Rosario Osta | Molecular and Cellular Neuroscience | Best Researcher Award

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Prof.Dr. Rosario Osta | Molecular and Cellular Neuroscience | Best Researcher Award

Prof. Dr. Rosario Osta, CIBERNED-Fundación Instituto de Investigación Sanitaria de Aragón-Universidad de Zaragoza,  Spain.

Prof. Rosario Osta Pinzolas is a distinguished geneticist and full professor at the University of Zaragoza, Spain. Her academic roots in veterinary sciences and a Ph.D. in Genetics laid the foundation for a prolific career in biomedical research, particularly in the fields of neuroscience and genetic disorders. With leadership roles in multiple high-profile research consortia such as CIBERNED, TRICALS, and ENCALS, she has established herself as a central figure in neurodegenerative disease research. Her scholarly output includes over 100 indexed publications, multiple national and international research projects, and an h-index exceeding 45.

Profile

Orcid 

Scopus

 

🎓 Early Academic Pursuits

Rosario Osta Pinzolas began her academic journey with a solid foundation in veterinary sciences, graduating as Licenciada en Veterinaria from the University of Zaragoza in 1989. Her academic inclinations quickly shifted toward molecular genetics, leading her to complete a Ph.D. in Genetics at the same university in 1994. Her early studies were driven by a deep curiosity about the mechanisms of heredity and gene expression, setting the tone for a lifelong commitment to biomedical research. These formative years cultivated her scientific rigor and sowed the seeds for a career that would eventually bridge basic science and translational medicine.

🧬 Professional Endeavors in Genetics and Biomedicine

Prof. Osta currently holds the esteemed title of Catedrática (Full Professor) in the Department of Anatomy, Embryology, and Genetics at the Faculty of Veterinary Medicine, University of Zaragoza. Since 2018, she has led her department with a focus on integrative biomedical sciences. She is the principal investigator of the LAGENBIO group recognized by both the Aragon Health Research Institute and the Government of Aragon. Under her leadership, the group has developed two major subprograms: TERAGEN and REGENERAGEN. As coordinator of the “Neuroscience and Mental Health Program” at IISA, she has spearheaded numerous efforts to understand and address neurological diseases through genetic approaches.

🧠 Contributions and Research Focus in Neuroscience

A prominent figure in neuroscience, Prof. Osta’s research lies at the intersection of genetics and neurodegeneration. She is currently the principal investigator of the only Aragon-based group within CIBERNED (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas), reflecting her national influence. Her team represents Zaragoza in prominent European consortia such as TRICALS and ENCALS, both focused on amyotrophic lateral sclerosis (ALS) and other motor neuron diseases. Through more than 100 indexed publications, predominantly in top-tier journals, her work delves into the molecular underpinnings of neurological disorders and explores regenerative medicine strategies, thereby contributing to innovative therapeutic avenues.

🧪 Accolades and Recognition in Scientific Excellence

Prof. Osta’s academic and research career has been punctuated by consistent recognition. She has completed five research productivity periods and one technology transfer period, acknowledged by CNEAI — a mark of sustained scientific impact. She has led over 74 research projects and contributed to more than 100 collaboration contracts, earning her four competitive research awards from respected institutions including CORIS, AREA, IIS, and SEBBM. Her contributions have been lauded not only for scientific quality but also for practical relevance in biomedical advancements.

🚀 Innovation and Impact in Translational Research

An ardent advocate for science with societal impact, Prof. Osta has significantly contributed to technology transfer. She holds nine patents, five of which have been licensed to industry partners. Her collaborations with companies have led to meaningful translational outputs, emphasizing her role in bridging the gap between academic research and real-world solutions. As former Director of the Technology Transfer and Innovation Secretariat at the University of Zaragoza for nearly a decade, she played a crucial role in institutional innovation strategies. Her involvement in joint university-company chairs and her role in the UZ Technology-Based Business Creation Committee for over 12 years further underscore her influence on academic entrepreneurship.

📚 Mentorship and Educational Leadership

Beyond the lab, Prof. Osta has left a profound mark as an educator and mentor. Since 2013, she has coordinated the Interuniversity Doctoral Program in Biomedical and Biotechnological Sciences, a joint initiative between the Universities of Zaragoza and La Rioja. Her mentorship includes the supervision of 13 Ph.D. theses — 9 of which earned international distinction and 6 received extraordinary doctoral awards. Her influence extends to guiding numerous undergraduate and master’s theses, fostering a new generation of scientists with a deep commitment to research excellence and innovation.

🌍 Legacy and Future Contributions

Prof. Rosario Osta’s legacy is defined by her ability to integrate scientific discovery, mentorship, and innovation. As a member of the Scientific Committee of the Luzón Foundation, her vision reaches beyond academia into public health advocacy and strategic research planning. With nearly 19,000 citations on Google Scholar and an h-index of 45, her work continues to inspire and inform global research communities. Her continued leadership in collaborative European projects ensures her contributions will shape the future of neuroscience, genetics, and translational medicine for years to come.

