Aiying Zhang | Computational Neuroscience | Best Researcher Award

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Assist. Prof. Dr. Aiying Zhang | Computational Neuroscience | Best Researcher Award

Assist. Prof. Dr. Aiying Zhang, University of Virginia, United States.

Dr. Aiying Zhang is a rising scholar in the field of mental health data science, currently serving as an Assistant Professor at the University of Virginia and a Faculty Member at the UVA Brain Institute. Her academic foundation spans statistics, biomedical engineering, and clinical biostatistics, acquired from esteemed institutions including USTC, Tulane University, and Columbia University. Her research focuses on developing advanced computational and statistical tools—such as graphical models and multimodal fusion—to decode complex brain data from imaging and genetics. She applies these innovations to better understand and predict psychiatric conditions such as schizophrenia and Alzheimer’s disease. Her work is distinguished by its interdisciplinary nature, translational relevance, and potential to reshape clinical approaches to mental health.

Profile

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🎓 Early Academic Pursuits

Aiying Zhang’s journey into the realm of data science and mental health research began with a strong foundation in quantitative sciences. She earned her Bachelor of Science degree in Statistics from the prestigious School for the Gifted Young at the University of Science and Technology of China (USTC) in 2014. Driven by a passion for biomedical innovation and its intersection with human health, she pursued a Ph.D. in Biomedical Engineering from Tulane University, which she completed in 2021. Her graduate years were marked by deep inquiry into statistical modeling and neuroimaging, laying the groundwork for her later interdisciplinary research. She further honed her expertise through postdoctoral training in Clinical Biostatistics and Psychiatry at Columbia University Irving Medical Center, where she blended statistical rigor with clinical insight.

💼 Professional Endeavors

Dr. Zhang is currently an Assistant Professor of Data Science at the University of Virginia, where she has been on the tenure-track faculty since August 2023. She also holds a concurrent position as a Faculty Member at the UVA Brain Institute, underscoring her active role in advancing brain research across institutional boundaries. Prior to her academic appointment at UVA, she served as a Research Scientist II at the New York State Psychiatric Institute, contributing to high-impact psychiatric research. Her professional journey also includes research assistantships at Tulane University and the University of Florida, roles in which she cultivated strong collaborative and translational research skills.

🧠 Contributions and Research Focus

Dr. Zhang’s research lies at the intersection of data science, neuroscience, and mental health. She specializes in developing advanced statistical and computational methodologies to investigate the biological underpinnings of psychiatric and neurodevelopmental disorders. Her work prominently features the use of graphical models—both directed and undirected—and machine learning techniques to analyze complex datasets, such as MRI, DTI, fMRI, MEG, and various genomic modalities including SNP and DNA methylation. Her research has contributed to a deeper understanding of conditions like schizophrenia, Alzheimer’s disease, obsessive-compulsive disorder, and anxiety disorders, through the lens of multimodal data fusion and integrative neurogenetics.

🧪 Innovation in Mental Health Data Science

A distinctive hallmark of Dr. Zhang’s scholarship is her innovative application of multimodal fusion techniques to disentangle the complexities of typical and atypical brain development. Her work leverages high-dimensional neuroimaging and genetic data to draw meaningful inferences about mental health trajectories. She is particularly focused on building interpretable models that bridge the gap between data and clinical insight, thereby enabling earlier and more precise diagnostics. By combining machine learning with biomedical expertise, her contributions pave the way for next-generation tools in psychiatry and neuroscience.

🏅 Accolades and Recognition

Throughout her academic and professional trajectory, Dr. Zhang has earned widespread respect for her analytical acumen and interdisciplinary collaborations. Her postdoctoral role at Columbia, a hub for clinical psychiatry and biostatistics, positioned her among leaders in the field and enriched her research portfolio with translational applications. Her selection as faculty at a leading institution like UVA further reflects recognition of her scholarly excellence and her potential to drive future innovations in mental health data science.

