusion

Dr. Hongrui Meng’s career reflects a dynamic blend of academic excellence, molecular research innovation, and translational neuroscience. His scientific endeavors have not only enriched the understanding of neurodegenerative diseases but have also paved the way for novel diagnostic and therapeutic strategies. With a growing portfolio of impactful research, patents, and leadership in neurobiology, Dr. Meng stands out as a driving force in the global fight against neurological disorders. His work promises continued contributions to neuroscience with lasting influence on both scientific knowledge and patient care.

 

Edyta GLOGOWSKA | Cell Metabolism | Best Researcher Award

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Dr. Edyta Glogowska | Cell Metabolism | Best Researcher Award

Dr.  Edyta Glogowska, CNRS-IPMC-UniCA,  France.

Dr. Edyta Glogowska is a passionate and accomplished biomedical researcher with a strong academic background in biotechnology and life sciences. From her early beginnings in dental engineering to earning a PhD in red blood cell physiology from the University Pierre and Marie Curie, her academic journey reflects a deep commitment to advancing human health through science. Her postdoctoral research at the Institute of Molecular and Cellular Pharmacology (IPMC) highlights her expertise in cell physiology, electrophysiology, and molecular biology, with a special focus on macrophage Piezo1 channels and their role in atherosclerosis. She is a skilled communicator and team collaborator, recognized for her academic excellence and contributions to hematology and immunopathology.

Profile

Scopus

🎓 Early Academic Pursuits

Dr. Edyta Glogowska’s journey into the world of life sciences began with a strong foundation in biotechnology and medical sciences. She earned her Master of Engineering in Biotechnology Processing from Wroclaw University of Science and Technology, where she graduated with highest honors. Even earlier, she had already laid a unique cornerstone for her biomedical interests through specialized training as a Dental Engineer at the Marie Curie Medical Vocational School. Her pursuit of deeper scientific knowledge led her to France, where she undertook her PhD in Biological and Life Sciences at the University Pierre and Marie Curie, Paris VI. Conducted at the prestigious Station Biologique in Roscoff, her doctoral research focused on red blood cell physiology and was awarded with the highest honors—a testament to her early dedication and scientific promise.

🔬 Professional Endeavors

Dr. Glogowska’s professional career has been marked by a steadfast commitment to cell and molecular biology, electrophysiology, and the biochemistry of proteins. Her postdoctoral research at the Institute of Molecular and Cellular Pharmacology (IPMC) in Sophia Antipolis (2021–2024) showcases her hands-on expertise with mice experimentation and patch-clamp techniques, placing her at the cutting edge of biomedical research. Working under the guidance of Dr. Eric Honoré, she explored the role of macrophage Piezo1 channels regulated by lipids, a study with far-reaching implications in understanding and potentially treating atherosclerosis.

🧬 Contributions and Research Focus

Throughout her academic and postdoctoral years, Dr. Glogowska has focused her research on the physiology and pathophysiology of cells, particularly red blood cells and immune cells like macrophages. Her interest lies in understanding how cellular mechanisms contribute to broader medical conditions, such as cardiovascular diseases. By integrating electrophysiology with molecular biology, she brings a comprehensive approach to biomedical questions, bridging the gap between basic research and therapeutic application. Her work on Piezo1 not only contributes to our understanding of mechanotransduction in macrophages but also holds promise for future translational research.

🏅 Accolades and Recognition

Dr. Glogowska’s scholarly excellence has been consistently recognized. She graduated with highest honors both for her Master’s and PhD degrees, a rare academic distinction that underscores her dedication and intellectual rigor. She has also been an active member of the French Society of Hematology, aligning herself with leading experts in her field and staying abreast of the latest developments in blood cell research. These accolades reflect her respected standing within the scientific community.

🌍 Impact and Influence

Beyond technical expertise, Dr. Glogowska is praised for her team coordination and communication skills, qualities that have enabled her to contribute meaningfully to collaborative research environments. Her scientific efforts in understanding lipid–ion channel interactions in macrophages directly influence the broader field of cardiovascular immunology. By elucidating the role of Piezo1 channels in inflammatory processes, her research provides foundational knowledge that can inspire novel pharmacological interventions.

🔎 Legacy and Future Contributions

Dr. Glogowska continues to strive toward a future where her research leads to medical breakthroughs in inflammation and cardiovascular disease. She is particularly interested in translational science, where laboratory discoveries transition into clinical applications. Her strong background in biotechnology, dentistry, and molecular biology uniquely equips her to explore cross-disciplinary challenges in human health. As she advances, she aims to bridge research with clinical solutions, contributing to a legacy of innovation in life sciences.

