Magdalena Budzyń | Immunology | Women Researcher Award

Assist. Prof. Dr. Magdalena Budzyń | Immunology | Women Researcher Award

Assist. Prof. Dr. Magdalena Budzyń, Poznan University of Medical Sciences, Poland.

Dr. Magdalena Budzyń is an accomplished researcher and educator specializing in cardiovascular diseases and laboratory diagnostics. With a strong academic foundation from Poznan University of Medical Sciences, she earned her Ph.D. in Medical Sciences and later achieved the prestigious habilitated doctor qualification. Her research focuses on endothelial damage markers and their role in cardiovascular conditions, contributing valuable insights into disease mechanisms. As an Assistant Professor, she has been dedicated to both scientific discovery and mentoring future medical professionals.

Profile

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Early Academic Pursuits 🎓

Born on April 4, 1982, Dr. Magdalena Budzyń embarked on her academic journey with a passion for medical sciences. Her educational path began at Poznan University of Medical Sciences, where she pursued an in-depth study of laboratory diagnostics. She completed her Ph.D. in Medical Sciences between 2009 and 2013, focusing on the intricate balance between leukocyte elastase and its inhibitor alpha1-antitrypsin in chronic venous insufficiency. With an insatiable curiosity for cardiovascular research, she further advanced her academic credentials by earning a habilitated doctor degree in 2022, exploring circulating markers of endothelial damage and their clinical implications in cardiovascular diseases.

Professional Endeavors 🏅

Dr. Budzyń’s professional career has been a testament to her dedication to medical research and education. She has been an integral part of Poznan University of Medical Sciences since 2007, serving as an Assistant Professor. Prior to that, she gained valuable experience at Poznan Veterinary Institute as a Technical Assistant, where she honed her laboratory and analytical skills. Her expertise in laboratory medicine and medical chemistry has made her a respected academic in her field, contributing significantly to both research and teaching.

Contributions and Research Focus 🔬

Her research primarily revolves around cardiovascular diseases, with a particular emphasis on endothelial damage markers. By investigating the role of these biomarkers, she has provided critical insights into the pathophysiology of vascular disorders. Her work has contributed to the understanding of chronic venous insufficiency and how leukocyte elastase imbalance impacts disease progression. Additionally, her studies in laboratory diagnostics have strengthened the role of clinical biomarkers in predicting and managing cardiovascular conditions.

Accolades and Recognition 🏆

Dr. Budzyń’s academic excellence has been recognized through her habilitated doctor qualification, a prestigious milestone in her career. Her contributions to medical sciences have been acknowledged within the scientific community, as she continues to shape the field of cardiovascular research. Her role as an educator and mentor further amplifies her influence, guiding students toward meaningful research endeavors in laboratory medicine and diagnostics.

Impact and Influence 🌍

Beyond academia, Dr. Budzyń’s research has a profound impact on the medical field, particularly in improving diagnostic tools for cardiovascular diseases. Her findings contribute to enhanced patient care by identifying key biomarkers that aid in early disease detection and treatment planning. She actively collaborates with researchers and medical professionals, ensuring that her work bridges the gap between scientific discovery and clinical application.

publication

  • Significance of the monocyte CCR2-CCL2 axis in triple-negative breast cancer
    Authors: Magdalena Budzyń, Agata Kubicka, Elżbieta Kaja, Witold Kycler, Joanna Załuska-Kusz, Jacek J. Brzeziński, Marcelina Sperling, Alicja Bukowska, Joanna Grupińska
    Year: 2025

 

  • Nutritional Behaviors, Vitamin Supplementation and Physical Activity among Polish Adults during the COVID-19 Pandemic
    Authors: Bogna Gryszczyńska, Magdalena Budzyń, Joanna Grupińska, Magdalena Paulina Kasprzak, Agnieszka Gryszczyńska
    Year: 2022

 

  • Beneficial Effects of Oral Nutritional Supplements on Body Composition and Biochemical Parameters in Women with Breast Cancer Undergoing Postoperative Chemotherapy: A Propensity Score Matching Analysis
    Authors: Joanna Grupińska, Magdalena Budzyń, Kalina Maćkowiak, Jacek Jakub Brzeziński, Witold Kycler, Ewa Leporowska, Bogna Gryszczyńska, Magdalena Paulina Kasprzak, Maria Iskra, Dorota Formanowicz
    Year: 2021

