Irena Roterman | Computational Neuroscience | Best Researcher Award

Prof. Dr. Irena Roterman | Computational Neuroscience | Best Researcher Award

Prof. Dr. Irena Roterman, Jagiellonian University Medical College, Poland.

Prof. Irena Roterman-Konieczna is a distinguished scientist whose academic roots in theoretical chemistry and biochemistry evolved into groundbreaking contributions in bioinformatics. With a Ph.D. and habilitation in biochemistry, and a postdoctoral fellowship at Cornell University, she developed a unique perspective on protein structure and folding. Her most notable innovation is the Fuzzy Oil Drop (FOD) model, which simulates protein folding by incorporating environmental effects using a 3D Gaussian function to map hydrophobicity distribution. This model has wide applicability—from understanding membrane proteins and amyloids to analyzing domain-swapping and receptor anchoring.

Profile

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🎓 Early Academic Pursuits

Irena Roterman-Konieczna began her academic journey in theoretical chemistry at the prestigious Jagiellonian University, graduating from the Faculty of Chemistry in 1974. Her early interest in molecular structure and the physicochemical underpinnings of biological systems laid a strong foundation for her interdisciplinary career. She deepened her scientific expertise by earning a Ph.D. in biochemistry in 1984 from Nicolaus Copernicus Medical Academy in Krakow, focusing on the structure of the recombinant IgG hinge region. Her postdoctoral studies at Cornell University from 1987 to 1989, under the mentorship of Harold A. Scheraga, further shaped her academic development. There, she explored force fields used in prominent computational programs like AMBER, CHARMM, and ECEPP, bridging theoretical modeling with biomolecular reality.

🧬 Professional Endeavors in Bioinformatics

Throughout her career, Prof. Roterman-Konieczna has been at the forefront of bioinformatics, dedicating herself to unraveling the mysteries of protein structure and amyloid formation. Following her habilitation in biochemistry at the Jagiellonian University Faculty of Biotechnology in 1994 and the conferment of her professorial degree in medical sciences in 2004, she continued to pioneer innovative methods in structural bioinformatics. Her hallmark contribution, the Fuzzy Oil Drop (FOD) model, revolutionized the understanding of protein folding. The model uniquely incorporates environmental influence into folding simulations by using a 3D Gaussian function to describe hydrophobicity distribution—proposing that hydrophobic residues form a central core while hydrophilic residues remain exposed. This paradigm introduced a more realistic, dynamic framework for simulating in silico protein folding.

đŸ§Ș Contributions and Research Focus

Prof. Roterman-Konieczna’s research has explored how proteins behave not only in aqueous environments but also within membranes and under the influence of external force fields. By modifying the Gaussian-based FOD model, she extended its applicability to membrane proteins, enabling quantification of their anchoring mechanisms and mobility. Her investigations into chaperonins and domain-swapping phenomena further illustrate the power of her model to decode complex folding and protein-protein interactions. She introduced a dual-variable simulation function—accounting for both internal forces (non-bonded interactions within the protein chain) and external forces (environmental effects)—to guide structural transformation toward energy minima. These ideas are foundational in modern computational biology, where realistic folding predictions are critical for understanding disease mechanisms and therapeutic targeting.

📘 Scholarly Publishing and Intellectual Outreach

A prolific author, Prof. Roterman-Konieczna has made significant contributions to scientific literature. She has authored several influential books, many published in Open Access to promote knowledge sharing. These works include “Protein Folding In Silico” (Elsevier), “Systems Biology – Functional Strategies of Living Organism” (Springer), and “From Globular Proteins to Amyloids” (Elsevier, 2020). Her books elegantly communicate complex bioinformatic strategies, such as ligand binding site identification, protein-protein interactions, and computer-aided diagnostics. Moreover, her editorial leadership from 2005 to 2020 as Chief Editor of the journal Bio-Algorithms and Med-Systems cemented her influence in shaping interdisciplinary dialogues at the intersection of medicine, biology, and computation.

🏆 Accolades and Recognition

Prof. Roterman-Konieczna’s work has earned international acclaim. Notably, she is listed among the Top 2% scientists worldwide by Stanford University and Elsevier—a testament to her influential research and academic reputation. With 149 publications indexed in PubMed, her impact on the bioinformatics community is both broad and profound. Over the course of her career, she has also served as a mentor to 14 doctoral students, many of whom continue to contribute to research and innovation across various fields of biomedicine.

