Gulcin Gacar | Neurodegenerative Disease | Best Researcher Award

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Assoc. Prof. Dr. Gulcin Gacar | Neurodegenerative Disease | Best Researcher Award

Prof. Dr. Gulcin Gacar | Kocaeli University | Turkey

Associate Professor Dr. Gulcin Gacar of Kocaeli University is a distinguished researcher and educator in the fields of stem cell biology, regenerative medicine, and clinical microbiology. With over 200 scientific publications, including 54 in Web of Science and 37 in Scopus, she has garnered more than 900 citations and achieved an h-index of 17. Her groundbreaking research focuses on mesenchymal stem cells and exosomes, particularly their applications in neurodegenerative diseases like Alzheimer’s. She leads nationally funded projects and serves as a mentor to graduate students, contributing significantly to Turkey’s scientific advancement in cellular and molecular therapy.

Academic Profile

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Early Academic Pursuits

From the outset of her academic journey, Dr. Gülçin Gacar exhibited a strong dedication to medical sciences, particularly clinical microbiology and regenerative medicine. Her foundational studies laid the groundwork for her specialization in stem cell biology and advanced biomedical techniques. As she advanced through the academic ranks, her commitment to translational research became evident, inspiring a deep dive into the dynamic world of mesenchymal stem cells and cellular therapies.

Professional Endeavors

Currently serving as an Associate Professor at Kocaeli University, Dr. Gacar is affiliated with the Center for Stem Cell and Gene Therapies under the Institute of Health Sciences. She plays a critical role in bridging theoretical knowledge with clinical application. Her professional journey is characterized by a robust combination of teaching, research, and leadership, where she supervises graduate-level research and oversees important institutional initiatives in stem cell-based innovation.

Contributions and Research Focus

Dr. Gacar’s research primarily revolves around mesenchymal stem cells, exosomes (extracellular vesicles), and advanced applications of stem cell biology. One of her key projects involves investigating the therapeutic potential of exosomes derived from adipose tissue-origin mesenchymal stem cells on Alzheimer’s disease models using human neuroblastoma SHSY5Y cells. This cutting-edge study, supported by national scientific funding, illustrates her focus on neurological disorders and cellular therapies. With over 200 academic publications, including 54 indexed in Web of Science and 37 in Scopus, her work has become a cornerstone in regenerative medicine and neurocellular research.

Accolades and Recognition

Dr. Gacar’s exceptional scholarship is reflected in her impressive citation record—garnering over 900 citations with an h-index of 16 on Web of Science and 17 on Scopus. These metrics not only underscore the academic relevance of her research but also highlight her influence in the global scientific community. Her contributions have positioned her as a key opinion leader and trusted consultant in TÜBİTAK-funded national projects, further validating her expertise and dedication to scientific excellence.

Impact and Influence

Beyond publications and projects, Dr. Gacar is actively involved in mentoring the next generation of scientists. She has supervised numerous graduate theses, fostering a research culture grounded in innovation, rigor, and ethical science. Her influence extends into policy-making and practical clinical research, making her a vital figure in the implementation of stem cell technologies in both experimental and therapeutic contexts.

Legacy and Future Contributions

Dr. Gacar continues to expand the frontiers of stem cell research and regenerative neuroscience. Her ongoing efforts in developing novel diagnostic and therapeutic modalities through cellular and molecular engineering are poised to transform clinical approaches to degenerative diseases. With each project and publication, she reinforces her commitment to scientific discovery and paves the way for future breakthroughs in biotechnology and personalized medicine.

Neuroscience and Regenerative Innovation

At the intersection of neuroscience and regenerative biology, Dr. Gacar’s work exemplifies the possibilities of interdisciplinary research. Her current focus on exosome-based therapies in neurodegenerative conditions represents a bold step into the future of non-invasive, cell-free therapeutics. As the landscape of neuroscience evolves, her pioneering work will undoubtedly contribute to novel clinical strategies and global scientific advancement.

