Mohamad-Reza Aghanoori | Neurodegenerative Disorders | Best Researcher Award

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Dr. Mohamad-Reza Aghanoori | Neurodegenerative Disorders | Best Researcher Award

Dr. Mohamad-Reza Aghanoori, National Institute of Genetic Engineering and Biotechnology,  Iran.

Dr. Mohamad-Reza Aghanouri is a distinguished neuroscientist and molecular medicine expert whose academic journey spans Iran and Canada. Beginning with foundational training in genetics and human biology, he has advanced into a dynamic career focused on translational neuroscience, particularly the genetic regulation of neurodevelopmental and neurodegenerative disorders. His doctoral and postdoctoral research have contributed significant insights into insulin/IGF-1 signaling, mitochondrial function, and gene expression related to autism and diabetic neuropathy.

Profile

Google Scholar

🎓 Early Academic Pursuits

Mohamad-Reza Aghanouri embarked on his academic journey with a B.Sc. in Cellular and Molecular Biology–Genetics from Shahid Chamran University of Ahvaz, Iran, in 2009. His keen interest in the intricate mechanics of human biology led him to pursue an M.Sc. in Human Genetics at Shiraz University of Medical Sciences, where he explored non-invasive techniques for early sex determination through free fetal DNA analysis. His growing passion for neuroscience and genetics culminated in a Ph.D. from the University of Manitoba, Canada, where he studied at the Department of Pharmacology and Therapeutics and the Division of Neurodegenerative Disorders. His doctoral thesis, focused on insulin/IGF-1 regulation of mitochondrial function in diabetic neuropathy, laid a strong foundation for a dynamic career in translational neurogenetics.

🧬 Professional Endeavors in Translational Neuroscience

Dr. Aghanouri’s postdoctoral work reflects a robust engagement with translational neuroscience and molecular medicine. From 2019 to 2024, he served as a postdoctoral fellow at the Department of Medical Genetics, Cumming School of Medicine, University of Calgary, under the mentorship of Dr. Guang Yang. His research investigated translational regulation of genes implicated in brain development, especially in autism spectrum disorders and rare neurodevelopmental conditions. Prior to that, he worked with Prof. Paul Fernyhough in Winnipeg, Canada, where he examined the role of IGF-1 in ATP production in sensory neurons under diabetic stress conditions. His diverse experience also includes a pivotal R&D advisory role at Roya Bio Gene Company in Tehran, showcasing his versatility across both academic and industrial biosciences.

🔬 Contributions and Research Focus

Dr. Aghanouri’s research contributions bridge the realms of neurodevelopment, metabolism, and genetic regulation. He has delved into the complex interplay between growth factors like IGF-1 and mitochondrial dynamics, particularly in relation to diabetic neuropathy. At the University of Calgary, his postdoctoral investigations explored the molecular pathways influencing neurodevelopmental disorders, positioning his work at the intersection of genomics and neuroscience. His methodological expertise spans cellular models, gene expression analysis, and translational bioinformatics, underscoring a commitment to discovering mechanisms that translate molecular findings into therapeutic insights.

🏆 Accolades and Recognition

Over the course of his academic and research career, Dr. Aghanouri has amassed a commendable list of honors. He received the prestigious CIHR postdoctoral fellowship (CA$40,000 annually, plus research allowance), along with additional fellowships from the Alberta Children’s Hospital Research Institute and the Cumming School of Medicine. Notably, he clinched first place in the Striking Image Competition at the University of Calgary and was honored by the BoniadMelliNokhbegan Foundation for his exceptional research talent. He has also earned multiple research grants from Iranian institutions in 2023 and 2024, reflecting his cross-border research impact and trust among funding bodies.