Publication

Title: Potentiation of macrophage Piezo1 by atherogenic 7-ketocholesterol
Authors: Edyta Glogowska, Gregor P. Jose, Ana Rita Dias Araújo, Laurent Yvan-Charvet, Éric R. Honoré
Year: 2025

Title: Piezo1 in PASMCs: Critical for Hypoxia-Induced Pulmonary Hypertension Development
Authors: Fenja Knoepp, Shariq Abid, Amal Houssaïni, Éric R. Honoré, Serge Adnot
Year: 2025

Title: Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion
Authors: Rakhee Lohia, Benoit Allegrini, Laurence Berry, Éric R. Honoré, Kai Wengelnik
Year: 2023

Title: A machine-learning algorithm integrating baseline serum proteomic signatures predicts exercise responsiveness in overweight males with prediabetes
Authors: Candela Diaz-Canestro, Jiarui Chen, Yan Liu, Michael Andrew Tse, Aimin Xu
Year: 2023

Title: Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects
Authors: Kang Chen, Lai Yee Cheong, Yuan Gao, Hannah Xiaoyan Hui, Aimin Xu
Year: 2022

Title: Author Correction: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
Authors: Shengpeng Wang, Shuang Cao, Malika Arhatte, Éric R. Honoré, Stefan Offermanns
Year: (Correction Published) — Likely 2021 or 2022

Title: Piezo1 and Piezo2 foster mechanical gating of K2P channels
Authors: Edyta Glogowska, Malika Arhatte, Franck C. Chatelain, Amanda Jane Patel, Éric R. Honoré
Year: 2021

Title: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
Authors: Shengpeng Wang, Shuang Cao, Malika Arhatte, Éric R. Honoré, Stefan Offermanns
Year: 2020

Title: Piezo Ion Channels in Cardiovascular Mechanobiology
Authors: Dominique Douguet, Amanda Jane Patel, Aimin Xu, Paul Michel Vanhoutte, Éric R. Honoré
Year: (Not explicitly stated, likely ~2020 based on context)

Title: TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells
Authors: Malika Arhatte, Gihan S. Gunaratne, Charbel El Boustany, Éric R. Honoré, Amanda Jane Patel
Year: 2019

 

 

✅ Conclusion

Driven by curiosity and guided by precision, Dr. Glogowska continues to make meaningful strides in biomedical research. Her work stands at the intersection of basic science and medical application, with the potential to influence future therapeutic strategies for cardiovascular and inflammatory diseases. With her versatile skill set and visionary approach, she is well-positioned to leave a lasting impact on the scientific and medical communities. As she moves forward, Dr. Glogowska aspires to further bridge laboratory discoveries with clinical innovations, fostering a legacy of scientific excellence and translational breakthroughs.

 

John Vincent Sanchez Orti | Biomarkers in Neurocognition | Young Scientist Award

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Dr. John Vincent Sanchez Orti | Biomarkers in Neurocognition | Young Scientist Award

Dr. Joan Vicent Sánchez Ortí, Health research institute,  Spain.

Joan Vicent Sánchez Ortí is a Clinical Psychologist and Neuropsychologist currently working as a Research Technician at the Instituto de Investigación Sanitaria – INCLIVA. He is also a predoctoral researcher affiliated with CIBERSAM (Group 24, Universitat de València). His academic background includes a Bachelor’s degree in Psychology (2016), a Master’s in General Health Psychology (2019), and a Master’s in Basic and Applied Neurosciences (2021), all from Universitat de València. He is currently pursuing a Ph.D. in Medicine.

Profile

Google Scholar

Orcid

🧠 A Passion for Understanding the Mind

Joan Vicent Sánchez Ortí was born on August 6, 1994, with an innate curiosity about the complexities of human cognition. From an early age, he displayed a deep interest in psychology and neuroscience, which led him to pursue an academic path dedicated to unraveling the mysteries of the brain. His journey began at the Universitat de València, where he obtained his degree in Psychology in 2016. Motivated by his growing fascination with neuropsychology, he continued his studies, earning a Master’s in General Health Psychology in 2019 and a Master’s in Basic and Applied Neurosciences in 2021. His dedication to advancing medical science led him to enroll in an official Doctorate Program in Medicine at the same institution.

🏥 Bridging Psychology and Neuroscience in Professional Practice

Currently serving as a Neuropsychologist and Research Technician at the Health Research Institute (INCLIVA) in Spain, Joan Vicent plays a vital role in understanding cognitive impairments associated with severe mental disorders. His affiliation with the Biomedical Research Center in Mental Health Network (CIBERSAM) – Group 24 at the Universitat de València has allowed him to contribute significantly to groundbreaking studies. His expertise lies in assessing neurocognitive deficits, biomarkers, and epigenetic factors, aiming to enhance the diagnosis and treatment of psychiatric and neurological conditions.

🔬 Advancing Research in Neurocognitive Deficits and Mental Health

Joan Vicent’s research delves into the intricate connections between brain function, cognition, and mental health. His studies focus on identifying early biomarkers of cognitive decline, exploring epigenetic influences, and evaluating social functioning and quality of life in patients suffering from severe mental disorders. His contributions have been instrumental in improving the understanding of conditions such as schizophrenia, bipolar disorder, and neurodegenerative diseases, providing valuable insights for clinical interventions.