Publication

Isolation and in vitro characterisation of dental pulp stem cells from natal teeth
E Karaöz, BN Doğan, A Aksoy, G Gacar, S Akyüz, S Ayhan, ZS Genç
2010

Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers
E Karaoz, A Aksoy, S Ayhan, AE Sarıboyacı, F Kaymaz, M Kasap
2009

Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum
K Schallmoser, E Rohde, A Reinisch, C Bartmann, D Thaler, C Drexler, …
2008

High prevalence of OXA-51-type class D β-lactamases among ceftazidime-resistant clinical isolates of Acinetobacter spp.: co-existence with OXA-58 in multiple …
H Vahaboglu, F Budak, M Kasap, G Gacar, S Torol, A Karadenizli, …
2006

Immunoregulatory effects of human dental pulp-derived stem cells on T cells: comparison of transwell co-culture and mixed lymphocyte reaction systems
PC Demircan, AE Sariboyaci, ZS Unal, G Gacar, C Subasi, E Karaoz
2011

Protective effects of resveratrol on aging-induced cognitive impairment in rats
SS Gocmez, N Gacar, T Utkan, G Gacar, PJ Scarpace, N Tumer
2016

The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets
AT Özdemir, RBÖ Özdemir, C Kırmaz, AE Sarıboyacı, ZSÜ Halbutoğlları, …
2016

PER-1 is still widespread in Turkish hospitals among Pseudomonas aeruginosa and Acinetobacter spp.
F Kolayli, G Gacar, A Karadenizli, A Sanic, H Vahaboglu, Study Group
2005

Phenotypic and proteomic characteristics of human dental pulp derived mesenchymal stem cells from a natal, an exfoliated deciduous, and an impacted third molar tooth
G Akpinar, M Kasap, A Aksoy, G Duruksu, G Gacar, E Karaoz
2014

The role of PIN1 on odontogenic and adipogenic differentiation in human dental pulp stem cells
YM Lee, SY Shin, SS Jue, IK Kwon, EH Cho, ES Cho, SH Park, EC Kim
2014

Conclusion 

Considering her scholarly output, impactful research on stem cell-based therapies, leadership in national research initiatives, and dedication to mentoring, Dr. Gulcin Gacar is highly deserving of the Best Researcher Award. Her innovative work in exosome-based treatment strategies for neurodegenerative diseases positions her as a leader in translational medical science. With continued emphasis on global engagement and high-impact dissemination, her research will not only advance scientific frontiers but also contribute meaningfully to patient care and public health. Thus, she stands as an exemplary model of academic excellence, innovation, and social relevance in biomedical sciences.

Rita Abi Rached | Neuropharmacology | Best Researcher Award

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Dr. Rita Abi Rached | Neuropharmacology | Best Researcher Award

Dr. Rita Abi Rached, University of Cagliari, Italy.

Rita Joseph Abi Rached has built a remarkable career at the intersection of food chemistry, biochemistry, and sustainability. From her foundational academic journey to her current research in agri-food by-product valorization, she has continuously sought innovative solutions to environmental and health-related challenges. Her expertise spans industry collaborations, cutting-edge research, and impactful scientific contributions, making her a leading figure in sustainable food science.

Profile

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✨ Early Academic Pursuits – A Passion for Science ✨

From an early age, Rita Joseph Abi Rached demonstrated an innate curiosity for the sciences, particularly in the fields of biochemistry and food chemistry. She embarked on her academic journey with a Bachelor’s degree in Biochemistry from Saint Joseph University of Beirut in 2017, where she cultivated a strong foundation in molecular sciences. Her passion for the chemical intricacies of food systems led her to pursue a Master’s degree in Food Chemistry in 2019, further refining her expertise in the biochemical properties of agro-food products. This academic dedication ultimately culminated in a Double Ph.D. in Life, Environmental, and Pharmaceutical Sciences from the University of Cagliari and Saint Joseph University of Beirut in 2024, marking a significant milestone in her scholarly endeavors.

