Toru Yoshiura | Clinical Neuroscience | Neuroscience Research Excellence Award

Posted on by Neuroscientists

Dr. Toru Yoshiura | Clinical Neuroscience | Neuroscience Research Excellence Award

Dr. Toru Yoshiura,  National Defense Medical College, Japan.

Dr. Toru Yoshiura, a Lieutenant Commander in the Japan Maritime Self-Defense Force (JMSDF) and a board-certified neurosurgeon, has cultivated a remarkable career blending military service, clinical excellence, and academic research. A graduate of the National Defense Medical College, he has pursued specialized training in diving medicine and neuroendoscopic surgery while serving in key clinical and field deployments, including anti-piracy missions. His research focuses on innovative neuroprotective strategies for subarachnoid hemorrhage, and he actively contributes to the education of future neurosurgeons through specialized anatomical dissection courses. Dr. Yoshiura holds multiple national certifications and is an active member of prominent neurosurgical societies, where he plays a leadership role in advancing young professionals.

Profile

Orcid

🎓 Early Academic Pursuits

Born on January 15, 1987, in Hiroshima, Japan, Dr. Toru Yoshiura began his distinguished journey in medicine with a solid academic foundation at the National Defense Medical College, where he pursued his studies from April 2005 to March 2011. During these formative years, he developed a strong inclination toward the intricate world of neurosurgery. His academic journey was not limited to conventional study; he also completed rigorous military medical training at the JMSDF Officer Candidate School in 2011 and the Diving Medical Officer’s Course in 2013. Driven by both curiosity and commitment, Dr. Yoshiura later pursued graduate studies in medicine at the same institution, where he currently investigates novel therapeutic strategies in neurosurgical conditions, particularly focusing on cerebral ischemia models.

⚓ Professional Endeavors

Dr. Yoshiura’s career seamlessly blends clinical excellence with military service. Since 2011, he has been a commissioned officer in the Japan Maritime Self-Defense Force (JMSDF), rising to the rank of Lieutenant Commander. His professional journey commenced with a clinical residency at the National Defense Medical College Hospital, followed by a tenure as a neurosurgeon at JSDF Yokosuka Hospital, where he also took part in the 17th Deployment Surface Force Counter Piracy Enforcement in 2013–2014. Subsequent assignments included advanced clinical residency, service at the JSDF Central Hospital, and another deployment during the 37th Counter Piracy Enforcement (2020–2021). Currently, he practices at the National Defense Medical College Hospital, where he brings both his clinical and research expertise to the forefront.

🧠 Contributions and Research Focus

Dr. Yoshiura has emerged as a dedicated researcher with a keen interest in neuroprotection and neurovascular recovery. His ongoing doctoral research explores the synergistic effects of hydrogen inhalation and intrathecal magnesium sulfate treatment in enhancing ischemic outcomes without suppressing cortical spreading depolarization—work that promises to revolutionize the management of subarachnoid hemorrhage (SAH). Moreover, he serves as the Course Director of the White Matter Dissection Course, a specialized program aimed at enhancing neurosurgical anatomical understanding, further showcasing his commitment to academic mentorship and the future of neurosurgical training.

🏅 Accolades and Recognition

Dr. Yoshiura’s dedication to excellence has been officially recognized through multiple prestigious medical certifications in Japan. He holds certifications from the Japanese Boards of Neurosurgery, Stroke, Neuroendovascular Therapy, and Neurotraumatology, and he is also a qualified Neuroendoscopic Surgeon. His credentials reflect a consistent track record of advanced surgical training and expertise across a spectrum of subspecialties, reinforcing his status as a versatile and trusted neurosurgeon in both military and civilian healthcare settings.

🌐 Impact and Influence

Beyond operating rooms and laboratories, Dr. Yoshiura has made meaningful contributions to the broader medical and scientific community through active engagement with multiple professional organizations. He is a core member of the Under 40 Committee of the Japanese Congress for Brain Tumor Surgery, signifying his leadership among emerging neurosurgeons. His involvement spans a wide array of societies, including the Japan Neurosurgical Society, Japanese Society on Surgery for Cerebral Stroke, and Japan Society for Neuro-Oncology, among others. This multi-society participation not only amplifies his influence but also allows him to remain at the cutting edge of developments in neurosurgical practice and policy.

🌍 Service Beyond Borders

Dr. Yoshiura’s compassion and sense of duty extend beyond his professional obligations. In 2010, he volunteered at a kindergarten in Bari, Indonesia, demonstrating his humanitarian spirit and willingness to serve communities in need. This formative experience abroad may have enriched his global outlook on medicine and underscored the human side of healthcare—a trait that continues to inform his interactions with patients and peers alike.

🚀 Legacy and Future Contributions

As a rising leader in neurosurgery within the military-medical sphere, Dr. Yoshiura’s legacy is already being defined by a synthesis of cutting-edge research, exceptional surgical practice, and dedicated mentorship. With his ongoing doctoral work poised to make significant contributions to the treatment of ischemic brain injuries, and his involvement in advanced neurosurgical education, he is set to influence both clinical practices and the next generation of neurosurgeons. His unique integration of military precision and academic rigor ensures that his future contributions will be both impactful and enduring.

