Hao Lai | Clinical Neuroscience | Best Researcher Award

Posted on by Neuroscientists

Prof. Dr. Hao Lai | Clinical Neuroscience | Best Researcher Award

Prof. Dr. Hao Lai, Zhongshan Hospital, Fudan University, China.

Dr. Hao Lai is a distinguished cardiovascular surgeon and researcher, currently serving as Chief Physician at Zhongshan Hospital, Fudan University. With over 20 years of clinical expertise, he specializes in aortic and cardiovascular surgery. His academic achievements include a Ph.D. in Surgery from Fudan University and significant contributions to the study of epigenetic mechanisms in thoracic aortic dissection. As a principal investigator of nationally funded projects and co-author of influential publications, Dr. Lai combines scientific rigor with clinical innovation. He has also played a key role in medical education and device development through industry collaboration.

Profile

Scopus

 

🎓 Early Academic Pursuits

Dr. Hao Lai began his academic journey with a strong foundation in medical sciences, culminating in a Ph.D. in Surgery from the prestigious Fudan University. His early academic pursuits were marked by a deep interest in cardiovascular physiology and surgical intervention, which later matured into a specialized focus on aortic diseases. His time as a doctoral candidate not only equipped him with rigorous scientific training but also ignited his lifelong commitment to solving complex clinical problems through research.

🏥 Professional Endeavors

Currently serving as Chief Physician at Zhongshan Hospital, Fudan University, Dr. Hao Lai has accumulated over two decades of extensive clinical experience in cardiovascular and aortic surgery. His professional trajectory reflects a seamless integration of surgical excellence with academic leadership. At Zhongshan Hospital, a leading institution in China, he has spearheaded several clinical programs aimed at enhancing patient outcomes in cases of thoracic aortic dissection and other high-risk cardiovascular conditions.

🔬 Contributions and Research Focus

Dr. Lai’s research centers around the epigenetic mechanisms underlying thoracic aortic dissection, with a particular focus on histone modification and DNA methylation. He is the Principal Investigator of a major research project funded by the National Natural Science Foundation of China, which explores the role of H3K36me3 histone modification and DNMT3B-mediated gene body methylation in the pathogenesis of aortic dissection. His scientific efforts bridge molecular pathology with clinical implications, offering new perspectives on the diagnosis and treatment of life-threatening vascular disorders.

🏆 Accolades and Recognition

A respected voice in cardiovascular medicine, Dr. Hao Lai has co-authored numerous influential articles in high-impact journals such as Cardiovascular Research and Advanced Science. His h-index of 18, as listed on Scopus, reflects his consistent scholarly output and the wide academic acknowledgment of his work. In addition, his authorship of the textbook Practical Surgery (3rd Edition), published by People’s Medical Publishing House, stands as a testament to his educational contributions to the next generation of Chinese surgeons.

🧪 Impact and Innovation

Dr. Lai’s research has made a tangible impact on the understanding and treatment of aortic diseases. His investigation into the epigenetic regulation of vascular pathology has opened new avenues for targeted therapies. Moreover, his collaboration with MicroPort Endovascular MedTech demonstrates his commitment to translating research findings into real-world applications, particularly in the development and refinement of endovascular surgical devices.

🌍 Influence and Collaboration

Beyond his direct research and surgical contributions, Dr. Lai’s influence extends into collaborative domains, both nationally and internationally. His leadership in high-level research grants, clinical trials, and industrial partnerships positions him as a central figure in the evolving landscape of cardiovascular surgery. His collaborative spirit fosters innovation and promotes cross-disciplinary dialogue, essential in today’s complex medical research environment.

🔮 Legacy and Future Contributions

As Dr. Hao Lai continues his distinguished career, his legacy is being shaped not only by his surgical accomplishments but also by his contributions to medical science. His ongoing projects are likely to further clarify the molecular landscape of aortic diseases and inspire new therapeutic strategies. Looking ahead, Dr. Lai is poised to remain at the forefront of cardiovascular innovation, committed to improving patient care through a synthesis of research, education, and clinical practice.