🌱 Professional Endeavors – Bridging Academia and Industry 🌱

With an unwavering commitment to research, Rita transitioned from academia to professional scientific exploration. Her early training included hands-on experiences at Château Ksara, where she assessed grape phenolic maturity, and at Libby’s, where she gained insights into quality control and microbiological analyses. Further strengthening her industrial expertise, she worked as a lab researcher and research assistant at Saint Joseph University, refining her skills in polyphenol analysis and microbiological assessments. These experiences not only expanded her technical competencies but also paved the way for her role as a dedicated researcher at the University of Cagliari, where she currently investigates sustainable approaches to agri-food by-product valorization.

🤝 Contributions and Research Focus – Innovating for a Sustainable Future 🤝

Rita’s research is deeply rooted in sustainability and the innovative utilization of agricultural and industrial biomasses. Her current work revolves around the valorization of agro-industrial by-products, transforming waste into functional bioactive compounds for health and agriculture. She has actively contributed to groundbreaking projects such as BESTMEDGRAPE, which applied nanotechnological strategies to enhance Mediterranean grape derivatives, and MEDLENTISK, an Erasmus+ initiative that explored best practices for mastic tree fixed oil. Additionally, she played a pivotal role in TECNOCOVID, a project leveraging natural bioactives and nanotechnologies to combat COVID-19. Her most recent endeavor, NUTRINNOVA, focuses on utilizing nutriosomes derived from agro-industrial waste to mitigate dysbiosis, oxidative stress, and cognitive decline, further establishing her as a pioneer in sustainable food research.

🏆 Accolades and Recognition – A Scholar’s Journey 🏆

Throughout her career, Rita has garnered significant recognition for her impactful contributions to scientific research. Her work has been widely cited, with a citation index of 72 and an h-index of 4, reflecting her influence in the academic community. These achievements underscore the relevance of her studies in the fields of food science, biotechnology, and environmental sustainability. Her research outputs continue to inspire new approaches to the responsible and efficient use of natural resources, positioning her as a respected voice in her domain.

🔍 Impact and Influence – Shaping the Scientific Landscape 🔍

As an advocate for innovative and sustainable research, Rita’s work has transcended the boundaries of traditional food science, merging interdisciplinary methodologies to address global challenges. By focusing on agri-food waste valorization, she has provided meaningful insights into reducing environmental impact while enhancing the nutritional and therapeutic value of food by-products. Her collaborations with industry leaders and academic institutions have reinforced her reputation as a key contributor to cutting-edge scientific advancements.

 

Publication

  • Title: Entrapment of Citrus limon var. pompia Essential Oil or Pure Citral in Liposomes Tailored as Mouthwash for the Treatment of Oral Cavity Diseases
    Author(s): L Palmas, M Aroffu, GL Petretto, E Escribano-Ferrer, O Díez-Sales, …
    Year: 2020

 

  • Title: Extraction, Characterization and Incorporation of Hypericum scruglii Extract in Ad Hoc Formulated Phospholipid Vesicles Designed for the Treatment of Skin
    Author(s): M Allaw, M Manconi, M Aroffu, F Marongiu, M Porceddu, G Bacchetta, …
    Year: 2020

 

  • Title: Optimization of Polyphenols Extraction from Purple Corn Cobs Using ß-Cyclodextrin as a Green Solvent
    Author(s): HN Rajha, S Khabbaz, R Abi Rached, E Debs, RG Maroun, N Louka
    Year: 2020

 

  • Title: From Grape By-Products to Enriched Yogurt Containing Pomace Extract Loaded in Nanotechnological Nutriosomes Tailored for Promoting Gastro-Intestinal Wellness
    Author(s): I Castangia, F Fulgheri, FJ Leyva-Jimenez, ME Alañón, ML Cádiz-Gurrea, …
    Year: 2023

 

  • Title: From Field to Waste Valorization: A Preliminary Study Exploring the Impact of the Wine Supply Chain on the Phenolic Profile of Three Sardinian Pomace Extracts
    Author(s): I Castangia, M Aroffu, F Fulgheri, R Abi Rached, F Corrias, G Sarais, …
    Year: 2024

 

  • Title: Innovation in Cannon Puffing Technology for the Homogenization of Bulk Treatment: Half‐Popped Purple Corn, a New Healthy Snack
    Author(s): HN Rajha, E Debs, R Abi Rached, K El Khoury, M Al‐Kazzi, R Mrad, …
    Year: 2021

