Eleni Tsakiri | Foundations of Neuroscience | Best Researcher Award

Dr. Eleni Tsakiri | Foundations of Neuroscience | Best Researcher Award

Dr. Eleni Tsakiri |  National and Kapodistrian University of Athens Medical School | Greece

Dr. Eleni Tsakiri is a distinguished Molecular Biologist whose research centers on the molecular mechanisms of aging, proteostasis, and neurodegeneration. She earned her Ph.D. in Biology from the National and Kapodistrian University of Athens (NKUA) with a thesis on proteome homeostasis and its alterations during aging, following her M.Sc. in Cell Biology and Biophysics and a B.Sc. in Molecular Biology and Genetics. Dr. Tsakiri has held multiple postdoctoral positions at leading Greek institutions, including the Medical School of NKUA and the Biomedical Research Center “Alexander Fleming,” where she contributed to projects on proteasome regulation, Tau aggregation, and ribosome-mediated cell competition. Currently, she serves as a Postdoctoral Researcher at the Laboratory of Physiology, NKUA, focusing on neurodegeneration and aging under an ERC-funded project. Her research is supported by competitive grants such as the Hellenic Foundation for Research and Innovation (HFRI). She has supervised undergraduate, master’s, and doctoral students and actively collaborates with prominent researchers in Greece and abroad. Dr. Tsakiri’s contributions are reflected in her 24 published documents, 730 citations, and an h-index of 15, highlighting her impact in molecular biology and aging research.

Profiles: Scopus | Google Scholar | Research Gate | LInked In

Featured Publications

  • Tsakiri, E. N., Sykiotis, G. P., Papassideri, I. S., Terpos, E., Dimopoulos, M. A., & others. (2013). Proteasome dysfunction in Drosophila signals to an Nrf2‐dependent regulatory circuit aiming to restore proteostasis and prevent premature aging. Aging Cell, 12(5), 802–813.

  • Tsakiri, E. N., Sykiotis, G. P., Papassideri, I. S., Gorgoulis, V. G., Bohmann, D., & others. (2013). Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress. The FASEB Journal, 27(6), 2407–2419.

  • Tsakiri, E. N., & Trougakos, I. P. (2015). The amazing ubiquitin-proteasome system: Structural components and implication in aging. International Review of Cell and Molecular Biology, 314, 171–237.

  • Tsakiri, E. N., Iliaki, K. K., Höhn, A., Grimm, S., Papassideri, I. S., & Grune, T. (2013). Diet-derived advanced glycation end products or lipofuscin disrupts proteostasis and reduces life span in Drosophila melanogaster. Free Radical Biology and Medicine, 65, 1155–1163.

  • Tsakiri, E. N., Gumeni, S., Iliaki, K. K., Benaki, D., Vougas, K., Sykiotis, G. P., et al. (2019). Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation. Aging Cell, 18(1), e12845.

Daša Zupančič | Cellular Neuroscience | Best Researcher Award

Assoc. Prof. Dr. Daša Zupančič | Cellular Neuroscience | Best Researcher Award

Assoc. Prof. Dr. Daša Zupančič, Faculty of Medicine, University of Ljubljana, Slovenia.

Daša Zupančič is a distinguished academic and researcher specializing in cell biology, urothelial pathology, and medical education. Her extensive contributions to scientific research, particularly in the field of urothelial repair and cancer transformation, have earned her recognition, including the EMBO award. She has played a crucial role in mentoring and teaching, guiding future generations of researchers and medical professionals.

Profile

Orcid

✨ Early Academic Pursuits ✨

Daša Zupančič embarked on her academic journey with an unwavering passion for cell biology and medicine. She earned her Master’s degree in 2002 from the University of Ljubljana, Faculty of Medicine, where she meticulously explored cellular and molecular biological changes in the rat bladder urothelium following cyclophosphamide exposure. This formative research laid the foundation for her Ph.D., which she successfully completed in 2006, investigating the protective role of melatonin in urothelial injury and repair. Her dedication to advancing biomedical knowledge was evident from the very beginning of her scholarly career.

🎓 Professional Endeavors 🎓

Since 2006, Daša Zupančič has been an esteemed Associate Professor at the University of Ljubljana, Faculty of Medicine, Institute of Cell Biology. Prior to this, she gained valuable experience as a Young Researcher and Teaching Assistant from 1999 to 2006. Her extensive expertise and commitment to education have made her an integral part of the institution, where she continuously fosters scientific curiosity and excellence among students and colleagues alike.

