Joice Margareth de Almeida Rodolpho | Molecular Neuroscience | Best Researcher Award

Mrs. Joice Margareth de Almeida Rodolpho | Molecular Neuroscience | Best Researcher Award

Mrs. Joice Margareth de Almeida Rodolpho, Universidade Federal de São Carlos, Brazil.

Joice Margareth de Almeida Rodolpho is a dedicated Brazilian researcher with a strong foundation in biotechnology, parasitology, immunology, and molecular biology. She earned her Master’s and Ph.D. from the Federal University of São Carlos (UFSCar), where she explored the role of eosinophils as antigen-presenting cells in parasitic infections like Toxocara canis and Schistosoma mansoni. Her work is recognized for integrating experimental immunology with therapeutic innovations, such as the evaluation of natural plant extracts and nanomaterials for infection control. She further specialized in Flow Cytometry and Oncohematology, enhancing her analytical capabilities. With multiple awards and citations, her impactful contributions continue to strengthen Brazil’s standing in parasitological and immunological research.

Profile

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🎓 Early Academic Pursuits

Joice Margareth de Almeida Rodolpho began her academic journey in Brazil, developing a strong foundation in the life sciences. Her early interest in molecular biology and parasitology led her to pursue advanced studies at the esteemed Universidade Federal de São Carlos (UFSCar). She earned her Master’s degree in Biotechnology between 2009 and 2012, conducting significant research on Toxocara canis, particularly on the phenotypic characterization of eosinophils as antigen-presenting cells. This early work not only revealed her meticulous scientific inquiry but also laid the groundwork for her deeper exploration into immunology.

🧬 Professional Endeavors in Molecular and Evolutionary Genetics

Driven by a passion for understanding immune responses, Joice pursued a Ph.D. in Evolutionary Genetics and Molecular Biology at UFSCar from 2013 to 2017. Her doctoral research focused on the role of eosinophils as antigen-presenting cells both in vitro and ex vivo, offering vital insights into host-parasite interactions and immune regulation. Her work during this period was supported by a prestigious FAPESP scholarship, demonstrating her academic excellence and the relevance of her contributions. Under the mentorship of Professor Fernanda de Freitas Anibal, Joice refined her skills in experimental immunology and cellular biology.

🧪 Contributions and Research Focus in Parasitology and Immunopathology

Joice Rodolpho’s primary research interests lie at the intersection of parasitology, cellular immunology, and experimental pathology. Her studies explore how parasitic infections, such as those caused by Schistosoma mansoni and Toxocara canis, affect immune cell function, especially eosinophils. She has also contributed to investigations into natural plant extracts, like Mentha piperita L., assessing their therapeutic potential in modulating parasitic infections. Moreover, she extended her expertise to the field of nanomaterials, evaluating the cytotoxicity and cell death mechanisms induced by compounds like Ag₂WO₄, thus bridging classical parasitology with emerging biomedical technologies.

🏅 Accolades and Recognition in Scientific Circles

Throughout her career, Joice has received several recognitions that reflect the impact and originality of her research. In 2010, she was honored with a Menção Honrosa (Honorable Mention) for her work on Mentha piperita L. in treating Schistosoma mansoni, earning 2nd place in diagnostics and treatment. She continued to gain academic acclaim with awards at major conferences, including the VI Congresso da Sociedade Paulista de Parasitologia (2012) and the XXII B-MRS Meeting in 2024, highlighting her work on cytotoxic responses and innovative parasitological control methods. In 2024, her project on the parasitological and pathological evaluation of AW-HRL-C for schistosomiasis control was notably recognized by UNIFESP.

🧠 Impact and Influence in Experimental Immunology

Joice’s dedication to experimental immunology and cytometry has allowed her to mentor and influence upcoming researchers, especially in specialized fields such as flow cytometry. Her recent specialization in Immunology and Oncohematology by Flow Cytometry (2021–2022) at IPESSP further enriched her profile, showcasing her commitment to continuous learning and application of advanced technologies in immune profiling. Her ability to merge classical immunopathology with state-of-the-art cytometric tools reflects her versatility and forward-thinking scientific approach.

🌱 Legacy and Future Contributions in Biomedical Science

Poised to make lasting contributions, Joice Margareth de Almeida Rodolpho stands at the forefront of research into host-pathogen interactions, parasitic disease management, and immune cell function modulation. Her unique interdisciplinary approach—integrating molecular biology, natural product pharmacology, and immunological techniques—positions her as a valuable contributor to both academic research and potential therapeutic advancements. She is expected to lead innovative research in the treatment of neglected tropical diseases and immunological disorders, with implications for global health.

🔬 Research Field Relevance and Scientific Identity

As a scholar deeply embedded in the Brazilian scientific ecosystem, Joice’s identity is reflected in her multiple citation forms, indicating her widespread academic collaborations and international visibility. Her expertise bridges evolutionary genetics, biotechnology, cytometry, and immunoparasitology—making her a multifaceted researcher. Her contributions are cited under various names such as “RODOLPHO, JOICE M. A.” and “Joice Margareth de Almeida Rodolpho,” reflecting a robust presence in scholarly literature and ensuring her work continues to guide parasitological and immunological research for years to come.

