Peng Jun | Cellular Neuroscience | Best Researcher Award

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Prof. Peng Jun | Cellular Neuroscience | Best Researcher Award

Prof. Peng Jun, Qilu hospital of Shandong University, China.

Professor Jun Peng is a distinguished leader in hematology, currently serving as Vice President of Qilu Hospital of Shandong University and Director of the Department of Hematology. His research is deeply rooted in the immunological pathogenesis and immune tolerance of primary immune thrombocytopenia (ITP), where he has made significant breakthroughs, including the publication of 14 papers in Blood. With a career supported by prestigious national awards, and leadership in 15 high-level research projects, Professor Peng is also a vital figure in Chinese hematology societies and editorial boards of leading journals. His academic rigor, clinical insight, and mentorship continue to shape the future of hematological science in China and beyond.

Profile

Scopus

🎓 Early Academic Pursuits

Professor Jun Peng embarked on his academic journey with a strong commitment to medicine and hematological sciences. From the outset, he exhibited exceptional academic talent and dedication, leading him to pursue both an M.D. and Ph.D. His early education laid a robust foundation for his future specialization in hematology, particularly in the complex field of immunological disorders. His doctoral work, recognized nationally, foreshadowed the groundbreaking contributions he would later make in immune thrombocytopenia research.

đź©ş Professional Endeavors

Currently serving as the Vice President of Qilu Hospital of Shandong University, Professor Peng also holds the roles of Chief Physician, Professor, and Ph.D./M.D. Advisor, in addition to being the Director of the Department of Hematology. His clinical and academic responsibilities are carried out with unwavering diligence, mentoring future medical experts while overseeing high-level clinical operations. As a Distinguished Professor of Shandong University, he is actively engaged in shaping the university’s medical excellence on both national and global stages.

🔬 Contributions and Research Focus

At the heart of Professor Peng’s career is his pioneering work on the immunological pathogenesis and immune tolerance of primary immune thrombocytopenia (ITP). He has made substantial contributions to understanding the autoimmune mechanisms that underlie ITP, one of the most challenging hematologic disorders. His scholarly dedication is evidenced by the publication of 14 papers in Blood, a leading journal in hematology, where he served as corresponding or co-corresponding author. His research, grounded in clinical insight and scientific precision, has contributed new perspectives on immune regulation in hematologic diseases.

🏆 Accolades and Recognition

Professor Peng’s excellence has been recognized with numerous prestigious awards. These include the National Science Fund for Distinguished Young Scholars, which highlights his scientific creativity and impact at a young age. He is also a recipient of the One-Hundred National Outstanding Doctoral Dissertation Award, a testament to the academic rigor of his early research. Additionally, he earned the First Prize of the Natural Science Award for Outstanding Achievements in Scientific Research from the Ministry of Education and the Science and Technology Progress Award, reflecting both his academic brilliance and practical impact in the medical field.

🧪 Impact and Influence

Beyond research publications, Professor Peng has significantly influenced the broader scientific and medical communities. As a principal investigator, he has led fifteen national and ministerial-level research projects, including those funded by the National Natural Science Foundation of China and the 973 Program under the Ministry of Science and Technology. His leadership extends to active roles in national academic societies, including the Thrombosis and Hemostasis Group of the Chinese Society of Hematology and the Professional Committee of Experimental Hematology of the Chinese Society of Pathophysiology. These positions allow him to shape the direction of hematological research and clinical guidelines in China.

đź“š Academic Leadership and Editorial Roles

A passionate advocate for knowledge dissemination, Professor Peng is a key editorial board member for several respected journals such as Thrombosis Journal, Thrombosis Research, Journal of Clinical Hematology, and the Chinese Journal of Hematology. Through these roles, he ensures that cutting-edge research in hematology is critically evaluated and shared widely, fostering a culture of scientific excellence and collaboration across the globe.

🌟 Legacy and Future Contributions

Professor Jun Peng’s legacy is being forged not only through his past achievements but also through his continued commitment to the advancement of hematological science. His influence spans clinical innovation, academic mentorship, and scientific discovery. As he continues to push the boundaries of understanding in ITP and immune tolerance, he inspires a new generation of physician-scientists. The impact of his work promises to resonate for years to come, offering hope and healing for patients and propelling China’s medical research onto the world stage.