🌍 Impact and Influence

Dr. Zhang’s work has significant implications for both the scientific community and clinical practice. Her methods empower researchers and clinicians alike to draw meaningful patterns from multimodal datasets, thereby advancing precision psychiatry. Moreover, her collaborative efforts across biomedical engineering, statistics, and clinical disciplines have fostered integrative frameworks that extend beyond academic settings into real-world applications. Her contributions are helping to shape a more data-driven and personalized future in mental health care.

🔮 Legacy and Future Contributions

As she continues her academic journey, Dr. Zhang aims to expand her research frontiers by exploring dynamic brain-behavior associations and improving the interpretability of AI models in clinical contexts. With a commitment to mentorship and open science, she is building a legacy rooted in intellectual rigor, innovation, and societal relevance. Her future contributions are expected to not only deepen our understanding of mental health disorders but also inspire a new generation of data scientists dedicated to neuroscience and human well-being.

Publication

  • Leverage multimodal neuro-imaging and genetics to identify causal relationship between structural and functional connectivity and ADHD with Mendelian randomization
    C Ji, S Lee, S Sequeira, J Jin, A Zhang — 2025

 

  • Integrated brain connectivity analysis with fmri, dti, and smri powered by interpretable graph neural networks
    G Qu, Z Zhou, VD Calhoun, A Zhang, YP Wang — 2025

 

  • Altered hierarchical rank in intrinsic neural time-scales in autism spectrum disorder
    A Solomon, W Yu, J Rasero, A Zhang — 2025

 

  • A Privacy-Preserving Domain Adversarial Federated learning for multi-site brain functional connectivity analysis
    Y Zhang, L Wang, KJ Su, A Zhang, H Zhu, X Liu, H Shen, VD Calhoun, … — 2025

 

  • A Novel GNN Framework Integrating Neuroimaging and Behavioral Information to Understand Adolescent Psychiatric Disorders
    W Yu, G Qu, Y Kim, L Xu, A Zhang — 2025

 

  • A Bayesian incorporated linear non-Gaussian acyclic model for multiple directed graph estimation to study brain emotion circuit development in adolescence
    A Zhang, G Zhang, B Cai, TW Wilson, JM Stephen, VD Calhoun, YP Wang — 2024

 

  • Exploring hierarchical gradients of intrinsic neural timescales in mild cognitive impairment and Alzheimer’s disease
    A Zhang, K Wengler, X Zhu, G Horga, TE Goldberg, S Lee — 2024

 

  • Time‐varying dynamic Bayesian network learning for an fMRI study of emotion processing
    L Sun, A Zhang, F Liang — 2024

 

  • Altered hierarchical gradients of intrinsic neural timescales in mild cognitive impairment and Alzheimer’s disease
    A Zhang, K Wengler, X Zhu, G Horga, TE Goldberg, S Lee, … — 2024

 

  • Associations Between Brain Connectivity and Psychiatric Symptoms in Children: Insights into Adolescent Mental Health
    D Mutu, K Ji, X He, S Lee, S Sequeira, A Zhang — 2024

 

🧾 Conclusion

Dr. Zhang’s journey exemplifies a seamless integration of data science and neuroscience to address pressing mental health challenges. Her innovative use of multimodal data and machine learning not only contributes to scientific advancement but also enhances real-world clinical decision-making. As she continues to pioneer research at the intersection of computation and psychiatry, her influence is poised to grow, shaping the future of precision mental health care and empowering both academia and clinical practice through data-driven insights.

 

Jiwei Nie | Emerging Areas in Neuroscience | Best Researcher Award

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Dr. Jiwei Nie | Emerging Areas in Neuroscience | Best Researcher Award

Dr. Jiwei Nie, Haier Group, China.

