Dinh Phong Son | CircRNA | Best Researcher Award

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Dr. Dinh Phong Son | CircRNA | Best Researcher Award

Dr. DINH PHONG SON, DUYTAN UNIVERSITY, Vietnam.

Dr. Dinh Phong Son is a researcher specializing in laboratory medicine techniques with a Ph.D. in Molecular Medicine from Guangxi Medical University, China. His research focuses on modern molecular biology techniques, particularly the identification of potential biomarkers for early disease diagnosis and targeted therapy. His studies explore systemic diseases such as diabetes, cardiovascular diseases, and cancer, emphasizing gene editing technologies like CRISPR/Cas9. His recent publications contribute to the understanding of regulatory RNA networks and their implications in disease mechanisms, providing a foundation for future studies on molecular interactions and targeted drug development.

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🎓 Early Academic Pursuits

From the very beginning of my academic journey, I was deeply fascinated by the intricate mechanisms of life at a molecular level. My pursuit of knowledge led me to study Laboratory Medicine Technique at Hue University of Medicine and Pharmacy, Vietnam, where I honed my expertise in diagnostic methodologies and medical laboratory sciences. With an insatiable thirst for discovery, I furthered my education by earning a Doctorate (Ph.D.) in Molecular Medicine from Guangxi Medical University, China. This academic foundation set the stage for my dedication to the field of molecular biology, shaping my vision to explore genetic markers and innovative diagnostic tools.

👩‍🎓 Professional Endeavors

Currently, I serve at Duy Tan University, College of Medicine and Pharmacy, where I actively contribute to research, mentoring, and academic discourse. My work primarily revolves around molecular diagnostics, genetic analysis, and disease biomarker identification, aiming to bridge the gap between molecular biology and clinical applications. With advancements in next-generation sequencing (NGS) and bioinformatics databases, I continually seek new pathways to enhance the precision of disease detection and treatment strategies.

🧪 Contributions and Research Focus

My research is deeply rooted in molecular medicine, focusing on the identification of potential biomarkers for the early diagnosis of systemic diseases such as diabetes, cardiovascular diseases, stroke, and cancer. My investigations also extend to exploring gene targets for pharmacological studies, assisting in drug development through the modulation of gene expression using cutting-edge technologies like CRISPR/Cas9, gene overexpression, and silencing approaches. Furthermore, my work delves into the complex LncRNA/CircRNA/miRNA/gene/protein-drug interaction networks, paving the way for theoretical models that could revolutionize targeted therapy research.

 

💎 Impact and Influence

The impact of my research extends beyond academia, as it plays a crucial role in early disease screening, personalized medicine, and therapeutic advancements. By leveraging molecular networks, I aim to facilitate the development of precise diagnostic tools and gene-targeted interventions, significantly improving patient outcomes. My research findings have the potential to reshape biomedical applications and create avenues for innovative treatment strategies across various diseases.

🌟 Legacy and Future Contributions

Looking ahead, my aspirations remain steadfast in expanding molecular biology research, particularly in uncovering novel biomarkers and refining gene-editing techniques. As the field continues to evolve, I hope to contribute to the refinement of therapeutic gene modifications and biomarker-based diagnostics. With sustained efforts and collaborations, I envision a future where my research serves as a cornerstone for breakthroughs in precision medicine, targeted gene therapy, and advanced molecular diagnostics.

👨‍💼 Professional Collaborations and Memberships

As an active member of the scientific community, I engage in collaborations and professional affiliations to foster knowledge exchange and multidisciplinary research. My involvement in editorial appointments, consultancy projects, and industry partnerships enables me to extend my research impact, ensuring that molecular medicine continues to advance for the benefit of humanity.

 

Publication

  • Title: Identification and assessment of hub genes and miRNAs coregulatory associated with immune infiltrations and drug interactions in latent tuberculosis based on Microarray Data analysis, molecular docking, and dynamic simulation
    Authors: PhongSon Dinh, ChauMyThanh Tran, ThiPhuongHoai Dinh, Hai-Anh Ha, Aigul Utegenova, Awais Ali, Abdulaziz Alamri
    Year: 2025

 

  • Title: Hsa_circRNA_0000284 acts as a ceRNA to participate in coronary heart disease progression by sponging miRNA-338-3p via regulating the expression of ETS1
    Authors: PhongSon Dinh, ChauMyThanh Tran, ThiPhuongHoai Dinh, Awais Ali, ShangLing Pan
    Year: 2024

 

  • Title: Potential diagnostic value of serum microRNAs for 19 cancer types: a meta-analysis of bioinformatics data
    Authors: ChauMyThanh Tran, PhongSon Dinh
    Year: 2024

 

  • Title: Identification of hsa_circ_0001445 of a novel circRNA-miRNA-mRNA regulatory network as potential biomarker for coronary heart disease
    Authors: PhongSon Dinh, JunHua Peng, ThanhLoan Tran, DongFeng Wu, ChauMyThanh Tran, ThiPhuongHoai Dinh, ShangLing Pan
    Year: 2023