Publication

Title: Novel FKBP prolyl isomerase 1A (FKBP12) ligand promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice
Authors: L. Moreno-Martinez, N. Gaja-Capdevila, L. Mosqueira-Martín, R. Osta, F.J. Gil-Bea
Year: 2025

Title: Identifying Hub Genes and miRNAs Associated with Alzheimer’s Disease: A Bioinformatics Pathway to Novel Therapeutic Strategies
Authors: E. Gascón, A.C. Calvo, N. Molina, P. Zaragoza, R. Osta
Year: 2024

Title: Comparative Blood Profiling Based on ATR-FTIR Spectroscopy and Chemometrics for Differential Diagnosis of Patients with Amyotrophic Lateral Sclerosis—Pilot Study
Authors: K. Tkachenko, J.M. González Sáiz, A.C. Calvo, R. Osta, C. Pizarro Millán
Year: 2024

Title: Sex differences on constitutive long non-coding RNA expression: Modulatory effect of estradiol and testosterone in muscle cells
Authors: T. López-Royo, L. Moreno-Martinez, L. Moreno-García, R. Manzano, R. Osta
Year: 2024

Title: Differentially expressed lncRNAs in SOD1 G93A mice skeletal muscle: H19, Myhas and Neat1 as potential biomarkers in amyotrophic lateral sclerosis
Authors: T. López-Royo, L. Moreno-Martinez, P. Zaragoza, R. Manzano, R. Osta
Year: 2024

Title: Proteomic profiling of human plasma extracellular vesicles identifies PF4 and C1R as novel biomarker in sarcopenia
Authors: P. Aparicio, D. Navarrete-Villanueva, A. Gómez-Cabello, R. Osta, R. Manzano
Year: 2024

Title: Sporadic Amyotrophic Lateral Sclerosis Skeletal Muscle Transcriptome Analysis: A Comprehensive Examination of Differentially Expressed Genes
Authors: E. Gascón, P. Zaragoza, A.C. Calvo, R. Osta
Year: 2024

Title: Intermediate Repeat Expansion in the ATXN2 Gene as a Risk Factor in the ALS and FTD Spanish Population
Authors: D. Borrego-Hernández, J.F. Vázquez-Costa, R. Domínguez Rubio, M. Povedano, A. García-Redondo
Year: 2024

Title: New Insights into Endogenous Retrovirus-K Transcripts in Amyotrophic Lateral Sclerosis
Authors: L. Moreno-Martinez, S. Macías-Redondo, M.H.P. Strunk, R. Osta, J. Schoorlemmer
Year: 2024

Title: Analysis of Plasma-Derived Exosomal MicroRNAs as Potential Biomarkers for Canine Idiopathic Epilepsy
Authors: M. García-Gracia, L. Moreno-Martinez, A. Hernaiz, S. García-Belenguer, I. Martín-Burriel
Year: 2024

🏆 Conclusion

Based on her outstanding research contributions, innovation in translational science, mentorship record, and leadership within national and European research programs, Prof. Rosario Osta Pinzolas is an exceptionally strong candidate for the Best Researcher Award. Her profile reflects not only academic excellence but also societal impact and visionary leadership. While there is room for enhanced global outreach, her sustained achievements and contributions make her highly deserving of this prestigious recognition.

Lijuan Song | Cellular Neuroscience | Best Researcher Award

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Prof. Lijuan Song | Cellular Neuroscience | Best Researcher Award

Prof. Lijuan Song,  Shanxi University of Chinese Medicine, China.

Throughout my career, I have passionately committed myself to integrating traditional Chinese medicine and Western medicine to advance the prevention and treatment of brain diseases, particularly ischemic cerebrovascular diseases and neurodegenerative disorders. By leading 14 national and provincial-level research projects, publishing over 130 academic papers, and contributing significantly to educational reform, I have built a strong foundation of scientific innovation and clinical excellence. With achievements recognized both nationally and internationally, and a consistent focus on combining research, teaching, and clinical work, I have significantly impacted the fields of neuroprotection and integrative medicine.

Profile

Scopus

 

🎓 Early Academic Pursuits

From the outset of my academic journey, I committed myself to the profound study of both traditional Chinese medicine and Western medicine, aspiring to bridge these two disciplines for the betterment of brain disease treatment. I pursued a rigorous path of education and research, laying a strong foundation that later allowed me to integrate diverse medical perspectives. Early in my career, I developed a particular interest in ischemic cerebrovascular diseases and neurodegenerative conditions, setting the stage for my lifelong mission to innovate in these critical areas.

