Mustafa Nazıroğlu | Cellular Neuroscience | Neuroscience Research Excellence Award

Prof. Mustafa Nazıroğlu | Cellular Neuroscience | Neuroscience Research Excellence Award

Prof. Mustafa Nazıroğlu,  Suleyman Demirel University, Turkey.

Professor Mustafa Nazıroğlu is a distinguished scholar with dual doctorates in Physiology and Neuroscience. Beginning his academic journey at Fırat University and advancing to leadership roles at Süleyman Demirel University, he has become a global authority in the fields of oxidative stress, calcium signaling, and TRP ion channels. His research portfolio includes over 270 peer-reviewed articles and thousands of citations, showcasing a profound impact on cellular neuroscience. Beyond research, he has led major international congresses, served on editorial boards of top journals, and has been honored with numerous awards and fellowships in Europe, Asia, and North America.

Profile

Orcid

 

🎓 Early Academic Pursuits

Professor Mustafa Nazıroğlu embarked on his academic journey with a degree from the Faculty of Veterinary Medicine at Fırat University in 1991. Driven by a profound curiosity for physiological mechanisms, he pursued a Ph.D. in Physiology at the same institution, which he completed between 1992 and 1996. His academic ambitions later led him to earn a second Ph.D. in Neuroscience from Süleyman Demirel University (SDU) in 2018, reflecting his commitment to interdisciplinary scholarship and continuous learning.

🧠 Professional Endeavors in Neuroscience and Biophysics

Currently, Professor Nazıroğlu holds the position of Head of the Department of Biophysics and Neuroscience at SDU Medical Faculty. His professional path has been shaped by a deep dedication to academic leadership, having served in several key roles including department head, director of the Neuroscience Research Centre (NOROBAM), and chair of numerous international scientific congresses. Notably, he has successfully organized the biennial International World Congress of Oxidative Stress, Calcium Signalling and TRP Channels from 2006 to 2020, as well as the International Brain Research School series from 2015 to 2024. His influence has also reached global platforms, including service on the organizing committee for the TEMA-14 Congress in Hubei, China, in 2011.

🔬 Contributions and Research Focus

A prolific researcher, Professor Nazıroğlu has significantly advanced our understanding of oxidative stress, calcium signaling, apoptosis, and ion channel (TRP) physiology. His scientific output includes 274 international research articles, 19 review papers, and six book chapters, collectively amassing over 11,500 citations and earning him a Scopus h-index of 59. He has also contributed as an editorial and reviewing member for leading journals such as Biological Trace Element Research, Scientific Reports (Nature Publishing), Frontiers in Physiology, and Current Neuropharmacology, among others. His research has bridged cellular neuroscience with therapeutic strategies, making him a vital contributor to the global scientific discourse.

🏅 Accolades and Recognition

Throughout his career, Professor Nazıroğlu has received numerous national and international honors, celebrating his scientific achievements and global engagement. These include the NATO Research Fellowship (Germany), the Alexander von Humboldt Fellowship (Germany), and the Young Investigative Scientist Award (USA). He has also been recognized by the Turkish Scientific and Technological Research Council (TÜBİTAK), the Howard Hughes Medical Institute (USA), and was the recipient of the prestigious Khwarizmi International Award (Iran). His visiting professorships at institutions in the UK, Qatar, and Japan further underscore his international reputation and collaboration.

🌍 Impact and Influence

Professor Nazıroğlu’s impact extends beyond academic publishing and conference organization. As a mentor, speaker, and panel member, he has shaped the careers of young neuroscientists and fostered a collaborative global network of researchers in calcium signaling and oxidative biology. His participation in expert advisory boards and scientific panels illustrates the depth of his influence on both research policy and biomedical innovation.

📘 Legacy of Knowledge

With over three decades dedicated to science and education, Professor Nazıroğlu has built a lasting legacy grounded in scientific rigor and visionary leadership. His conferences and educational programs, especially the International Brain Research School, have become cornerstone events for knowledge exchange in neuroscience. He has laid a strong foundation for future advancements in TRP channel research and neurophysiology.

🚀 Future Contributions and Vision

Looking forward, Professor Nazıroğlu continues to guide critical research on cellular responses to oxidative stress and ion channel modulation. His forward-thinking approach, combined with an inclusive scientific philosophy, ensures that he remains a leading voice in shaping the next era of biomedical research. With ongoing collaborative projects and mentorship of emerging scholars, his work is poised to influence both clinical and theoretical frontiers for years to come.