 

  • Title: Construction of miRNAs and gene expression profiles associated with ischemic cardiomyopathy: Bioinformatics analysis
    Authors: PhongSon Dinh, Jun-Hua Peng, ChauMyThanh Tran, ThanhLoan Tran, Shang-Ling Pan
    Year: 2022

 

Conclusion

Dr. Son’s research plays a crucial role in advancing molecular biology by identifying key biomarkers and regulatory networks for disease screening and treatment. His work in gene-targeted therapy and RNA interaction networks lays the groundwork for future innovations in precision medicine. Despite challenges in resources and time, his commitment to molecular research aims to drive further advancements in understanding and treating complex diseases.

John Vincent Sanchez Orti | Biomarkers in Neurocognition | Young Scientist Award

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Dr. John Vincent Sanchez Orti | Biomarkers in Neurocognition | Young Scientist Award

Dr. Joan Vicent Sánchez Ortí, Health research institute,  Spain.

Joan Vicent Sánchez Ortí is a Clinical Psychologist and Neuropsychologist currently working as a Research Technician at the Instituto de Investigación Sanitaria – INCLIVA. He is also a predoctoral researcher affiliated with CIBERSAM (Group 24, Universitat de València). His academic background includes a Bachelor’s degree in Psychology (2016), a Master’s in General Health Psychology (2019), and a Master’s in Basic and Applied Neurosciences (2021), all from Universitat de València. He is currently pursuing a Ph.D. in Medicine.

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🧠 A Passion for Understanding the Mind

Joan Vicent Sánchez Ortí was born on August 6, 1994, with an innate curiosity about the complexities of human cognition. From an early age, he displayed a deep interest in psychology and neuroscience, which led him to pursue an academic path dedicated to unraveling the mysteries of the brain. His journey began at the Universitat de València, where he obtained his degree in Psychology in 2016. Motivated by his growing fascination with neuropsychology, he continued his studies, earning a Master’s in General Health Psychology in 2019 and a Master’s in Basic and Applied Neurosciences in 2021. His dedication to advancing medical science led him to enroll in an official Doctorate Program in Medicine at the same institution.

🏥 Bridging Psychology and Neuroscience in Professional Practice

Currently serving as a Neuropsychologist and Research Technician at the Health Research Institute (INCLIVA) in Spain, Joan Vicent plays a vital role in understanding cognitive impairments associated with severe mental disorders. His affiliation with the Biomedical Research Center in Mental Health Network (CIBERSAM) – Group 24 at the Universitat de València has allowed him to contribute significantly to groundbreaking studies. His expertise lies in assessing neurocognitive deficits, biomarkers, and epigenetic factors, aiming to enhance the diagnosis and treatment of psychiatric and neurological conditions.

🔬 Advancing Research in Neurocognitive Deficits and Mental Health

Joan Vicent’s research delves into the intricate connections between brain function, cognition, and mental health. His studies focus on identifying early biomarkers of cognitive decline, exploring epigenetic influences, and evaluating social functioning and quality of life in patients suffering from severe mental disorders. His contributions have been instrumental in improving the understanding of conditions such as schizophrenia, bipolar disorder, and neurodegenerative diseases, providing valuable insights for clinical interventions.

🏆 Recognized for Excellence in Neuroscience and Psychology

Through his commitment to scientific discovery, Joan Vicent has garnered recognition in the field of neuroscience and psychology. His contributions to neuropsychology and mental health research have positioned him as a promising figure in cognitive science. His work is widely acknowledged for its impact on the development of new therapeutic approaches and diagnostic techniques. With a strong academic and research background, he continues to be an influential voice in the study of cognitive impairment.

🌍 Impacting Lives Through Mental Health Research

Beyond academic achievements, Joan Vicent’s work has real-world implications, improving the quality of life for individuals facing cognitive challenges. His research contributes to developing more effective treatments, enhancing diagnostic accuracy, and fostering a better understanding of mental disorders. Through his role at INCLIVA and CIBERSAM, he actively collaborates with interdisciplinary teams, ensuring that his findings are translated into clinical practice, ultimately benefiting patients and healthcare professionals alike.

🚀 Paving the Way for Future Innovations in Neuropsychology

With a strong foundation in psychology, neuroscience, and medicine, Joan Vicent remains dedicated to pushing the boundaries of cognitive research. His ongoing studies aim to integrate cutting-edge techniques in neuroimaging, genetics, and artificial intelligence to refine the understanding of neurocognitive disorders. His ambition is to contribute to the development of personalized medicine, where treatments are tailored to an individual’s neurobiological and psychological profile, revolutionizing mental healthcare.

🔮 A Vision for a Healthier, Cognitively Resilient Future

Looking ahead, Joan Vicent Sánchez Ortí envisions a world where mental health is better understood, diagnosed, and treated with precision. His dedication to neuropsychology and cognitive research will continue to shape the future of mental healthcare, inspiring new generations of scientists and clinicians. As he advances in his career, his unwavering commitment to improving lives through research stands as a testament to his passion and perseverance in the field of neuroscience.