🏆 Recognized for Excellence in Neuroscience and Psychology

Through his commitment to scientific discovery, Joan Vicent has garnered recognition in the field of neuroscience and psychology. His contributions to neuropsychology and mental health research have positioned him as a promising figure in cognitive science. His work is widely acknowledged for its impact on the development of new therapeutic approaches and diagnostic techniques. With a strong academic and research background, he continues to be an influential voice in the study of cognitive impairment.

🌍 Impacting Lives Through Mental Health Research

Beyond academic achievements, Joan Vicent’s work has real-world implications, improving the quality of life for individuals facing cognitive challenges. His research contributes to developing more effective treatments, enhancing diagnostic accuracy, and fostering a better understanding of mental disorders. Through his role at INCLIVA and CIBERSAM, he actively collaborates with interdisciplinary teams, ensuring that his findings are translated into clinical practice, ultimately benefiting patients and healthcare professionals alike.

🚀 Paving the Way for Future Innovations in Neuropsychology

With a strong foundation in psychology, neuroscience, and medicine, Joan Vicent remains dedicated to pushing the boundaries of cognitive research. His ongoing studies aim to integrate cutting-edge techniques in neuroimaging, genetics, and artificial intelligence to refine the understanding of neurocognitive disorders. His ambition is to contribute to the development of personalized medicine, where treatments are tailored to an individual’s neurobiological and psychological profile, revolutionizing mental healthcare.

🔮 A Vision for a Healthier, Cognitively Resilient Future

Looking ahead, Joan Vicent Sánchez Ortí envisions a world where mental health is better understood, diagnosed, and treated with precision. His dedication to neuropsychology and cognitive research will continue to shape the future of mental healthcare, inspiring new generations of scientists and clinicians. As he advances in his career, his unwavering commitment to improving lives through research stands as a testament to his passion and perseverance in the field of neuroscience.

Publication

  • Manual motor speed dysfunction as a neurocognitive endophenotype in euthymic bipolar disorder patients and their healthy relatives. Evidence from a 5-year follow-up study
    P Correa-Ghisays, V Balanzá-Martínez, G Selva-Vera, J Vila-Francés, …
    2017

 

  • Grip Strength, Neurocognition, and social functioning in people With Type-2 diabetes mellitus, major depressive disorder, bipolar disorder, and schizophrenia
    M Aliño-Dies, JV Sanchez-Orti, P Correa-Ghisays, V Balanzá-Martinez, …
    2020

 

  • Visual memory dysfunction as a neurocognitive endophenotype in bipolar disorder patients and their unaffected relatives. Evidence from a 5-year follow-up Valencia study
    P Correa-Ghisays, JV Sánchez-Ortí, R Ayesa-Arriola, E Setién-Suero, …
    2019

 

  • Specific metabolic syndrome components predict cognition and social functioning in people with type 2 diabetes mellitus and severe mental disorders
    JV Sanchez‐Orti, V Balanzá‐Martinez, P Correa‐Ghisays, G Selva‐Vera, …
    2022

 

  • Immune–Inflammatory Biomarkers Predict Cognition and Social Functioning in Patients With Type 2 Diabetes Mellitus, Major Depressive Disorder, Bipolar Disorder, and …
    M Garés-Caballer, JV Sánchez-Ortí, P Correa-Ghisays, …
    2022

 

  • Probiotic, prebiotic, synbiotic and fermented food supplementation in psychiatric disorders: A systematic review of clinical trials
    C Ribera, JV Sánchez-Ortí, G Clarke, W Marx, S Mörkl, …
    2024

 

  • Transdiagnostic neurocognitive deficits in patients with type 2 diabetes mellitus, major depressive disorder, bipolar disorder, and schizophrenia: A 1-year follow-up study
    P Correa-Ghisays, JV Sanchez-Orti, V Balanza-Martinez, G Selva-Vera, …
    2022

 

  • Inflammation and lipid metabolism as potential biomarkers of memory impairment across type 2 diabetes mellitus and severe mental disorders
    JV Sanchez-Orti, P Correa-Ghisays, V Balanza-Martinez, G Selva-Vera, …
    2023

 

  • MICEmi: A method to identify cognitive endophenotypes of mental illnesses
    P Correa-Ghisays, JV Sanchez-Orti, V Balanza-Martinez, I Fuentes-Dura, …
    2022

 

  • Specific immune-inflammatory profiles and neurocognitive deficits predict illness trajectories in people with type 2 diabetes mellitus or psychiatric disorders
    JV Sanchez-Orti, P Correa-Ghisays, V Balanza-Martinez, G Selva-Vera, …
    2025

 

Conclusion 🎯

Joan Vicent Sánchez Ortí’s dedication to neuroscience and mental health research positions him as an influential figure in the field. His expertise bridges psychology, medicine, and genetics, offering innovative solutions for cognitive disorders. With a strong commitment to improving lives through research, his work has already made a meaningful impact and will continue to shape the future of mental healthcare, neuropsychology, and personalized medicine. As he advances in his career, his passion and contributions will undoubtedly lead to groundbreaking discoveries in cognitive science.