Jiwei Nie is an accomplished Chinese researcher specializing in Artificial Intelligence-based Pattern Recognition and Intelligent Detection, with a strong focus on AI large models. His academic journey began with a Bachelor’s in Mechanical Design and Automation and evolved into a deeply integrated path through a Master’s and Ph.D. in Control Science and Engineering at Northeastern University. Throughout his doctoral research, he has made notable contributions to the field of Visual Place Recognition (VPR) for autonomous systems, publishing in prestigious journals such as IEEE Transactions on Intelligent Transportation Systems and IEEE Robotics and Automation Letters. Jiwei’s innovations—especially in lightweight, training-free image descriptors and adaptive texture fusion—have positioned him at the forefront of applied AI in robotics and automation. He has also presented at major international conferences and holds multiple patents.

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🎓 Early Academic Pursuits

 Jiwei Nie displayed a deep interest in engineering and innovation from an early age. His academic journey began at Hebei University of Science and Technology, where he pursued a Bachelor’s degree in Mechanical Design, Manufacturing, and Automation. His strong academic performance earned him first-class honors, and he graduated in July 2018. Motivated to delve deeper into the fusion of machinery and intelligence, he advanced to Northeastern University, completing his Master’s degree in Mechanical and Electronic Engineering by July 2020. Driven by a vision to integrate control systems with intelligent technologies, he enrolled in a PhD program in Control Science and Engineering under a prestigious Integrated Master-PhD track, further solidifying his expertise in the intelligent automation domain.

💼 Professional Endeavors

Jiwei’s professional development has been tightly interwoven with his academic path, where he has continuously applied theoretical insights to practical problems in Artificial Intelligence and Control Systems. As a member of the Communist Party of China, he approaches his work with a strong sense of discipline and public responsibility. His fluency in English, proven by his CET-6 certification, has enabled him to actively contribute to the global research community, engaging in international collaborations and conferences. Alongside his research, Jiwei has contributed to academic circles through mentorship roles and cross-institutional projects, making a significant impact both inside and outside his university.

🤖 Contributions and Research Focus

Jiwei Nie’s research is at the forefront of Artificial Intelligence-based Pattern Recognition and Intelligent Detection, with a special emphasis on AI Large Models. His work focuses on developing lightweight, efficient algorithms for Visual Place Recognition (VPR)—a critical capability for autonomous vehicles and robotic systems. He has pioneered new methods in saliency encoding, feature mixing, and texture fusion, leading to more robust and adaptive AI systems. Through these contributions, he has addressed real-world challenges in long-term navigation and intelligent perception, pushing the boundaries of control science and machine intelligence.

🏆 Accolades and Recognition

During his PhD, Jiwei published multiple high-impact articles in leading SCI-indexed journals. His paper in the IEEE Transactions on Intelligent Transportation Systems, titled “A Training-Free, Lightweight Global Image Descriptor for Long-Term Visual Place Recognition Toward Autonomous Vehicles”, has been particularly well-received and is ranked in Q1. Additional works in IEEE Robotics and Automation Letters have been ranked in Q2, highlighting his innovations such as MixVPR++ and Efficient Saliency Encoding. Furthermore, Jiwei’s presence has been notable at world-class conferences like ICPR, ICRA, and IROS, where he presented his work to a global audience of peers and experts. He also holds several patents, including an invention patent, and continues to submit further manuscripts to top-tier venues.

🌍 Impact and Influence

Jiwei’s research has had a significant influence on the future of intelligent transportation and autonomous systems. His development of training-free VPR models has contributed to making autonomous navigation more scalable and cost-effective, especially in dynamic environments where traditional AI systems fail. His proposed methods are not only academically rigorous but are also computationally efficient, paving the way for real-world deployment. Through his innovation and academic collaborations, he has helped bridge the gap between theoretical AI models and practical engineering applications, which is vital for industries moving toward Industry 4.0 and smart mobility solutions.