Publication

 

Title: Prevalence and predictors of left atrial thrombus in patients with rheumatic atrial fibrillation undergoing cardiac surgery: a cross-sectional study
Authors: J. Cui, Y. Zhang, Y. Wang, Q. Ji, C. Wang
Year: 2025


Title: A novel open-vascular single-branched stent graft in total arch repair of type A aortic dissection one-year results of a prospective multicenter randomized controlled study
Authors: J. Gu, W. Zhang, L. Kang, H. Lai, C. Wang
Year: 2025


Title: Fibroblast Activation Protein Acts as a Biomarker for Monitoring ECM Remodeling During Aortic Aneurysm via 68Ga-FAPI-04 PET Imaging
Authors: C. Hu, H. Tan, Y. Zhang, X. Chen, L. Wang
Year: 2025


Title: Mitochondrial NAD+ deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm
Authors: J. Zhang, Y. Tang, S. Zhang, K. Zhu, W. Zhang
Year: 2025


Title: Correcting mitochondrial loss mitigates NOTCH1-related aortopathy in mice
Authors: Y. Tang, J. Zhang, Y. Fang, Y. Xu, W. Zhang
Year: 2025


Title: Exploration of 68Ga-FAPI-04 PET/MR in Chronic Type B Aortic Dissection
Authors: C. Hu, Y. Zhang, S. Qiu, H. Shi, L. Wang
Year: 2025


Title: Effects of postoperative glucocorticoids on mitigation of organ dysfunction in patients with type A aortic dissection: A randomized controlled trial
Authors: M. Luo, J. Luo, X. Xu, G. Tu, Z. Luo
Year: 2024


Title: Therapeutic results of three-dimensional aortic valve anatomic repair for regurgitant bicuspid aortic valve
Authors: J. Li, C. Wang, Z. Zuo, W. Ding, T. Hong
Year: 2024


Title: 68Ga-FAPI-04 Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Ascending Aortic Aneurysm
Authors: C. Hu, H. Tan, Y. Zhang, H. Lai, L. Wang
Year: 2024


Title: Sex-based outcomes after thoracic endovascular aortic repair: A systematic review and meta-analysis
Authors: Y. Zhang, Y. Zhang, Y. Wang, L. Wang, Q. Ji
Year: 2025

✅ Conclusion

Dr. Hao Lai’s career represents a powerful blend of surgical precision, scientific insight, and academic leadership. His work has advanced the understanding of aortic diseases at the molecular level while improving surgical outcomes for patients. As he continues to mentor, innovate, and lead research at the intersection of epigenetics and cardiovascular pathology, Dr. Lai’s contributions are set to leave a lasting legacy in both clinical practice and medical science.

 

 

Nai-Bing Gu | Clinical Neuroscience | Best Researcher Award

Posted on by Neuroscientists

Prof. Dr. Nai-Bing Gu | Clinical Neuroscience | Best Researcher Award

Dr. Gu Naibing is a distinguished Chief Physician in the Department of Neurology at Xi’an Central Hospital, specializing in neuroimmunology. He has made significant contributions to the understanding of neurological diseases, particularly those related to autoimmune and inflammatory conditions of the nervous system. As a Master’s degree supervisor and an active member of several professional committees, Dr. Gu has established himself as a leader in the fields of neurology and neuroimmunology. His research, clinical expertise, and involvement in medical organizations have earned him recognition and influence in the medical community. His work continues to have a lasting impact on both the treatment of neurological diseases and the education of future healthcare professionals.

