Gulcin Gacar | Neurodegenerative Disease | Best Researcher Award

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Assoc. Prof. Dr. Gulcin Gacar | Neurodegenerative Disease | Best Researcher Award

Prof. Dr. Gulcin Gacar | Kocaeli University | Turkey

Associate Professor Dr. Gulcin Gacar of Kocaeli University is a distinguished researcher and educator in the fields of stem cell biology, regenerative medicine, and clinical microbiology. With over 200 scientific publications, including 54 in Web of Science and 37 in Scopus, she has garnered more than 900 citations and achieved an h-index of 17. Her groundbreaking research focuses on mesenchymal stem cells and exosomes, particularly their applications in neurodegenerative diseases like Alzheimer’s. She leads nationally funded projects and serves as a mentor to graduate students, contributing significantly to Turkey’s scientific advancement in cellular and molecular therapy.

Academic Profile

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Early Academic Pursuits

From the outset of her academic journey, Dr. Gülçin Gacar exhibited a strong dedication to medical sciences, particularly clinical microbiology and regenerative medicine. Her foundational studies laid the groundwork for her specialization in stem cell biology and advanced biomedical techniques. As she advanced through the academic ranks, her commitment to translational research became evident, inspiring a deep dive into the dynamic world of mesenchymal stem cells and cellular therapies.

Professional Endeavors

Currently serving as an Associate Professor at Kocaeli University, Dr. Gacar is affiliated with the Center for Stem Cell and Gene Therapies under the Institute of Health Sciences. She plays a critical role in bridging theoretical knowledge with clinical application. Her professional journey is characterized by a robust combination of teaching, research, and leadership, where she supervises graduate-level research and oversees important institutional initiatives in stem cell-based innovation.

Contributions and Research Focus

Dr. Gacar’s research primarily revolves around mesenchymal stem cells, exosomes (extracellular vesicles), and advanced applications of stem cell biology. One of her key projects involves investigating the therapeutic potential of exosomes derived from adipose tissue-origin mesenchymal stem cells on Alzheimer’s disease models using human neuroblastoma SHSY5Y cells. This cutting-edge study, supported by national scientific funding, illustrates her focus on neurological disorders and cellular therapies. With over 200 academic publications, including 54 indexed in Web of Science and 37 in Scopus, her work has become a cornerstone in regenerative medicine and neurocellular research.

Accolades and Recognition

Dr. Gacar’s exceptional scholarship is reflected in her impressive citation record—garnering over 900 citations with an h-index of 16 on Web of Science and 17 on Scopus. These metrics not only underscore the academic relevance of her research but also highlight her influence in the global scientific community. Her contributions have positioned her as a key opinion leader and trusted consultant in TÜBİTAK-funded national projects, further validating her expertise and dedication to scientific excellence.

Impact and Influence

Beyond publications and projects, Dr. Gacar is actively involved in mentoring the next generation of scientists. She has supervised numerous graduate theses, fostering a research culture grounded in innovation, rigor, and ethical science. Her influence extends into policy-making and practical clinical research, making her a vital figure in the implementation of stem cell technologies in both experimental and therapeutic contexts.

Legacy and Future Contributions

Dr. Gacar continues to expand the frontiers of stem cell research and regenerative neuroscience. Her ongoing efforts in developing novel diagnostic and therapeutic modalities through cellular and molecular engineering are poised to transform clinical approaches to degenerative diseases. With each project and publication, she reinforces her commitment to scientific discovery and paves the way for future breakthroughs in biotechnology and personalized medicine.

Neuroscience and Regenerative Innovation

At the intersection of neuroscience and regenerative biology, Dr. Gacar’s work exemplifies the possibilities of interdisciplinary research. Her current focus on exosome-based therapies in neurodegenerative conditions represents a bold step into the future of non-invasive, cell-free therapeutics. As the landscape of neuroscience evolves, her pioneering work will undoubtedly contribute to novel clinical strategies and global scientific advancement.

Publication

Isolation and in vitro characterisation of dental pulp stem cells from natal teeth
E Karaöz, BN Doğan, A Aksoy, G Gacar, S Akyüz, S Ayhan, ZS Genç
2010

Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers
E Karaoz, A Aksoy, S Ayhan, AE Sarıboyacı, F Kaymaz, M Kasap
2009

Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum
K Schallmoser, E Rohde, A Reinisch, C Bartmann, D Thaler, C Drexler, …
2008

High prevalence of OXA-51-type class D β-lactamases among ceftazidime-resistant clinical isolates of Acinetobacter spp.: co-existence with OXA-58 in multiple …
H Vahaboglu, F Budak, M Kasap, G Gacar, S Torol, A Karadenizli, …
2006