Publication

  • Title: Biomarkers and Mental Disorders: A Relevance Analysis Using a Random Forest Algorithm
    Authors: Joice M. A. Rodolpho; Krissia F. Godoy; Bruna D. L. Fragelli; Jaqueline Bianchi; et al.
    Year: 2025

 

  • Title: Death Risk Score Model of Hospitalized COVID‐19 Patients: A Cohort Study
    Authors: Gustavo A. Cruz; Thais B. Boteon; Henrique Pott; Joice M. A. Rodolpho; et al.
    Year: 2025

 

  • Title: Synergistic Antifungal Effect and In Vivo Toxicity of a Monoterpene Isoespintanol Obtained from Oxandra xylopioides Diels
    Authors: Orfa I. C. Martínez; Alberto Angulo; Joice Rodolpho; Krissia F. Godoy; et al.
    Year: 2024

 

  • Title: Synergistic Antifungal Effect and In Vivo Toxicity of the Monoterpene Isoespintanol Obtained from Oxandra xylopioides Diels (Preprint)
    Authors: Orfa I. C. Martínez; Alberto Angulo; Joice M. A. Rodolpho; et al.
    Year: 2024

 

  • Title: Carbon Black CB-EDA Nanoparticles in Macrophages: Changes in the Oxidative Stress Pathway and in Apoptosis Signaling
    Authors: Joice M. A. Rodolpho; Krissia F. Godoy; Bruna D. L. Fragelli; et al.
    Year: 2023

 

  • Title: HGPRT and PNP: Recombinant Enzymes from Schistosoma mansoni and Their Role in Immunotherapy during Experimental Murine Schistosomiasis
    Authors: Bruna D. L. Fragelli; Ana C. Fattori; Joice M. A. Rodolpho; et al.
    Year: 2023

 

  • Title: Titanium Dioxide Nanoparticle (TiO2 NP) Induces Toxic Effects on LA-9 Mouse Fibroblast Cell Line
    Authors: Ana C. M. Fattori; Patricia Brassolatti; Joice M. A. Rodolpho; et al.
    Year: 2023

 

  • Title: Analysis of Cytotoxicity and Genotoxicity in a Short-Term Dependent Manner Induced by a New Titanium Dioxide Nanoparticle in Murine Fibroblast Cells
    Authors: Pedrino, M.; Brassolatti, P.; Joice M. A. Rodolpho; et al.
    Year: 2022

 

  • Title: Functionalized Titanium Nanoparticles Induce Oxidative Stress and Cell Death in Human Skin Cells
    Authors: Brassolatti, P.; Joice M. A. Rodolpho; Krissia F. Godoy; et al.
    Year: 2022

 

  • Title: Toxicological Effects of the Mixed Iron Oxide Nanoparticle (Fe₃O₄ NP) on Murine Fibroblasts LA-9
    Authors: Alves Feitosa, K.; Joice M. A. Rodolpho; et al.
    Year: 2022

 

🧾 Conclusion

Joice Rodolpho’s academic journey and scientific contributions reveal a researcher of high caliber, committed to advancing our understanding of host-pathogen dynamics and immune system function. Her work, grounded in rigorous experimentation and innovation, holds promise for developing novel therapies for neglected tropical diseases. With a forward-looking approach and interdisciplinary expertise, she stands out as a key contributor in biomedical science, poised to influence future discoveries in immunopathology and disease control.

Shilin Luo | Neurogenetics and Molecular Neuroscience | Best Researcher Award

Prof. Shilin Luo | Neurogenetics and Molecular Neuroscience | Best Researcher Award

Prof. Shilin Luo, Xiangya Hospital, Central South University, China.

Dr. Shilin Luo is a leading expert in neuropharmacology and medicinal chemistry, with a strong academic background in traditional Chinese medicine and modern pharmacology. His research focuses on the pathogenesis of neurodegenerative diseases and the development of innovative drug therapies. Through his work at Xiangya Hospital, Central South University, and previous research at Emory University, he has made significant contributions to understanding neurological disorders. His studies on animal models and risk genes have paved the way for novel treatment strategies, earning him international recognition.

Profile

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🎓 Early Academic Pursuits

Dr. Shilin Luo’s journey into the world of medical science began with a deep-rooted passion for understanding the complexities of neurological diseases. He earned his Bachelor’s degree in Chinese Materia Medica from Shenyang Pharmaceutical University, where he developed a strong foundation in traditional Chinese medicine and pharmacology. With an insatiable thirst for knowledge, he further pursued a Ph.D. in Medicinal Chemistry at China Pharmaceutical University, specializing in the research of active ingredients in natural products. Under the mentorship of Prof. Wencai Ye, a distinguished scholar, Dr. Luo honed his expertise in medicinal chemistry, paving the way for groundbreaking discoveries in neuropharmacology.

