Hongrui Meng | Neurodegenerative disease | Excellence in Research Award

Prof. Dr. Hongrui Meng | Neurodegenerative disease | Excellence in Research Award

Prof. Dr. Hongrui Meng,  Institute of Neuroscience, Soochow University, China.

Dr. Hongrui Meng is a highly accomplished neuroscientist whose academic path began with a Ph.D. in Behavioural Neuroscience from Hamamatsu University School of Medicine in Japan. He later conducted postdoctoral research in molecular neurobiology and human genetics at Juntendo University, Tokyo. Currently a professor at the Institute of Neuroscience, Soochow University, Dr. Meng leads a research team dedicated to uncovering the molecular and mitochondrial mechanisms underlying Parkinson’s disease and ALS. His work spans high-impact research projects funded by JSPS, NSFC, and other prestigious bodies. In addition to numerous scientific publications, he has contributed to diagnostic innovation through patented miRNA detection methods. His influence extends beyond academia through translational applications such as wearable technologies for Parkinson’s symptom monitoring.

Profile

Orcid

🎓 Early Academic Pursuits

Dr. Hongrui Meng began his distinguished academic journey in the field of neuroscience by earning his Ph.D. in Behavioural Neuroscience from the prestigious Hamamatsu University School of Medicine in Japan. His early education and training laid a strong foundation in experimental neuroscience, with a focus on the behavioral manifestations of neurodegenerative conditions. These formative years not only sharpened his scientific curiosity but also equipped him with the cross-disciplinary expertise to address complex neurological questions.

🧠 Professional Endeavors

Following his doctoral studies, Dr. Meng advanced his specialization through postdoctoral training in molecular neurobiology and human genetics at Juntendo University in Tokyo. There, he immersed himself in high-level research focusing on the genetic underpinnings of neurological disorders. His competence and dedication soon earned him a faculty appointment as an Assistant Professor in the Department of Research for Neurodegenerative Diseases and Dementia. His professional arc reached a significant milestone in 2020 when he was promoted to Full Professor and moved to the Institute of Neuroscience at Soochow University, where he now leads the Laboratory of Molecular Neurology.

🧬 Contributions and Research Focus

Dr. Meng’s scientific contributions center on the molecular mechanisms of Parkinson’s disease and amyotrophic lateral sclerosis (ALS). His research bridges mitochondrial dysfunction, alpha-synuclein aggregation, and neurodegeneration. He has completed pivotal studies supported by the Japan Society for the Promotion of Science and the Takeda Pharmaceutical Foundation, delving into the role of CHCHD2 gene mutations and mitochondrial pathways. His ongoing projects funded by the National Natural Science Foundation of China (NSFC) explore mitochondrial unfolded protein responses (mtUPR), while another innovative project in Suzhou focuses on wearable technology for monitoring Parkinson’s disease symptoms—demonstrating his commitment to translational and patient-centered neuroscience.

🔬 Innovation and Scientific Output

A notable innovator, Dr. Meng has made strides in molecular diagnostic technologies. His work has led to the development of high-throughput RT-qPCR-based methods for detecting primary and precursor miRNAs, contributing to enhanced genetic analysis of neurodegenerative disorders. He holds a patent granted in South Africa and another under process in China, underscoring his role at the intersection of research and technology. Furthermore, his publications in highly regarded journals like Current Issues in Molecular Biology and Cell Communication and Signaling reflect a consistent record of impactful findings that inform both fundamental neuroscience and clinical approaches.

🏅 Accolades and Recognition

Dr. Meng’s ascent in the academic community has been marked by numerous grants, including multiple from the JSPS and NSFC, attesting to the trust placed in his research vision by top funding bodies. While a formal list of awards may be under-documented, his rapid progression from postdoctoral fellow to professor and research team leader in less than a decade speaks volumes about his recognition among peers and institutional leadership. His leadership in multi-disciplinary and international collaborations is an implicit accolade of his scientific reliability and visionary perspective.