🌐 Impact and Influence

Her research has advanced global understanding of how proteins fold, interact, and misfold—a process central to neurodegenerative diseases such as Alzheimer’s. The FOD model continues to provide a computational lens for studying amyloid formation and supramolecular assemblies. Her model is also pivotal in studying receptor anchoring in membranes and exploring domain-swapping mechanisms critical to protein complex formation. By integrating thermodynamic theory, statistical modeling, and structural biology, her work bridges theoretical research with biomedical applications, pushing the boundaries of in silico experimentation.

🧭 Legacy and Future Contributions

Prof. Irena Roterman-Konieczna’s legacy is rooted in her visionary approach to molecular biology, championing models that blend computational precision with biological realism. Her commitment to open access publishing and academic mentoring reflects a deep dedication to inclusive, sustainable scientific progress. As systems biology and personalized medicine continue to evolve, her models and insights will remain cornerstones for future explorations in disease modeling, drug design, and molecular diagnostics. Her career exemplifies how interdisciplinary thinking and computational ingenuity can transform the life sciences, leaving a legacy that will guide future generations of scientists.

Publication

  • Title: Aquaporins as Membrane Proteins: The Current Status
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), D. DuƂak (Dawid), G. Szoniec (Grzegorz), L. Konieczny (Leszek)
    Year: 2025

 

  • Title: DisorderUnetLM: Validating ProteinUnet for efficient protein intrinsic disorder prediction
    Authors: K. Kotowski (Krzysztof), I.K. Roterman (Irena K.), K. Stapor (Katarzyna)
    Year: 2025

 

  • Title: Protein folding: Funnel model revised
    Authors: I.K. Roterman (Irena K.), M. Slupina (Mateusz), L. Konieczny (Leszek)
    Year: 2024

 

  • Title: Domain swapping: a mathematical model for quantitative assessment of structural effects
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), D. DuƂak (Dawid), L. Konieczny (Leszek)
    Year: 2024

 

  • Title: Chameleon Sequences─Structural Effects in Proteins Characterized by Hydrophobicity Disorder
    Authors: I.K. Roterman (Irena K.), M. Slupina (Mateusz), K. Stapor (Katarzyna), K. Gądek (Krzysztof), P. Nowakowski (Piotr)
    Year: 2024

 

  • Title: Transmembrane proteins—Different anchoring systems
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), L. Konieczny (Leszek)
    Year: 2024

 

  • Title: External Force Field for Protein Folding in Chaperonins─Potential Application in In Silico Protein Folding
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), D. DuƂak (Dawid), L. Konieczny (Leszek)
    Year: 2024

 

  • Title: Structural features of Prussian Blue-related iron complex FeT of activity to peroxidate unsaturated fatty acids
    Authors: M. Lasota (MaƂgorzata), G. Zemanek (Grzegorz), O. Barczyk-WoĆșnicka (Olga), L. Konieczny (Leszek), I.K. Roterman (Irena K.)
    Year: 2024

 

  • Title: Editorial: Structure and function of trans-membrane proteins
    Authors: I.K. Roterman (Irena K.), M.M. Brylinski (Michal Michal), F. Polticelli (Fabio), A.G. de Brevern (Alexandre G.)
    Year: 2024

 

  • Title: Model of the external force field for the protein folding process—the role of prefoldin
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), L. Konieczny (Leszek)
    Year: 2024

 

🧠 Conclusion

Prof. Roterman-Konieczna’s career stands as a testament to how deep scientific insight and computational innovation can revolutionize biological understanding. Her FOD model not only enriches the study of protein dynamics but also provides a versatile framework for medical and pharmaceutical applications. With a legacy built on rigorous research, educational outreach, and academic leadership, her influence will continue to guide future advances in molecular biology, bioinformatics, and biomedical science.

 

İlyas UÇAR | Neuroimaging | Trailblazer in Neuroscience Award

Assoc.Prof.Dr. Ilyas UÇAR | Neuroimaging | Trailblazer in Neuroscience Award

Assoc. Prof. Dr. Ilyas UÇAR,  Erciyes University, Turkey.