Immunoregulatory effects of human dental pulp-derived stem cells on T cells: comparison of transwell co-culture and mixed lymphocyte reaction systems
PC Demircan, AE Sariboyaci, ZS Unal, G Gacar, C Subasi, E Karaoz
2011

Protective effects of resveratrol on aging-induced cognitive impairment in rats
SS Gocmez, N Gacar, T Utkan, G Gacar, PJ Scarpace, N Tumer
2016

The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets
AT Özdemir, RBÖ Özdemir, C Kırmaz, AE Sarıboyacı, ZSÜ Halbutoğlları, …
2016

PER-1 is still widespread in Turkish hospitals among Pseudomonas aeruginosa and Acinetobacter spp.
F Kolayli, G Gacar, A Karadenizli, A Sanic, H Vahaboglu, Study Group
2005

Phenotypic and proteomic characteristics of human dental pulp derived mesenchymal stem cells from a natal, an exfoliated deciduous, and an impacted third molar tooth
G Akpinar, M Kasap, A Aksoy, G Duruksu, G Gacar, E Karaoz
2014

The role of PIN1 on odontogenic and adipogenic differentiation in human dental pulp stem cells
YM Lee, SY Shin, SS Jue, IK Kwon, EH Cho, ES Cho, SH Park, EC Kim
2014

Conclusion 

Considering her scholarly output, impactful research on stem cell-based therapies, leadership in national research initiatives, and dedication to mentoring, Dr. Gulcin Gacar is highly deserving of the Best Researcher Award. Her innovative work in exosome-based treatment strategies for neurodegenerative diseases positions her as a leader in translational medical science. With continued emphasis on global engagement and high-impact dissemination, her research will not only advance scientific frontiers but also contribute meaningfully to patient care and public health. Thus, she stands as an exemplary model of academic excellence, innovation, and social relevance in biomedical sciences.

Hongrui Meng | Neurodegenerative disease | Excellence in Research Award

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Prof. Dr. Hongrui Meng | Neurodegenerative disease | Excellence in Research Award

Prof. Dr. Hongrui Meng,  Institute of Neuroscience, Soochow University, China.

Dr. Hongrui Meng is a highly accomplished neuroscientist whose academic path began with a Ph.D. in Behavioural Neuroscience from Hamamatsu University School of Medicine in Japan. He later conducted postdoctoral research in molecular neurobiology and human genetics at Juntendo University, Tokyo. Currently a professor at the Institute of Neuroscience, Soochow University, Dr. Meng leads a research team dedicated to uncovering the molecular and mitochondrial mechanisms underlying Parkinson’s disease and ALS. His work spans high-impact research projects funded by JSPS, NSFC, and other prestigious bodies. In addition to numerous scientific publications, he has contributed to diagnostic innovation through patented miRNA detection methods. His influence extends beyond academia through translational applications such as wearable technologies for Parkinson’s symptom monitoring.

Profile

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🎓 Early Academic Pursuits

Dr. Hongrui Meng began his distinguished academic journey in the field of neuroscience by earning his Ph.D. in Behavioural Neuroscience from the prestigious Hamamatsu University School of Medicine in Japan. His early education and training laid a strong foundation in experimental neuroscience, with a focus on the behavioral manifestations of neurodegenerative conditions. These formative years not only sharpened his scientific curiosity but also equipped him with the cross-disciplinary expertise to address complex neurological questions.

🧠 Professional Endeavors

Following his doctoral studies, Dr. Meng advanced his specialization through postdoctoral training in molecular neurobiology and human genetics at Juntendo University in Tokyo. There, he immersed himself in high-level research focusing on the genetic underpinnings of neurological disorders. His competence and dedication soon earned him a faculty appointment as an Assistant Professor in the Department of Research for Neurodegenerative Diseases and Dementia. His professional arc reached a significant milestone in 2020 when he was promoted to Full Professor and moved to the Institute of Neuroscience at Soochow University, where he now leads the Laboratory of Molecular Neurology.

🧬 Contributions and Research Focus

Dr. Meng’s scientific contributions center on the molecular mechanisms of Parkinson’s disease and amyotrophic lateral sclerosis (ALS). His research bridges mitochondrial dysfunction, alpha-synuclein aggregation, and neurodegeneration. He has completed pivotal studies supported by the Japan Society for the Promotion of Science and the Takeda Pharmaceutical Foundation, delving into the role of CHCHD2 gene mutations and mitochondrial pathways. His ongoing projects funded by the National Natural Science Foundation of China (NSFC) explore mitochondrial unfolded protein responses (mtUPR), while another innovative project in Suzhou focuses on wearable technology for monitoring Parkinson’s disease symptoms—demonstrating his commitment to translational and patient-centered neuroscience.