Publication

  • Manual motor speed dysfunction as a neurocognitive endophenotype in euthymic bipolar disorder patients and their healthy relatives. Evidence from a 5-year follow-up study
    P Correa-Ghisays, V Balanzá-Martínez, G Selva-Vera, J Vila-Francés, …
    2017

 

  • Grip Strength, Neurocognition, and social functioning in people With Type-2 diabetes mellitus, major depressive disorder, bipolar disorder, and schizophrenia
    M Aliño-Dies, JV Sanchez-Orti, P Correa-Ghisays, V Balanzá-Martinez, …
    2020

 

  • Visual memory dysfunction as a neurocognitive endophenotype in bipolar disorder patients and their unaffected relatives. Evidence from a 5-year follow-up Valencia study
    P Correa-Ghisays, JV Sánchez-Ortí, R Ayesa-Arriola, E Setién-Suero, …
    2019

 

  • Specific metabolic syndrome components predict cognition and social functioning in people with type 2 diabetes mellitus and severe mental disorders
    JV Sanchez‐Orti, V Balanzá‐Martinez, P Correa‐Ghisays, G Selva‐Vera, …
    2022

 

  • Immune–Inflammatory Biomarkers Predict Cognition and Social Functioning in Patients With Type 2 Diabetes Mellitus, Major Depressive Disorder, Bipolar Disorder, and …
    M Garés-Caballer, JV Sánchez-Ortí, P Correa-Ghisays, …
    2022

 

  • Probiotic, prebiotic, synbiotic and fermented food supplementation in psychiatric disorders: A systematic review of clinical trials
    C Ribera, JV Sánchez-Ortí, G Clarke, W Marx, S Mörkl, …
    2024

 

  • Transdiagnostic neurocognitive deficits in patients with type 2 diabetes mellitus, major depressive disorder, bipolar disorder, and schizophrenia: A 1-year follow-up study
    P Correa-Ghisays, JV Sanchez-Orti, V Balanza-Martinez, G Selva-Vera, …
    2022

 

  • Inflammation and lipid metabolism as potential biomarkers of memory impairment across type 2 diabetes mellitus and severe mental disorders
    JV Sanchez-Orti, P Correa-Ghisays, V Balanza-Martinez, G Selva-Vera, …
    2023

 

  • MICEmi: A method to identify cognitive endophenotypes of mental illnesses
    P Correa-Ghisays, JV Sanchez-Orti, V Balanza-Martinez, I Fuentes-Dura, …
    2022

 

  • Specific immune-inflammatory profiles and neurocognitive deficits predict illness trajectories in people with type 2 diabetes mellitus or psychiatric disorders
    JV Sanchez-Orti, P Correa-Ghisays, V Balanza-Martinez, G Selva-Vera, …
    2025

 

Conclusion 🎯

Joan Vicent Sánchez Ortí’s dedication to neuroscience and mental health research positions him as an influential figure in the field. His expertise bridges psychology, medicine, and genetics, offering innovative solutions for cognitive disorders. With a strong commitment to improving lives through research, his work has already made a meaningful impact and will continue to shape the future of mental healthcare, neuropsychology, and personalized medicine. As he advances in his career, his passion and contributions will undoubtedly lead to groundbreaking discoveries in cognitive science.

Kawthar Diab | Life Science | Best Researcher Award

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Kawthar Diab | Life Science | Best Researcher Award

Prof. Dr. Kawthar Diab, National Research Centre, Egypt.

Dr. Kawthar Abdelaziz Elsayed Mohamed Diab is a distinguished Research Professor in Genetics and Cytology at the National Research Centre, Cairo, Egypt. With a strong foundation in zoology, she pursued advanced degrees focusing on genotoxicity, cytogenetics, and medicinal plant applications in disease prevention. Her postdoctoral research at Tokai University, Japan, and the Indian Institute of Integrative Medicine, India, expanded her expertise in cancer pharmacology and bioscience. Dr. Diab has made significant contributions to genetic toxicology and the chemopreventive properties of medicinal plants, with a particular focus on the Lamiaceae family and Himalayan plants. She actively mentors Ph.D. students and collaborates on groundbreaking research projects, gaining international recognition through conferences and workshops.

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🌱 Early Academic Pursuits

Kawthar Abdelaziz Elsayed Mohamed Diab embarked on her academic journey with a deep passion for zoology, earning her B.Sc. in Zoology from Al-Azhar University in 1996 with a distinguished grade of “Very Good.” She further honed her expertise by obtaining an M.Sc. in Experimental Zoology from Zagazig University in 2003, where she conducted cytogenetic and immunogenetic studies on the effects of chemotherapy drugs on reproduction. Her academic curiosity and dedication led her to pursue a Ph.D. in Zoology at Ain Shams University, awarded in 2009. Her doctoral research focused on the protective effects of medicinal plants against genotoxic damage induced by hydrocortisone in mice, marking the beginning of her lifelong commitment to genetic research and cytology.