Publication

  1. Title: Carotid Endarterectomy with Twisted Internal Jugular Vein Located Anterior to the Common Carotid Artery
    Authors: Arumu Endo, Terushige Toyooka, Kazuya Fujii, Satoru Takeuchi, Toru Yoshiura, Masaya Nakagawa, Yohei Otsuka, Arata Tomiyama, Kojiro Wada
    Year: 2025

 

  1. Title: Effectiveness of Keyhole Clipping of Unruptured Intracranial Aneurysms Detected by “Brain Dock” in Healthy Japanese Adults
    Authors: Toru Yoshiura, Satoru Takeuchi, Terushige Toyooka, Arata Tomiyama, Kojiro Wada, Yasuaki Nakao, Takuji Yamamoto, Kentaro Mori, toruyukiko
    Year: 2023

 

  1. Title: KLC1-ROS1 Fusion Exerts Oncogenic Properties of Glioma Cells via Specific Activation of JAK-STAT Pathway
    Authors: Takashi Fujii, Yoshiko Nakano, Daichi Hagita, Nobuyuki Onishi, Arumu Endo, Masaya Nakagawa, Toru Yoshiura, Yohei Otsuka, Satoru Takeuchi, Mario Suzuki et al.
    Year: 2023

 

  1. Title: Surgical Rescue Technique for Incomplete Burr Hole Using a Small Bone Piece and the Craniotome
    Authors: Toru Yoshiura, Kojiro Wada, Kosuke Kumagai, Satoru Takeuchi, Terushige Toyooka, Otani, Kentaro Mori
    Year: 2019

🔚 Conclusion

Dr. Yoshiura’s journey exemplifies a rare integration of surgical mastery, military discipline, and scientific innovation. His commitment to advancing the field of neurosurgery—through both cutting-edge research and hands-on mentorship—positions him as a future leader in academic and military medicine alike. With a career rooted in service, science, and skill, Dr. Yoshiura is not only shaping current practices but also building a lasting legacy for future generations of neurosurgeons in Japan and beyond.

Che Ping Cheng | Translational Neuroscience | Best Researcher Award

Posted on by Neuroscientists

Prof. Che Ping Cheng | Translational Neuroscience | Best Researcher Award

Prof. Che Ping Cheng, Wake Forest University School of Medicine, United States.

Dr. Che Ping Cheng, M.D., Ph.D., FAHA, is a distinguished cardiovascular physiologist and internal medicine specialist whose career has been dedicated to advancing the understanding of heart function and failure. From earning his medical degree in China to completing a Ph.D. in Physiology at Wayne State University, and later conducting pivotal postdoctoral research at Wake Forest School of Medicine, Dr. Cheng has consistently pursued excellence in science and education. His research on ventricular mechanics, volume loading, and heart failure has significantly influenced both experimental cardiology and clinical practice. Recognized as a Fellow of the American Heart Association, he is also a dedicated mentor, shaping the next generation of cardiovascular researchers through his academic leadership.

Profile

Scopus

 

🎓 Early Academic Pursuits

Dr. Che Ping Cheng’s journey into medicine and science began in Nanjing, China, where he earned his M.D. degree from Nanjing Railway Medical University in 1977. His early academic path reflected a deep interest in understanding the intricacies of human health, particularly in cardiovascular physiology. Driven by a desire to expand his knowledge and research capabilities, Dr. Cheng pursued his Ph.D. in Physiology at Wayne State University School of Medicine in Detroit, Michigan, completing his degree in 1986. Under the mentorship of Dr. Robert S. Shepard, his doctoral work focused on exploring the mechanisms of cardiovascular response to volume loading in a canine model with tricuspid valvulectomy, setting a strong foundation for his lifelong focus on heart function and disease mechanisms.

🩺 Professional Endeavors

Following his academic training, Dr. Cheng embarked on postdoctoral studies at the Bowman Gray School of Medicine (now part of Wake Forest School of Medicine), where he continued to cultivate his expertise in internal medicine and cardiovascular physiology. Between 1986 and 1988, he served as a Postdoctoral Fellow under the guidance of Dr. William C. Little. His research during this period focused on ventricular dynamics and the physiological factors affecting active ventricular filling, which would later inform his broader work on heart failure and cardiac function. Dr. Cheng has since remained at Wake Forest School of Medicine, where he is currently a distinguished member of the Section on Cardiovascular Medicine.

🧪 Contributions and Research Focus

Dr. Cheng’s career has been characterized by a deep commitment to advancing the understanding of cardiac hemodynamics, ventricular interaction, and heart failure mechanisms. His research has explored how ventricular function responds under altered physiological states, and how these responses inform disease progression and treatment strategies. His early animal model studies have provided critical insights into the interplay between structural and functional changes in the heart, especially in the context of diastolic dysfunction and volume overload conditions. Dr. Cheng has also made significant strides in translating these findings to clinical contexts, influencing how cardiologists approach diagnosis and therapy.

🏅 Accolades and Recognition

Throughout his career, Dr. Cheng has received considerable recognition for his scholarly contributions. He is a Fellow of the American Heart Association (FAHA), an honor that reflects his standing in the field of cardiovascular research and his commitment to scientific excellence. His work has earned the respect of colleagues and institutions alike, leading to numerous invitations to contribute to collaborative projects, serve on peer-review panels, and mentor future generations of cardiovascular researchers.

🌍 Impact and Influence

Dr. Cheng’s work has had a lasting impact on both experimental and clinical cardiology. By elucidating the mechanistic basis of ventricular dysfunction, he has helped shift paradigms in heart failure management, particularly in the areas of ventricular interdependence and preload responsiveness. His research findings are frequently cited in textbooks and high-impact journals, and they continue to inform guidelines for cardiac care and interventions. Through his work at Wake Forest and beyond, Dr. Cheng has played a pivotal role in bridging laboratory discoveries with bedside applications.

👨‍🏫 Legacy and Mentorship

As a respected mentor and educator, Dr. Cheng has dedicated a significant portion of his career to training medical students, residents, and postdoctoral fellows. His mentorship has influenced numerous emerging scholars in cardiovascular medicine, many of whom have gone on to successful academic and clinical careers. His guidance combines a rigorous scientific approach with a deep sense of responsibility to patient care and scientific integrity, shaping a legacy that extends well beyond his own research output.