Publication

  • Title: Autoimmune effector mechanisms associated with a defective immunosuppressive axis in immune thrombocytopenia (ITP)
    Authors: Qizhao Li, Geneviève Marcoux, Yuefen Hu, Jung Peng, John W. Semple
    Year: 2024

 

  • Title: Quantitative detection of macular microvascular abnormalities identified by optical coherence tomography angiography in different hematological diseases
    Authors: Tianzi Jian, Fabao Xu, Guihua Li, Li Zhang, Jung Peng
    Year: 2024

 

  • Title: Nicotinamide enhances Treg differentiation by promoting Foxp3 acetylation in immune thrombocytopenia
    Authors: Ju Li, Cheng Zhang, Yuefen Hu, Qi Feng, Xiang Hu
    Year: 2024

 

  • Title: The effects of complement-independent, autoantibody-induced apoptosis of platelets in immune thrombocytopenia (ITP)
    Authors: Lin Sun, Yichen Zhang, Ping Chen, Jung Peng, Zi Sheng
    Year: 2024

 

  • Title: Post-transplant lymphoproliferative disorders after allogeneic hematopoietic stem cell transplantation: a case report, meta-analysis, and systematic review
    Authors: You Yuan Su, Yafei Yu, Zhenyu Yan, Jung Peng, Xinguang Liu
    Year: 2024

 

  • Title: Ion channel Piezo1 activation aggravates the endothelial dysfunction under a high glucose environment
    Authors: Xiaoyu Zhang, Shaoqiu Leng, Xinyue Liu, Shuwen Wang, Jung Peng
    Year: 2024

 

  • Title: Intelligent dual-modality label-free cell classification with light scattering imaging and Raman spectra measurements
    Authors: Faihaa Mohammed Eltigani, Xiaoyu Zhang, Min Liu, Jung Peng, Xuantao Su
    Year: 2024

 

  • Title: Eltrombopag plus diacerein vs eltrombopag in patients with ITP: a multicenter, randomized, open-label phase 2 trial
    Authors: Lu Sun, Xiaoyang Huang, Juan Wang, Ming Hou, Yu Hou
    Year: 2024

 

  • Title: Risk Factors for Mortality in Critically Ill Patients with Coagulation Abnormalities: A Retrospective Cohort Study
    Authors: Qiuyu Guo, Jung Peng, Tichao Shan, Miao Xu
    Year: 2024

 

  • Title: Platelet-derived TGF-β1 induces functional reprogramming of myeloid-derived suppressor cells in immune thrombocytopenia
    Authors: Lingjun Wang, Haoyi Wang, Mingfang Zhu, Ming Hou, Yu Hou
    Year: 2024

 

âś… Conclusion

Through his pioneering research, unwavering clinical dedication, and impactful academic leadership, Professor Jun Peng stands at the forefront of immuno-hematology. His work not only deepens scientific understanding of ITP but also contributes directly to improved patient outcomes. As he continues to inspire through teaching, research, and innovation, Professor Peng’s legacy is one of excellence, influence, and ongoing transformation in the global hematology community.

 

Paolo Grumati | Cell Biology | Best Researcher Award

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Prof. Paolo Grumati | Cell Biology | Best Researcher Award

Prof. Paolo Grumati,  TIGEM, Italy.

Dr. Paolo Grumati is a prominent researcher and academic with a focus on molecular biology, particularly the study of autophagy and its role in diseases such as muscular dystrophies and neurodegenerative disorders. His academic journey, beginning with a Master’s and Ph.D. from the University of Padova, laid the foundation for his pioneering work in the molecular mechanisms underlying disease pathogenesis. Dr. Grumati’s professional endeavors have included roles at esteemed institutions like Johann Wolfgang Goethe University and the Telethon Institute of Genetics and Medicine (TIGEM), where he leads groundbreaking research in selective autophagy. His work, which integrates advanced techniques like CRISPR/Cas9, has earned him widespread recognition and numerous accolades, including positions as Associate Professor at the University of Naples. His research has had a significant impact on the scientific community, particularly in the areas of cellular maintenance and therapeutic development.

Profile

Scopus

 

Early Academic Pursuits 🎓


Paolo Grumati’s academic journey began at the University of Padova in Italy, where he pursued a Master’s Degree in Medical Biotechnologies, graduating in 2005. His deep curiosity in the molecular underpinnings of human biology led him to continue his studies with a Ph.D. in Genetic and Molecular Biology, completed between 2006 and 2009. During his Ph.D., he focused on the genetic mechanisms that contribute to various diseases, a pursuit that sparked his lasting interest in molecular biology and disease pathogenesis. His early academic training laid a strong foundation for his future research in the biochemistry of diseases, especially those that affect muscle function and cellular processes.

Professional Endeavors đź’Ľ


Dr. Grumati’s professional career has been marked by an impressive trajectory across prestigious institutions. After completing his postdoctoral work on the pathogenesis of muscular dystrophies at the University of Padova, he moved to Germany, where he took a position at the Institute of Biochemistry II at Johann Wolfgang Goethe University. There, between 2013 and 2018, he specialized in the biochemistry and molecular biology of autophagy, a crucial cellular process related to health and disease. His expertise in autophagy became a defining element of his career, and in 2019, he was appointed as the Assistant Investigator and Head of the Mass Spectrometry Core at the Telethon Institute of Genetics and Medicine (TIGEM), where he leads innovative research into the molecular mechanisms of selective autophagy. Throughout these roles, Dr. Grumati has built a reputation for integrating advanced techniques like CRISPR/Cas9 into his work, influencing the field of genetic research.