🧬 Professional Endeavors

As a Research Professor at the Genetics and Cytology Department of the National Research Centre in Cairo, Egypt, Dr. Kawthar Diab has played a pivotal role in advancing genetic studies. Her postdoctoral fellowships further expanded her scientific horizons—first in Cancer Pharmacology at the Indian Institute of Integrative Medicine in 2012 and later in Bioscience at Tokai University, Japan, in 2014. These international research experiences enriched her expertise in genetic applications, cytogenetics, and pharmacogenomics. Her relentless pursuit of knowledge has positioned her as a leading researcher in genetic and cytological studies, bridging traditional knowledge with cutting-edge scientific advancements.

🌿 Contributions and Research Focus

Dr. Diab’s research delves into the genotoxicity of pharmaceutical compounds and the protective effects of medicinal plants. Her investigations focus on the genetic impact of chemotherapy drugs and natural therapeutic agents, particularly those derived from the Lamiaceae family, known for their biochemical and therapeutic properties. Her recent supervision of Ph.D. research on biochemical and therapeutic evaluations of medicinal plants for prostate diseases underscores her commitment to integrating molecular genetics with natural medicine. Additionally, her work on cancer chemoprevention using Himalayan plants has gained international recognition, reflecting her dedication to discovering novel plant-based remedies for serious health conditions.

🌍 Accolades and Recognition

Dr. Kawthar Diab’s expertise has been acknowledged on the global stage. She was invited as a speaker at the 6th Rajabhat University National and International Research and Academic Conference (2020), where she presented her groundbreaking research on cancer chemopreventive activity of Himalayan plants. She has also participated in esteemed international workshops, including the Fluorescence Microscopy Workshop at ICGEB, New Delhi (2019), further enhancing her methodological skills. These recognitions highlight her contributions to genetic research and her growing influence in the scientific community.

📖 Impact and Influence

Beyond her research, Dr. Diab is actively shaping the next generation of scientists. She mentors young researchers, including Ph.D. students working on innovative projects in pharmacogenomics and plant-based medicine. Her collaboration with interdisciplinary teams ensures that her work extends beyond academic publications, making real-world contributions to medical science and genetics. By fostering a culture of inquiry and scientific exploration, she continues to inspire budding researchers to explore the genetic foundations of disease prevention and treatment.

🔬 Legacy and Future Contributions

With a research portfolio spanning genetic toxicology, medicinal plant applications, and cytogenetics, Dr. Kawthar Diab’s legacy is firmly established in the scientific world. She envisions a future where genetic research and plant-based therapeutics converge to provide safer, more effective treatments for cancer and genetic disorders. Her continuous engagement with international scientific platforms and her mentorship of emerging scholars ensure that her influence will extend far beyond her own research, shaping the future of genetic and cytological studies.

Publication

  • Title: In Vitro Anticancer Activities of Anogeissus latifolia, Terminalia bellerica, Acacia catechu and Moringa oleifera Indian Plants
    Author: KAE Diab, SK Guru, S Bhushan, AK Saxena
    Year: 2015

 

  • Title: In vitro studies on phytochemical content, antioxidant, anticancer, immunomodulatory, and antigenotoxic activities of lemon, grapefruit, and mandarin citrus peels
    Author: KAE Diab
    Year: 2016

 

  • Title: In vivo comparative studies on antigenotoxicity of date palm (Phoenix dactylifera L.) pits extract against DNA damage induced by N-Nitroso-N-methylurea in mice
    Author: KA Diab, EI Aboul-Ela
    Year: 2012

 

  • Title: Carbon tetrachloride induced hepato/renal toxicity in experimental mice: antioxidant potential of Egyptian Salvia officinalis L essential oil
    Author: MA Fahmy, KA Diab, NS Abdel-Samie, EA Omara, ZM Hassan
    Year: 2018

 

  • Title: Genotoxicity of carbon tetrachloride and the protective role of essential oil of Salvia officinalis L. in mice using chromosomal aberration, micronuclei formation, and …
    Author: KAE Diab, MA Fahmy, ZM Hassan, EM Hassan, AB Salama, EA Omara
    Year: 2018

 

  • Title: Inhibitory activity of black mulberry (Morus nigra) extract against testicular, liver and kidney toxicity induced by paracetamol in mice
    Author: KA Diab, MA Fahmy, EM Hassan, ZM Hassan, EA Omara, …
    Year: 2020

 

  • Title: The impact of the low frequency of the electromagnetic field on human
    Author: KA Diab
    Year: 2020

 

  • Title: Inhibitory activity of flaxseed oil against CdCl2 induced liver and kidney damage: Histopathology, genotoxicity, and gene expression study
    Author: KA Diab, NE Ibrahim, MA Fahmy, EM Hassan, EA Omara
    Year: 2020

🏆 Conclusion

Dr. Kawthar Diab’s journey from an aspiring zoologist to a distinguished Research Professor in Genetics and Cytology is a testament to her unwavering commitment to scientific discovery. Her work not only enhances our understanding of genetic toxicology but also paves the way for integrating traditional medicinal knowledge with modern genetic research. As she continues to push the boundaries of genetic science, her contributions remain invaluable to both academia and global health advancements.