Publication

 

  • Title: Vitamin D Supplementation Modulates Blood and Tissue Zinc, Liver Glutathione and Blood Biochemical Parameters in Diabetic Rats on a Zinc-Deficient Diet
    Authors: Kechrid, Z.; Hamdiken, M.; Nazıroğlu, M.; Flores-Arce, M.
    Year: 2023

 

  • Title: Low molecular weight heparin treatment reduced apoptosis and oxidative cytotoxicity in the thrombocytes of patients with recurrent pregnancy loss and thrombophilia: Involvements of TRPM2 and TRPV1 channels
    Authors: Dal, Y.; Nazıroğlu, M.; Özkaya, M.O.
    Year: 2023

 

  • Title: NMDA Receptor Activation Stimulates Hypoxia-Induced TRPM2 Channel Activation, Mitochondrial Oxidative Stress, and Apoptosis in Neuronal Cell Line: Modular Role of Memantine
    Authors: Kenan Yıldızhan; Mustafa Nazıroğlu
    Year: 2023

 

  • Title: Honey bee venom melittin increases the oxidant activity of cisplatin and kills human glioblastoma cells by stimulating the TRPM2 channel
    Authors: Kemal Ertilav; Mustafa Nazıroğlu
    Year: 2023

 

  • Title: Silver nanoparticles potentiate antitumor and oxidant actions of cisplatin via the stimulation of TRPM2 channel in glioblastoma tumor cells
    Authors: Yener Akyuva; Mustafa Nazıroğlu
    Year: 2023

 

  • Title: A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol
    Author: Nazıroğlu, M.
    Year: 2022

 

  • Title: Amantadine Attenuated Hypoxia-Induced Mitochondrial Oxidative Neurotoxicity, Apoptosis, and Inflammation via the Inhibition of TRPM2 and TRPV4 Channels
    Authors: Öcal, Ö.; Coşar, A.; Nazıroğlu, M.
    Year: 2022

 

  • Title: Eicosapentaenoic acid enhanced apoptotic and oxidant effects of cisplatin via activation of TRPM2 channel in brain tumor cells
    Authors: Öcal, Ö.; Nazıroğlu, M.
    Year: 2022

 

  • Title: Paclitaxel Promotes Oxidative Stress–Mediated Human Laryngeal Squamous Tumor Cell Death through the Stimulation of Calcium and Zinc Signaling Pathways: No Synergic Action of Melatonin
    Authors: Kumbul, Y.Ç.; Nazıroğlu, M.
    Year: 2022

 

  • Title: Protective role of selenium on MPP⁺ and homocysteine-induced TRPM2 channel activation in SH-SY5Y cells
    Authors: Yıldızhan, K.; Nazıroğlu, M.
    Year: 2022

 

🧾 Conclusion

Through an outstanding blend of academic excellence, innovative research, and global collaboration, Professor Nazıroğlu has carved a legacy as a leading figure in neuroscience and biophysics. His efforts in organizing international platforms and mentoring young scientists reflect a career committed to advancing knowledge and fostering global scientific networks. With continued contributions and visionary leadership, he remains a driving force in shaping the future of cellular neurophysiology and therapeutic discovery.

Handrean Soran | Clinical Neuroscience | Best Researcher Award

Prof. Handrean Soran | Clinical Neuroscience | Best Researcher Award

Prof. Handrean Soran,  Manchester University NHS Foundation Trust, United Kingdom.

Dr. Handrean Soran is a distinguished British endocrinologist and researcher with expertise in diabetes, endocrinology, and cardiovascular diseases. His academic journey began in Iraq and advanced through the UK, where he earned prestigious medical qualifications, including an MD in Medicine and MSc in Diabetes and Endocrinology. Throughout his career, Dr. Soran has contributed significantly to research on the relationship between diabetes and cardiovascular health, publishing extensively in high-impact journals like The New England Journal of Medicine and Lancet. His work has garnered global recognition, including an H-index of 49 and numerous accolades, solidifying his position as a leader in his field.

Profile

Google Scholar

 

Early Academic Pursuits 📚

Handrean Soran’s academic journey began in the Kurdistan region of Iraq, where he completed his A-levels with an impressive score of 94.5% from Sulemani High School in 1985. His drive for knowledge led him to pursue his MBChB at Al-Mustansyria University in Baghdad, Iraq, graduating in 1990. This foundational education set the stage for a career dedicated to medical research and practice. After completing his medical degree, he pursued further specialized training in the UK, where he earned his MRCP from the Royal College of Physicians in Edinburgh in 1999, and later, an MSc in Diabetes and Endocrinology from the University of Liverpool in 2006. These early academic milestones laid the foundation for his later expertise in endocrinology and diabetes, fields that would define his career.

Professional Endeavors 🏥

Dr. Handrean Soran’s professional journey is marked by a dedication to medicine, particularly in the fields of endocrinology and diabetes. He has held significant roles in prestigious institutions, with his current position in the Department of Diabetes, Endocrinology, and Metabolism at Manchester University Hospitals NHS Foundation Trust. His medical career was further enhanced by his qualifications as a Fellow of the Royal College of Physicians (FRCP) from both Glasgow and Edinburgh. Throughout his career, Dr. Soran has worked on developing innovative approaches in clinical care and research, constantly striving to improve patient outcomes and advancing medical knowledge.