Profile

Scopus

 

👨‍⚕️ Early Academic Pursuits

Dr. Gu Naibing embarked on his academic journey with a keen interest in neurology and medicine. After completing his medical degree, he pursued further studies in the specialized field of neurology, which led to the completion of his Master’s degree. Throughout his academic tenure, Dr. Gu consistently demonstrated a strong dedication to advancing his understanding of complex neurological conditions. His early academic endeavors set the foundation for a career focused on improving patient outcomes and advancing scientific knowledge in neuroimmunology.

💼 Professional Endeavors

Dr. Gu Naibing has established himself as a prominent figure in the field of neurology. As a Chief Physician in the Department of Neurology at Xi’an Central Hospital, he plays a vital role in diagnosing and treating a wide range of neurological disorders. Additionally, he serves as a Master’s degree supervisor, contributing to the training and development of the next generation of medical professionals. His professional network includes multiple roles in prestigious committees, such as the Neuroimmunology Professional Committee of the Shaanxi Provincial International Medical Exchange Promotion Association and the Neurology Branch of the Xi’an Medical Association.

🔬 Contributions and Research Focus

Dr. Gu’s research primarily focuses on neuroimmunology, the intersection of the immune system and neurological diseases. His work has advanced understanding in this field, particularly with regard to the mechanisms underlying autoimmune disorders affecting the nervous system. By contributing to a deeper understanding of brain diseases, Dr. Gu’s research has had significant implications for the development of more effective treatments for patients suffering from conditions such as multiple sclerosis, encephalitis, and other neuroinflammatory disorders. His focus on integrating immunological and neurological disciplines has been pivotal in pushing the boundaries of clinical research.

🏆 Accolades and Recognition

Throughout his career, Dr. Gu Naibing has earned several accolades and recognition for his outstanding contributions to the medical field. His involvement in various professional committees highlights his leadership and influence in the realm of neurology and neuroimmunology. As a standing committee member of the Neuroimmunology Group and the Neurology Professional Committee of the Shaanxi Health Care Association, Dr. Gu’s expertise and leadership are regularly sought after. His recognition extends beyond clinical practice, as he is frequently invited to contribute to national and international discussions on neurological care and research.

🌍 Impact and Influence

Dr. Gu Naibing’s influence extends beyond his clinical and research activities. Through his active involvement in professional organizations, he has had a profound impact on the development of neurology and neuroimmunology practices in China. His leadership in committees, particularly within the Shaanxi Medical Communication Association, has helped bridge gaps between medical professionals, facilitating the exchange of ideas and research findings. His dedication to fostering collaboration among medical communities has contributed to the enhancement of healthcare practices and the overall improvement of patient care.

🧠 Legacy and Future Contributions

As Dr. Gu Naibing continues his work, his legacy in the fields of neurology and neuroimmunology will undoubtedly inspire future generations of healthcare professionals. His commitment to advancing both clinical and research practices ensures that his contributions will have a lasting impact on the treatment of neurological diseases. Looking ahead, Dr. Gu is poised to continue making significant strides in neuroimmunology, with ongoing research and collaborations aimed at developing new therapeutic approaches. His future contributions promise to further shape the landscape of neurological healthcare, enhancing the lives of patients around the world.

🌟 Final Thoughts

Dr. Gu Naibing’s career has been defined by his passion for neurology, his commitment to advancing research, and his tireless efforts to improve patient outcomes. As a clinician, educator, and researcher, he has earned the respect and admiration of his peers, contributing significantly to the advancement of medical knowledge and patient care. With his continued dedication to the field, Dr. Gu’s legacy is sure to endure, influencing both the scientific community and the generations of healthcare professionals who follow in his footsteps.