📚 Institutional Leadership and Influence

In 2024, Dr. Aghanouri was appointed as the Head of the Library, Documentation, Scientometrics, and Publication Center at the National Institute of Genetic Engineering and Biotechnology (NIGEB) in Tehran. He also holds a faculty position in the Department of Molecular Medicine at NIGEB. These roles position him as a key academic leader in Iran’s scientific community, where he not only continues his research but also shapes institutional research strategies, publication ethics, and scientific communication infrastructures. His work contributes significantly to Iran’s national bioscience and health research priorities.

🌍 Impact and Global Engagement

With academic roots in Iran and a decade of research training in Canada, Dr. Aghanouri exemplifies international scientific collaboration. His work addresses global health concerns, such as diabetes-induced neuropathies and neurodevelopmental disorders like autism, thus resonating with both clinical and scientific audiences worldwide. Through his active participation in conferences, poster competitions, and collaborative projects, he serves as a bridge between Iranian biotechnology advancements and the international research community.

🔮 Legacy and Future Contributions

Looking ahead, Dr. Aghanouri is poised to further advance the fields of molecular neurogenetics and translational medicine. His ongoing research is expected to uncover novel genetic mechanisms underlying brain development and metabolic dysfunctions. As a faculty member and research leader, he is mentoring the next generation of Iranian scientists while enhancing the global understanding of complex neurological diseases. His integrated approach to research, policy, and education ensures that his legacy will be one of both scientific innovation and institutional transformation.

Publication

 

  • Betulin and its derivatives as novel compounds with different pharmacological effects
    S Amiri, S Dastghaib, M Ahmadi, P Mehrbod, F Khadem, H Behrouj, …
    2020

 

  • Oxidized phosphatidylcholines trigger ferroptosis in cardiomyocytes during ischemia-reperfusion injury
    A Stamenkovic, KA O’Hara, DC Nelson, TG Maddaford, AL Edel, …
    2021

 

  • Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes
    MR Aghanoori, DR Smith, S Shariati-Ievari, A Ajisebutu, A Nguyen, …
    2019

 

  • The ER stress/UPR axis in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
    M Aghaei, S Dastghaib, S Aftabi, MR Aghanoori, J Alizadeh, P Mokarram, …
    2020

 

  • MiRNA molecular profiles in human medical conditions: Connecting lung cancer and lung development phenomena
    MR Aghanoori, B Mirzaei, M Tavallaei
    2014

 

  • Mechanisms targeting the unfolded protein response in asthma
    S Dastghaib, PS Kumar, S Aftabi, G Damera, A Dalvand, A Sepanjnia, …
    2021

 

  • Nucleocytoplasmic transport of the RNA-binding protein CELF2 regulates neural stem cell fates
    MJ MacPherson, SL Erickson, D Kopp, P Wen, MR Aghanoori, S Kedia, …
    2021

 

  • CYP2E15B, CYP2E16, CYP2E17B, CYP2E12, and CYP2E1*3 Allele Frequencies in Iranian Populations
    GM Shahriary, H Galehdari, A Jalali, F Zanganeh, SMR Alavi, …
    2012

 

  • Insulin prevents aberrant mitochondrial phenotype in sensory neurons of type 1 diabetic rats
    MR Aghanoori, DR Smith, SR Chowdhury, MG Sabbir, NA Calcutt, …
    2017

 

  • CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth
    MR Aghanoori, P Agarwal, E Gauvin, RS Nagalingam, R Bonomo, …
    2022

✅ Conclusion

Dr. Aghanouri stands out as a versatile and impactful scientist whose contributions to neuroscience and genetic medicine hold promise for both understanding and treating complex neurological conditions. His career reflects a strong blend of academic excellence, international collaboration, and leadership in research development. As he continues to build bridges between Iranian and global biosciences, his future work is expected to leave a lasting legacy in molecular neuroscience and translational medicine.

 

Mustafa Nazıroğlu | Cellular Neuroscience | Neuroscience Research Excellence Award

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Prof. Mustafa Nazıroğlu | Cellular Neuroscience | Neuroscience Research Excellence Award

Prof. Mustafa Nazıroğlu,  Suleyman Demirel University, Turkey.