 

  • Association between clinicopathological features of breast cancer with adipocytokine levels and oxidative stress markers before and after chemotherapy
    Authors: Magdalena Budzyń
    Year: 2021

 

  • Changes in the Nrf2/Keap1 Ratio and PON1 Concentration in Plasma of Patients Undergoing the Left Main Coronary Artery Stenting
    Authors: Magdalena Budzyń
    Year: 2020

 

  • Selected Atherosclerosis-Related Diseases May Differentially Affect the Relationship between Plasma Advanced Glycation End Products, Receptor sRAGE, and Uric Acid
    Authors: Bogna Gryszczyńska, Magdalena Budzyń, Dorota Formanowicz, Maria Wanic-Kossowska, Piotr Formanowicz, Wacław Majewski, Maria Iskra, Magdalena P. Kasprzak
    Year: 2020

 

  • Association between Advanced Glycation End Products, Soluble RAGE Receptor, and Endothelium Dysfunction, Evaluated by Circulating Endothelial Cells and Endothelial Progenitor Cells in Patients with Mild and Resistant Hypertension
    Authors: Magdalena Budzyń
    Year: 2019

 

  • The Potential Role of Circulating Endothelial Cells and Endothelial Progenitor Cells in the Prediction of Left Ventricular Hypertrophy in Hypertensive Patients
    Authors: Magdalena Budzyń
    Year: 2019

 

  • Advanced Oxidation Protein Products and Carbonylated Proteins Levels in Endovascular and Open Repair of an Abdominal Aortic Aneurysm: The Effect of Pre-, Intra-, and Postoperative Treatment
    Authors: Bogna Gryszczyńska, Magdalena Budzyń, Dorota Formanowicz, Piotr Formanowicz, Zbigniew Krasiński, Natalia Majewska, Maria Iskra, Magdalena P. Kasprzak
    Year: 2019

 

Conclusion

Dr. Budzyń’s contributions to medical sciences extend beyond academia, influencing the fields of laboratory diagnostics and cardiovascular research. Her work has significantly improved the understanding of endothelial dysfunction and biomarker-based diagnostics, paving the way for better clinical applications. With her ongoing dedication to research and education, she continues to inspire the next generation of scientists while striving to make impactful advancements in medical science.

Baoying Huang | Pathogen Biology | Best Researcher Award

Baoying Huang | Pathogen Biology | Best Researcher Award

Ms. Baoying Huang,  National Institute for Viral Disease Control and Prevention, China.

Dr. Baoying Huang, a distinguished professor at the Biotech Center for Viral Disease Emergency, China CDC, has over two decades of experience in combating viral diseases. Her expertise lies in vaccine and antiviral drug development for emerging and re-emerging infectious diseases, including COVID-19, monkeypox, and other human coronaviruses.

 

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🎓 Education Experience

2008.09–2011.07: Doctor of Medicine, Pathogen Biology,Biotech Center for Viral Disease Emergency, China CDC.2005.09–2008.07: Master of Biology, Pathogen Biology,Biotech Center for Viral Disease Emergency, China CDC. 2001.09–2005.07: Bachelor of Biology,
Life Science Department, Nan Hua University, China.

👩‍🔬 Professional Experience

2020.07–Present:  Professor, China CD ,Focus: Vaccine and antiviral drug R&D for SARS-CoV-2 and poxvirus diseases, including COVID-19 and monkeypox. Key Role: Participated in COVID-19 Emergency Projects for SARS-CoV-2 variant monitoring in China.2015.07–2020.07:  Associate Professor, China CDC. Focus: Vaccine and antiviral drug R&D for emerging infectious diseases like influenza and coronaviruses (SARS-CoV, MERS-CoV).2015.04–2015.06:  Assistant Professor, China CDC. Global Health Support Program: Worked in Sierra Leone to establish Ebola lab systems, improving public health infrastructure.2011.07–2015.07: Assistant Professor, China CDC. Focus: Pathogenic molecular mechanisms of influenza viruses, pseudo-virus applications, and gene-engineered vaccines. 2005.09–2011.07:  Graduate Researcher, IVDC, China CDC. Specialization: Developing universal influenza vaccines for cross-protection against various strains.