🔬 Future Contributions and Vision

Looking ahead, Dr. Cheng remains committed to the advancement of cardiovascular research, with a continued focus on uncovering the cellular and mechanical determinants of heart disease. His vision includes fostering collaborative projects that integrate biomedical engineering, imaging, and computational modeling to further understand cardiac performance. With decades of experience and a forward-thinking approach, Dr. Cheng’s future contributions are poised to leave a lasting mark on the field of translational cardiovascular medicine.

Publication

  1. Title: Increased CaMKII activation and contrast changes of cardiac β1-and β3-Adrenergic signaling pathways in a humanized angiotensinogen model of hypertension
    Authors: Sun, Xiaoqiang; Cao, Jing; Chen, Zhe; Ferrario, Carlos M.; Cheng, Cheping
    Year: 2023
    Journal: Heliyon

 

  1. Title: Calmodulin-dependent protein kinase II activation promotes kidney mesangial expansion in streptozotocin-induced diabetic mice
    Authors: Mikhailov, Alexei V.; Liu, Yixi; Cheng, Hengjie; Lin, Jen Jar; Cheng, Cheping
    Year: 2022
    Journal: Heliyon

 

  1. Title: Chronic GPR30 agonist therapy causes restoration of normal cardiac functional performance in a male mouse model of progressive heart failure: Insights into cellular mechanisms
    Authors: Zhang, Xiaowei; Li, Tiankai; Cheng, Hengjie; Groban, Leanne; Cheng, Cheping
    Year: 2021
    Journal: Life Sciences

 

  1. Title: Chronic Ca2+/calmodulin-dependent protein Kinase II inhibition rescues advanced heart failure
    Authors: Liu, Yixi; Shao, Qun; Cheng, Hengjie; Zhao, David Xiao Ming; Cheng, Cheping
    Year: 2021
    Journal: Journal of Pharmacology and Experimental Therapeutics

 

  1. Title: The Angiotensin-(1–12)/Chymase axis as an alternate component of the tissue renin angiotensin system
    Authors: Ferrario, Carlos M.; Groban, Leanne; Wang, Hao; Sun, Xuming; Ahmad, Sarfaraz
    Year: 2021
    Journal: Molecular and Cellular Endocrinology

 

  1. Title: Reversal of angiotensin-(1–12)-caused positive modulation on left ventricular contractile performance in heart failure: Assessment by pressure-volume analysis
    Authors: Li, Tiankai; Zhang, Zhi; Zhang, Xiaowei; Ferrario, Carlos M.; Cheng, Cheping
    Year: 2020
    Journal: International Journal of Cardiology

 

  1. Title: Female Heart Health: Is GPER the Missing Link?
    Authors: Groban, Leanne; Tran, Q. K.; Ferrario, Carlos M.; Wang, Hao; Lindsey, Sarah H.
    Year: (Not specified, but likely 2020 or 2021)
    Journal: (Not specified)

 

🏁 Conclusion

Dr. Cheng’s legacy is one of intellectual rigor, clinical relevance, and mentorship. His work has not only deepened the scientific understanding of cardiac physiology but has also shaped modern approaches to diagnosing and managing heart failure. With a career spanning continents and disciplines, Dr. Cheng continues to be a guiding force in cardiovascular medicine, and his future contributions are anticipated to further advance the frontiers of heart research and patient care.

 

Rong Wang | Oncology | Best Researcher Award

Posted on by Neuroscientists

Dr. Rong Wang | Oncology | Best Researcher Award

Dr. Rong Wang, Nanfang Hospital, Southern Medical University, China.

Dr. Rong Wang, a distinguished figure at Nanfang Hospital, Southern Medical University, has built an impressive career that bridges clinical excellence and pioneering research. From her early academic days, she showed a strong commitment to medical science, which translated into impactful professional endeavors in both patient care and research. Her primary focus lies in clinical and translational medicine, where she has made significant contributions through innovative diagnostics, treatment strategies, and interdisciplinary collaboration. Her accolades reflect her dedication, while her influence is evident in the global reach of her work and her role as a mentor and leader in the medical community.

Profile

Orcid

 

🎓 Early Academic Pursuits

Dr. Rong Wang began her academic journey with a strong foundation in medical sciences, reflecting a deep commitment to healthcare from an early stage. Her educational path was marked by excellence, as she pursued rigorous training in clinical medicine and specialized disciplines. Her formative years at esteemed institutions prepared her with a robust understanding of both theoretical and practical dimensions of medical research, setting the stage for a remarkable professional trajectory.

🏥 Professional Endeavors

Currently affiliated with Nanfang Hospital at Southern Medical University, China, Dr. Rong Wang has established herself as a dedicated clinician and researcher. Her work seamlessly integrates patient care with academic inquiry, creating a dynamic synergy between hospital-based practice and medical innovation. Her role at this prestigious institution has enabled her to engage in cutting-edge research, medical education, and multidisciplinary collaborations that enhance both her personal growth and the advancement of the medical field.

🔬 Contributions and Research Focus

Dr. Wang’s research interests are deeply embedded in clinical and translational medicine, particularly focusing on emerging healthcare challenges in China and globally. Her investigations often revolve around innovative diagnostic techniques, treatment protocols, and patient-centered care strategies. With a vision to bridge the gap between laboratory research and bedside application, her contributions have not only enriched scientific literature but also improved therapeutic outcomes.

🏅 Accolades and Recognition

Over the years, Dr. Rong Wang has been the recipient of numerous accolades that reflect her unwavering dedication to medicine and research. Her work has garnered respect from peers and institutions alike, earning her prestigious awards and invitations to speak at national and international conferences. These honors underscore her role as a thought leader and innovator in the field.