Professor Mustafa Nazıroğlu is a distinguished scholar with dual doctorates in Physiology and Neuroscience. Beginning his academic journey at Fırat University and advancing to leadership roles at Süleyman Demirel University, he has become a global authority in the fields of oxidative stress, calcium signaling, and TRP ion channels. His research portfolio includes over 270 peer-reviewed articles and thousands of citations, showcasing a profound impact on cellular neuroscience. Beyond research, he has led major international congresses, served on editorial boards of top journals, and has been honored with numerous awards and fellowships in Europe, Asia, and North America.

Profile

Orcid

 

🎓 Early Academic Pursuits

Professor Mustafa Nazıroğlu embarked on his academic journey with a degree from the Faculty of Veterinary Medicine at Fırat University in 1991. Driven by a profound curiosity for physiological mechanisms, he pursued a Ph.D. in Physiology at the same institution, which he completed between 1992 and 1996. His academic ambitions later led him to earn a second Ph.D. in Neuroscience from Süleyman Demirel University (SDU) in 2018, reflecting his commitment to interdisciplinary scholarship and continuous learning.

🧠 Professional Endeavors in Neuroscience and Biophysics

Currently, Professor Nazıroğlu holds the position of Head of the Department of Biophysics and Neuroscience at SDU Medical Faculty. His professional path has been shaped by a deep dedication to academic leadership, having served in several key roles including department head, director of the Neuroscience Research Centre (NOROBAM), and chair of numerous international scientific congresses. Notably, he has successfully organized the biennial International World Congress of Oxidative Stress, Calcium Signalling and TRP Channels from 2006 to 2020, as well as the International Brain Research School series from 2015 to 2024. His influence has also reached global platforms, including service on the organizing committee for the TEMA-14 Congress in Hubei, China, in 2011.

🔬 Contributions and Research Focus

A prolific researcher, Professor Nazıroğlu has significantly advanced our understanding of oxidative stress, calcium signaling, apoptosis, and ion channel (TRP) physiology. His scientific output includes 274 international research articles, 19 review papers, and six book chapters, collectively amassing over 11,500 citations and earning him a Scopus h-index of 59. He has also contributed as an editorial and reviewing member for leading journals such as Biological Trace Element Research, Scientific Reports (Nature Publishing), Frontiers in Physiology, and Current Neuropharmacology, among others. His research has bridged cellular neuroscience with therapeutic strategies, making him a vital contributor to the global scientific discourse.

🏅 Accolades and Recognition

Throughout his career, Professor Nazıroğlu has received numerous national and international honors, celebrating his scientific achievements and global engagement. These include the NATO Research Fellowship (Germany), the Alexander von Humboldt Fellowship (Germany), and the Young Investigative Scientist Award (USA). He has also been recognized by the Turkish Scientific and Technological Research Council (TÜBİTAK), the Howard Hughes Medical Institute (USA), and was the recipient of the prestigious Khwarizmi International Award (Iran). His visiting professorships at institutions in the UK, Qatar, and Japan further underscore his international reputation and collaboration.

🌍 Impact and Influence

Professor Nazıroğlu’s impact extends beyond academic publishing and conference organization. As a mentor, speaker, and panel member, he has shaped the careers of young neuroscientists and fostered a collaborative global network of researchers in calcium signaling and oxidative biology. His participation in expert advisory boards and scientific panels illustrates the depth of his influence on both research policy and biomedical innovation.

📘 Legacy of Knowledge

With over three decades dedicated to science and education, Professor Nazıroğlu has built a lasting legacy grounded in scientific rigor and visionary leadership. His conferences and educational programs, especially the International Brain Research School, have become cornerstone events for knowledge exchange in neuroscience. He has laid a strong foundation for future advancements in TRP channel research and neurophysiology.