İlyas Uçar is a dedicated academic and researcher specializing in anatomical sciences, particularly in developmental anatomy and teratology. His academic journey began with a Bachelor’s degree in Physiotherapy and Rehabilitation, followed by a Master’s and Ph.D. in Anatomy (Medicine) from Erciyes University. His research has focused on the effects of pharmaceutical agents such as Interferon and Paracetamol on embryonic and fetal development, shedding light on critical concerns regarding drug safety during pregnancy. As an Associate Professor, he has contributed to academia through teaching, mentorship, and interdisciplinary research, earning recognition for his impactful work. His studies have influenced medical guidelines and inspired  further research into prenatal health.

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📚 Early Academic Pursuits

İlyas Uçar embarked on his academic journey with a deep-rooted interest in health sciences, particularly in the intricate mechanisms of human anatomy. He earned his Bachelor’s degree in Physiotherapy and Rehabilitation from Abant İzzet Baysal University in 2007, where he developed a strong foundation in musculoskeletal function and rehabilitation techniques. His passion for understanding the human body at a deeper level led him to pursue postgraduate studies, marking the beginning of an extensive academic exploration.

His pursuit of higher education continued at Erciyes University, where he completed his Master’s degree in Anatomy (Medicine) in 2014. Under the guidance of Doç. Dr. Tolga Ertekin, he conducted groundbreaking research on the effects of Interferon beta-1a (IFNÎČ-1A) and Interferon beta-1b (IFNÎČ-1B) on in vitro embryonic development. This study not only refined his expertise in developmental anatomy but also set the stage for his future contributions to teratology and embryological research.

đŸ„ Professional Endeavors

With a strong academic foundation, İlyas Uçar transitioned into professional academia, where he merged his passion for teaching with his commitment to scientific discovery. His doctoral studies at Erciyes University’s Institute of Health Sciences were a significant milestone, culminating in his Ph.D. in Anatomy (Medicine) in 2018. His dissertation, supervised by Prof. Dr. Erdoğan Unur, explored the potential teratogenic effects of paracetamol on fetal bone development, shedding light on critical concerns regarding prenatal medication exposure.

Following his doctoral achievements, he took on an active role in academia, mentoring students and engaging in interdisciplinary research. His teaching methods, rooted in both theoretical knowledge and practical application, have made a lasting impact on students specializing in anatomy and health sciences.

🔬 Contributions and Research Focus

İlyas Uçar’s research focuses on developmental anatomy, particularly the impact of pharmaceutical agents on embryonic and fetal growth. His studies on interferons and paracetamol have contributed valuable insights into the possible risks associated with commonly used medications during pregnancy. Through meticulous experimental methodologies, he has explored the implications of these substances on skeletal formation, paving the way for further advancements in medical safety guidelines.

In addition to his work in teratology, he has delved into the broader aspects of anatomical sciences, bridging the gap between clinical applications and fundamental research. His interdisciplinary approach has fostered collaborations with medical professionals, physiologists, and pharmacologists, further enriching the field of health sciences.

🏅 Accolades and Recognition

Throughout his career, İlyas Uçar has earned recognition for his dedication to research and education. His scholarly contributions have been acknowledged in scientific circles, with his research findings being cited in academic discussions on embryology and anatomy. His work has not only contributed to medical literature but has also influenced guidelines on drug safety during pregnancy.

As an esteemed faculty member, he has played a pivotal role in shaping the academic curriculum, ensuring that students receive a well-rounded education in anatomical sciences. His ability to inspire and guide young researchers has cemented his reputation as a mentor and leader in his field.

🌍 Impact and Influence

The influence of İlyas Uçar extends beyond the lecture halls and research laboratories. His findings have raised awareness about the importance of cautious pharmaceutical use during pregnancy, prompting further investigations into the long-term effects of medications on fetal development. His work continues to serve as a reference point for medical researchers, policymakers, and healthcare professionals seeking to enhance patient safety.His collaborations with medical institutions and research centers have facilitated knowledge exchange, ensuring that his discoveries have practical implications in clinical and pharmacological settings. By addressing critical questions in developmental anatomy, he has contributed to the broader understanding of how external factors influence human growth and development.