🌏 Impact and Influence

Dr. Wang’s influence extends beyond the walls of her hospital. Her research has informed public health policies and contributed to global discourses on health equity and innovation. She actively collaborates with other researchers and healthcare professionals to promote knowledge exchange, medical training, and sustainable healthcare models. Her mentorship has inspired a new generation of researchers and medical practitioners who are carrying forward her legacy of excellence and empathy.

🌟 Legacy and Future Contributions

As she continues to evolve in her career, Dr. Rong Wang remains committed to pioneering research and medical advancement. Her future aspirations include expanding her research on integrative healthcare solutions and influencing healthcare reform through evidence-based policies. Through her persistent efforts, she aims to leave a lasting legacy marked by innovation, compassion, and societal impact.

🧠 Research-Driven Innovation

At the core of Dr. Wang’s professional identity is her relentless pursuit of scientific truth and practical solutions. Her research embodies a spirit of curiosity and a drive to solve complex medical challenges. Whether through publishing in high-impact journals or leading clinical trials, she consistently pushes the boundaries of knowledge, aiming to bring transformative change to patient care and health systems.

publication

  • Title: Establishment and Characterization of a Brain Parenchymal Metastatic Cell Line AlmoR1 Derived From an NSCLC Patient With EGFR‐TKI Resistance
    Authors: Jingyi Wu, Xiangfei Wu, Jing Wang, Guili Feng, Yuhan Wang, Zide Chen, Wei Wang, Rong Wang
    Year: 2025

 

  • Title: Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer
    Authors: Rong Wang, Tadaaki Yamada, Kenji Kita, Hirokazu Taniguchi, Sachiko Arai, Koji Fukuda, Minoru Terashima, Akihiko Ishimura, Akihiro Nishiyama, Azusa Tanimoto, et al.
    Year: 2020

 

🔚 Conclusion

With a future-oriented mindset and an unwavering commitment to advancing healthcare, Dr. Rong Wang stands as a beacon of medical innovation and compassion. Her career is a testament to how scientific research and clinical practice can come together to improve lives and shape the future of medicine. As she continues her journey, her legacy will be defined by her transformative contributions, the people she has inspired, and the advancements she has helped bring to life in the world of healthcare.

Lin Jizhen | Cancer immunotherapy | Best Researcher Award

Posted on by Neuroscientists

Prof. Lin Jizhen | Cancer immunotherapy | Best Researcher Award

Prof.  Lin Jizhen, Union Hospital, Fujian Medical University, China.

Dr. Jizhen Lin is a distinguished physician-scientist whose career has been defined by an unwavering dedication to the field of auditory molecular biology. With his foundational medical education from Fujian Medical University and advanced research training in biochemistry and molecular biology at the University of Minnesota, he has seamlessly blended clinical acumen with scientific innovation. His professional roles have evolved from intern and research fellow to Associate Professor and Laboratory Director, reflecting a career rich in mentorship, discovery, and leadership. His research has focused extensively on otitis media and the molecular mechanisms of hearing, contributing valuable insights into the pathophysiology and potential treatments of auditory disorders.

Profile

Scopus

 

📚 Early Academic Pursuits

Dr. Jizhen Lin’s academic journey began with a strong foundation in medicine at Fujian Medical University, Fuzhou, China, where he earned his M.D. in 1982 and an M.S. in Otolaryngology in 1987. His thirst for advanced knowledge and scientific discovery later brought him to the University of Minnesota, Minneapolis, where he immersed himself in the fields of biochemistry and molecular biology, further enriching his expertise and setting the stage for a robust research career in auditory sciences.

🧪 Professional Endeavors

Dr. Lin’s professional path has been marked by consistent dedication and a progressive climb through academic and research positions. His early clinical exposure as an intern at Union Hospital in Fujian laid the groundwork for his subsequent transition into research. Between 1992 and 1995, he served as an International Research Fellow at the Otitis Media Research Center (OMRC), University of Minnesota. He continued to make strides as a Research Scientist and Co-director of the Otopathology-Molecular Biology Laboratory, contributing significantly to auditory molecular biology. His leadership abilities culminated in his appointment as Director of the Auditory Molecular Biology Laboratory, and he has been serving as an Associate Professor in the Department of Otolaryngology at the University of Minnesota Medical School since 2008.

🔬 Contributions and Research Focus

Throughout his career, Dr. Lin has concentrated on unraveling the complexities of auditory molecular biology with a primary focus on otitis media, a prevalent childhood disease. His contributions have been instrumental in bridging clinical otolaryngology with molecular science, employing biochemical tools to investigate the pathogenesis of auditory disorders. His laboratory has played a critical role in advancing understanding of the genetic and cellular mechanisms that underpin hearing loss and middle ear infections, particularly through innovative translational approaches.

🏅 Accolades and Recognition

Dr. Lin’s relentless pursuit of scientific excellence and impactful research has earned him widespread recognition in the field of otolaryngology. His tenure as a Graduate Faculty advisor reflects not only his dedication to mentorship but also the high regard his peers and the academic community have for his expertise. While he may not be adorned with numerous public awards, the esteem in which he is held by colleagues and students alike underscores the quiet yet profound impact of his scholarly work.

🌍 Impact and Influence

The influence of Dr. Lin’s research extends beyond the laboratory, as his findings have contributed meaningfully to clinical practices and therapeutic approaches in otolaryngology. By identifying key molecular targets and pathways involved in auditory disorders, his work continues to shape the development of novel diagnostics and treatments. Furthermore, his role in international research collaborations underscores his commitment to knowledge exchange and global scientific advancement.