🔬 Innovation and Scientific Output

A notable innovator, Dr. Meng has made strides in molecular diagnostic technologies. His work has led to the development of high-throughput RT-qPCR-based methods for detecting primary and precursor miRNAs, contributing to enhanced genetic analysis of neurodegenerative disorders. He holds a patent granted in South Africa and another under process in China, underscoring his role at the intersection of research and technology. Furthermore, his publications in highly regarded journals like Current Issues in Molecular Biology and Cell Communication and Signaling reflect a consistent record of impactful findings that inform both fundamental neuroscience and clinical approaches.

🏅 Accolades and Recognition

Dr. Meng’s ascent in the academic community has been marked by numerous grants, including multiple from the JSPS and NSFC, attesting to the trust placed in his research vision by top funding bodies. While a formal list of awards may be under-documented, his rapid progression from postdoctoral fellow to professor and research team leader in less than a decade speaks volumes about his recognition among peers and institutional leadership. His leadership in multi-disciplinary and international collaborations is an implicit accolade of his scientific reliability and visionary perspective.

🌍 Impact and Influence

Through his groundbreaking work on mitochondrial mechanisms and neurodegeneration, Dr. Meng is helping to reshape current understanding of Parkinson’s disease pathophysiology. His investigations into alpha-synucleinopathy and microglial disruption have provided fresh insights into cellular degeneration and neuroimmune interactions. Beyond academia, his involvement in developing wearable diagnostic tools highlights his drive to impact patient lives directly. As a consultant on neuroprotective treatments such as PD-018/19, he bridges the academic and pharmaceutical worlds to accelerate therapeutic discovery.

🔮 Legacy and Future Contributions

Looking forward, Dr. Meng is poised to be a leading figure in neurogenetic diagnostics and therapeutic innovation. His laboratory at Soochow University serves as an incubator for future discoveries in neurodegenerative disease mechanisms, and his continued work in mitochondrial research promises to inform emerging therapies. With a growing publication record, international patents, and a robust research pipeline, Dr. Meng’s legacy will be one of bridging basic neuroscience with clinical application—paving the way for novel interventions and a better understanding of brain disorders in the molecular era.

Publication

 

  • Title: Dicer Is Involved in Cytotoxicity and Motor Impairment Induced by TBPH Deficiency
    Authors: Xiang Long, Yijie Wang, Hongrui Meng
    Year: 2025

 

  • Title: Transcriptomic analysis of lipid metabolism genes in Alzheimer’s disease: highlighting pathological outcomes and compartmentalized immune status
    Authors: Sun Y., Zhang Y., Jiang M., Long X., Miao Y., Du H., Zhang T., Meng H., Ma X.
    Year: 2024

 

  • Title: CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis
    Authors: Aya Ikeda, Hongrui Meng, Daisuke Taniguchi, Muneyo Mio, Manabu Funayama, Kenya Nishioka, Mari Yoshida, Yuanzhe Li, Hiroyo Yoshino, Tsuyoshi Inoshita et al.
    Year: 2024

 

  • Title: TDP-43 mutations-induced defects in miRNA biogenesis and cytotoxicity by differentially obstructing Dicer activity in Drosophila and in vitro
    Authors: Xiang Long, Mengni Jiang, Yongzhen Miao, Huanhuan Du, Ting Zhang, Zhuoya Ma, Jiao Li, Chunfeng Liu, Hongrui Meng
    Year: 2024

 

  • Title: A Simple Technique to Assay Locomotor Activity in Drosophila
    Authors: Long X., Du H., Jiang M., Meng H.
    Year: 2023

 

  • Title: Functional MHCI deficiency induces ADHD-like symptoms with increased dopamine D1 receptor expression
    Authors: Meng H.-R., Suenaga T., Edamura M., Nakahara D., Murakami G., Fukuda A., Ishida Y.
    Year: 2021

 

  • Title: Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease
    Authors: Imai Y., Hattori N., Inoshita T., Shiba-Fukushima K., Meng H., Hara K.Y., Sawamura N.
    Year: 2019

 

  • Title: Mutations in CHCHD2 cause α-synuclein aggregation
    Authors: Ikeda A., Nishioka K., Takanashi M., Li Y., Mori A., Okuzumi A., Izawa N., Ishikawa K.-I., Funayama M., Imai Y. et al.
    Year: 2019

 

  • Title: Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling
    Authors: Mori A., Hatano T., Koinuma T., Kubo S.-I., Spratt S., Yamashita C., Okuzumi A., Imai Y., Hattori N., Inoshita T. et al.
    Year: 2019

 

  • Title: Twin CHCH proteins, CHCHD2, and CHCHD10: Key molecules of Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementia
    Authors: Imai Y., Hattori N., Meng H., Shiba-Fukushima K.
    Year: 2019

 

🧾 Conclusion

Dr. Hongrui Meng’s career reflects a dynamic blend of academic excellence, molecular research innovation, and translational neuroscience. His scientific endeavors have not only enriched the understanding of neurodegenerative diseases but have also paved the way for novel diagnostic and therapeutic strategies. With a growing portfolio of impactful research, patents, and leadership in neurobiology, Dr. Meng stands out as a driving force in the global fight against neurological disorders. His work promises continued contributions to neuroscience with lasting influence on both scientific knowledge and patient care.