Publication

  • Title: Effect of BMSCs overexpressing intelectin-1 on angiogenesis in rats with cerebral infarction
    Authors: B. Zhu, K. Guo, L. Zha, L. Chang, N. Gu
    Year: 2025

 

  • Title: Salivary duct carcinoma presenting with unilateral multiple cranial nerve lesions and concurrent intracranial metastasis: A case report
    Authors: B. Zhu, Q. Zhang, K. Guo, Y. Yang, X. Jia
    Year: 2025

 

Conclusion

Dr. Gu Naibing’s career is a testament to his dedication to advancing the field of neurology and neuroimmunology. His groundbreaking research, leadership in medical committees, and commitment to education have shaped the future of neurological care in China. With his continued focus on improving patient care and expanding scientific knowledge, Dr. Gu is poised to make lasting contributions that will positively impact both the medical field and the lives of countless patients. His legacy will inspire future generations of researchers and clinicians in the realm of neurology.

 

Kiran Solingapuram Sai | Neuroimaging | Best Researcher Award

Posted on by Neuroscientists

Dr. Kiran Solingapuram Sai | Neuroimaging | Best Researcher Award

Dr. Kiran Solingapuram Sai, Wake Forest School of Medicine, United States.

Dr. Kiran K. Solingapuram Sai, PhD, is an Associate Professor with tenure in the Department of Radiology at Wake Forest School of Medicine. He holds a Ph.D. in Organic Chemistry from Northern Illinois University and has extensive research experience in radiopharmaceutical chemistry. His postdoctoral training at Washington University’s Mallinckrodt Institute of Radiology focused on radiotracer development.

Profile

Orcid

 

✨ Early Academic Pursuits

Dr. Kiran K. Solingapuram Sai embarked on his academic journey with a strong foundation in chemistry, earning a Bachelor of Science degree in Chemistry, Biochemistry, and Microbiology from Osmania University, Hyderabad, India, in 2001. His passion for organic chemistry led him to pursue a Master of Science in the same field at Osmania University, where he honed his expertise in chemical synthesis and molecular interactions. Determined to explore the depths of organic chemistry, he pursued his Ph.D. at Northern Illinois University, DeKalb, IL, under the mentorship of Dr. Douglas A. Klumpp. During this period, his research focused on synthetic methodologies and organic reaction mechanisms, paving the way for his future contributions to medicinal and radiopharmaceutical chemistry.

🌐 Professional Endeavors

Dr. Sai’s professional journey commenced with a prestigious postdoctoral research associate position at the Mallinckrodt Institute of Radiology at Washington University in St. Louis, MO, where he worked under the guidance of Dr. Robert H. Mach. During his tenure from 2010 to 2013, he delved into the complexities of radiochemistry, developing novel radiotracers and exploring their applications in medical imaging. This experience laid the groundwork for his career in radiopharmaceutical sciences. In 2014, he joined Wake Forest School of Medicine as a Research Instructor and Chief Radiochemist, marking the beginning of his significant contributions to translational imaging and radiopharmaceutical production.

⚛️ Contributions and Research Focus

At Wake Forest School of Medicine, Dr. Sai played a pivotal role in the Department of Radiology and the Clinical Translational Science Institute (CTSI). He specialized in managing clinical and research-based radiopharmaceutical production at the Wake Forest PET Research Center. As a cyclotron manager and coordinator, he oversaw the synthesis and quality control of radiotracers essential for PET imaging. His expertise extended to the development and implementation of cGMP-approved protocols for C-11 and F-18 radiopharmaceutical production, ensuring the highest standards of safety and efficacy. His research focuses on advancing PET imaging techniques, exploring new radiotracers for diagnostic and therapeutic applications, and improving imaging biomarker development.

🏆 Accolades and Recognition

Dr. Sai’s dedication to radiochemistry and molecular imaging has earned him recognition in the scientific community. His work has been instrumental in developing radiopharmaceuticals for neurological and oncological imaging, contributing significantly to early disease detection and targeted therapy. His contributions have been acknowledged through numerous research grants, collaborative projects, and publications in high-impact scientific journals. His commitment to excellence and innovation has positioned him as a leading figure in the field of radiopharmaceutical sciences.