🔬 Research Focus

Baoying Huang’s work is dedicated to:Vaccine Development: COVID-19 vaccines (BBIBP-CorV, mRNA vaccines) and pan-orthopoxvirus solutions.Emerging Diseases: Countermeasures for SARS-CoV-2, monkeypox, and other viral threats.Diagnostics: Whole-genome sequencing and real-time PCR for virus detection and monitoring.Therapeutics: Screening novel antivirals targeting viruses like SARS-CoV-2 and monkeypox.Key achievements include:Leading the development of Sinopharm COVID-19 vaccine, later approved by WHO for Emergency Use Listing.Establishing monitoring systems for SARS-CoV-2 variants and assessing their impact on public health measures. Advancing monkeypox vaccine research and identifying promising antiviral compounds against orthopoxviruses.

📚 Publications

  • Title: Molecular architecture of monkeypox mature virus
    • Authors: Hong, Y., Huang, B., Zhang, J., Tan, W., Li, S.
    • Year: 2024

 

  • Title: Vaccinia virus Tiantan strain blocks host antiviral innate immunity and programmed cell death by disrupting gene expression
    • Authors: Wu, C., Zhang, Z., Li, Z., Deng, Y., Tan, W.
    • Year: 2024

 

  • Title: A clinically used anti-human papilloma virus agent (3-hydroxyphthalic anhydride-modified bovine β-lactoglobulin) has a potential for topical application to prevent sexual transmission of monkeypox virus
    • Authors: Sha, Y., Huang, B., Hua, C., Tan, W., Jiang, S.
    • Year: 2024

 

  • Title: Development of a multiplex real-time PCR assay for the simultaneous detection of mpox virus and orthopoxvirus infections
    • Authors: Fan, Z., Xie, Y., Huang, B., Tan, W., Guo, F.
    • Year: 2024

 

  • Title: Accurate determination of the whole genome sequencing and open reading frames composition of non-replicating Tiantan strain of vaccinia virus based on novel long read sequencing platform
    • Authors: Zhang, Z., Wu, C., Li, H., Huang, B., Tan, W.
    • Year: 2024

 

  • Title: Characterization of whole genomes from recently emerging Mpox cases in several regions of China, 2023
    • Authors: Wu, C., Cui, L., Pan, Y., Wang, Q., Tan, W.
    • Year: 2024

 

  • Title: Intranasal immunization with single-dose vaccine based on recombinant influenza virus H1N1 expressing the extracellular domain of respiratory syncytial virus G protein induces robust immunity and protection in mice
    • Authors: Han, R., Wang, D., Wang, T., Huang, B., Tan, W.
    • Year: 2024

 

  • Title: Rapid identification of full-length genome and tracing variations of monkeypox virus in clinical specimens based on mNGS and amplicon sequencing
    • Authors: Wu, C., A, R., Ye, S., Lu, J., Tan, W.
    • Year: 2024

 

  • Title: Long-lasting humoral and cellular memory immunity to vaccinia virus Tiantan provides pre-existing immunity against mpox virus in Chinese population
    • Authors: Li, M., Guo, Y., Deng, Y., Gao, G.F., Liu, J.
    • Year: 2024

 

  • Title: Identification of the VP37 pocket of monkeypox virus as a promising target for pan-orthopoxvirus inhibitors through virtual screening and antiviral assays
    • Authors: Huo, S., Wu, L., Huang, B., Xu, Z., Tan, W.
    • Year: 2024

 

Conclusion

Dr. Huang’s career exemplifies unwavering dedication to improving public health through innovation in vaccine development, antiviral research, and diagnostic technologies. Her contributions to tackling global health challenges, such as the COVID-19 pandemic and monkeypox outbreaks, have significantly impacted infectious disease prevention and control worldwide. As viruses continue to evolve, her pioneering work remains a cornerstone in safeguarding global health.