🚀 Future Contributions and Vision

Looking forward, Professor Nazıroğlu continues to guide critical research on cellular responses to oxidative stress and ion channel modulation. His forward-thinking approach, combined with an inclusive scientific philosophy, ensures that he remains a leading voice in shaping the next era of biomedical research. With ongoing collaborative projects and mentorship of emerging scholars, his work is poised to influence both clinical and theoretical frontiers for years to come.

Publication

 

  • Title: Vitamin D Supplementation Modulates Blood and Tissue Zinc, Liver Glutathione and Blood Biochemical Parameters in Diabetic Rats on a Zinc-Deficient Diet
    Authors: Kechrid, Z.; Hamdiken, M.; Nazıroğlu, M.; Flores-Arce, M.
    Year: 2023

 

  • Title: Low molecular weight heparin treatment reduced apoptosis and oxidative cytotoxicity in the thrombocytes of patients with recurrent pregnancy loss and thrombophilia: Involvements of TRPM2 and TRPV1 channels
    Authors: Dal, Y.; Nazıroğlu, M.; Özkaya, M.O.
    Year: 2023

 

  • Title: NMDA Receptor Activation Stimulates Hypoxia-Induced TRPM2 Channel Activation, Mitochondrial Oxidative Stress, and Apoptosis in Neuronal Cell Line: Modular Role of Memantine
    Authors: Kenan Yıldızhan; Mustafa Nazıroğlu
    Year: 2023

 

  • Title: Honey bee venom melittin increases the oxidant activity of cisplatin and kills human glioblastoma cells by stimulating the TRPM2 channel
    Authors: Kemal Ertilav; Mustafa Nazıroğlu
    Year: 2023

 

  • Title: Silver nanoparticles potentiate antitumor and oxidant actions of cisplatin via the stimulation of TRPM2 channel in glioblastoma tumor cells
    Authors: Yener Akyuva; Mustafa Nazıroğlu
    Year: 2023

 

  • Title: A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol
    Author: Nazıroğlu, M.
    Year: 2022

 

  • Title: Amantadine Attenuated Hypoxia-Induced Mitochondrial Oxidative Neurotoxicity, Apoptosis, and Inflammation via the Inhibition of TRPM2 and TRPV4 Channels
    Authors: Öcal, Ö.; Coşar, A.; Nazıroğlu, M.
    Year: 2022

 

  • Title: Eicosapentaenoic acid enhanced apoptotic and oxidant effects of cisplatin via activation of TRPM2 channel in brain tumor cells
    Authors: Öcal, Ö.; Nazıroğlu, M.
    Year: 2022

 

  • Title: Paclitaxel Promotes Oxidative Stress–Mediated Human Laryngeal Squamous Tumor Cell Death through the Stimulation of Calcium and Zinc Signaling Pathways: No Synergic Action of Melatonin
    Authors: Kumbul, Y.Ç.; Nazıroğlu, M.
    Year: 2022

 

  • Title: Protective role of selenium on MPP⁺ and homocysteine-induced TRPM2 channel activation in SH-SY5Y cells
    Authors: Yıldızhan, K.; Nazıroğlu, M.
    Year: 2022

 

🧾 Conclusion

Through an outstanding blend of academic excellence, innovative research, and global collaboration, Professor Nazıroğlu has carved a legacy as a leading figure in neuroscience and biophysics. His efforts in organizing international platforms and mentoring young scientists reflect a career committed to advancing knowledge and fostering global scientific networks. With continued contributions and visionary leadership, he remains a driving force in shaping the future of cellular neurophysiology and therapeutic discovery.

Gilles Rode | Clinical Neuroscience | Best Researcher Award

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Prof. Gilles Rode | Clinical Neuroscience | Best Researcher Award

Dr. Gilles Rode is a distinguished figure in the field of Physical Medicine and Rehabilitation (PMR), holding significant positions at both academic and clinical institutions in France. His career spans decades, with a strong foundation built on his dual M.D. and Ph.D., which paved the way for his pioneering work in neuroplasticity and motor rehabilitation. As the Head of the Department of Rehabilitation at Hôpital Henry Gabrielle and the Dean of the Faculty of Medicine Lyon-Est, he has contributed extensively to the development of rehabilitation practices, medical education, and research. Dr. Rode’s research focuses on understanding neurological recovery and enhancing rehabilitation techniques for patients with brain injuries, while his leadership roles in organizations like the French Society of Physical Medicine and Rehabilitation (Sofmer) and the European Academy of Rehabilitation and Physical Medicine underscore his impact on a global scale.

