Mr. Alex Armstrong, University of Illinois, Urbana-Champaign, United States.
Alex Armstrong is an emerging leader in the field of systems neuroscience with a rich academic background and a global research footprint. Starting with a strong foundation in pharmacology from the University of Manchester and early research experience in China, he has built an interdisciplinary career that bridges experimental, computational, and translational neuroscience. His Ph.D. work at the University of Illinois Urbana-Champaign, under the guidance of Prof. Yurii Vlasov, focuses on the neural mechanisms of perceptual decision-making using innovative tools like tactile virtual reality and localized lesioning techniques. He has also played integral roles in teaching, mentoring, and collaborative NIH-funded research involving cutting-edge neural probes. His contributions span from fundamental neuroscience to neuroengineering, with multiple international presentations and a growing reputation in both academic and applied research communities.
Profile
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🎓 Early Academic Pursuits
Alex Armstrong’s journey into the world of neuroscience began with a strong academic foundation in Pharmacology at the University of Manchester, where he earned a BSc (Honors) degree in 2017. During his undergraduate studies, he delved into the neural effects of psychoactive substances, leading a research project examining the influence of various drugs on receptive fields in the rat lateral geniculate nucleus. His academic curiosity was not confined to the lab; Alex actively mentored disadvantaged youth in science and mathematics through the CityWise charity, demonstrating an early commitment to both education and societal impact. His academic appetite took a global turn when he received a competitive scholarship to Nanjing Medical University in China. There, he shadowed urologists and contributed to prostate cancer research by processing tumor samples and supporting manuscript preparation under the mentorship of Dr. Jian Lin. This early immersion into translational research laid the groundwork for his future endeavors in systems neuroscience.
🧠 Research Focus and Innovation
Currently pursuing his Ph.D. at the University of Illinois Urbana-Champaign, Alex Armstrong is at the forefront of neuroscience research under the mentorship of Professor Yurii Vlasov, a member of the National Academy of Engineering. His research seeks to unravel the neural underpinnings of perceptual decision-making using advanced technologies. Alex has pioneered the development of a novel tactile virtual reality system tailored for mice, enabling precise behavioral and neural investigations in ecologically valid scenarios. His contributions also include designing a localized lesioning technique to dissect the causal roles of specific cortical regions with unmatched spatial and temporal resolution. This work reflects his deep integration of behavior, electrophysiology, histology, and computational modeling — a rare confluence of skills that pushes the boundaries of systems neuroscience.
🔬 Professional Endeavors and Laboratory Leadership
Alex’s career includes impactful positions across globally renowned institutions. Prior to his doctoral studies, he served as a Research Technician at University College London, working in auditory neuroscience labs with PIs Jennifer Linden and Nicholas Lesica. There, he independently managed experiments related to auditory perception and hearing aid technology, leading both behavioral training and neural recordings. At UIUC, his laboratory involvement extends beyond individual research: he performs surgeries, manages mouse colonies, trains new graduate and undergraduate researchers, and leads collaborative NIH-funded projects investigating simultaneous electrical and chemical neural activity during seizures. Alex is a dependable pillar in the lab, bridging experiment and innovation through hands-on mentorship and project leadership.
🏆 Accolades and Recognition
Alex’s academic and scientific contributions have been recognized at multiple levels. He has presented his work through nine conference talks and poster presentations at premier forums including Barrels, the Society for Neuroscience, and AREADNE between 2021 and 2024. His visibility within the academic community extends to teaching, where he was entrusted as a Teaching Assistant for the competitive Neural Interface Engineering course (ECE421) in 2024 and 2025, guiding over 50 students through workshops, lessons, and exam reviews. His role on the UIUC neuroscience seminar committee in 2022 further demonstrated his leadership in promoting interdisciplinary dialogue, as he invited top neuroscientists from across the world to contribute to the university’s vibrant intellectual atmosphere.
🧪 Scientific Contributions and Methodological Advancements
One of Alex Armstrong’s most significant contributions lies in his ability to blend experimental neuroscience with computational modeling. His proficiency spans advanced analytical methods including Generalized Linear Models (GLM), Drift Diffusion Models (DDM), Dimensionality Reduction, and DyNetCP, positioning him at the intersection of theory and practice. His work not only provides high-resolution insights into brain function but also informs the design of next-generation neural interface devices. His leadership in testing novel neural probes capable of simultaneously recording both electrical and chemical signals underlines his commitment to tool development in neuroscience — a field critical to brain–machine interface technologies and precision neuromodulation.
🌍 Impact and Influence
Alex Armstrong’s research has both immediate and long-term scientific value. By enhancing our understanding of the cortical mechanisms underlying decision-making, his work informs the broader fields of psychology, cognitive science, and artificial intelligence. His contributions to probe testing during seizure dynamics have implications for epilepsy research, potentially opening doors for better diagnostics and treatment strategies. Furthermore, his global academic experience — spanning the U.K., U.S., and China — contributes to his inclusive scientific perspective and ability to work across cultural and institutional boundaries. He has not only advanced science but also nurtured future researchers through consistent mentoring and training roles.
🚀 Legacy and Future Contributions
Looking ahead, Alex Armstrong is poised to become a leading figure in systems neuroscience, particularly in decoding the neural basis of cognition and behavior. With a solid foundation in experimentation, programming, and tool development, he is uniquely equipped to tackle the grand challenges of brain science in the 21st century. His efforts are steadily laying a legacy of open, interdisciplinary research, bridging the biological and engineering aspects of neuroscience. Whether through innovative VR paradigms for animal behavior, high-density probe validation, or collaborative research across continents, Alex continues to pave the way for future breakthroughs in understanding the human brain.
Publication
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Title: Targeting AXL overcomes resistance to docetaxel therapy in advanced prostate cancer
Authors: JZ Lin, ZJ Wang, W De, M Zheng, WZ Xu, HF Wu, A Armstrong, JG Zhu
Year: 2017
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Title: Compression and amplification algorithms in hearing aids impair the selectivity of neural responses to speech
Authors: AG Armstrong, CC Lam, S Sabesan, NA Lesica
Year: 2022
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Title: The hearing aid dilemma: amplification, compression, and distortion of the neural code
Authors: A Armstrong, CC Lam, S Sabesan, NA Lesica
Year: 2020
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Title: Nonlinear sensitivity to acoustic context is a stable feature of neuronal responses to complex sounds in auditory cortex of awake mice
Authors: M Akritas, AG Armstrong, JM Lebert, AF Meyer, M Sahani, JF Linden
Year: 2024
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Title: Contextual modulation is a stable feature of the neural code in auditory cortex of awake mice
Authors: M Akritas, AG Armstrong, JM Lebert, AF Meyer, M Sahani, JF Linden
Year: 2023
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Title: Neuropeptides in the Extracellular Space of the Mouse Cortex Measured by Nanodialysis Probe Coupled with LC-MS
Authors: K Li, W Shi, Y Tan, Y Ding, A Armstrong, Y Vlasov, J Sweedler
Year: 2025
✅ Conclusion
Alex Armstrong exemplifies the next generation of neuroscientists—technically skilled, globally experienced, and intellectually versatile. His ability to merge behavioral neuroscience with advanced computational tools and engineering innovations positions him at the forefront of brain research. As he continues to contribute to our understanding of neural dynamics and brain–machine interfaces, Alex is set to leave a lasting impact on neuroscience and its applications in medicine and technology. His trajectory reflects not just scientific excellence, but also a commitment to mentorship, interdisciplinary collaboration, and innovation-driven discovery.