🩺 Professional Endeavors

My professional career has been a dynamic blend of teaching, clinical practice, and scientific research, with a special focus on the prevention and treatment of brain diseases. I have successfully presided over 14 prestigious national and provincial-level projects, including those funded by the National Natural Science Foundation of China and the China Postdoctoral Science Foundation. Through my work, I have consistently emphasized the value of integrating traditional Chinese medicine with modern Western practices, ensuring that my clinical and research contributions are both culturally rooted and globally relevant.

🔬 Contributions and Research Focus

Throughout my research journey, I have concentrated on ischemic cerebrovascular diseases and neurodegenerative diseases, pioneering integrated approaches for their prevention and treatment. I have published 133 scientific papers, including 45 in SCI-indexed journals, with nearly 700 citations and an H-index of 15. One of my papers published in Neural Regeneration Research (NRR) has been recognized in the ESI highest citation list, achieving an impressive 97 citations. Beyond scientific research, I have also contributed significantly to educational innovation, authoring educational reform articles in the China Journal of Traditional Chinese Medicine and editing influential academic books.

🏆 Accolades and Recognition

My dedication to scientific advancement and education has earned me multiple prestigious honors. As the first author, I received the First Prize of the Academic Achievement Award from the China Association for the Promotion of Traditional Chinese Medicine Research. I have secured three authorized patents and two software copyrights, further showcasing my commitment to innovation. Additionally, my work has been featured through oral presentations at internationally renowned academic forums such as the Autoimmunity Congress and the World Stroke Congress, and recognized by respected platforms like Logic Neuroscience and Neuroweekly.

🌍 Impact and Influence

My influence extends beyond academia into public science education and medical philosophy dialogues. I have been repeatedly invited to deliver popular science talks and academic lectures at events like the Medical Philosophy Expert Meeting Room. My presentation at the 2022 International Neural Regeneration Summit Forum earned the Most Popular Award, affirming my ability to translate complex research into impactful and accessible knowledge for diverse audiences.

📚 Legacy in Education and Publishing

In addition to research and clinical achievements, I have made significant contributions to academic publishing and educational reform. My independently authored book, Progress in Integrated Traditional Chinese and Western Medicine Prevention and Treatment of Ischemic Cerebrovascular Disease, was published by People’s Health Publishing House. I have served as the first editor-in-chief for three important books, including Exploration of Teaching Models in Higher Education Pharmaceutical Education, which was honored by its selection into the “Library of Young Scholars in Universities,” marking a lasting contribution to the future of pharmaceutical education.

🚀 Future Contributions and Aspirations

Looking ahead, I aspire to further deepen the integration of traditional Chinese and Western medicine, particularly in brain disease prevention and therapy. I am committed to leading new research directions, fostering international collaborations, and nurturing a new generation of scholars who value the richness of cross-cultural medical practices. My future endeavors will continue to reflect a relentless pursuit of scientific excellence, compassionate clinical practice, and transformative education for the global health community.

Publication

  • Title: Effect of tetramethylpyrazine on neuroinflammation after cerebral ischemia and hypoxia based on mannose-binding lectin
    Authors: Y. Duan, Yanzhe; J. Hua, Jianlin; Y. Yan, Yuqing; L. Song, Lijuan
    Year: 2025

 

  • Title: Polysaccharides from Ganoderma lucidum attenuate cognitive impairment in 5xFAD mice by inhibiting oxidative stress and modulating mitochondrial dynamics via the Nrf2/antioxidative axis activation
    Authors: J. Yu, Jiezhong; C. Ma, Cungen
    Year: 2025

 

  • Title: Hydroxysafflower yellow A alleviates the inflammatory response in astrocytes following cerebral ischemia by inhibiting the LCN2/STAT3 feedback loop
    Authors: L. Song, Lijuan; Y. Wu, Yige; L. Yin, Lijun; B. Xiao, Baoguo; C. Ma, Cungen
    Year: 2025

 

  • Title: Mechanism of senegenin in improving lipopolysacchride-induced inflammatory response of BV2 microglial cell
    Authors: B. Mu, Bingtao; M. Guo, Minfang; J. Yu, Jingwen; J. Yu, Jiezhong; L. Song, Lijuan
    Year: 2025

 

  • Title: Effectiveness and Safety of Blending Traditional Chinese Medicine With Western Medicine for Enhanced Secondary Stroke Prevention: A Meta-analysis of RCTs
    Authors: C. Wen, Chunli; L. Song, Lijuan; C. Ma, Cungen; F. Hu, Fengyun; L. Zhu, Linggqun
    Year: 2025

 

 

🎯 Conclusion

Driven by a deep belief in the power of integration between ancient wisdom and modern science, I have continuously sought to pioneer new frontiers in brain disease treatment. My work has not only advanced research but also nurtured future generations through educational contributions and public science communication. Moving forward, I remain committed to expanding the reach and depth of integrated medicine, aiming to create a lasting legacy of innovation, healing, and academic excellence for global healthcare advancement.