Publication

  • Effect of respiratory muscle training on pulmonary function and aerobic endurance in soccer players
    T. Ozmen, G.Y. Gunes, I. Ucar, H. Dogan, T.U. Gafuroglu – 2017

 

  • The effect of kinesio taping versus stretching techniques on muscle soreness, and flexibility during recovery from Nordic hamstring exercise
    T. Ozmen, G.Y. Gunes, H. Dogan, I. Ucar, M. Willems – 2017

 

  • The relationship between muscle size, obesity, body fat ratio, pain, and disability in individuals with and without nonspecific low back pain
    I. Ucar, C. Kararti, I. CĂŒce, E. Veziroğlu, A. ÖzĂŒdoğru, F.A. Koçak, Y. Dadalı – 2021

 

  • Is scoliosis related to mastication muscle asymmetry and temporomandibular disorders? A cross-sectional study
    I. Ucar, S. Batin, M. Arik, A. Payas, E. Kurtoğlu, C. Kararti, T. Seber, et al. – 2022

 

  • Is the integration problem in the sensorimotor system the cause of adolescent idiopathic scoliosis?
    A. Payas, S. Batin, E. Kurtoğlu, M. Arik, T. Seber, I. Ucar, E. Unur – 2023

 

  • Analysis of changes in brain morphological structure of Taekwondo athletes by diffusion tensor imaging
    E. Kurtoğlu, A. Payas, S. DĂŒz, M. Arik, I. Ucar, T.T. Tokmak, M.F. Erbay, N. Acer, et al. – 2023

 

  • The role of pineal gland volume in the development of scoliosis
    S. Batin, Y. Ekinci, K. GĂŒrbĂŒz, A. Payas, E. Kurtoğlu, I. Ucar, T. Seber, M. Arik, et al. – 2023

 

  • Masseter muscle thickness and elasticity in bruxism after exercise treatment: A comparison trial
    I. Ucar, C. Kararti, Y. Dadali, A. ÖzĂŒdoğru, M. Okçu – 2022

 

  • The potential teratogenic effects of interferon beta-1a and interferon beta-1b on in vitro embryonic development
    I. Ucar, T. Ertekin, M. Nisari, D. Ceylan, Ö. Al, H. Ülger – 2016

 

  • Morphometric evaluation of acetabulum
    G.B. Uzun, M. Değermenci, I. Ucar, A. Arslan, M. Nisari – 2020

🔍 Conclusion

İlyas Uçar’s contributions to anatomical sciences extend beyond theoretical research, making a tangible impact on medical education and drug safety. His investigations into embryonic development have deepened the understanding of teratogenic risks, guiding both researchers and healthcare professionals. With a commitment to advancing knowledge through interdisciplinary collaboration, he continues to shape the future of anatomical and medical research. His legacy lies not only in his scientific discoveries but also in his role as an educator and mentor, ensuring that future generations carry forward his passion for medical science.

 

Rasoul Sabetahd | Systems Neuroscience | Best Researcher Award

Dr. Rasoul Sabetahd | Systems Neuroscience | Best Researcher Award

Dr. Rasoul Sabetahd, Islamic Azad University, Iran.

Dr. Rasoul Sabetahd, a distinguished civil engineer and academic, has dedicated his career to advancing the field of civil engineering through teaching, research, and practical contributions. As a faculty member at the Department of Civil Engineering, Sofian Branch, Islamic Azad University, Iran, he has played a transformative role in fostering innovation, mentoring future engineers, and addressing the pressing challenges of modern infrastructure. His work, rooted in sustainability and resilience, has left a profound impact on academia and the engineering industry alike.

 

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đŸŒ± Early Academic Pursuits

Dr. Rasoul Sabetahd embarked on his academic journey with an enduring passion for civil engineering. He pursued his foundational studies in this field, demonstrating exceptional aptitude and dedication. His formative years were marked by a deep curiosity about structural systems and an eagerness to contribute to the advancement of infrastructure development. These early academic experiences laid the groundwork for his future scholarly achievements.

đŸ—ïž Professional Endeavors

As a prominent member of the Department of Civil Engineering at the Sofian Branch of Islamic Azad University, Iran, Dr. Sabetahd has played a pivotal role in shaping the academic and professional landscape of civil engineering. His career is characterized by a commitment to teaching, mentoring, and equipping students with the practical and theoretical knowledge necessary for addressing modern engineering challenges. He has also collaborated with industry professionals to bridge the gap between academia and practical applications.