🧠 Legacy and Future Contributions

Dr. Lin’s legacy is firmly rooted in the integration of molecular science with clinical otolaryngology, a field he has helped shape through decades of dedicated research and academic mentorship. As a mentor to future scientists and a contributor to critical advancements in auditory health, he remains a cornerstone in the bridge between basic science and patient care. Looking forward, his ongoing work in auditory molecular biology is poised to further uncover the mechanisms of hearing and hearing loss, promising new frontiers in medical intervention and auditory health.

🧬 Lifelong Commitment to Hearing Science

Dr. Lin’s career embodies a lifelong commitment to auditory science, from the clinic to the lab. His seamless blend of clinical knowledge, molecular expertise, and research leadership has fostered a rich legacy in otolaryngology. With ongoing contributions to scientific understanding and future discoveries on the horizon, Dr. Lin continues to inspire a generation of researchers and clinicians dedicated to improving hearing health worldwide.

Publication

  1. Title: Cell-free transcription amplification-based split-type electrochemical sensor using enzyme-linked magnetic microbeads for minimal residual leukemia detection
    Authors: Luying Yu, Jinyuan Chen, Huanjiao Weng, … Xinhua Lin, Guangxian Zhong
    Year: 2025

 

  1. Title: Antibody screening-assisted multichannel nanoplasmonic sensing chip based on SERS for viral screening and variants identification
    Authors: Yi Liu, Huanjiao Weng, Zhiwei Chen, … Shangyuan Feng, Duo Lin
    Year: 2025

 

  1. Title: tRNA methyltransferase DNMT2 promotes hepatocellular carcinoma progression and enhances Bortezomib resistance through inhibiting TNFSF10
    Authors: Junzhong Lai, Linqin Chen, Qiumei Li, … Jizhen Lin, Qi Chen
    Year: 2025

 

  1. Title: Carrimycin ameliorates lipopolysaccharide and cecal ligation and puncture-induced sepsis in mice
    Authors: Junzhong Lai, Jiadi Liang, Kunsen Chen, … Qi Chen, Jizhen Lin
    Year: 2024

 

  1. Title: B7H3 targeting gold nanocage pH-sensitive conjugates for precise and synergistic chemo-photothermal therapy against NSCLC
    Authors: Bing Chen, Kaifan Zheng, Shubin Fang, … Jizhen Lin, Xinhua Lin
    Year: 2023

 

  1. Title: A drug-delivery depot for epigenetic modulation and enhanced cancer immunotherapy
    Authors: Junzhong Lai, Jiadi Liang, Yong Zhang, … Jizhen Lin, Qi Chen
    Year: 2023

 

  1. Title: Ultrasensitive detection of SARS-CoV-2 antigen using surface-enhanced Raman spectroscopy-based lateral flow immunosensor
    Authors: Shuxia Lai, Yi Liu, Shubin Fang, … Jizhen Lin, Shangyuan Feng
    Year: 2023

 

  1. Title: Retraction Note to: Linc00210 drives Wnt/β-catenin signaling activation and liver tumor progression through CTNNBIP1-dependent manner
    Authors: Xiaomin Fu, Xiaoyan Zhu, Fujun Qin, … Qinxian Zhang, Quanli Gao
    Year: Not specified

 

  1. Title: SFPQ Promotes Lung Cancer Malignancy via Regulation of CD44 v6 Expression
    Authors: Libang Yang, Jiangbo Yang, Blake A. Jacobson, … Craig A. Henke, Jizhen Lin
    Year: 2022

 

✅ Conclusion

Dr. Lin’s lifelong commitment to understanding the science of hearing has positioned him as a pioneering figure in otolaryngology. Through decades of research, academic guidance, and clinical collaboration, he has built a legacy rooted in translational science and patient-centered innovation. His work continues to influence both basic research and clinical practice, promising a future where auditory health is better understood and more effectively managed. As a scientist, mentor, and innovator, Dr. Lin stands as an enduring contributor to the advancement of hearing science.

Dinh Phong Son | CircRNA | Best Researcher Award

Posted on by Neuroscientists

Dr. Dinh Phong Son | CircRNA | Best Researcher Award

Dr. DINH PHONG SON, DUYTAN UNIVERSITY, Vietnam.

Dr. Dinh Phong Son is a researcher specializing in laboratory medicine techniques with a Ph.D. in Molecular Medicine from Guangxi Medical University, China. His research focuses on modern molecular biology techniques, particularly the identification of potential biomarkers for early disease diagnosis and targeted therapy. His studies explore systemic diseases such as diabetes, cardiovascular diseases, and cancer, emphasizing gene editing technologies like CRISPR/Cas9. His recent publications contribute to the understanding of regulatory RNA networks and their implications in disease mechanisms, providing a foundation for future studies on molecular interactions and targeted drug development.

Profile

Orcid

 

🎓 Early Academic Pursuits

From the very beginning of my academic journey, I was deeply fascinated by the intricate mechanisms of life at a molecular level. My pursuit of knowledge led me to study Laboratory Medicine Technique at Hue University of Medicine and Pharmacy, Vietnam, where I honed my expertise in diagnostic methodologies and medical laboratory sciences. With an insatiable thirst for discovery, I furthered my education by earning a Doctorate (Ph.D.) in Molecular Medicine from Guangxi Medical University, China. This academic foundation set the stage for my dedication to the field of molecular biology, shaping my vision to explore genetic markers and innovative diagnostic tools.

👩‍🎓 Professional Endeavors

Currently, I serve at Duy Tan University, College of Medicine and Pharmacy, where I actively contribute to research, mentoring, and academic discourse. My work primarily revolves around molecular diagnostics, genetic analysis, and disease biomarker identification, aiming to bridge the gap between molecular biology and clinical applications. With advancements in next-generation sequencing (NGS) and bioinformatics databases, I continually seek new pathways to enhance the precision of disease detection and treatment strategies.