Bastian Höchst | Onco- Immunology | Best Researcher Award

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Dr. Bastian Höchst | Onco- Immunology | Best Researcher Award

Dr. Bastian Höchst,  Institute of Molecular Immunology, MRI, TUM, Germany.

Bastian Höchst is a distinguished molecular immunologist whose career spans groundbreaking research, impactful teaching, and valuable contributions to the scientific community. His academic journey began with a focus on biology and culminated in a doctorate on immune regulation in liver tumors. As a Research Group Leader at the Technical University of Munich, he investigates the complex interplay of immune cells and tissues in acute and chronic inflammation. His pioneering discoveries, such as the mechanisms governing myeloid suppressor cells and immune-regulatory metabolite transfer, have advanced understanding in the field.

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🌱 Early Academic Pursuits

Bastian Höchst began his academic journey with a passion for understanding the intricate mechanisms of biology. From 1999 to 2005, he pursued his studies in Biology at the University of Bonn and Hamburg, laying the foundation for his future endeavors in molecular immunology. His academic curiosity led him to pursue a doctorate at the Medical School Hannover under the guidance of Prof. Dr. Tim F. Greten. His doctoral research focused on identifying and characterizing myeloid-derived suppressor cells in patients with hepatocellular carcinoma, marking the beginning of his impactful contributions to the field of immunology.

🔬 Professional Endeavors

Currently serving as a Research Group Leader at the Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University of Munich (TUM), Bastian Höchst has dedicated his career to unraveling the complexities of immune regulation. His journey in academia has been marked by significant roles, including his previous tenure as a Research Group Leader at the Institute for Animal Physiology and Immunology, Wissenschaftszentrum Weihenstephan, TUM. Additionally, his postdoctoral fellowship at the Institute of Molecular Medicine and Experimental Immunology at the University of Bonn further honed his expertise in immune mechanisms.

🧪 Contributions and Research Focus

Bastian Höchst’s research delves into immune regulation within acute and chronic inflammatory processes, with a particular focus on tissue-specific mechanisms. He has made groundbreaking discoveries, including elucidating the pathways that govern the generation of myeloid suppressor cells in liver tumors. Furthermore, his innovative work revealed that the intercellular transfer of immune-regulatory metabolites is critical to T-cell effector functions. His research has significantly advanced the understanding of immune responses in disease contexts, bridging gaps in immunological knowledge.

🎓 Teaching and Mentorship

A dedicated educator, Bastian Höchst has been actively involved in teaching since 2010, inspiring students in life sciences programs at TUM. His lectures on topics such as onco-immunology, immune metabolism, and immunotherapy provide invaluable insights to aspiring scientists. Through lab courses on immune cell phenotyping and advanced techniques like spectral flow cytometry, he has empowered students with the skills to explore the complexities of immunology. His teaching contributions extend beyond knowledge dissemination, fostering a generation of critical thinkers and innovators.

📜 Accolades and Recognition

Bastian’s expertise has been recognized through his habilitation and venia legendi for Molecular Immunology, under the mentorship of Prof. Dr. Percy Knolle. His contributions as a scientific reviewer for prestigious journals like Hepatology, Journal of Hepatology, and Frontiers in Immunology further reflect his authority in the field. Additionally, his role in evaluating grant applications for the Deutsche Forschungsgemeinschaft (DFG) underscores his impact on shaping future research initiatives.

🌍 Impact and Influence

Through his research, teaching, and reviews, Bastian Höchst has left an indelible mark on the field of molecular immunology. His work not only uncovers critical mechanisms of immune regulation but also provides pathways for therapeutic advancements in inflammatory and tumor-related conditions. His contributions influence both scientific understanding and practical applications, addressing global challenges in health and disease management.

🌟 Legacy and Future Contributions

Bastian Höchst’s journey is one of passion, discovery, and impact. As he continues to lead groundbreaking research, he sets the stage for a future where immune-based therapies are revolutionized. His legacy lies in his ability to connect fundamental research with real-world applications, inspiring colleagues and mentees alike. With his unwavering commitment to scientific exploration, Bastian Höchst is poised to shape the future of molecular immunology, paving the way for transformative breakthroughs.