🔬 Impact and Influence

Beyond his research and technical expertise, Dr. Sai has mentored budding scientists and researchers in the field of radiochemistry and imaging sciences. His guidance has helped shape the next generation of radiopharmaceutical experts, fostering a culture of innovation and scientific curiosity. His role in translational imaging programs has bridged the gap between basic research and clinical applications, directly impacting patient care by improving diagnostic imaging techniques.

💡 Legacy and Future Contributions

Dr. Sai’s work continues to inspire advancements in molecular imaging and radiopharmaceutical development. As an Associate Professor with tenure at Wake Forest School of Medicine, he remains dedicated to pushing the boundaries of radiochemistry, developing cutting-edge imaging agents, and enhancing the precision of diagnostic medicine. His legacy in the field is defined by his unwavering commitment to scientific discovery, translational research, and the continuous pursuit of excellence in radiopharmaceutical sciences.Dr. Kiran K. Solingapuram Sai’s contributions to the field of radiopharmaceutical chemistry stand as a testament to his dedication, innovation, and impact on medical imaging and healthcare. His journey from a passionate chemistry student to a distinguished professor and researcher highlights the transformative power of science in shaping the future of medicine.

 

Publication

  1. Radiation-induced brain injury in non-human primates: A dual tracer PET study with [11C]MPC-6827 and [11C]PiB

    • Authors: Naresh Damuka, George W. Schaaf, Mack Miller, Caleb Bradley, Bhuvanachandra Bhoopal, Ivan Krizan, Krishna K. Gollapelli, Christopher T. Whitlow, J. Mark Cline, Kiran K. Solingapuram Sai
    • Year: 2025

 

  1. The β-Secretase 1 Enzyme as a Novel Therapeutic Target for Prostate Cancer

    • Authors: Hilal A. Rather, Sameh Almousa, Ashish Kumar, Mitu Sharma, Isabel Pennington, Susy Kim, Yixin Su, Yangen He, Abdollah R. Ghara, Kiran Kumar Solingapuram Sai et al.
    • Year: 2023

 

  1. Development and Optimization of 11C-Labeled Radiotracers: A Review of the Modern Quality Control Design Process

    • Authors: Paul Josef Myburgh, Kiran Kumar Solingapuram Sai
    • Year: 2023

 

  1. Binding Parameters of [11C]MPC-6827, a Microtubule-Imaging PET Radiopharmaceutical in Rodents

    • Authors: Avinash H. Bansode, Bhuvanachandra Bhoopal, Krishna Kumar Gollapelli, Naresh Damuka, Ivan Krizan, Mack Miller, Suzanne Craft, Akiva Mintz, Kiran Kumar Solingapuram Sai
    • Year: 2023

 

  1. PET Imaging of [11C]MPC-6827, a Microtubule-Based Radiotracer in Non-Human Primate Brains

    • Authors: Naresh Damuka, Paul W. Czoty, Ashley T. Davis, Michael Nader, Susan H. Nader, Suzanne Craft, Shannon L. Macauley, Lindsey K. Galbo Thomma, Phillip M. Epperly, Christopher T. Whitlow et al.
    • Year: 2020

 

  1. One-pot synthesis of novel tert-butyl-4-substituted phenyl-1H-1,2,3-triazolo piperazine/piperidine carboxylates, potential GPR119 agonists

    • Authors: Nagaraju Bashetti, J.V. Shanmukha Kumar, Naresh Varma Seelam, B. Prasanna, Akiva Mintz, Naresh Damuka, Sriram Devanathan, Kiran Kumar Solingapuram Sai
    • Year: 2019

 

Conclusion

Dr. Kiran K. Solingapuram Sai has established himself as a leading expert in radiopharmaceutical sciences, contributing significantly to translational imaging research. His work in PET radiopharmaceutical production and quality assurance underscores his role in advancing medical imaging techniques. His academic and research contributions make him a valuable asset in the field of radiology and molecular imaging.