🧪 Contributions and Research Focus

My research is deeply rooted in molecular medicine, focusing on the identification of potential biomarkers for the early diagnosis of systemic diseases such as diabetes, cardiovascular diseases, stroke, and cancer. My investigations also extend to exploring gene targets for pharmacological studies, assisting in drug development through the modulation of gene expression using cutting-edge technologies like CRISPR/Cas9, gene overexpression, and silencing approaches. Furthermore, my work delves into the complex LncRNA/CircRNA/miRNA/gene/protein-drug interaction networks, paving the way for theoretical models that could revolutionize targeted therapy research.

 

💎 Impact and Influence

The impact of my research extends beyond academia, as it plays a crucial role in early disease screening, personalized medicine, and therapeutic advancements. By leveraging molecular networks, I aim to facilitate the development of precise diagnostic tools and gene-targeted interventions, significantly improving patient outcomes. My research findings have the potential to reshape biomedical applications and create avenues for innovative treatment strategies across various diseases.

🌟 Legacy and Future Contributions

Looking ahead, my aspirations remain steadfast in expanding molecular biology research, particularly in uncovering novel biomarkers and refining gene-editing techniques. As the field continues to evolve, I hope to contribute to the refinement of therapeutic gene modifications and biomarker-based diagnostics. With sustained efforts and collaborations, I envision a future where my research serves as a cornerstone for breakthroughs in precision medicine, targeted gene therapy, and advanced molecular diagnostics.

👨‍💼 Professional Collaborations and Memberships

As an active member of the scientific community, I engage in collaborations and professional affiliations to foster knowledge exchange and multidisciplinary research. My involvement in editorial appointments, consultancy projects, and industry partnerships enables me to extend my research impact, ensuring that molecular medicine continues to advance for the benefit of humanity.

 

Publication

  • Title: Identification and assessment of hub genes and miRNAs coregulatory associated with immune infiltrations and drug interactions in latent tuberculosis based on Microarray Data analysis, molecular docking, and dynamic simulation
    Authors: PhongSon Dinh, ChauMyThanh Tran, ThiPhuongHoai Dinh, Hai-Anh Ha, Aigul Utegenova, Awais Ali, Abdulaziz Alamri
    Year: 2025

 

  • Title: Hsa_circRNA_0000284 acts as a ceRNA to participate in coronary heart disease progression by sponging miRNA-338-3p via regulating the expression of ETS1
    Authors: PhongSon Dinh, ChauMyThanh Tran, ThiPhuongHoai Dinh, Awais Ali, ShangLing Pan
    Year: 2024

 

  • Title: Potential diagnostic value of serum microRNAs for 19 cancer types: a meta-analysis of bioinformatics data
    Authors: ChauMyThanh Tran, PhongSon Dinh
    Year: 2024

 

  • Title: Identification of hsa_circ_0001445 of a novel circRNA-miRNA-mRNA regulatory network as potential biomarker for coronary heart disease
    Authors: PhongSon Dinh, JunHua Peng, ThanhLoan Tran, DongFeng Wu, ChauMyThanh Tran, ThiPhuongHoai Dinh, ShangLing Pan
    Year: 2023

 

  • Title: Construction of miRNAs and gene expression profiles associated with ischemic cardiomyopathy: Bioinformatics analysis
    Authors: PhongSon Dinh, Jun-Hua Peng, ChauMyThanh Tran, ThanhLoan Tran, Shang-Ling Pan
    Year: 2022

 

Conclusion

Dr. Son’s research plays a crucial role in advancing molecular biology by identifying key biomarkers and regulatory networks for disease screening and treatment. His work in gene-targeted therapy and RNA interaction networks lays the groundwork for future innovations in precision medicine. Despite challenges in resources and time, his commitment to molecular research aims to drive further advancements in understanding and treating complex diseases.

Bastian Höchst | Onco- Immunology | Best Researcher Award

Posted on by Neuroscientists

Dr. Bastian Höchst | Onco- Immunology | Best Researcher Award

Dr. Bastian Höchst,  Institute of Molecular Immunology, MRI, TUM, Germany.

Bastian Höchst is a distinguished molecular immunologist whose career spans groundbreaking research, impactful teaching, and valuable contributions to the scientific community. His academic journey began with a focus on biology and culminated in a doctorate on immune regulation in liver tumors. As a Research Group Leader at the Technical University of Munich, he investigates the complex interplay of immune cells and tissues in acute and chronic inflammation. His pioneering discoveries, such as the mechanisms governing myeloid suppressor cells and immune-regulatory metabolite transfer, have advanced understanding in the field.

Profile

Google Scholar

🌱 Early Academic Pursuits

Bastian Höchst began his academic journey with a passion for understanding the intricate mechanisms of biology. From 1999 to 2005, he pursued his studies in Biology at the University of Bonn and Hamburg, laying the foundation for his future endeavors in molecular immunology. His academic curiosity led him to pursue a doctorate at the Medical School Hannover under the guidance of Prof. Dr. Tim F. Greten. His doctoral research focused on identifying and characterizing myeloid-derived suppressor cells in patients with hepatocellular carcinoma, marking the beginning of his impactful contributions to the field of immunology.

🔬 Professional Endeavors

Currently serving as a Research Group Leader at the Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University of Munich (TUM), Bastian Höchst has dedicated his career to unraveling the complexities of immune regulation. His journey in academia has been marked by significant roles, including his previous tenure as a Research Group Leader at the Institute for Animal Physiology and Immunology, Wissenschaftszentrum Weihenstephan, TUM. Additionally, his postdoctoral fellowship at the Institute of Molecular Medicine and Experimental Immunology at the University of Bonn further honed his expertise in immune mechanisms.