Contributions and Research Focus 🔬


Dr. Grumati’s research focus has consistently revolved around the intricate molecular processes that govern cellular maintenance and disease, particularly through the lens of autophagy. Since becoming a principal investigator in 2019, his work at TIGEM has concentrated on understanding the molecular mechanisms of selective autophagy, which plays a pivotal role in cellular health and disease. He has pioneered methods to study and manipulate these processes, contributing significantly to the understanding of diseases such as muscular dystrophies and neurodegenerative disorders. His research not only delves into the underlying biology of these conditions but also seeks to identify therapeutic targets that could help manage or even cure these diseases.

Accolades and Recognition 🏆


Dr. Grumati has received widespread recognition for his work in molecular biology and biochemistry. His contributions to the field of autophagy and muscle biology have been honored with leadership roles in prominent research teams, including his time as Team Leader of the Frankfurt CRISPR/Cas9 Screening Center. His excellence in research has earned him a faculty position as Assistant Professor at the University of Naples “Federico II” and an eventual promotion to Associate Professor in 2024. His expertise in mass spectrometry and molecular biology has also made him a sought-after figure in the scientific community, where he is frequently invited to collaborate on interdisciplinary research projects.

Impact and Influence 🌍


Dr. Grumati’s research has had a lasting impact on the scientific community, particularly in the fields of autophagy and muscular dystrophies. His work has influenced both theoretical and applied aspects of molecular biology, from basic research to potential therapeutic interventions. Through his leadership at TIGEM and his involvement in international collaborations, Dr. Grumati has helped to shape the direction of research into autophagy-related diseases. His studies have not only provided insights into the cellular mechanisms at play in these diseases but also paved the way for future therapeutic strategies. He is seen as a key figure in the advancement of precision medicine and molecular therapeutics.

Legacy and Future Contributions đź”®

As Dr. Grumati moves forward in his career, his contributions to the fields of genetics and molecular biology are expected to have a profound and lasting influence. His current work, focusing on selective autophagy, holds promise for the development of novel treatments for diseases that currently have limited therapeutic options. His legacy will likely include innovations in understanding cellular degradation processes and their application to genetic disorders and other diseases. The future of Dr. Grumati’s research will continue to explore the molecular intricacies of human health, offering the potential for breakthroughs in regenerative medicine and disease treatment.

Teaching and Mentorship 👨‍🏫


Beyond his research, Dr. Grumati has made a significant impact through his academic roles at the University of Naples. As an Associate Professor, he plays a key role in shaping the next generation of molecular biologists. His teaching focuses on imparting knowledge in genetics, biochemistry, and molecular biology, with an emphasis on practical research applications. His mentorship has helped guide many students and early-career researchers, who have gone on to make their own contributions to the field. Dr. Grumati’s ability to translate complex scientific concepts into accessible lessons ensures that his influence extends far beyond his own research.

Publication

  • Title: Cortico-striatal circuit mechanisms drive the effects of D1 dopamine agonists on memory capacity in mice through cAMP/PKA signalling
    Authors: M. de Risi, D. Cavezza, G. Torromino, P. Grumati, E. de Leonibus
    Year: 2025

 

  • Title: Two FAM134B isoforms differentially regulate ER dynamics during myogenesis
    Authors: V. Buonomo, K.O. Lohachova, A. Reggio, R.M. Bhaskara, P. Grumati
    Year: 2025

 

  • Title: Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling
    Authors: G. Giamundo, D. Intartaglia, E. del Prete, R. De Cegli, I. Conte
    Year: 2025

 

  • Title: 3D Rotary Wet-Spinning (RoWS) Biofabrication Directly Affects Proteomic Signature and Myogenic Maturation in Muscle Pericyte–Derived Human Myo-Substitute
    Authors: A. Reggio, C. Fuoco, F. de Paolis, M. Costantini, C. Gargioli
    Year: 2025

 

  • Title: Cross-Linking Mass Spectrometry to Capture Protein Network Dynamics of Cell Membranome
    Authors: L. Santorelli, M. Costanzo, S. Petrosino, M. Ruoppolo, P. Grumati
    Year: 2025

 

  • Title: Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces
    Authors: P. Romani, G. Benedetti, M. Cusan, G. Martello, S. Dupont
    Year: 2024

 

Conclusion


Dr. Paolo Grumati’s career exemplifies the integration of scientific inquiry with practical application, as his research continues to shed light on crucial molecular processes that affect human health. His contributions to the understanding of autophagy have opened new avenues for potential therapeutic strategies in treating genetic disorders and other diseases. As he continues to lead research at TIGEM and teach at the University of Naples, Dr. Grumati’s legacy is set to influence the fields of molecular biology, genetics, and medicine for years to come. His work remains pivotal in advancing both the theoretical understanding of disease mechanisms and the development of new therapeutic approaches, positioning him as a key figure in modern biomedical research.