Publication

  • A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4+ CD25+ Foxp3+ T cells
    Authors: B. Höchst, L.A. Ormandy, M. Ballmaier, F. Lehner, C. Krüger, M.P. Manns, …
    Year: 2008

 

  • Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor
    Authors: B. Höchst, T. Voigtlaender, L. Ormandy, J. Gamrekelashvili, F. Zhao, …
    Year: 2009

 

  • Functional classification of memory CD8+ T cells by CX3CR1 expression
    Authors: J.P. Böttcher, M. Beyer, F. Meissner, Z. Abdullah, J. Sander, B. Höchst, …
    Year: 2015

 

  • Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells
    Authors: B. Höchst, J. Gamrekelashvili, M.P. Manns, T.F. Greten, F. Korangy
    Year: 2011

 

  • S100A9 a new marker for monocytic human myeloid‐derived suppressor cells
    Authors: F. Zhao, B. Höchst, A. Duffy, J. Gamrekelashvili, S. Fioravanti, M.P. Manns, …
    Year: 2012

 

  • Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal
    Authors: T. Baumann, A. Dunkel, C. Schmid, S. Schmitt, M. Hiltensperger, K. Lohr, …
    Year: 2020

 

  • Kupffer cell-derived Tnf triggers cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS
    Authors: D. Yuan, S. Huang, E. Berger, L. Liu, N. Gross, F. Heinzmann, M. Ringelhan, …
    Year: 2017

 

  • Low-dose cyclophosphamide treatment impairs regulatory T cells and unmasks AFP-specific CD4+ T-cell responses in patients with advanced HCC
    Authors: T.F. Greten, L.A. Ormandy, A. Fikuart, B. Höchst, S. Henschen, M. Hörning, …
    Year: 2010

 

Conclusion

Bastian Höchst’s career exemplifies dedication to advancing molecular immunology through innovative research, education, and mentorship. His contributions have shaped the understanding of immune responses in disease contexts, offering hope for novel therapeutic approaches. As he continues to lead impactful research and foster new talent, Bastian Höchst remains a visionary in his field, poised to drive future breakthroughs that bridge science and medicine for the benefit of society.

 

Liliane Massade | Targeted therapy | Innovation in Neuroscience Award

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Liliane Massade | Targeted therapy | Innovation in Neuroscience Award

Dr. Liliane Massade, INSERM, France.

Dr. Liliane Massade is a visionary research leader whose work integrates molecular biology, nanotechnology, and translational medicine. From her academic roots in Lebanon to her pioneering research in France, she has achieved significant milestones, including the development of siRNA-based therapies for Charcot-Marie-Tooth disease and innovations in neurodegenerative and cancer treatments. Her career spans decades of groundbreaking discoveries, interdisciplinary collaborations, and impactful mentorship. With over 78 publications, patents, and numerous awards, Dr. Massade’s contributions are both scientifically profound and globally influential.

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🌟 Early Academic Pursuits

Dr. Liliane Massade’s academic journey began with her passion for biology and education. After earning her Master’s in Biology from Lebanese University in 1982, she followed her calling as a teacher, obtaining a Teaching Diploma from Ecole Normale, Lebanon, in 1981. Her thirst for knowledge led her to Paris Diderot University, where she completed an Advanced Studies Diploma (DEA) in Population Genetics and Evolution in 1986. By 1990, she had earned her Ph.D. in Population Genetics and Evolution, marking the start of her illustrious career. In 1996, she achieved the Authorization to Supervise Research (HDR), solidifying her role as a mentor and leader in her field.

🔬 Professional Endeavors

Dr. Massade’s career has been a symphony of innovation, leadership, and groundbreaking research. Since 2020, she has led a cutting-edge team at U1195 INSERM, Bicêtre University Hospital, focusing on targeted therapies for chemotherapy-induced peripheral neuropathies. Prior to this, she helmed teams at UMR 8203 CNRS, Gustave Roussy Institute, where she advanced anti-cancer therapies and explored molecular targets in thyroid cancer. Her earlier work at INSERM and CNRS saw her delve into estradiol signaling in breast cancer and enzymes in drug metabolism, laying the foundation for her expertise in molecular biology and translational medicine.

💡 Contributions and Research Focus

Dr. Massade’s pioneering spirit has transformed the fields of neurodegenerative diseases and oncology. She is celebrated for her groundbreaking siRNA-based therapies targeting PMP22, which have opened new horizons for Charcot-Marie-Tooth disease treatment. Her innovations extend beyond therapy, as her patented methods in nucleic acid transfer highlight her interdisciplinary approach. With a focus on integrating biology, chemistry, and nanotechnology, she leads research that merges fundamental science with clinical application, offering hope for conditions like peripheral neuropathy and neurodegeneration.

🏆 Accolades and Recognition

Throughout her career, Dr. Massade has earned prestigious accolades, including the Outstanding Achievement Award at the World Congress on Advances in Oncology in 2013 and the JW Griffin Prize for Regeneration from the Peripheral Nerve Society in 2021. Her impact is further underscored by her extensive publication record, with 78 works, an H-index of 26, and over 49 invited talks at international conferences. These honors reflect her global influence and her ability to inspire the next generation of researchers.