🧪 Contributions and Research Focus

Bastian Höchst’s research delves into immune regulation within acute and chronic inflammatory processes, with a particular focus on tissue-specific mechanisms. He has made groundbreaking discoveries, including elucidating the pathways that govern the generation of myeloid suppressor cells in liver tumors. Furthermore, his innovative work revealed that the intercellular transfer of immune-regulatory metabolites is critical to T-cell effector functions. His research has significantly advanced the understanding of immune responses in disease contexts, bridging gaps in immunological knowledge.

🎓 Teaching and Mentorship

A dedicated educator, Bastian Höchst has been actively involved in teaching since 2010, inspiring students in life sciences programs at TUM. His lectures on topics such as onco-immunology, immune metabolism, and immunotherapy provide invaluable insights to aspiring scientists. Through lab courses on immune cell phenotyping and advanced techniques like spectral flow cytometry, he has empowered students with the skills to explore the complexities of immunology. His teaching contributions extend beyond knowledge dissemination, fostering a generation of critical thinkers and innovators.

📜 Accolades and Recognition

Bastian’s expertise has been recognized through his habilitation and venia legendi for Molecular Immunology, under the mentorship of Prof. Dr. Percy Knolle. His contributions as a scientific reviewer for prestigious journals like Hepatology, Journal of Hepatology, and Frontiers in Immunology further reflect his authority in the field. Additionally, his role in evaluating grant applications for the Deutsche Forschungsgemeinschaft (DFG) underscores his impact on shaping future research initiatives.

🌍 Impact and Influence

Through his research, teaching, and reviews, Bastian Höchst has left an indelible mark on the field of molecular immunology. His work not only uncovers critical mechanisms of immune regulation but also provides pathways for therapeutic advancements in inflammatory and tumor-related conditions. His contributions influence both scientific understanding and practical applications, addressing global challenges in health and disease management.

🌟 Legacy and Future Contributions

Bastian Höchst’s journey is one of passion, discovery, and impact. As he continues to lead groundbreaking research, he sets the stage for a future where immune-based therapies are revolutionized. His legacy lies in his ability to connect fundamental research with real-world applications, inspiring colleagues and mentees alike. With his unwavering commitment to scientific exploration, Bastian Höchst is poised to shape the future of molecular immunology, paving the way for transformative breakthroughs.

Publication

  • A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4+ CD25+ Foxp3+ T cells
    Authors: B. Höchst, L.A. Ormandy, M. Ballmaier, F. Lehner, C. Krüger, M.P. Manns, …
    Year: 2008

 

  • Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor
    Authors: B. Höchst, T. Voigtlaender, L. Ormandy, J. Gamrekelashvili, F. Zhao, …
    Year: 2009

 

  • Functional classification of memory CD8+ T cells by CX3CR1 expression
    Authors: J.P. Böttcher, M. Beyer, F. Meissner, Z. Abdullah, J. Sander, B. Höchst, …
    Year: 2015

 

  • Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells
    Authors: B. Höchst, J. Gamrekelashvili, M.P. Manns, T.F. Greten, F. Korangy
    Year: 2011

 

  • S100A9 a new marker for monocytic human myeloid‐derived suppressor cells
    Authors: F. Zhao, B. Höchst, A. Duffy, J. Gamrekelashvili, S. Fioravanti, M.P. Manns, …
    Year: 2012

 

  • Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal
    Authors: T. Baumann, A. Dunkel, C. Schmid, S. Schmitt, M. Hiltensperger, K. Lohr, …
    Year: 2020

 

  • Kupffer cell-derived Tnf triggers cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS
    Authors: D. Yuan, S. Huang, E. Berger, L. Liu, N. Gross, F. Heinzmann, M. Ringelhan, …
    Year: 2017

 

  • Low-dose cyclophosphamide treatment impairs regulatory T cells and unmasks AFP-specific CD4+ T-cell responses in patients with advanced HCC
    Authors: T.F. Greten, L.A. Ormandy, A. Fikuart, B. Höchst, S. Henschen, M. Hörning, …
    Year: 2010

 

Conclusion

Bastian Höchst’s career exemplifies dedication to advancing molecular immunology through innovative research, education, and mentorship. His contributions have shaped the understanding of immune responses in disease contexts, offering hope for novel therapeutic approaches. As he continues to lead impactful research and foster new talent, Bastian Höchst remains a visionary in his field, poised to drive future breakthroughs that bridge science and medicine for the benefit of society.

 

Liliane Massade | Targeted therapy | Innovation in Neuroscience Award

Posted on by Neuroscientists

Liliane Massade | Targeted therapy | Innovation in Neuroscience Award

Dr. Liliane Massade, INSERM, France.

Dr. Liliane Massade is a visionary research leader whose work integrates molecular biology, nanotechnology, and translational medicine. From her academic roots in Lebanon to her pioneering research in France, she has achieved significant milestones, including the development of siRNA-based therapies for Charcot-Marie-Tooth disease and innovations in neurodegenerative and cancer treatments. Her career spans decades of groundbreaking discoveries, interdisciplinary collaborations, and impactful mentorship. With over 78 publications, patents, and numerous awards, Dr. Massade’s contributions are both scientifically profound and globally influential.

Profile

Orcid

🌟 Early Academic Pursuits

Dr. Liliane Massade’s academic journey began with her passion for biology and education. After earning her Master’s in Biology from Lebanese University in 1982, she followed her calling as a teacher, obtaining a Teaching Diploma from Ecole Normale, Lebanon, in 1981. Her thirst for knowledge led her to Paris Diderot University, where she completed an Advanced Studies Diploma (DEA) in Population Genetics and Evolution in 1986. By 1990, she had earned her Ph.D. in Population Genetics and Evolution, marking the start of her illustrious career. In 1996, she achieved the Authorization to Supervise Research (HDR), solidifying her role as a mentor and leader in her field.