🧠 Legacy and Future Contributions

Looking ahead, Jiwei Nie aspires to deepen his research in generalized large AI models, expanding the scalability and generalization abilities of pattern recognition systems across domains beyond transportation—such as smart surveillance, industrial robotics, and medical imaging. His planned future publications and continued patent filings reflect a strong ambition to lead the next generation of intelligent systems research. Jiwei is committed to fostering innovation that aligns with both academic excellence and societal needs, aiming to establish himself as a pioneering researcher and mentor in the evolving field of intelligent detection and AI integration.

🔬 Vision in AI and Control Engineering

Jiwei Nie stands as a rising expert in the convergence of Artificial Intelligence, Control Science, and Robotic Vision, a field essential for the future of smart systems and automation. His deep technical knowledge, coupled with a strategic vision, positions him to contribute not only as a researcher but also as a thought leader in AI-driven engineering. With a career rooted in innovation and societal benefit, his trajectory points toward a legacy of breakthroughs that will influence smart cities, autonomous systems, and global AI research landscapes for years to come.

Publication

  • Title: A survey of extrinsic parameters calibration techniques for autonomous devices
    Authors: J Nie, F Pan, D Xue, L Luo
    Year: 2021

 

  • Title: A training-free, lightweight global image descriptor for long-term visual place recognition toward autonomous vehicles
    Authors: J Nie, JM Feng, D Xue, F Pan, W Liu, J Hu, S Cheng
    Year: 2023

 

  • Title: Forest: A lightweight semantic image descriptor for robust visual place recognition
    Authors: P Hou, J Chen, J Nie, Y Liu, J Zhao
    Year: 2022

 

  • Title: A novel image descriptor with aggregated semantic skeleton representation for long-term visual place recognition
    Authors: J Nie, JM Feng, D Xue, F Pan, W Liu, J Hu, S Cheng
    Year: 2022

 

  • Title: Efficient saliency encoding for visual place recognition: Introducing the lightweight pooling-centric saliency-aware VPR method
    Authors: J Nie, D Xue, F Pan, Z Ning, W Liu, J Hu, S Cheng
    Year: 2024

 

  • Title: 3D semantic scene completion and occupancy prediction for autonomous driving: A survey
    Authors: G Xu, W Liu, Z Ning, Q Zhao, S Cheng, J Nie
    Year: 2023

 

  • Title: A Novel Image Descriptor with Aggregated Semantic Skeleton Representation for Long-term Visual Place Recognition
    Authors: N Jiwei, F Joe-Mei, X Dingyu, P Feng, L Wei, H Jun, C Shuai
    Year: 2022

 

  • Title: Optic Disc and Fovea Localization based on Anatomical Constraints and Heatmaps Regression
    Authors: L Luo, F Pan, D Xue, X Feng, J Nie
    Year: 2021

 

  • Title: A Novel Fractional-Order Discrete Grey Model with Initial Condition Optimization and Its Application
    Authors: Y Liu, F Pan, D Xue, J Nie
    Year: 2021

 

  • Title: EPSA-VPR: A lightweight visual place recognition method with an Efficient Patch Saliency-weighted Aggregator
    Authors: J Nie, Q Zhào, D Xue, F Pan, W Liu
    Year: 2025

 

🔚 Conclusion

With a solid foundation in engineering and control systems and an innovative mindset in artificial intelligence, Jiwei Nie is poised to become a key figure in the evolution of intelligent automation technologies. His work contributes not only to academic theory but also to practical applications that influence the development of autonomous vehicles, intelligent detection systems, and large AI model architectures. As he approaches the completion of his Ph.D. in early 2025, Jiwei is expected to continue pushing technological boundaries, inspiring future advancements in AI research and real-world intelligent systems deployment.

Irena Roterman | Computational Neuroscience | Best Researcher Award

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Prof. Dr. Irena Roterman | Computational Neuroscience | Best Researcher Award

Prof. Dr. Irena Roterman, Jagiellonian University Medical College, Poland.