🎡 Contributions and Research Focus 🎡

Throughout her career, Daša Zupančič has dedicated her research to understanding cellular mechanisms in urothelial biology and pathology. Her investigations into cyclophosphamide-induced urothelial injury, melatonin’s protective effects, and retinoid signaling pathways in urothelial cancer transformation have provided valuable insights into cellular repair processes. Her work extends beyond laboratory research, influencing the medical community’s approach to urothelial diseases and potential therapeutic advancements.

🏆 Accolades and Recognition 🏆

Her exceptional contributions to biomedical research have been recognized on multiple platforms. In 2017, she was honored with the prestigious EMBO award for her short-term scholarship project on the role of the retinoid signaling pathway in urothelial cancer transformation. This recognition underscores her significant impact on the scientific community and highlights her pioneering approach to understanding cancer pathophysiology.

👨‍🎓 Impact and Influence 👨‍🎓

A dedicated mentor, Daša Zupančič has guided numerous students towards academic excellence. Between 2014 and 2025, she has successfully mentored four master’s students and is currently supervising two more. In addition, she has overseen the research endeavors of four Ph.D. candidates, with one having successfully defended their dissertation in 2023 and another expected to graduate in 2025. Her mentorship has shaped the next generation of biomedical researchers, fostering a culture of rigorous inquiry and scientific discovery.

📚 Legacy and Future Contributions 📚

Beyond her research, Daša Zupančič plays a pivotal role in academia through her extensive teaching engagements. Since 2000, she has been a cornerstone of education at the University of Ljubljana, contributing to multiple faculties, including Medicine, Biotechnical Sciences, Health Sciences, and Pharmacy. She teaches a range of graduate and doctoral courses, covering essential subjects such as Medical Cell Biology, Immunology, and Research in Medicine. Her dedication to education ensures that her knowledge and expertise continue to shape the minds of aspiring medical professionals and researchers for years to come.

Publication

  • Vitamin A‐Enriched Diet Increases Urothelial Cell Proliferation by Upregulating Itga3 and Areg After Cyclophosphamide‐Induced Injury in Mice
    Authors: Brina Dragar, Simona Kranjc Brezar, Maja Čemažar, Tanja Jesenko, Rok Romih, Mateja Erdani Kreft, Tadeja Kuret, Daša Zupančič
    Year: 2025

 

  • Selective Targeting of Lectins and Their Macropinocytosis in Urothelial Tumours: Translation from in vitro to ex vivo
    Authors: Nataša Resnik, Tanja Višnjar, Tomaž Smrkolj, Mateja Erdani Kreft, Rok Romih, Daša Zupančič
    Year: 2023

 

  • Nanodiamonds as Possible Tools for Improved Management of Bladder Cancer and Bacterial Cystitis
    Authors: Daša Zupančič, Peter Veranič
    Year: 2022

 

  • Transmission Electron Microscopy Demonstration of Reduced Endothelial Glycocalyx in Severe Preeclampsia
    Authors: Mugerli S, Zupančič D, Rok Romih, Lučovnik M
    Year: 2022

 

  • Vitamin A and Retinoids in Bladder Cancer Chemoprevention and Treatment: A Narrative Review of Current Evidence, Challenges and Future Prospects
    Authors: Larisa Tratnjek, Jera Jeruc, Rok Romih, Daša Zupančič
    Year: 2021

 

  • Immunohistochemistry as a Paramount Tool in Research of Normal Urothelium, Bladder Cancer and Bladder Pain Syndrome
    Authors: Daša Zupančič, Rok Romih
    Year: 2021

 

  • Combined Lectin- and Immuno-Histochemistry (CLIH) for Applications in Cell Biology and Cancer Diagnosis: Analysis of Human Urothelial Carcinomas
    Authors: Daša Zupančič
    Year: 2020

 

  • Vitamin A Rich Diet Diminishes Early Urothelial Carcinogenesis by Altering Retinoic Acid Signaling
    Authors: Daša Zupančič, Jelena Korać-Prlić, Mateja Erdani Kreft, Lucija Franković, Katarina Vilović, Jera Jeruc, Rok Romih, Janoš Terzić
    Year: 2020

 

  • Lectins as Possible Tools for Improved Urinary Bladder Cancer Management
    Authors: Daša Zupančič
    Year: 2019

 

  • Co-Culturing Porcine Normal Urothelial Cells, Urinary Bladder Fibroblasts and Smooth Muscle Cells for Tissue Engineering Research
    Authors: Daša Zupančič
    Year: 2018

 

🌟 Conclusion 🌟

With a career dedicated to pioneering research, impactful mentorship, and transformative education, Daša Zupančič continues to leave a lasting legacy in the scientific and academic communities. Her work not only enhances understanding of urothelial biology but also inspires innovation and discovery among young scientists. As she continues her academic and research endeavors, her influence on the field will undoubtedly grow, shaping the future of biomedical sciences.