👨‍🎓 Professional Endeavors

To deepen his expertise, Dr. Luo embarked on postdoctoral research at Emory University’s School of Medicine in the Department of Pathology and Laboratory Medicine. Working under the esteemed Prof. Keqiang Ye, he focused on neurobiology and neuropharmacology, contributing significantly to the understanding of neurodegenerative diseases. His research provided novel insights into the molecular mechanisms underlying neurological disorders, positioning him as a leading figure in the field. He later took on a pivotal role as a professor in the Department of Neurology at Xiangya Hospital, Central South University, where he continues to mentor young scientists and advance medical research.

🧪 Contributions and Research Focus

Dr. Luo’s research is primarily dedicated to uncovering the pathogenesis of neurodegenerative diseases and developing therapeutic interventions. His work in animal models of pathogenic and risk genes for neurological disorders has been instrumental in identifying potential drug targets. By integrating traditional Chinese medicine with modern pharmacology, he has contributed to the development of innovative neuroprotective agents. His studies on the molecular mechanisms of neuronal degeneration have led to promising advancements in combating conditions such as Alzheimer’s and Parkinson’s disease.

🏆 Accolades and Recognition

Throughout his career, Dr. Luo has been widely recognized for his groundbreaking contributions to neuropharmacology. His research has been published in high-impact scientific journals, earning him international acclaim. His dedication to scientific excellence has garnered prestigious awards, and he is frequently invited to deliver keynote lectures at global conferences. His work continues to inspire fellow researchers, solidifying his reputation as a distinguished scientist in neurological drug development.

🏰 Impact and Influence

Dr. Luo’s impact extends beyond the laboratory, as he actively contributes to the medical community through mentorship and collaboration. His efforts in integrating traditional Chinese medicinal principles with cutting-edge pharmacological approaches have opened new avenues for drug discovery. His research findings have not only influenced academic discourse but have also laid the groundwork for potential clinical applications, bringing hope to patients suffering from neurodegenerative diseases.

⚛️ Legacy and Future Contributions

As a visionary scientist, Dr. Luo continues to push the boundaries of neurological research. His commitment to translational medicine aims to bridge the gap between laboratory discoveries and clinical applications. By fostering interdisciplinary collaborations and mentoring the next generation of researchers, he is shaping the future of neuropharmacology.

 

Publication

  • Disease-modifying therapies for Alzheimer’s disease: Clinical trial progress and opportunity
    Authors: Yujie Zhang, Jie Chen, Yanru Li, Bin Jiao, Shilin Luo
    Year: 2025

 

  • The role of the probiotic Akkermansia muciniphila in brain functions: insights underpinning therapeutic potential
    Authors: Ruiling Xu, Yuxuan Zhang, Shurui Chen, Yaohui Zeng, Xuan Fu, Ti Chen, Shilin Luo, Xiaojie Zhang
    Year: 2023

 

  • Nonviral delivery systems for antisense oligonucleotide therapeutics
    Authors: Si Huang, Xin-Yan Hao, Yong-Jiang Li, Jun‑Yong Wu, Da-Xiong Xiang, Shilin Luo
    Year: 2022

 

  • The Microglial membrane receptor TREM2 mediates exosome secretion to promote phagocytosis of amyloid‐β by microglia
    Authors: Si Huang, Xiaoli Liao, Junyong Wu, Xiaojie Zhang, Yamin Li, Daxiong Xiang, Shilin Luo
    Year: 2022

 

  • Correction: Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine
    Authors: Not explicitly listed
    Year: 2021

 

  • Polygonatum sibiricum Polysaccharides Protect against MPP‐Induced Neurotoxicity via the Akt/mTOR and Nrf2 Pathways
    Authors: Si Huang, Haiyan Yuan, Wenqun Li, Xinyi Liu, Xiaojie Zhang, Daxiong Xiang, Shilin Luo, Guodong Zhang
    Year: 2021

 

  • Bushen-Tiansui Formula Improves Cognitive Functions in an Aβ1–42 Fibril-Infused Rat Model of Alzheimer’s Disease
    Authors: Chenxia Sheng, Panpan Xu, Xinyi Liu, Weijun Peng, Daxiong Xiang, Shilin Luo
    Year: 2020

 

  • Osteogenesis activity of isocoumarin a through the activation of the PI3K-Akt/Erk cascade-activated BMP/RUNX2 signaling pathway
    Authors: Not explicitly listed
    Year: 2019

 

  • Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson’s Disease
    Authors: Shilin Luo, Seong Su Kang, Zhi-Hao Wang, Xia Liu, Julia X Day, Zhiping Wu, Junmin Peng, Daxiong Xiang, Wolfdieter Springer, Keqiang Ye
    Year: 2019

 

  • Puerarin-loaded PEG-PE micelles with enhanced anti-apoptotic effect and better pharmacokinetic profile
    Authors: Not explicitly listed
    Year: 2018

 

Conclusion

Dr. Luo’s unwavering dedication to neurological research continues to shape the future of neuropharmacology. His innovative approach, combining traditional medicinal insights with modern scientific advancements, has the potential to revolutionize drug development for neurodegenerative diseases. As a mentor, researcher, and pioneer in his field, his contributions will leave a lasting impact on both academia and clinical medicine, offering hope for more effective treatments in the years to come.