🌍 Impact and Influence

Through his groundbreaking work on mitochondrial mechanisms and neurodegeneration, Dr. Meng is helping to reshape current understanding of Parkinson’s disease pathophysiology. His investigations into alpha-synucleinopathy and microglial disruption have provided fresh insights into cellular degeneration and neuroimmune interactions. Beyond academia, his involvement in developing wearable diagnostic tools highlights his drive to impact patient lives directly. As a consultant on neuroprotective treatments such as PD-018/19, he bridges the academic and pharmaceutical worlds to accelerate therapeutic discovery.

🔮 Legacy and Future Contributions

Looking forward, Dr. Meng is poised to be a leading figure in neurogenetic diagnostics and therapeutic innovation. His laboratory at Soochow University serves as an incubator for future discoveries in neurodegenerative disease mechanisms, and his continued work in mitochondrial research promises to inform emerging therapies. With a growing publication record, international patents, and a robust research pipeline, Dr. Meng’s legacy will be one of bridging basic neuroscience with clinical application—paving the way for novel interventions and a better understanding of brain disorders in the molecular era.

Publication

 

  • Title: Dicer Is Involved in Cytotoxicity and Motor Impairment Induced by TBPH Deficiency
    Authors: Xiang Long, Yijie Wang, Hongrui Meng
    Year: 2025

 

  • Title: Transcriptomic analysis of lipid metabolism genes in Alzheimer’s disease: highlighting pathological outcomes and compartmentalized immune status
    Authors: Sun Y., Zhang Y., Jiang M., Long X., Miao Y., Du H., Zhang T., Meng H., Ma X.
    Year: 2024

 

  • Title: CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca2+ homeostasis
    Authors: Aya Ikeda, Hongrui Meng, Daisuke Taniguchi, Muneyo Mio, Manabu Funayama, Kenya Nishioka, Mari Yoshida, Yuanzhe Li, Hiroyo Yoshino, Tsuyoshi Inoshita et al.
    Year: 2024

 

  • Title: TDP-43 mutations-induced defects in miRNA biogenesis and cytotoxicity by differentially obstructing Dicer activity in Drosophila and in vitro
    Authors: Xiang Long, Mengni Jiang, Yongzhen Miao, Huanhuan Du, Ting Zhang, Zhuoya Ma, Jiao Li, Chunfeng Liu, Hongrui Meng
    Year: 2024

 

  • Title: A Simple Technique to Assay Locomotor Activity in Drosophila
    Authors: Long X., Du H., Jiang M., Meng H.
    Year: 2023

 

  • Title: Functional MHCI deficiency induces ADHD-like symptoms with increased dopamine D1 receptor expression
    Authors: Meng H.-R., Suenaga T., Edamura M., Nakahara D., Murakami G., Fukuda A., Ishida Y.
    Year: 2021

 

  • Title: Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease
    Authors: Imai Y., Hattori N., Inoshita T., Shiba-Fukushima K., Meng H., Hara K.Y., Sawamura N.
    Year: 2019

 

  • Title: Mutations in CHCHD2 cause α-synuclein aggregation
    Authors: Ikeda A., Nishioka K., Takanashi M., Li Y., Mori A., Okuzumi A., Izawa N., Ishikawa K.-I., Funayama M., Imai Y. et al.
    Year: 2019

 

  • Title: Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling
    Authors: Mori A., Hatano T., Koinuma T., Kubo S.-I., Spratt S., Yamashita C., Okuzumi A., Imai Y., Hattori N., Inoshita T. et al.
    Year: 2019

 

  • Title: Twin CHCH proteins, CHCHD2, and CHCHD10: Key molecules of Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementia
    Authors: Imai Y., Hattori N., Meng H., Shiba-Fukushima K.
    Year: 2019

 

🧾 Conclusion

Dr. Hongrui Meng’s career reflects a dynamic blend of academic excellence, molecular research innovation, and translational neuroscience. His scientific endeavors have not only enriched the understanding of neurodegenerative diseases but have also paved the way for novel diagnostic and therapeutic strategies. With a growing portfolio of impactful research, patents, and leadership in neurobiology, Dr. Meng stands out as a driving force in the global fight against neurological disorders. His work promises continued contributions to neuroscience with lasting influence on both scientific knowledge and patient care.