Prof. Irena Roterman-Konieczna is a distinguished scientist whose academic roots in theoretical chemistry and biochemistry evolved into groundbreaking contributions in bioinformatics. With a Ph.D. and habilitation in biochemistry, and a postdoctoral fellowship at Cornell University, she developed a unique perspective on protein structure and folding. Her most notable innovation is the Fuzzy Oil Drop (FOD) model, which simulates protein folding by incorporating environmental effects using a 3D Gaussian function to map hydrophobicity distribution. This model has wide applicability—from understanding membrane proteins and amyloids to analyzing domain-swapping and receptor anchoring.

Profile

Scopus

 

🎓 Early Academic Pursuits

Irena Roterman-Konieczna began her academic journey in theoretical chemistry at the prestigious Jagiellonian University, graduating from the Faculty of Chemistry in 1974. Her early interest in molecular structure and the physicochemical underpinnings of biological systems laid a strong foundation for her interdisciplinary career. She deepened her scientific expertise by earning a Ph.D. in biochemistry in 1984 from Nicolaus Copernicus Medical Academy in Krakow, focusing on the structure of the recombinant IgG hinge region. Her postdoctoral studies at Cornell University from 1987 to 1989, under the mentorship of Harold A. Scheraga, further shaped her academic development. There, she explored force fields used in prominent computational programs like AMBER, CHARMM, and ECEPP, bridging theoretical modeling with biomolecular reality.

🧬 Professional Endeavors in Bioinformatics

Throughout her career, Prof. Roterman-Konieczna has been at the forefront of bioinformatics, dedicating herself to unraveling the mysteries of protein structure and amyloid formation. Following her habilitation in biochemistry at the Jagiellonian University Faculty of Biotechnology in 1994 and the conferment of her professorial degree in medical sciences in 2004, she continued to pioneer innovative methods in structural bioinformatics. Her hallmark contribution, the Fuzzy Oil Drop (FOD) model, revolutionized the understanding of protein folding. The model uniquely incorporates environmental influence into folding simulations by using a 3D Gaussian function to describe hydrophobicity distribution—proposing that hydrophobic residues form a central core while hydrophilic residues remain exposed. This paradigm introduced a more realistic, dynamic framework for simulating in silico protein folding.

🧪 Contributions and Research Focus

Prof. Roterman-Konieczna’s research has explored how proteins behave not only in aqueous environments but also within membranes and under the influence of external force fields. By modifying the Gaussian-based FOD model, she extended its applicability to membrane proteins, enabling quantification of their anchoring mechanisms and mobility. Her investigations into chaperonins and domain-swapping phenomena further illustrate the power of her model to decode complex folding and protein-protein interactions. She introduced a dual-variable simulation function—accounting for both internal forces (non-bonded interactions within the protein chain) and external forces (environmental effects)—to guide structural transformation toward energy minima. These ideas are foundational in modern computational biology, where realistic folding predictions are critical for understanding disease mechanisms and therapeutic targeting.

📘 Scholarly Publishing and Intellectual Outreach

A prolific author, Prof. Roterman-Konieczna has made significant contributions to scientific literature. She has authored several influential books, many published in Open Access to promote knowledge sharing. These works include “Protein Folding In Silico” (Elsevier), “Systems Biology – Functional Strategies of Living Organism” (Springer), and “From Globular Proteins to Amyloids” (Elsevier, 2020). Her books elegantly communicate complex bioinformatic strategies, such as ligand binding site identification, protein-protein interactions, and computer-aided diagnostics. Moreover, her editorial leadership from 2005 to 2020 as Chief Editor of the journal Bio-Algorithms and Med-Systems cemented her influence in shaping interdisciplinary dialogues at the intersection of medicine, biology, and computation.

🏆 Accolades and Recognition

Prof. Roterman-Konieczna’s work has earned international acclaim. Notably, she is listed among the Top 2% scientists worldwide by Stanford University and Elsevier—a testament to her influential research and academic reputation. With 149 publications indexed in PubMed, her impact on the bioinformatics community is both broad and profound. Over the course of her career, she has also served as a mentor to 14 doctoral students, many of whom continue to contribute to research and innovation across various fields of biomedicine.