Contributions and Research Focus 🔬

Dr. Soran’s research focus primarily centers on diabetes, endocrinology, and cardiovascular health, specifically the interplay between metabolic disorders and heart disease. His research efforts have been integral to understanding the link between diabetes and cardiovascular risk, with a significant body of work examining the effects of treatments on these interconnected conditions. His contributions have been recognized through multiple high-impact publications in renowned journals such as the New England Journal of Medicine, Lancet, and European Heart Journal. With an H-index of 49 and over 130 citations, Dr. Soran’s work continues to shape the clinical landscape in these areas, driving further advancements in treatment protocols and therapeutic strategies for diabetes and cardiovascular diseases.

Accolades and Recognition 🏆

Dr. Soran’s career has been decorated with numerous accolades, affirming his status as a leader in his field. He achieved the prestigious title of Fellow of the Royal College of Physicians (FRCP) in both Edinburgh and Glasgow, a testament to his clinical expertise and contribution to medical science. His groundbreaking work in diabetes and cardiovascular research has earned him recognition not only from peers but also from major medical institutions. His publications in top-tier journals further highlight his academic prowess, solidifying his position as a key thought leader in the medical and academic communities.

Impact and Influence 🌍

Dr. Handrean Soran’s work extends beyond the realm of research publications; it has made a lasting impact on the clinical management of diabetes and cardiovascular diseases worldwide. His insights have contributed to shaping healthcare policies and clinical practices, particularly in the management of diabetic patients at high cardiovascular risk. Through his collaboration with the Division of Cardiovascular Sciences at the University of Manchester, he has fostered interdisciplinary approaches to solving complex medical challenges, advancing the integration of cardiovascular care with endocrinology. His work has influenced not only academic circles but also clinical practice, providing new directions for patient care.

Legacy and Future Contributions 🌱

As Dr. Soran continues his impactful work, his legacy is one of dedication to improving patient health outcomes and advancing the fields of endocrinology and diabetes. With a deep commitment to teaching and mentorship, Dr. Soran plays a pivotal role in training the next generation of doctors and researchers. His future contributions are poised to further explore the intricate relationship between metabolic disorders and cardiovascular health, addressing the growing global burden of these interconnected diseases. His work will undoubtedly continue to guide both clinical practice and future research in endocrinology, diabetes, and cardiovascular medicine, ensuring his ongoing influence in these critical areas.

Global Recognition and Influence 🌐

Dr. Soran’s influence reaches across borders, as evidenced by his extensive publication record and recognition within the global medical community. His research has not only enriched the scientific literature but also contributed to global health initiatives, particularly in the area of metabolic disorders and cardiovascular diseases. With collaborations spanning multiple continents, Dr. Soran is dedicated to improving health outcomes globally, offering expert insights into the prevention and management of diabetes and heart disease. His role in shaping clinical guidelines and his participation in international research collaborations further amplify his global impact.

Academic and Professional Leadership 🎓

In addition to his research contributions, Dr. Soran’s leadership within academia is profound. He holds multiple academic positions, including his affiliation with the University of Manchester, where he plays an integral role in advancing research within the Division of Cardiovascular Sciences. His leadership extends to mentoring young researchers and clinicians, helping to foster a new generation of experts in endocrinology and diabetes. Dr. Soran’s academic vision continues to drive progress in both education and research, making significant strides in improving how diabetes and cardiovascular diseases are understood and treated. His future work promises to leave a lasting mark on medical education and the advancement of scientific knowledge.

Publication

  • Cardiovascular efficacy and safety of bococizumab in high-risk patients
    Author: PM Ridker
    Year: 2017

 

  • Volanesorsen and triglyceride levels in familial chylomicronemia syndrome
    Author: JL Witztum
    Year: 2019

 

  • Triglyceride lowering with pemafibrate to reduce cardiovascular risk
    Author: A Das Pradhan
    Year: 2022

 

  • Diabetes dyslipidemia
    Author: JD Schofield
    Year: 2016

 

  • Lysosomal acid lipase deficiency–an under-recognized cause of dyslipidaemia and liver dysfunction
    Author: Ž Reiner
    Year: 2014

 

  • Obesity: a critical risk factor in the COVID‐19 pandemic
    Author: S Kwok
    Year: 2020

 

  • Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY …
    Author: KK Ray
    Year: 2019

 

  • Hypercholesterolaemia and its management
    Author: D Bhatnagar
    Year: 2008

 

  • Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies
    Author: B Williams
    Year: 2018

 

  • Long-term treatment with evolocumab added to conventional drug therapy, with or without apheresis, in patients with homozygous familial hypercholesterolaemia: an interim subset …
    Author: FJ Raal
    Year: 2017

 

Conclusion

Dr. Handrean Soran’s career is marked by profound contributions to medical science, particularly in the fields of diabetes and cardiovascular health. His groundbreaking research and clinical expertise have had a significant impact on both academic and healthcare practices worldwide. As a recognized leader in his field, Dr. Soran’s work continues to influence the management of metabolic and cardiovascular diseases, and his future contributions promise to further advance these critical areas of medical research and practice. His legacy is one of dedication, leadership, and a commitment to improving health outcomes globally.