 

Nai-Bing Gu | Clinical Neuroscience | Best Researcher Award

Prof. Dr. Nai-Bing Gu | Clinical Neuroscience | Best Researcher Award

Dr. Gu Naibing is a distinguished Chief Physician in the Department of Neurology at Xi’an Central Hospital, specializing in neuroimmunology. He has made significant contributions to the understanding of neurological diseases, particularly those related to autoimmune and inflammatory conditions of the nervous system. As a Master’s degree supervisor and an active member of several professional committees, Dr. Gu has established himself as a leader in the fields of neurology and neuroimmunology. His research, clinical expertise, and involvement in medical organizations have earned him recognition and influence in the medical community. His work continues to have a lasting impact on both the treatment of neurological diseases and the education of future healthcare professionals.

Profile

Scopus

 

👨‍⚕️ Early Academic Pursuits

Dr. Gu Naibing embarked on his academic journey with a keen interest in neurology and medicine. After completing his medical degree, he pursued further studies in the specialized field of neurology, which led to the completion of his Master’s degree. Throughout his academic tenure, Dr. Gu consistently demonstrated a strong dedication to advancing his understanding of complex neurological conditions. His early academic endeavors set the foundation for a career focused on improving patient outcomes and advancing scientific knowledge in neuroimmunology.

💼 Professional Endeavors

Dr. Gu Naibing has established himself as a prominent figure in the field of neurology. As a Chief Physician in the Department of Neurology at Xi’an Central Hospital, he plays a vital role in diagnosing and treating a wide range of neurological disorders. Additionally, he serves as a Master’s degree supervisor, contributing to the training and development of the next generation of medical professionals. His professional network includes multiple roles in prestigious committees, such as the Neuroimmunology Professional Committee of the Shaanxi Provincial International Medical Exchange Promotion Association and the Neurology Branch of the Xi’an Medical Association.

🔬 Contributions and Research Focus

Dr. Gu’s research primarily focuses on neuroimmunology, the intersection of the immune system and neurological diseases. His work has advanced understanding in this field, particularly with regard to the mechanisms underlying autoimmune disorders affecting the nervous system. By contributing to a deeper understanding of brain diseases, Dr. Gu’s research has had significant implications for the development of more effective treatments for patients suffering from conditions such as multiple sclerosis, encephalitis, and other neuroinflammatory disorders. His focus on integrating immunological and neurological disciplines has been pivotal in pushing the boundaries of clinical research.

🏆 Accolades and Recognition

Throughout his career, Dr. Gu Naibing has earned several accolades and recognition for his outstanding contributions to the medical field. His involvement in various professional committees highlights his leadership and influence in the realm of neurology and neuroimmunology. As a standing committee member of the Neuroimmunology Group and the Neurology Professional Committee of the Shaanxi Health Care Association, Dr. Gu’s expertise and leadership are regularly sought after. His recognition extends beyond clinical practice, as he is frequently invited to contribute to national and international discussions on neurological care and research.

🌍 Impact and Influence

Dr. Gu Naibing’s influence extends beyond his clinical and research activities. Through his active involvement in professional organizations, he has had a profound impact on the development of neurology and neuroimmunology practices in China. His leadership in committees, particularly within the Shaanxi Medical Communication Association, has helped bridge gaps between medical professionals, facilitating the exchange of ideas and research findings. His dedication to fostering collaboration among medical communities has contributed to the enhancement of healthcare practices and the overall improvement of patient care.

🧠 Legacy and Future Contributions

As Dr. Gu Naibing continues his work, his legacy in the fields of neurology and neuroimmunology will undoubtedly inspire future generations of healthcare professionals. His commitment to advancing both clinical and research practices ensures that his contributions will have a lasting impact on the treatment of neurological diseases. Looking ahead, Dr. Gu is poised to continue making significant strides in neuroimmunology, with ongoing research and collaborations aimed at developing new therapeutic approaches. His future contributions promise to further shape the landscape of neurological healthcare, enhancing the lives of patients around the world.