 

  • Title: Exploring the Efficacy and Industrial Potential of Polyphenol Products from Grapes and Their By-Products
    Author(s): R Abi Rached, M Perra, ML Manca, HN Rajha, N Louka, RG Maroun, …
    Year: 2024

 

  • Title: A Preliminary Investigation on Hydrogel Disks Imbibed with Enriched Transfersomes as a Promising Tool to Promote the Cutaneous Deposition of Vaccine Antigens
    Author(s): M Aroffu, R Abi Rached, I Castangia, P Italiani, L D’Apice, …
    Year: 2024

 

  • Title: Preliminary Evaluation of the In Vitro and In Vivo Efficacy of a Novel Nanovesicle-Doped Nanoemulsion Co-Loading Artemisinin and Quercetin as a Promising Strategy to Improve …
    Author(s): F Fulgheri, M Ramírez, L Román-Álamo, P Gasco, M Manconi, M Aroffu, …
    Year: 2025

 

  • Title: Clinical Trial to Evaluate the Effect of Grape Seed Extract-Loaded Hyalurosomes on Skin Wellness
    Author(s): RA Rached, M Habre, Y Salem, J Khodeir, M Allaw, I Castangia, …
    Year: 2025

 

🔗 Conclusion 🔗

With an unwavering passion for science and an unrelenting drive for discovery, Rita Joseph Abi Rached stands as a beacon of innovation, inspiring future generations to embrace sustainability, research, and the transformative power of science. Her legacy in food science and biochemistry will continue to shape the future of sustainable research, leaving a lasting impact on both academia and industry.

Daša Zupančič | Cellular Neuroscience | Best Researcher Award

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Assoc. Prof. Dr. Daša Zupančič | Cellular Neuroscience | Best Researcher Award

Assoc. Prof. Dr. Daša Zupančič, Faculty of Medicine, University of Ljubljana, Slovenia.

Daša Zupančič is a distinguished academic and researcher specializing in cell biology, urothelial pathology, and medical education. Her extensive contributions to scientific research, particularly in the field of urothelial repair and cancer transformation, have earned her recognition, including the EMBO award. She has played a crucial role in mentoring and teaching, guiding future generations of researchers and medical professionals.

Profile

Orcid

✨ Early Academic Pursuits ✨

Daša Zupančič embarked on her academic journey with an unwavering passion for cell biology and medicine. She earned her Master’s degree in 2002 from the University of Ljubljana, Faculty of Medicine, where she meticulously explored cellular and molecular biological changes in the rat bladder urothelium following cyclophosphamide exposure. This formative research laid the foundation for her Ph.D., which she successfully completed in 2006, investigating the protective role of melatonin in urothelial injury and repair. Her dedication to advancing biomedical knowledge was evident from the very beginning of her scholarly career.

🎓 Professional Endeavors 🎓

Since 2006, Daša Zupančič has been an esteemed Associate Professor at the University of Ljubljana, Faculty of Medicine, Institute of Cell Biology. Prior to this, she gained valuable experience as a Young Researcher and Teaching Assistant from 1999 to 2006. Her extensive expertise and commitment to education have made her an integral part of the institution, where she continuously fosters scientific curiosity and excellence among students and colleagues alike.

🎡 Contributions and Research Focus 🎡

Throughout her career, Daša Zupančič has dedicated her research to understanding cellular mechanisms in urothelial biology and pathology. Her investigations into cyclophosphamide-induced urothelial injury, melatonin’s protective effects, and retinoid signaling pathways in urothelial cancer transformation have provided valuable insights into cellular repair processes. Her work extends beyond laboratory research, influencing the medical community’s approach to urothelial diseases and potential therapeutic advancements.

🏆 Accolades and Recognition 🏆

Her exceptional contributions to biomedical research have been recognized on multiple platforms. In 2017, she was honored with the prestigious EMBO award for her short-term scholarship project on the role of the retinoid signaling pathway in urothelial cancer transformation. This recognition underscores her significant impact on the scientific community and highlights her pioneering approach to understanding cancer pathophysiology.