Profile

Scopus

 

Early Academic Pursuits 📚


Gilles Rode’s academic journey began with a strong foundation in medicine and physical rehabilitation, which led him to pursue a dual M.D. and Ph.D. This unique combination of clinical and scientific expertise laid the groundwork for his exceptional career. His training at esteemed institutions in France, particularly at Université Claude Bernard Lyon 1, has enabled him to delve deeply into the complexities of physical medicine and rehabilitation (PMR). It was during this phase that Dr. Rode developed an interest in combining clinical work with cutting-edge research, exploring the rehabilitation processes from both medical and scientific perspectives.

Professional Endeavors 🏥


In his professional career, Dr. Rode has held pivotal roles in both clinical and academic settings. Since 2009, he has served as the Head of the Department of Rehabilitation at Hôpital Henry Gabrielle, part of the Hospices Civils de Lyon. This role allowed him to shape the development of rehabilitation practices within a leading French hospital. Furthermore, between 2009 and 2016, he contributed significantly as the Vice-Dean at the Faculty of Medicine Lyon-Est, Université Claude Bernard Lyon 1, a position that gave him a platform to influence medical education. His leadership and vision have consistently propelled the field forward, particularly in the integration of advanced rehabilitation techniques into patient care.

Contributions and Research Focus 🔬

Dr. Rode’s research has consistently focused on enhancing physical rehabilitation methods, particularly for individuals recovering from neurological impairments. His scientific inquiries are centered on understanding the mechanisms of neuroplasticity and recovery in brain-injured patients. As a leading member of the Centre de Recherche en Neurosciences de Lyon, his work integrates neuroscience with rehabilitation science, aiming to improve clinical practices and outcomes. His pioneering studies on motor rehabilitation and the use of innovative techniques for brain injury recovery have earned him recognition within both the scientific and medical communities.

Accolades and Recognition 🏅


Dr. Rode’s commitment to advancing the field of physical medicine and rehabilitation has been recognized through numerous accolades. He served as the President of the French Society of Physical Medicine and Rehabilitation (Sofmer) from 2013 to 2016, a position that allowed him to advocate for the integration of contemporary rehabilitation approaches in French healthcare. In 2015, he was elected as a member of the European Academy of Rehabilitation and Physical Medicine, further cementing his status as a leader in the field. His leadership roles and scientific contributions have earned him significant recognition both nationally and internationally.

Impact and Influence 🌍


Dr. Rode’s impact extends far beyond his clinical and academic roles. His work has influenced policies in rehabilitation medicine and has set standards for how rehabilitation should be practiced in hospital settings. As the Dean of the Faculty of Medicine Lyon-Est, he has been at the forefront of shaping medical curricula to ensure that the next generation of doctors is well-equipped to address the challenges of rehabilitation medicine. His ability to bridge the gap between research and clinical practice has resulted in more effective therapies and patient outcomes, impacting countless lives.

Legacy and Future Contributions 🔮


As Dr. Rode continues his work, his legacy is one of both clinical excellence and scientific innovation. His research has had a lasting effect on how physical medicine and rehabilitation are perceived in the medical community. Moving forward, Dr. Rode is expected to continue influencing the development of rehabilitation therapies, particularly in the areas of neuroplasticity and motor recovery. His future contributions will undoubtedly build on the foundation he has established, ensuring that patients continue to benefit from the evolving advancements in rehabilitation medicine.