🌟 Final Thoughts

Dr. Gu Naibing’s career has been defined by his passion for neurology, his commitment to advancing research, and his tireless efforts to improve patient outcomes. As a clinician, educator, and researcher, he has earned the respect and admiration of his peers, contributing significantly to the advancement of medical knowledge and patient care. With his continued dedication to the field, Dr. Gu’s legacy is sure to endure, influencing both the scientific community and the generations of healthcare professionals who follow in his footsteps.

Publication

  • Title: Effect of BMSCs overexpressing intelectin-1 on angiogenesis in rats with cerebral infarction
    Authors: B. Zhu, K. Guo, L. Zha, L. Chang, N. Gu
    Year: 2025

 

  • Title: Salivary duct carcinoma presenting with unilateral multiple cranial nerve lesions and concurrent intracranial metastasis: A case report
    Authors: B. Zhu, Q. Zhang, K. Guo, Y. Yang, X. Jia
    Year: 2025

 

Conclusion

Dr. Gu Naibing’s career is a testament to his dedication to advancing the field of neurology and neuroimmunology. His groundbreaking research, leadership in medical committees, and commitment to education have shaped the future of neurological care in China. With his continued focus on improving patient care and expanding scientific knowledge, Dr. Gu is poised to make lasting contributions that will positively impact both the medical field and the lives of countless patients. His legacy will inspire future generations of researchers and clinicians in the realm of neurology.

 

Camilla Bellone | Translational Neuroscience | Best Researcher Award

Assoc. Prof. Dr. Camilla Bellone | Translational Neuroscience | Best Researcher Award

Assoc. Prof. Dr. Camilla Bellone,  University of Geneva, Switzerland.

Dr. Camilla Bellone is a renowned neuroscientist whose academic and research career has been marked by excellence, innovation, and impact. From her foundational training in Italy to her leadership role in Geneva, she has made pioneering contributions to understanding the neural underpinnings of social behavior. Her work bridges basic science and clinical relevance, and she has played a vital role in training, mentorship, and international collaboration within the neuroscience community.

Profile

Google Scholar

 

🎓 Early Academic Pursuits

Dr. Camilla Bellone began her academic journey with a Master’s degree in Pharmacy from the University of Milano in 2000. With a strong foundation in pharmacology and medical chemistry, she pursued her Ph.D. in “Pharmacology, Toxicology, and Medical Chemotherapy” at the same institution, completing it in 2006. Her early education shaped a robust scientific mindset, preparing her for a career at the intersection of neuroscience and pharmacology. These formative years set the tone for her later work on the molecular mechanisms that govern complex behaviors in both healthy and diseased states.

🧪 Professional Endeavors

After her doctoral studies, Dr. Bellone enhanced her research acumen through a postdoctoral fellowship at the University of California, San Francisco (UCSF), gaining international exposure. She later returned to Switzerland, where she served as a scientist under the Ambizione Fellowship at the University of Geneva. Her academic path took a significant leap when she became an Assistant Professor at the University of Lausanne in 2014, followed by a transition to the University of Geneva in 2016. In 2020, she was promoted to Associate Professor in the Department of Basic Neuroscience, where she continues to lead cutting-edge investigations and mentor future neuroscientists.

🧠 Contributions and Research Focus

At the core of Dr. Bellone’s research lies a deep interest in the neurobiological basis of social behavior, with a particular focus on how these processes are disrupted in neuropsychiatric disorders. Her lab explores the synaptic and circuit-level mechanisms that underpin social cognition, often using advanced molecular and behavioral techniques. Her work has provided critical insights into how alterations in neural plasticity and connectivity contribute to diseases such as schizophrenia and autism spectrum disorders. With over 40 peer-reviewed publications in high-impact journals like Nature Neuroscience and Neuron, Dr. Bellone’s research continues to advance the field of behavioral neuroscience.