🔬 Professional Endeavors

Dr. Massade’s career has been a symphony of innovation, leadership, and groundbreaking research. Since 2020, she has led a cutting-edge team at U1195 INSERM, Bicêtre University Hospital, focusing on targeted therapies for chemotherapy-induced peripheral neuropathies. Prior to this, she helmed teams at UMR 8203 CNRS, Gustave Roussy Institute, where she advanced anti-cancer therapies and explored molecular targets in thyroid cancer. Her earlier work at INSERM and CNRS saw her delve into estradiol signaling in breast cancer and enzymes in drug metabolism, laying the foundation for her expertise in molecular biology and translational medicine.

💡 Contributions and Research Focus

Dr. Massade’s pioneering spirit has transformed the fields of neurodegenerative diseases and oncology. She is celebrated for her groundbreaking siRNA-based therapies targeting PMP22, which have opened new horizons for Charcot-Marie-Tooth disease treatment. Her innovations extend beyond therapy, as her patented methods in nucleic acid transfer highlight her interdisciplinary approach. With a focus on integrating biology, chemistry, and nanotechnology, she leads research that merges fundamental science with clinical application, offering hope for conditions like peripheral neuropathy and neurodegeneration.

🏆 Accolades and Recognition

Throughout her career, Dr. Massade has earned prestigious accolades, including the Outstanding Achievement Award at the World Congress on Advances in Oncology in 2013 and the JW Griffin Prize for Regeneration from the Peripheral Nerve Society in 2021. Her impact is further underscored by her extensive publication record, with 78 works, an H-index of 26, and over 49 invited talks at international conferences. These honors reflect her global influence and her ability to inspire the next generation of researchers.

🌍 Impact and Influence

Dr. Massade’s contributions extend beyond her lab, as she evaluates research programs for renowned organizations like the ERC, ANR, and ARC. As a member of international committees such as LaBEX NanoSaclay, she ensures the advancement of cutting-edge nanotechnology. Her mentorship has shaped the careers of 10 postdoctoral researchers, 11 Ph.D. candidates, and 31 Master’s students, demonstrating her commitment to nurturing scientific talent.

🔗 Legacy and Future Contributions

As the co-founder of MAAsiRNA, Dr. Massade exemplifies the translation of research into real-world impact. With €7 million raised to develop therapies targeting PMP22, her work bridges the gap between science and patient care. Her vision for the future includes continued exploration of siRNA therapies and the development of innovative approaches to neuroprotection and cancer treatment. Her legacy is one of scientific excellence, interdisciplinary collaboration, and unwavering dedication to improving lives through research.

📚Publications

  • GRT-X Stimulates Dorsal Root Ganglia Axonal Growth in Culture via TSPO and Kv7.2/3 Potassium Channel Activation
    Authors: Léa El Chemali, Suzan Boutary, Song Liu, Guo-Jun Liu, Ryan J. Middleton, Richard B. Banati, Gregor Bahrenberg, Rainer Rupprecht, Michael Schumacher, Liliane Massaad-Massade
    Year: 2024

 

  • Optimizing Structure and Activity of the Squalenoyl-siRNA Nanoparticles
    Author: Liliane Massaad-Massade
    Year: 2023

 

  • Mutation of Proteolipid Protein 1 Gene: From Severe Hypomyelinating Leukodystrophy to Inherited Spastic Paraplegia
    Authors: Guy Khalaf, Claudia Mattern, Mélina Begou, Odile Boespflug-Tanguy, Charbel Massaad, Liliane Massaad-Massade
    Year: 2022

 

  • The Mitochondrial Translocator Protein (TSPO): A Key Multifunctional Molecule in the Nervous System
    Authors: Léa El Chemali, Yvette Akwa, Liliane Massaad-Massade
    Year: 2022

 

  • Supramolecular Organization and Biological Interaction of Squalenoyl siRNA Nanoparticles
    Authors: Marie Caillaud, Frédéric Gobeaux, Miryana Hémadi, Suzan Boutary, Patrick Guenoun, Didier Desmaële, Patrick Couvreur, Frank Wien, Fabienne Testard, Liliane Massaad-Massade
    Year: 2021

 

  • Squalenoyl siRNA PMP22 Nanoparticles Are Effective in Treating Mouse Models of Charcot-Marie-Tooth Disease Type 1A
    Author: Liliane Massaad-Massade
    Year: 2021

 

  • Treating PMP22 Gene Duplication-Related Charcot-Marie-Tooth Disease: The Past, the Present, and the Future
    Author: Liliane Massaad-Massade
    Year: 2020

 

  • Small Interfering RNA From the Lab Discovery to Patients’ Recovery
    Authors: Marie Caillaud, Mévidette El Madani, Liliane Massaad-Massade
    Year: 2020

 

  • Newly Identified LMO3-BORCS5 Fusion Oncogene in Ewing Sarcoma at Relapse Is a Driver of Tumor Progression
    Author: Liliane Massaad-Massade
    Year: 2019

 

  • A Novel Therapeutic Approach to Colorectal Cancer in Diabetes: Role of Metformin and Rapamycin
    Author: Liliane Massaad-Massade
    Year: 2019

 

  • Discovery of New Fusion Transcripts in a Cohort of Pediatric Solid Cancers at Relapse and Relevance for Personalized Medicine
    Author: Liliane Massaad-Massade
    Year: 2019

 

🌟 Conclusion

Dr. Liliane Massade is a beacon of innovation and leadership in molecular biology and targeted therapies. From her academic beginnings in Lebanon to her groundbreaking contributions in France, she has forged a path of excellence that inspires scientists worldwide. With her unparalleled expertise and passion, she continues to redefine the possibilities of modern medicine, leaving an indelible mark on science and humanity.