🌍 Impact and Influence

Dr. Massade’s contributions extend beyond her lab, as she evaluates research programs for renowned organizations like the ERC, ANR, and ARC. As a member of international committees such as LaBEX NanoSaclay, she ensures the advancement of cutting-edge nanotechnology. Her mentorship has shaped the careers of 10 postdoctoral researchers, 11 Ph.D. candidates, and 31 Master’s students, demonstrating her commitment to nurturing scientific talent.

🔗 Legacy and Future Contributions

As the co-founder of MAAsiRNA, Dr. Massade exemplifies the translation of research into real-world impact. With €7 million raised to develop therapies targeting PMP22, her work bridges the gap between science and patient care. Her vision for the future includes continued exploration of siRNA therapies and the development of innovative approaches to neuroprotection and cancer treatment. Her legacy is one of scientific excellence, interdisciplinary collaboration, and unwavering dedication to improving lives through research.

📚Publications

  • GRT-X Stimulates Dorsal Root Ganglia Axonal Growth in Culture via TSPO and Kv7.2/3 Potassium Channel Activation
    Authors: Léa El Chemali, Suzan Boutary, Song Liu, Guo-Jun Liu, Ryan J. Middleton, Richard B. Banati, Gregor Bahrenberg, Rainer Rupprecht, Michael Schumacher, Liliane Massaad-Massade
    Year: 2024

 

  • Optimizing Structure and Activity of the Squalenoyl-siRNA Nanoparticles
    Author: Liliane Massaad-Massade
    Year: 2023

 

  • Mutation of Proteolipid Protein 1 Gene: From Severe Hypomyelinating Leukodystrophy to Inherited Spastic Paraplegia
    Authors: Guy Khalaf, Claudia Mattern, Mélina Begou, Odile Boespflug-Tanguy, Charbel Massaad, Liliane Massaad-Massade
    Year: 2022

 

  • The Mitochondrial Translocator Protein (TSPO): A Key Multifunctional Molecule in the Nervous System
    Authors: Léa El Chemali, Yvette Akwa, Liliane Massaad-Massade
    Year: 2022

 

  • Supramolecular Organization and Biological Interaction of Squalenoyl siRNA Nanoparticles
    Authors: Marie Caillaud, Frédéric Gobeaux, Miryana Hémadi, Suzan Boutary, Patrick Guenoun, Didier Desmaële, Patrick Couvreur, Frank Wien, Fabienne Testard, Liliane Massaad-Massade
    Year: 2021

 

  • Squalenoyl siRNA PMP22 Nanoparticles Are Effective in Treating Mouse Models of Charcot-Marie-Tooth Disease Type 1A
    Author: Liliane Massaad-Massade
    Year: 2021

 

  • Treating PMP22 Gene Duplication-Related Charcot-Marie-Tooth Disease: The Past, the Present, and the Future
    Author: Liliane Massaad-Massade
    Year: 2020

 

  • Small Interfering RNA From the Lab Discovery to Patients’ Recovery
    Authors: Marie Caillaud, Mévidette El Madani, Liliane Massaad-Massade
    Year: 2020

 

  • Newly Identified LMO3-BORCS5 Fusion Oncogene in Ewing Sarcoma at Relapse Is a Driver of Tumor Progression
    Author: Liliane Massaad-Massade
    Year: 2019

 

  • A Novel Therapeutic Approach to Colorectal Cancer in Diabetes: Role of Metformin and Rapamycin
    Author: Liliane Massaad-Massade
    Year: 2019

 

  • Discovery of New Fusion Transcripts in a Cohort of Pediatric Solid Cancers at Relapse and Relevance for Personalized Medicine
    Author: Liliane Massaad-Massade
    Year: 2019

 

🌟 Conclusion

Dr. Liliane Massade is a beacon of innovation and leadership in molecular biology and targeted therapies. From her academic beginnings in Lebanon to her groundbreaking contributions in France, she has forged a path of excellence that inspires scientists worldwide. With her unparalleled expertise and passion, she continues to redefine the possibilities of modern medicine, leaving an indelible mark on science and humanity.

Gustave Mabiama | Epidemiology | Neuroscience Academic Distinction Award

Posted on by Neuroscientists

Dr. Gustave Mabiama | Epidemiology | Neuroscience Academic Distinction Award

Dr. Gustave Mabiama, The University of Douala, Cameroon.

Dr. Mabiama Gustave is an accomplished Senior Lecturer-Researcher and Head of Division of University Cooperation at the University of Ebolowa, Cameroon. With dual Ph.D. qualifications in Physiology-Physiopathology and Human Nutrition, he has an extensive academic background, including a Bachelor’s, Postgraduate Diploma, and Master’s degree in applied biology and nutrition. Over a professional career spanning two decades, Dr. Mabiama has contributed significantly to nutrition research, elderly health, HIV/AIDS care, and university education. His expertise extends to clinical training and international collaborations, reflecting his commitment to advancing science and improving community well-being.