🌐 Impact and Influence

Her research has advanced global understanding of how proteins fold, interact, and misfold—a process central to neurodegenerative diseases such as Alzheimer’s. The FOD model continues to provide a computational lens for studying amyloid formation and supramolecular assemblies. Her model is also pivotal in studying receptor anchoring in membranes and exploring domain-swapping mechanisms critical to protein complex formation. By integrating thermodynamic theory, statistical modeling, and structural biology, her work bridges theoretical research with biomedical applications, pushing the boundaries of in silico experimentation.

🧭 Legacy and Future Contributions

Prof. Irena Roterman-Konieczna’s legacy is rooted in her visionary approach to molecular biology, championing models that blend computational precision with biological realism. Her commitment to open access publishing and academic mentoring reflects a deep dedication to inclusive, sustainable scientific progress. As systems biology and personalized medicine continue to evolve, her models and insights will remain cornerstones for future explorations in disease modeling, drug design, and molecular diagnostics. Her career exemplifies how interdisciplinary thinking and computational ingenuity can transform the life sciences, leaving a legacy that will guide future generations of scientists.

Publication

  • Title: Aquaporins as Membrane Proteins: The Current Status
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), D. Dułak (Dawid), G. Szoniec (Grzegorz), L. Konieczny (Leszek)
    Year: 2025

 

  • Title: DisorderUnetLM: Validating ProteinUnet for efficient protein intrinsic disorder prediction
    Authors: K. Kotowski (Krzysztof), I.K. Roterman (Irena K.), K. Stapor (Katarzyna)
    Year: 2025

 

  • Title: Protein folding: Funnel model revised
    Authors: I.K. Roterman (Irena K.), M. Slupina (Mateusz), L. Konieczny (Leszek)
    Year: 2024

 

  • Title: Domain swapping: a mathematical model for quantitative assessment of structural effects
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), D. Dułak (Dawid), L. Konieczny (Leszek)
    Year: 2024

 

  • Title: Chameleon Sequences─Structural Effects in Proteins Characterized by Hydrophobicity Disorder
    Authors: I.K. Roterman (Irena K.), M. Slupina (Mateusz), K. Stapor (Katarzyna), K. Gądek (Krzysztof), P. Nowakowski (Piotr)
    Year: 2024

 

  • Title: Transmembrane proteins—Different anchoring systems
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), L. Konieczny (Leszek)
    Year: 2024

 

  • Title: External Force Field for Protein Folding in Chaperonins─Potential Application in In Silico Protein Folding
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), D. Dułak (Dawid), L. Konieczny (Leszek)
    Year: 2024

 

  • Title: Structural features of Prussian Blue-related iron complex FeT of activity to peroxidate unsaturated fatty acids
    Authors: M. Lasota (Małgorzata), G. Zemanek (Grzegorz), O. Barczyk-Woźnicka (Olga), L. Konieczny (Leszek), I.K. Roterman (Irena K.)
    Year: 2024

 

  • Title: Editorial: Structure and function of trans-membrane proteins
    Authors: I.K. Roterman (Irena K.), M.M. Brylinski (Michal Michal), F. Polticelli (Fabio), A.G. de Brevern (Alexandre G.)
    Year: 2024

 

  • Title: Model of the external force field for the protein folding process—the role of prefoldin
    Authors: I.K. Roterman (Irena K.), K. Stapor (Katarzyna), L. Konieczny (Leszek)
    Year: 2024

 

🧠 Conclusion

Prof. Roterman-Konieczna’s career stands as a testament to how deep scientific insight and computational innovation can revolutionize biological understanding. Her FOD model not only enriches the study of protein dynamics but also provides a versatile framework for medical and pharmaceutical applications. With a legacy built on rigorous research, educational outreach, and academic leadership, her influence will continue to guide future advances in molecular biology, bioinformatics, and biomedical science.