👨‍🎓 Impact and Influence 👨‍🎓

A dedicated mentor, Daša Zupančič has guided numerous students towards academic excellence. Between 2014 and 2025, she has successfully mentored four master’s students and is currently supervising two more. In addition, she has overseen the research endeavors of four Ph.D. candidates, with one having successfully defended their dissertation in 2023 and another expected to graduate in 2025. Her mentorship has shaped the next generation of biomedical researchers, fostering a culture of rigorous inquiry and scientific discovery.

📚 Legacy and Future Contributions 📚

Beyond her research, Daša Zupančič plays a pivotal role in academia through her extensive teaching engagements. Since 2000, she has been a cornerstone of education at the University of Ljubljana, contributing to multiple faculties, including Medicine, Biotechnical Sciences, Health Sciences, and Pharmacy. She teaches a range of graduate and doctoral courses, covering essential subjects such as Medical Cell Biology, Immunology, and Research in Medicine. Her dedication to education ensures that her knowledge and expertise continue to shape the minds of aspiring medical professionals and researchers for years to come.

Publication

  • Vitamin A‐Enriched Diet Increases Urothelial Cell Proliferation by Upregulating Itga3 and Areg After Cyclophosphamide‐Induced Injury in Mice
    Authors: Brina Dragar, Simona Kranjc Brezar, Maja Čemažar, Tanja Jesenko, Rok Romih, Mateja Erdani Kreft, Tadeja Kuret, Daša Zupančič
    Year: 2025

 

  • Selective Targeting of Lectins and Their Macropinocytosis in Urothelial Tumours: Translation from in vitro to ex vivo
    Authors: Nataša Resnik, Tanja Višnjar, Tomaž Smrkolj, Mateja Erdani Kreft, Rok Romih, Daša Zupančič
    Year: 2023

 

  • Nanodiamonds as Possible Tools for Improved Management of Bladder Cancer and Bacterial Cystitis
    Authors: Daša Zupančič, Peter Veranič
    Year: 2022

 

  • Transmission Electron Microscopy Demonstration of Reduced Endothelial Glycocalyx in Severe Preeclampsia
    Authors: Mugerli S, Zupančič D, Rok Romih, Lučovnik M
    Year: 2022

 

  • Vitamin A and Retinoids in Bladder Cancer Chemoprevention and Treatment: A Narrative Review of Current Evidence, Challenges and Future Prospects
    Authors: Larisa Tratnjek, Jera Jeruc, Rok Romih, Daša Zupančič
    Year: 2021

 

  • Immunohistochemistry as a Paramount Tool in Research of Normal Urothelium, Bladder Cancer and Bladder Pain Syndrome
    Authors: Daša Zupančič, Rok Romih
    Year: 2021

 

  • Combined Lectin- and Immuno-Histochemistry (CLIH) for Applications in Cell Biology and Cancer Diagnosis: Analysis of Human Urothelial Carcinomas
    Authors: Daša Zupančič
    Year: 2020

 

  • Vitamin A Rich Diet Diminishes Early Urothelial Carcinogenesis by Altering Retinoic Acid Signaling
    Authors: Daša Zupančič, Jelena Korać-Prlić, Mateja Erdani Kreft, Lucija Franković, Katarina Vilović, Jera Jeruc, Rok Romih, Janoš Terzić
    Year: 2020

 

  • Lectins as Possible Tools for Improved Urinary Bladder Cancer Management
    Authors: Daša Zupančič
    Year: 2019

 

  • Co-Culturing Porcine Normal Urothelial Cells, Urinary Bladder Fibroblasts and Smooth Muscle Cells for Tissue Engineering Research
    Authors: Daša Zupančič
    Year: 2018

 

🌟 Conclusion 🌟

With a career dedicated to pioneering research, impactful mentorship, and transformative education, Daša Zupančič continues to leave a lasting legacy in the scientific and academic communities. Her work not only enhances understanding of urothelial biology but also inspires innovation and discovery among young scientists. As she continues her academic and research endeavors, her influence on the field will undoubtedly grow, shaping the future of biomedical sciences.