 

profile

Scholar

📜 Academic Background

Ph.D.Biology-Health (Physiology-Physiopathology) – University of Limoges, France.Health Sciences (Human Nutrition) – University of Douala, Cameroon. Additional Degrees:Bachelor’s Degree in Applied Biology – University of Ngaoundéré, Cameroon.Postgraduate Diploma in Human Biology – University of Ngaoundéré, Cameroon.Master’s Degree in Food Science and Nutrition – University of Ngaoundéré, Cameroon

🏫 Professional Experience

Current Role:Lecturer-Researcher (Assistant to Senior Lecturer), ENSET Douala (2010–Present).Past Roles:PMTCT, Paediatric HIV, and Nutrition Coordinator – ID-Moundou, Chad / ID-Paris-Poitiers, France (2008–2009)Life and Earth Sciences Teacher & Health Club Supervisor – Protestant College of Ngaoundéré (2000–2008).Instructor, Department of Biological Sciences – Faculty of Science, University of Ngaoundéré (1997–2006).

🛠 Further Training/Internships

2021, Limoges (LINUT): Identifying swallowing disorders. 2020, Limoges (LINUT): Undernutrition in the elderly. 2019, Faculty of Medicine, Limoges: Nutrition in specific conditions (pressure sores, heart failure, palliative care, cancer).2019, Limoges (LINUT): Physical activity recommendations for older adults.2019, University Hospital – Nutrition Unit (Limoges): Internship in Specialized Obesity Care.

🎓 University Courses Attended

2019, Yaoundé: Training Workshop on Scientific Advice for Governments (Nature and Technology Research Fund / INGSA). 2015, Distance Learning: Expertise in Gerontology (University of Montpellier & Pierre and Marie Curie University – Unfinished).2009, Cotonou, Benin: University Course on Food Composition and Biodiversity (BIOVERSITY/FAO). 2007, Abomey-Calavi, Benin: International Training in Nutrition and Food Science (FINSA/FSA/UAC). 2004, Marseille, France: Summer School for Young HIV/AIDS Researchers (AIDES)

📚 Publications

  • Title: Nutritional status and associated factors among community-dwelling elderly
    Authors: G Mabiama, D Adiogo, PM Preux, JC Desport, P Fayemendy, P Jésus
    Year: 2021

 

  • Title: Nutritional status, dementia, and mobility among nursing home’s residents: First exhaustive cross-sectional study in Limousin territory (France)
    Authors: P Fayemendy, G Mabiama, T Vernier, A Massoulard-Gainant, …
    Year: 2021

 

  • Title: Undernutrition, overweight and obesity among elderly living in communities in Africa: a systematic review
    Authors: G Mabiama, D Adiogo, T Millimono, P Fayemendy, T Vernier, …
    Year: 2021

 

  • Title: Undernutrition, overweight and obesity prevalences among community-dwelling elderly in Africa – a systematic review
    Authors: G Mabiama, T Millimono, D Adiogo, F Boumediene, PM Preux, …
    Year: 2022

 

  • Title: Nutritional status and associated factors among the elderly in Guinea: a first national cross-sectional study
    Authors: TM Millimono, A Camara, G Mabiama, M Daffé, F Boumédiène, PM Preux, …
    Year: 2023

 

  • Title: Dénutrition, surpoids et obésité chez les personnes âgées vivant dans des communautés en Afrique: une revue systématique
    Authors: G Mabiama, D Adiogo, T Millimono, F Boumédiène, PM Preux, …
    Year: 2022

 

  • Title: Depressive syndrome, cognitive impairment, and associated factors among community-dwelling aged persons in Cameroon
    Authors: G Mabiama, D Adiogo, PM Preux, JC Desport, P Fayemendy, P Jésus
    Year: 2024

 

  • Title: Undernutrition, socio-demographic characteristics and eating habits of the elderly
    Authors: TM Millimono, A Camara, G Mabiama, F Toure, S Sidibé, PM Preux, …
    Year: 2024

 

  • Title: Analysis of the Feeding Habits and Nutritional Status of Adolescents in Private Non-boarding Secondary Schools in Bamenda II Municipality, Cameroon
    Authors: ENBP Ange, E Manga, G Mabiama, F Evariste
    Year: 2024

 

  • Title: Comparing health students’ attitudes towards dementia, epilepsy and psychiatric disorders: Knowledge, Attitudes and Practices study (KAP) in Low-and Middle-Income countries (LMIC)
    Authors: LC Piver, E Auditeau, M Vergonjeanne, B Calvet, E Ngoungou, …
    Year: 2024

 

Conclusion

Dr. Mabiama Gustave’s career exemplifies excellence in education, research, and public health initiatives. His significant contributions to human nutrition and elderly care are a testament to his dedication to improving lives through science. As a prominent academic and health professional, he continues to foster international partnerships and contribute meaningfully to advancing health sciences, particularly in Africa. His dynamic career serves as an inspiration for integrating research, teaching, and social impact.