📚 Contributions and Research Focus

Dr. Sabetahd’s research has focused on groundbreaking advancements in civil engineering, including sustainable construction techniques, innovative materials, and structural resilience. Through meticulous studies and publications, he has enriched the academic discourse in civil engineering, providing valuable insights that have been widely acknowledged by peers. His work is deeply rooted in addressing contemporary engineering challenges, contributing significantly to the betterment of urban development and infrastructure planning.

🏆 Accolades and Recognition

Dr. Sabetahd’s dedication and expertise have earned him numerous accolades in the field of civil engineering. His research contributions and commitment to education have been recognized at national and international levels, bringing prestige to his institution and inspiring his colleagues and students. These honors reflect his influence as a leader in his domain.

🌍 Impact and Influence

The impact of Dr. Sabetahd’s work extends far beyond academia. His innovations and methodologies have been adopted in various real-world projects, demonstrating their practical value. As a mentor and educator, he has shaped the careers of countless students who now contribute to the field globally. His ability to blend research with practical applications has solidified his reputation as a transformative figure in civil engineering.

🔗 Legacy and Future Contributions

Dr. Sabetahd’s legacy is defined by his unwavering dedication to advancing civil engineering. Looking ahead, he aims to continue contributing to the field through innovative research, fostering new talent, and promoting sustainable engineering practices. His vision for the future involves not only addressing current challenges but also anticipating the needs of future generations.This biography celebrates the remarkable journey of Dr. Rasoul Sabetahd, highlighting his contributions and the lasting impact he has made in civil engineering.

📚 Publications

  1. Development of an Adaptive Chaotic Fuzzy Neural Network Controller for Mitigating Seismic Response in a Structure Equipped with an Active Tuned Mass Damper
    • Authors: Rasoul Sabetahd, Ommegolsoum Jafarzadeh
    • Year: 2025

 

  1. A Multiple Model Type-3 Fuzzy Control for Offshore Wind Turbines Using the Active Rotary Inertia Driver (ARID)
    • Authors: Chunwei Zhang, Meihua Liu, Zhihu Liu, Rasoul Sabetahd, Hamid Taghavifar, Ardashir Mohammadzadeh
    • Year: 2024

 

  1. Design of a Novel Intelligent Adaptive Fractional-Order Proportional-Integral-Derivative Controller for Mitigation of Seismic Vibrations of a Building Equipped with an Active Tuned Mass Damper
    • Authors: Ommegolsoum Jafarzadeh, Rasoul Sabetahd, Seyyed Arash Mousavi Ghasemi, Seyed Mehdi Zahrai
    • Year: 2024

 

  1. Design of an Online Adaptive Fractional-Order Proportional-Integral-Derivative Controller to Reduce the Seismic Response of the 20-Story Benchmark Building Equipped with an Active Control System
    • Authors: Ommegolsoum Jafarzadeh, Seyyed Arash Mousavi Ghasemi, Seyed Mehdi Zahrai, Rasoul Sabetahd, Ardashir Mohammadzadeh, Ramin Vafaei Poursorkhabi, Vasudevan Rajamohan
    • Year: 2024

 

  1. Response Attenuation of a Structure Equipped with ATMD under Seismic Excitations Using Methods of Online Simple Adaptive Controller and Online Adaptive Type-2 Neural-Fuzzy Controller
    • Authors: Rasoul Sabetahd, Seyed Arash Mousavi Ghasemi, Ramin Vafaei Poursorkhabi, Ardashir Mohammadzadeh, Yousef Zandi
    • Year: 2022

 

  1. Evaluation of Pall Friction Damper Performance in Near-Fault Earthquakes by Using Nonlinear Time History Analysis
    • Authors: Jafarzadeh, K., Lotfollahi-Yaghin, M.A., Sabetahd, R.
    • Year: 2012

 

Conclusion

Dr. Sabetahd’s journey exemplifies the fusion of academic excellence, professional dedication, and impactful research. Through his efforts, he has not only contributed to the growth of civil engineering but also inspired a new generation of engineers to pursue excellence. His legacy, defined by a commitment to progress and innovation, ensures his enduring influence in the field. As he continues his work, Dr. Sabetahd remains a beacon of inspiration, shaping the future of civil engineering.