 

Koagne Longpa Tamo Silas | Neuroinformatics | Pioneer Researcher Award

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Mr. Koagne Longpa Tamo Silas | Neuroinformatics | Pioneer Researcher Award

Mr.  Koagne Longpa Tamo Silas, University of Dschang, Cameroon.

Koagne Longpa Tamo Silas is a dedicated researcher in the field of medical physics, specializing in automation, artificial intelligence, and electronic system design. His academic journey from Bamenda State University to Dschang State University reflects his continuous pursuit of knowledge and innovation. His contributions to circuit simulation, embedded systems, and artificial neural networks have established him as a promising figure in medical physics.

Profile

Google Scholar

🎓 Early Academic Pursuits

Born on July 12, 1998, in Mbouda, Cameroon, Koagne Longpa Tamo Silas displayed a keen interest in science and technology from a young age. His passion for physics and engineering led him to pursue higher education at Bamenda State University, where he embarked on an academic journey in Electrical and Power Engineering. His undergraduate studies, from November 2015 to August 2018, laid the foundation for his expertise in electrical systems, automation, and circuit design. Eager to expand his knowledge, he continued his postgraduate studies in the same field at Bamenda State University from September 2018 to July 2020, honing his skills in power engineering and applied electronics.

🚀 Professional Endeavors

Determined to deepen his expertise, Koagne Longpa Tamo Silas transitioned into the field of physics, enrolling as a Ph.D. student at Dschang State University in December 2022. His academic pursuits in the Department of Physics align with his interests in medical physics, where he integrates automation, applied computer science, and electronics to innovate in the field. As a dedicated researcher, he continues to engage with the Faculty of Science at Dschang State University, contributing to the academic and scientific community with his research in medical physics and embedded systems.

🤖 Contributions and Research Focus

Koagne Longpa Tamo Silas has dedicated his research efforts to the intersection of medical physics, automation, and artificial intelligence. His work encompasses Analog Artificial Neural Networks, Embedded Systems, Circuit Simulation, Digital and Analog Electronics, and Microcontroller Programming. His proficiency in tools like Spice Simulation, Cadence Virtuoso, and Electronic Design Automation allows him to design and optimize medical devices and automated systems. His research aims to enhance diagnostic and therapeutic tools in medical physics by leveraging artificial intelligence and embedded systems.

🏆 Accolades and Recognition

Throughout his academic and research career, Koagne Longpa Tamo Silas has garnered recognition for his contributions to medical physics and electronics. His innovative approach to circuit simulation and signal processing has positioned him as a promising researcher in his field. His dedication to advancing medical technologies has earned him the respect of his peers and mentors, as he continues to contribute valuable insights to the scientific community.

🌐 Impact and Influence

Through his academic journey and research, Koagne Longpa Tamo Silas has influenced the way automation and artificial intelligence are integrated into medical physics. His work in digital electronics and microcontroller programming is paving the way for innovative solutions in the medical field. His contributions extend beyond research, as he actively engages with students and researchers, fostering a culture of knowledge-sharing and scientific exploration.

 

Publication

  • A High-Resolution Non-Volatile Floating Gate Transistor Memory Cell for On-Chip Learning in Analog Artificial Neural Networks
    Authors: KLT Silas, DTA Bernard, FT Bernard, L Jean-Pierre, GW Ejuh
    Year: 2025

 

  • Breast Cancer Diagnosis with Machine Learning Using Feed-Forward Multilayer Perceptron Analog Artificial Neural Network
    Authors: B Djimeli-Tsajio Alain, KLT Silas, LT Jean-Pierre, N Thierry, GW Ejuh
    Year: 2024

 

  • Design and Implementation of a Digital Breath Alcohol Detection System with SMS Alert and Vehicle Tracking on Google Map
    Author: KLT Silas
    Year: 2020

 

  • Design and Realization of an Electronic Attendance System Based on RFID with an Automatic Door Unit
    Author: MK Jules
    Year: 2018

 

🎯 Conclusion

With a vision to transform medical physics through automation and AI-driven technologies, Koagne Longpa Tamo Silas is on a path to making significant contributions to healthcare innovation. His passion, dedication, and expertise ensure that his research will continue to shape the future of medical technology, leaving a lasting impact on both academia and practical applications in the field.