🏆 Accolades and Recognition

Dr. Bellone’s scientific excellence has been recognized through several prestigious honors. In 2023, she received the EBBS Mid-Career Award and the Leenaards Scientific Prize for her collaborative project on cerebellar stimulation in schizophrenia. Earlier, she was elected to the distinguished FENS-KAVLI Network of Excellence in 2015, highlighting her position among Europe’s most promising neuroscientists. In 2014, she was honored with the Fondation du Prix Pfizer de la Recherche, marking an early milestone in her independent research career.

🌍 Impact and Influence

Beyond her lab, Dr. Bellone has made meaningful contributions to the academic and scientific community. She has delivered over 20 invited lectures at international conferences and institutions, sharing her discoveries with a global audience. As a dedicated mentor, she has guided eight master’s students and seven PhD candidates, nurturing the next generation of neuroscientists. Her commitment extends to active service on academic committees, grant review panels, and editorial boards, reflecting her role as a respected leader in the field.

👩‍🔬 Balancing Science and Life

A champion of work-life integration, Dr. Bellone has managed to thrive professionally while embracing motherhood. She took two career breaks following the birth of her three children, exemplifying resilience and balance in a demanding academic landscape. Her story is an inspiration to young scientists, especially women, striving to build careers in STEM while honoring personal life choices.

🔬 Legacy and Future Contributions

Looking ahead, Dr. Bellone’s work holds promise for transforming our understanding of social dysfunction in mental illness. Her innovative approaches—blending circuit neuroscience, pharmacology, and behavior—position her as a leading voice in the neurobiology of social behavior. With continued support from initiatives like the ERC Consolidator Grant, her research will likely pave the way for novel therapeutic interventions, leaving a lasting legacy in neuroscience and psychiatry.

Publication

  • Title: NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
    Author: P Paoletti, C Bellone, Q Zhou
    Year: 2013

 

  • Title: Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression
    Author: C Bellone, C Lüscher
    Year: 2006

 

  • Title: Rapid bidirectional switching of synaptic NMDA receptors
    Author: C Bellone, RA Nicoll
    Year: 2007

 

  • Title: Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area
    Author: M Mameli, C Bellone, MTC Brown, C Lüscher
    Year: 2011

 

  • Title: In vivo reprogramming of circuit connectivity in postmitotic neocortical neurons
    Author: A De la Rossa, C Bellone, B Golding, I Vitali, J Moss, N Toni, C Lüscher, …
    Year: 2013

 

  • Title: Mechanisms of synaptic depression triggered by metabotropic glutamate receptors
    Author: C Bellone, C Lüscher, M Mameli
    Year: 2008

 

  • Title: Effects of streptozotocin‐diabetes on the hippocampal NMDA receptor complex in rats
    Author: F Gardoni, A Kamal, C Bellone, GJ Biessels, GMJ Ramakers, F Cattabeni, …
    Year: 2002

 

  • Title: Neurons under T cell attack coordinate phagocyte-mediated synaptic stripping
    Author: G Di Liberto, S Pantelyushin, M Kreutzfeldt, N Page, S Musardo, R Coras, …
    Year: 2018

 

  • Title: mGluRs induce a long‐term depression in the ventral tegmental area that involves a switch of the subunit composition of AMPA receptors
    Author: C Bellone, C Lüscher
    Year: 2005

 

  • Title: SHANK3 controls maturation of social reward circuits in the VTA
    Author: S Bariselli, S Tzanoulinou, C Glangetas, C Prévost-Solié, L Pucci, …
    Year: 2016

 

✅ Conclusion

Dr. Bellone’s journey reflects a remarkable blend of scientific curiosity, academic leadership, and personal resilience. As she continues to explore the brain’s most intricate social circuits, her influence will undoubtedly expand across neuroscience, psychiatry, and therapeutic innovation. Her career serves as both a roadmap and an inspiration for emerging scientists navigating the evolving landscape of brain research.