Global Influence and Leadership 🌐


Dr. Rode’s reputation extends beyond the borders of France, as he is often invited to share his expertise at international conferences and seminars. His leadership in both academia and professional societies has made him a global voice in rehabilitation. Through his active involvement in the European Academy of Rehabilitation and Physical Medicine, he continues to contribute to the global exchange of ideas, driving the evolution of rehabilitation practices across Europe and beyond. Dr. Rode’s influence is not just felt in France but is also shaping the future of rehabilitation medicine worldwide.

Publication

  • Title: Determining the influence of a sleep improvement intervention on medical students’ sleep and fatigue: protocol of the PROMESS-Sleep clinical trial
    Authors: Ruet, Axelle; Ndiki Mayi, Evrard Florentin; Métais, Angèle; Rode, Gilles; Schlatter, Sophie T.
    Year: 2025

 

  • Title: Determining the influence of an intervention of stress management on medical students’ levels of psychophysiological stress: the protocol of the PROMESS-Stress clinical trial
    Authors: Métais, Angèle; Omarjee, Mohammad; Valero, Bérénice; Rode, Gilles; Schlatter, Sophie T.
    Year: 2025

 

  • Title: Co-administration of methylphenidate and prism adaptation would require striatal integrity to alleviate spatial neglect: A preliminary study
    Authors: Beaudoin-Gobert, Maude; Benistant, Faustine; de Lanversin, Maxence; Rossetti, Yves; Luauté, Jacques
    Year: 2024 (presumed, not listed but grouped contextually)

 

  • Title: Updates on post-stroke rehabilitation
    Authors: Charbonnier, Geoffroy; Bihel, Lucie; Jacquin-Courtois, Sophie; Rode, Gilles; Mateo, Sébastien
    Year: 2024 (presumed)

 

  • Title: Effect of coping interventions on performance of medical students during objective structured clinical examination: A randomized controlled trial
    Authors: Schlatter, Sophie T.; Berland, Alexandre; Lutz, Antoine; Rode, Gilles; Lilot, Marc E.
    Year: 2025

 

  • Title: Associations of coping and health-related behaviors with medical students’ well-being and performance during objective structured clinical examination
    Authors: Barret, Noémie; Guillaumée, Théodore; Rimmelé, Thomas R.; Lilot, Marc E.; Schlatter, Sophie T.
    Year: 2024

 

  • Title: Grasping rehabilitation using motor imagery with or without neurofeedback after tetraplegia: A study protocol for a bicentric randomised controlled trial
    Authors: Charbonnier, Geoffroy; Reilly, Karen T.; Schwartz, Denis P.; Rode, Gilles; Mateo, Sébastien
    Year: 2024

 

  • Title: Neck muscle vibration and prism adaptation fail to improve balance disturbances after stroke: A multicentre randomised controlled study
    Authors: Leplaideur, Stephanie; Allart, Etienne; Chochina, Lucie; Bannier, Élise; Bonan, Isabelle Véronique
    Year: 2024

 

  • Title: Striking the Balance: Embracing Technology While Upholding Humanistic Principles in Neurorehabilitation
    Authors: Ardaillon, Hugo; Ribault, Shams; Herault, Caroline; Reilly, Karen T.; Rode, Gilles
    Year: 2024

 

  • Title: Implicit and explicit motor imagery ability after SCI: Moving the elbow makes the difference
    Authors: Mateo, Sébastien; Guillot, Aymeric; Henkous, Sonia; Collet, Christian; Di Rienzo, Franck
    Year: 2024

 

Conclusion


Dr. Gilles Rode’s work has left an indelible mark on the field of rehabilitation, where his contributions have influenced both clinical practices and academic curricula. His dedication to improving patient outcomes through innovative rehabilitation methods, combined with his leadership and advocacy in professional societies, ensures that his influence will continue for years to come. As he progresses in his career, Dr. Rode remains a key figure in advancing the field of physical medicine and rehabilitation, shaping both the future of patient care and the next generation of healthcare professionals. His legacy will continue to inspire progress in rehabilitation science, benefiting countless individuals across the globe.